I Guzhova

Summary

Affiliation: Institute of Cytology
Country: Russia

Publications

  1. ncbi In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance
    I Guzhova
    Laboratory of Cell Protection Mechanisms, Institute of Cytology Russian Academy of Science Tikhoretsky 4, 194064, St Petersburg, Russia
    Brain Res 914:66-73. 2001
  2. pmc Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone hsp70
    Elena Yu Komarova
    Institute of Cytology RAS, Tikhoretsky pr 4, St Petersburg 194064, Russia
    Cell Stress Chaperones 9:265-75. 2004
  3. ncbi [Induction and accumulation of HSP70 leads to formation of its complexes with other cell proteins]
    I V Guzhova
    Institute of Cytology RAS, St Petersburg
    Tsitologiia 42:647-52. 2000
  4. ncbi [Effect of heat shock on cell differentiation and apoptosis in U-937 cells]
    I V Guzhova
    Institute of Cytology RAS, St Petersburg, Russia
    Tsitologiia 42:653-8. 2000

Collaborators

  • M Tytell
  • Elena Yu Komarova
  • Boris A Margulis
  • Michael E Cheetham
  • Marina M Bulatova
  • Elena A Afanasyeva

Detail Information

Publications4

  1. ncbi In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance
    I Guzhova
    Laboratory of Cell Protection Mechanisms, Institute of Cytology Russian Academy of Science Tikhoretsky 4, 194064, St Petersburg, Russia
    Brain Res 914:66-73. 2001
    ..These results suggest that extracellular Hsp70 may provide a means by which glia can affect neuronal function, perhaps enhancing neuronal stress tolerance...
  2. pmc Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone hsp70
    Elena Yu Komarova
    Institute of Cytology RAS, Tikhoretsky pr 4, St Petersburg 194064, Russia
    Cell Stress Chaperones 9:265-75. 2004
    ..Thus, Hsp70 may act to suppress caspase-dependent apoptotic signaling through binding the precursor forms of both caspase-3 and caspase-7 and preventing their maturation...
  3. ncbi [Induction and accumulation of HSP70 leads to formation of its complexes with other cell proteins]
    I V Guzhova
    Institute of Cytology RAS, St Petersburg
    Tsitologiia 42:647-52. 2000
    ..The data demonstrate that besides its traditional target, i.e. newly synthesized or abnormal polypeptides, Hsp70 is able to bind mature, active proteins...
  4. ncbi [Effect of heat shock on cell differentiation and apoptosis in U-937 cells]
    I V Guzhova
    Institute of Cytology RAS, St Petersburg, Russia
    Tsitologiia 42:653-8. 2000
    ..It is concluded that Hsp70 accumulating in higher amounts is able to transiently protect cells of TNF-mediated cytotoxic effect by physical association with the proteins that serve as modulators of apoptosis...