Research Topics
Genomes and Genes | Sergey V GuselnikovSummaryAffiliation: Institute of Cytology and Genetics Country: Russia Publications
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Publications
The amphibians Xenopus laevis and Silurana tropicalis possess a family of activating KIR-related Immunoglobulin-like receptorsSergey V Guselnikov
Laboratory of Immunogenetics, Division of Molecular and Cellular Biology, Institute of Chemical Biology and Fundamental Medicine, Prospekt Lavrentyeva 8, Novosibirsk 630090, Russian Federation
Dev Comp Immunol 34:308-15. 2010..Our findings suggest that if KRIRs of various vertebrates have any common function at all, such a function is activating rather than inhibitory...
The Xenopus FcR family demonstrates continually high diversification of paired receptors in vertebrate evolutionSergey V Guselnikov
Institute of Cytology and Genetics, Novosibirsk, Russia
BMC Evol Biol 8:148. 2008..To better understand the evolutionary history of paired receptors, we extended the study of FcR-like genes in amphibian representatives Xenopus tropicalis and Xenopus laevis...
Expansion and diversification of the signaling capabilities of the CD2/SLAM family in Xenopodinae amphibiansSergey V Guselnikov
Laboratory of Immunogenetics, Department of Molecular and Cellular Biology, Institute of Chemical Biology and Fundamental Medicine, Prospekt Lavrentyeva 8, Novosibirsk, 630090, Russia
Immunogenetics 63:679-89. 2011..Phylogenetic analysis predicted that the CD58, CD150/SLAM, and SLAMF8 genes were maintained as single-copy genes in both mammals and amphibians, while others expanded/contracted in a lineage-specific manner...
Diversity of the FcR- and KIR-related genes in an amphibian XenopusSergey V Guselnikov
Laboratory of Immunogenetics, Institute of Cytology and Genetics, Novosibirsk 630090, Russia
Front Biosci 14:130-40. 2009..This structural diversity makes elusive the functional relationships between the highly specialized mammalian FcR and KIR genes and their homologs in nonmammalian species...
Differential expression of FCRLA in naïve and activated mouse B cellsEvdokiya S Reshetnikova
Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia
Cell Immunol 272:182-92. 2012..High expression of FCRLA in subset(s) of terminally differentiated B-cells suggests that, being an ER protein, FCRLA may participate in the regulation of immunoglobulin assembly and secretion...
