Research Topics
| Lev KisselevSummaryAffiliation: Engelhardt Institute of Molecular Biology Country: Russia Publications
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Detail Information
Publications
Translation termination and yeast prionsL L Kisselev
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow, 117984, Russia
Biochemistry (Mosc) 64:1337-41. 1999..This issue of Biochemistry (Moscow) highlights from various points of view the problem of translation termination, excluding protein folding. Yeast termination factors with prion-like properties are also considered...
Translational termination comes of ageL L Kisselev
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, 32 Vavilova, 117984, Moscow, Russia
Trends Biochem Sci 25:561-6. 2000..Post-termination events in bacteria have been clarified, linking termination, ribosomal recycling and translation initiation...
Termination of translation: interplay of mRNA, rRNAs and release factors?Lev Kisselev
Engelhardt Institute of Molecular Biology, 119991 Moscow, Russia
EMBO J 22:175-82. 2003..The tight correlation between the domain structure and different functions of eRF1 has been revealed. Independently, the role of prokaryotic RF1/2 in GTPase activity of RF3 has been deciphered, as well as RF3 function itself...
Conversion of omnipotent translation termination factor eRF1 into ciliate-like UGA-only unipotent eRF1Alim Seit-Nebi
Engelhardt Institute of Molecular Biology, Moscow, Russia
EMBO Rep 3:881-6. 2002..We assume that stop codon recognition is profoundly different by eukaryotic and prokaryotic class 1 RFs...
Highly conserved NIKS tetrapeptide is functionally essential in eukaryotic translation termination factor eRF1Ludmila Frolova
Engelhardt Institute of Molecular Biology, Moscow, Russia
RNA 8:129-36. 2002..Reduction in ribosome binding revealed for Ile62, Ser64, Arg65, and Arg68 mutants argues in favor of the essential role played by the right part of the NIKS loop in interaction with the ribosome, most probably with ribosomal RNA...
Different modes of stop codon restriction by the Stylonychia and Paramecium eRF1 translation termination factorsSergey Lekomtsev
Engelhardt Institute of Molecular Biology, Russian Academy of Sciences, Moscow 119991, Russia
Proc Natl Acad Sci U S A 104:10824-9. 2007....
Invariant amino acids essential for decoding function of polypeptide release factor eRF1Petr Kolosov
Engelhardt Institute of Molecular Biology, The Russian Academy of Sciences, 119991 Moscow, Russia
Nucleic Acids Res 33:6418-25. 2005..The data point to a pivotal role played by the YxCxxxF motif (positions 125-131) in purine discrimination of the stop codons. We speculate that eRF1 decoding site is formed by a 3D network of amino acids side chains...
Translation termination in pyrrolysine-utilizing archaeaElena Alkalaeva
Engelhardt Institute of Molecular Biology, The Russian Academy of Sciences, Vavilov str 32, Moscow 119991, Russia
FEBS Lett 583:3455-60. 2009..The second aRF1 homolog may have another unknown function. The mechanism of pyrrolysine incorporation in the Methanosarcinaceae is discussed...
Polypeptide release factors in prokaryotes and eukaryotes: same function, different structureLev Kisselev
Engelhardt Institute of Molecular Biology, 119991 Moscow, Russia
Structure 10:8-9. 2002....
C-terminal domains of human translation termination factors eRF1 and eRF3 mediate their in vivo interactionT I Merkulova
INSERM U248, Institut Curie, Paris, France
FEBS Lett 443:41-7. 1999..The human eRF1 lacking 22 C-terminal amino acids remains active as a release factor and promotes an eRF3 GTPase activity whereas C-terminally truncated eRF3 is inactive as a GTPase...
Mammalian polypeptide chain release factor and tryptophanyl-tRNA synthetase are distinct proteins- Frolova LYu
Institut Jacques Monod, Paris, France
EMBO J 12:4013-9. 1993..Consequently, mammalian WRS and eRF are different proteins, and the cDNA clone formerly assigned as encoding eRF encodes rabbit WRS...
Mammalian tryptophanyl-tRNA synthetasesL L Kisselev
Engelhardt Institute of Molecular Biology, Moscow, Russia
Biochimie 75:1027-39. 1993..For unknown reasons TrpRS is overproduced in pancreas of Ruminantia. Other data on TrpRS available so far are summarized and briefly discussed here...
