Igor Rudan

Summary

Publications

  1. pmc Ethical aspects of human biobanks: a systematic review
    Danijela Budimir
    University of Split School of Medicine, Split, Croatia
    Croat Med J 52:262-79. 2011
  2. pmc Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation
    Gordan Lauc
    Glycobiology Laboratory, Genos Ltd, Zagreb, Croatia
    PLoS Genet 6:e1001256. 2010
  3. pmc A review of selected research priority setting processes at national level in low and middle income countries: towards fair and legitimate priority setting
    Mark Tomlinson
    Department of Psychology, Stellenbosch University, South Africa
    Health Res Policy Syst 9:19. 2011
  4. pmc Assessment of the proportion of neonates and children in low and middle income countries with access to a healthcare facility: A systematic review
    Aruna Chandran
    Departments of International Health and Pediatrics, Johns Hopkins University, 615 N, Wolfe Street, Suite E8622, Baltimore, MD 21205 USA
    BMC Res Notes 4:536. 2011
  5. pmc An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children
    Tanvir Huda
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    BMC Public Health 11:S27. 2011
  6. pmc An evaluation of oxygen systems for treatment of childhood pneumonia
    Alastair G Catto
    Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, UK
    BMC Public Health 11:S28. 2011
  7. pmc A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level
    Cristian Pattaro
    Institute of Genetic Medicine, European Academy Bozen Bolzano EURAC, Bolzano, Italy
    BMC Med Genet 11:41. 2010
  8. pmc Epidemiology and etiology of childhood pneumonia
    Igor Rudan
    Croatian Centre for Global Health, University of Split Medical School, Split, Croatia
    Bull World Health Organ 86:408-16. 2008
  9. pmc Setting priorities in global child health research investments: universal challenges and conceptual framework
    Igor Rudan
    Croatian Centre for Global Health, University of Split Medical School, Soltanska 2, 21000 Split, Croatia
    Croat Med J 49:307-17. 2008
  10. pmc Setting priorities in global child health research investments: assessment of principles and practice
    Igor Rudan
    Split University School of Medicine, Split, Croatia
    Croat Med J 48:595-604. 2007

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. pmc Ethical aspects of human biobanks: a systematic review
    Danijela Budimir
    University of Split School of Medicine, Split, Croatia
    Croat Med J 52:262-79. 2011
    ..To systematically assess the existing literature on ethical aspects of human biobanks...
  2. pmc Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation
    Gordan Lauc
    Glycobiology Laboratory, Genos Ltd, Zagreb, Croatia
    PLoS Genet 6:e1001256. 2010
    ....
  3. pmc A review of selected research priority setting processes at national level in low and middle income countries: towards fair and legitimate priority setting
    Mark Tomlinson
    Department of Psychology, Stellenbosch University, South Africa
    Health Res Policy Syst 9:19. 2011
    ..abstract:..
  4. pmc Assessment of the proportion of neonates and children in low and middle income countries with access to a healthcare facility: A systematic review
    Aruna Chandran
    Departments of International Health and Pediatrics, Johns Hopkins University, 615 N, Wolfe Street, Suite E8622, Baltimore, MD 21205 USA
    BMC Res Notes 4:536. 2011
    ..abstract:..
  5. pmc An evaluation of the emerging vaccines and immunotherapy against staphylococcal pneumonia in children
    Tanvir Huda
    International Centre for Diarrhoeal Disease Research, Bangladesh, Dhaka, Bangladesh
    BMC Public Health 11:S27. 2011
    ..Currently there are at least seven vaccine and immunotherapy candidates against S. aureus in the developmental phase targeting both active and passive immunization...
  6. pmc An evaluation of oxygen systems for treatment of childhood pneumonia
    Alastair G Catto
    Centre for Population Health Sciences, College of Medicine and Veterinary Medicine, University of Edinburgh, UK
    BMC Public Health 11:S28. 2011
    ..This review aims to assess the utility of oxygen systems as a method for reducing childhood mortality from pneumonia...
  7. pmc A meta-analysis of genome-wide data from five European isolates reveals an association of COL22A1, SYT1, and GABRR2 with serum creatinine level
    Cristian Pattaro
    Institute of Genetic Medicine, European Academy Bozen Bolzano EURAC, Bolzano, Italy
    BMC Med Genet 11:41. 2010
    ..A substantial proportion of the inter-individual variability in S CR level is explicable by genetic factors...
  8. pmc Epidemiology and etiology of childhood pneumonia
    Igor Rudan
    Croatian Centre for Global Health, University of Split Medical School, Split, Croatia
    Bull World Health Organ 86:408-16. 2008
    ..Although based on limited available evidence, recent studies have identified Streptococcus pneumoniae, Haemophilus influenzae and respiratory syncytial virus as the main pathogens associated with childhood pneumonia...
  9. pmc Setting priorities in global child health research investments: universal challenges and conceptual framework
    Igor Rudan
    Croatian Centre for Global Health, University of Split Medical School, Soltanska 2, 21000 Split, Croatia
    Croat Med J 49:307-17. 2008
  10. pmc Setting priorities in global child health research investments: assessment of principles and practice
    Igor Rudan
    Split University School of Medicine, Split, Croatia
    Croat Med J 48:595-604. 2007
    ..This prioritization requires a process that is transparent, systematic, and that would take into account many perspectives and build on advantages of previous approaches...
  11. ncbi request reprint From genomic advances to public health benefits: the unbearable lightness of being stuck
    Igor Rudan
    Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health Andrija Stampar School of Medicine, University of Zagreb, Croatia
    Coll Antropol 28:483-507. 2004
    ....
  12. ncbi request reprint Childhood pneumonia deaths: a new role for health workers?
    Igor Rudan
    Croatian Centre for Global Health, University of Split Medical School, 21000 Split, Croatia
    Lancet 372:781-2. 2008
  13. ncbi request reprint New technologies provide insights into genetic basis of psychiatric disorders and explain their co-morbidity
    Igor Rudan
    Croatian Centre for Global Health, The University of Edinburgh, UK
    Psychiatr Danub 22:190-2. 2010
    ..New technologies - genome-wide association studies, imaging and the optical manipulation of neural circuits - are promising to provide novel insights and lead to new treatments...
  14. pmc Setting priorities in global child health research investments: guidelines for implementation of CHNRI method
    Igor Rudan
    Public Health Sciences, The University of Edinburgh Medical School, Teviot Place, Edinburgh, Scotland, UK
    Croat Med J 49:720-33. 2008
    ..The CHNRI method is a flexible process that enables prioritizing health research investments at any level: institutional, regional, national, international, or global...
  15. ncbi request reprint Five reasons why inbreeding may have considerable effect on post-reproductive human health
    Igor Rudan
    Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health Andrija Stampar, School of Medicine, University of Zagreb, Zagreb, Croatia
    Coll Antropol 28:943-50. 2004
    ....
  16. ncbi request reprint Inbreeding and nephrolithiasis in Croatian island isolates
    I Rudan
    School of Public Health A Stampar, University Medical School, Zagreb, Croatia
    Coll Antropol 26:11-21. 2002
    ..45 (p<0.05). The study showed that a large number of predominantly recessive genetic factors might mediate the susceptibility to formation of renal stones in humans...
  17. ncbi request reprint Lost in transition--the Island of Susak (1951-2001)
    Igor Rudan
    Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health Andrija Stampar, University of Zagreb, Zagreb, Croatia
    Coll Antropol 28:403-21. 2004
    ..The results confirmed the positive correlation between inbreeding level and blood pressure that has been reported in the literature on several occasions. The last remnants of this traditional island community will soon be lost forever...
  18. ncbi request reprint Effects of genome-wide heterozygosity on a range of biomedically relevant human quantitative traits
    Harry Campbell
    Department of Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Hum Mol Genet 16:233-41. 2007
    ..Other traits, such as age at menarche, IQ and lifespan, which have been changing during the decades of urbanization, may also have been influenced by demographic factors...
  19. pmc Genetic comparison of a Croatian isolate and CEPH European founders
    Pau Navarro
    Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK
    Genet Epidemiol 34:140-5. 2010
    ....
  20. doi request reprint Does inbreeding affect N-glycosylation of human plasma proteins?
    Ozren Polasek
    Department of Public Health, Medical School, University of Split, Soltanska 2, 210000 Split, Croatia
    Mol Genet Genomics 285:427-32. 2011
    ....
  21. doi request reprint Individual multi-locus heterozygosity is associated with lower morning plasma cortisol concentrations
    Lina Zgaga
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh EH8 9AG, UK
    Eur J Endocrinol 169:59-64. 2013
    ..We hypothesized that heterozygosity ameliorates the biological response to a given level of perceived stress, reflected in lower plasma cortisol concentrations...
  22. doi request reprint Quantifying the increase in average human heterozygosity due to urbanisation
    Igor Rudan
    Department of Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Eur J Hum Genet 16:1097-102. 2008
    ....
  23. doi request reprint A quantitative trait locus for SBP maps near KCNB1 and PTGIS in a population isolate
    Maja Barbalic
    Institute for Anthropological Research, Zagreb, Croatia
    Am J Hypertens 22:663-8. 2009
    ....
  24. pmc Historic, demographic, and genetic evidence for increased population frequencies of CCR5Delta32 mutation in Croatian Island isolates after lethal 15th century epidemics
    Zrinka Biloglav
    Andrija Stampar School of Public Health, School of Medicine, University of Zagreb, Rockefellerova 4, 10000 Zagreb, Croatia
    Croat Med J 50:34-42. 2009
    ....
  25. pmc Heritabilities of ocular biometrical traits in two croatian isolates with extended pedigrees
    Veronique Vitart
    MRC Medical Research Council Human Genetics Unit, IGMM Institute of Genetics and Molecular Medicine, Edinburgh, Scotland, United Kingdom
    Invest Ophthalmol Vis Sci 51:737-43. 2010
    ..To assess the effects of body stature and years of education, in addition to age and sex, on six oculometric traits and to estimate the heritabilities of these quantitative traits in two Croatian cross-population studies...
  26. doi request reprint Effects of isolation and inbreeding on human quantitative traits: an example of biochemical markers of hemostasis and inflammation
    Drazen Pulanic
    Department of Medicine, University Hospital Rebro, Zagreb, Croatia
    Hum Biol 80:513-33. 2008
    ..Weak associations between PGH and MLH and markers of hemostasis and inflammation suggest that their genetic control may not be highly polygenic and that they could be promising targets for genetic association studies...
  27. pmc Comparative assessment of methods for estimating individual genome-wide homozygosity-by-descent from human genomic data
    Ozren Polasek
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    BMC Genomics 11:139. 2010
    ..0625) were included in this study. All individuals were genotyped with the Illumina HumanHap300 array with 317,503 SNP markers...
  28. pmc The effect of Haemophilus influenzae type b and pneumococcal conjugate vaccines on childhood pneumonia incidence, severe morbidity and mortality
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i172-85. 2010
    ....
  29. pmc Predictive value of 8 genetic loci for serum uric acid concentration
    Grgo Gunjaca
    University of Split School of Medicine, Split, Croatia
    Croat Med J 51:23-31. 2010
    ..To investigate the value of genomic information in prediction of individual serum uric acid concentrations...
  30. pmc Inference of identity by descent in population isolates and optimal sequencing studies
    Dominik Glodzik
    MRC Institute of Genetics and Molecular Medicine MRC IGMM, MRC Human Genetics Unit, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Eur J Hum Genet 21:1140-5. 2013
    ..We find that with sample sizes of 1000 individuals from an isolated population genotyped using a dense SNP array, and with 20% of these individuals sequenced, 65% of sequences of the unsequenced subjects can be partially inferred...
  31. pmc Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers
    Gordan Lauc
    Glycobiology Laboratory, Genos, Zagreb, Croatia
    PLoS Genet 9:e1003225. 2013
    ..The results may also provide an explanation for the reported pleiotropy and antagonistic effects of loci involved in autoimmune diseases and haematological cancer...
  32. ncbi request reprint Inbreeding and susceptibility to osteoporosis in Croatian island isolates
    Igor Rudan
    School of Public Health Andrija Stampar, University Medical School, Zagreb, Croatia
    Coll Antropol 28:585-601. 2004
    ..32 in males (p < 0.001) and 0.43 in females (p < 0.001). These results indicate a trend of increased susceptibility to osteoporosis with increasing level of inbreeding in isolated communities of Croatian islands...
  33. ncbi request reprint Global and regional burden of hospital admissions for severe acute lower respiratory infections in young children in 2010: a systematic analysis
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, Edinburgh, UK
    Lancet 381:1380-90. 2013
    ..We aimed to estimate the incidence of admissions and deaths for such infections in children younger than 5 years in 2010...
  34. ncbi request reprint Variability, heritability and environmental determinants of human plasma N-glycome
    Ana Knezevic
    Department of Biochemistry and Molecular Biology, University of Zagreb, Zagreb, Croatia
    J Proteome Res 8:694-701. 2009
    ..Glycome-wide environmental determinants were also detected with statistically significant effects of different variables including diet, smoking and cholesterol levels...
  35. pmc An evaluation of the emerging interventions against Respiratory Syncytial Virus (RSV)-associated acute lower respiratory infections in children
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S30. 2011
    ..Currently there are several vaccine and immunoprophylaxis candidates against RSV in the developmental phase targeting active and passive immunization...
  36. doi request reprint Effects of aging, body mass index, plasma lipid profiles, and smoking on human plasma N-glycans
    Ana Knezevic
    University of Zagreb, Faculty of Pharmacy and Biochemistry, Ante Kovacica 1, 10000 Zagreb, Croatia
    Glycobiology 20:959-69. 2010
    ....
  37. pmc Genome-wide association study of anthropometric traits in Korcula Island, Croatia
    Ozren Polasek
    Andrija Stampar School of Public Health, School of Medicine, University of Zagreb, Croatia
    Croat Med J 50:7-16. 2009
    ..To identify genetic variants underlying six anthropometric traits: body height, body weight, body mass index, brachial circumference, waist circumference, and hip circumference, using a genome-wide association study...
  38. pmc High throughput isolation and glycosylation analysis of IgG-variability and heritability of the IgG glycome in three isolated human populations
    Maja Pucic
    Genos Ltd, Glycobiology Division, Planinska 1, 10000 Zagreb, Croatia
    Mol Cell Proteomics 10:M111.010090. 2011
    ....
  39. pmc Effects of inbreeding, endogamy, genetic admixture, and outbreeding on human health: a (1001 Dalmatians) study
    Igor Rudan
    Department of Public Health Sciences, Faculty of Medicine, University of Edinburgh, Scotland, UK
    Croat Med J 47:601-10. 2006
    ....
  40. pmc Genome-wide association study of biochemical traits in Korcula Island, Croatia
    Tatijana Zemunik
    University of Split School of Medicine, Soltanska 2, 21000 Split, Croatia
    Croat Med J 50:23-33. 2009
    ....
  41. pmc Local exome sequences facilitate imputation of less common variants and increase power of genome wide association studies
    Peter K Joshi
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom
    PLoS ONE 8:e68604. 2013
    ..The imputation improvement corresponds to an increase in effective sample size of 28-38%, for SNPs with a minor allele frequency in the range 1-3%. ..
  42. doi request reprint New loci associated with central cornea thickness include COL5A1, AKAP13 and AVGR8
    Veronique Vitart
    MRC Human Genetics Unit, IGMM, Edinburgh, UK
    Hum Mol Genet 19:4304-11. 2010
    ..These associations offer mechanistic insights into the regulation of CCT and offer new candidate genes for susceptibility to common disorders in which CCT has been implicated, including primary open-angle glaucoma and keratoconus...
  43. doi request reprint Common aberrations from the normal human plasma N-glycan profile
    Maja Pucic
    Genos Ltd, Glycobiology Division, Planinska 1, 10000 Zagreb, Croatia
    Glycobiology 20:970-5. 2010
    ..These results demonstrate the existence of specific altered glyco-phenotypes in some individuals and indicate that in some cases they might represent risk factors for the development of specific diseases...
  44. pmc Epidemiology and aetiology of maternal parasitic infections in low- and middle-income countries
    Tom Roberts
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh, Scotland, UK Joint first and joint senior authorship
    J Glob Health 1:189-200. 2011
    ..This systematic review has two aims. The first is to present the prevalence of parasitic infections in the developing world over the last 30 years and the second is to evaluate the quality and distribution of research in this field...
  45. pmc An evaluation of respiratory administration of measles vaccine for prevention of acute lower respiratory infections in children
    Daisy Higginson
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S31. 2011
    ..Aerosolised measles vaccines are now under development with the hope of challenging the delivery factors currently limiting the coverage of the existing vaccine...
  46. pmc Bayesian methods for instrumental variable analysis with genetic instruments ('Mendelian randomization'): example with urate transporter SLC2A9 as an instrumental variable for effect of urate levels on metabolic syndrome
    Paul M McKeigue
    Public Health Sciences Section, Division of Community Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
    Int J Epidemiol 39:907-18. 2010
    ....
  47. ncbi request reprint Holistic anthropological research of Hvar Islanders, Croatia--from parish registries to DNA studies in 33 years
    Pavao Rudan
    Institute for Anthropological Research, Zagreb, Croatia
    Coll Antropol 28:321-43. 2004
    ....
  48. pmc Sex-specific association of anthropometric measures of body composition with arterial stiffness in a healthy population
    Danijela Budimir
    Department of Pharmacology, University of Split School of Medicine, Split, Croatia
    Med Sci Monit 18:CR65-71. 2012
    ..Little is known, however, about the association of the anthropometric measures with arterial stiffness, especially in a healthy, generally non-obese population...
  49. doi request reprint The association between galactosylation of immunoglobulin G and body mass index
    Matea Nikolac Perkovic
    Division of Molecular Medicine, Rudjer Boskovic Institute, Zagreb, Croatia
    Prog Neuropsychopharmacol Biol Psychiatry 48:20-5. 2014
    ....
  50. pmc Epigenetic silencing of HNF1A associates with changes in the composition of the human plasma N-glycome
    Vlatka Zoldos
    University of Zagreb Faculty of Science, University of Zagreb, Zagreb, Croatia
    Epigenetics 7:164-72. 2012
    ..This study represents the first demonstration of epigenetic regulation of plasma glycome composition, suggesting a potential mechanism by which epigenetic deregulation of the glycome may contribute to disease development...
  51. ncbi request reprint Gaps in policy-relevant information on burden of disease in children: a systematic review
    Igor Rudan
    Department of Community Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
    Lancet 365:2031-40. 2005
    ....
  52. doi request reprint A complex pattern of agreement between oscillometric and tonometric measurement of arterial stiffness in a population-based sample
    Grgo Gunjaca
    Department of Pharmacology, University of Split School of Medicine, Split, Croatia
    J Hypertens 30:1444-52. 2012
    ..In a large population-based sample we performed an agreement analysis of the set of arterial stiffness indices (ASIs) measured by tonometric (SphygmoCor) and oscillometric (Arteriograph) techniques...
  53. pmc SMAD7 variant rs4939827 is associated with colorectal cancer risk in Croatian population
    Iva Kirac
    Department of Surgical Oncology, University Hospital for Tumours, Sestre milosrdnice University Hospital Centre, Zagreb, Croatia
    PLoS ONE 8:e74042. 2013
    ..Since large differences between populations exist, generalisability of findings to any specific population needs to be confirmed...
  54. doi request reprint High-throughput IgG Fc N-glycosylation profiling by mass spectrometry of glycopeptides
    Maja Pučić Baković
    Laboratory of Glycobiology, Genos Ltd, Planinska 1, 10000 Zagreb, Croatia
    J Proteome Res 12:821-31. 2013
    ..Age and sex association of glycosylation features was, to a large extent, comparable between MALDI-TOF-MS and HILIC IgG glycosylation profiling...
  55. ncbi request reprint An estimate of asthma prevalence in Africa: a systematic analysis
    Davies Adeloye
    Davies Adeloye, WHO Collaborative Centre for Population Health Research and Training, Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, EH8 9AG, UK
    Croat Med J 54:519-31. 2013
    ..To estimate and compare asthma prevalence in Africa in 1990, 2000, and 2010 in order to provide information that will help inform the planning of the public health response to the disease...
  56. pmc Epidemiology and etiology of childhood pneumonia in 2010: estimates of incidence, severe morbidity, mortality, underlying risk factors and causative pathogens for 192 countries
    Igor Rudan
    Centre for Population Health Sciences and Global Health Academy, University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 3:10401. 2013
    ..This should allow national policy-makers and stakeholders to implement proposed policies in the World Health Organization (WHO) and UNICEF member countries...
  57. pmc Genome-wide analysis of epistasis in body mass index using multiple human populations
    Wen Hua Wei
    MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Edinburgh, UK
    Eur J Hum Genet 20:857-62. 2012
    ..We conclude that genome-wide analysis of epistasis in multiple populations is an effective approach to provide new insights into the genetic regulation of BMI but requires additional efforts to confirm the findings...
  58. pmc Abundant pleiotropy in human complex diseases and traits
    Shanya Sivakumaran
    Centre for Population Health Sciences, The University of Edinburgh, Edinburgh EH8 9AG, UK
    Am J Hum Genet 89:607-18. 2011
    ....
  59. pmc An evaluation of emerging vaccines for childhood meningococcal disease
    Debajeet Choudhuri
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S29. 2011
    ..We aimed to perform a structured assessment of these emerging meningococcal vaccines as a means of reducing global meningococcal disease burden among children under 5 years of age...
  60. pmc Global estimate of the incidence of clinical pneumonia among children under five years of age
    Igor Rudan
    Department of Medical Stastistics, Epidemiology and Medical Infomatics, School of Public Health Andrija Stampar, Zagreb, Croatia
    Bull World Health Organ 82:895-903. 2004
    ..In this paper we aim to estimate the worldwide incidence of clinical pneumonia in young children...
  61. ncbi request reprint Impact analysis of a regional scientific journal (1980-2000): supporting promising local researchers pays the greatest dividends
    Pavao Rudan
    Institute for Anthropological Research, Zagreb, Croatia
    Coll Antropol 29:1-7. 2005
    ....
  62. pmc Strategy for mapping quantitative trait loci (QTL) by using human metapopulations
    Igor Rudan
    Department of Public Health Sciences, Faculty of Medicine, University of Edinburgh, Edinburgh, Scotland, UK
    Croat Med J 47:532-42. 2006
    ..In such cases, the distribution of QT measurements in an (affected) isolate is expected to deviate from that observed in neighboring isolates...
  63. ncbi request reprint Performance of WHO Angina Questionnaire in measuring burden of coronary heart disease in human isolate populations
    Zrinka Biloglav
    Department of Medical Statistics, Epidemiology and Medical Informatics, School of Public Health Andrija Stampar, School of Medicine, University of Zagreb, Zagreb, Croatia
    Coll Antropol 28:205-13. 2004
    ....
  64. doi request reprint Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, Edinburgh, UK
    Lancet 378:1917-30. 2011
    ..We aimed to estimate the global incidence of and mortality from lower respiratory infections associated with influenza in children younger than 5 years...
  65. pmc The effect of case management on childhood pneumonia mortality in developing countries
    Evropi Theodoratou
    Public Health Sciences, University of Edinburgh, Edinburgh, UK
    Int J Epidemiol 39:i155-71. 2010
    ....
  66. pmc Setting research priorities to reduce global mortality from childhood pneumonia by 2015
    Igor Rudan
    Centre for Population Health Sciences, The University of Edinburgh Medical School, Edinburgh, Scotland, United Kingdom
    PLoS Med 8:e1001099. 2011
    b>Igor Rudan and colleagues report the results of their consensus building exercise that identified health research priorities to help reduce child mortality from pneumonia.
  67. pmc Aetiology of community-acquired neonatal sepsis in low and middle income countries
    Donald Waters
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh, Scotland, UK
    J Glob Health 1:154-70. 2011
    ..This review describes and analyses the bacterial aetiology of community-acquired neonatal sepsis in developing countries...
  68. doi request reprint Complex genetic regulation of protein glycosylation
    Gordan Lauc
    University of Zagreb, Faculty of Pharmacy and Biochemistry, A Kovacica 1, HR 10000 Zagreb, Croatia
    Mol Biosyst 6:329-35. 2010
    ..In this review we present some preliminary insights into this fascinating field...
  69. ncbi request reprint Gene polymorphisms of the renin-angiotensin system and early development of hypertension
    Maja Barbalic
    Institute for Anthropological Research, Zagreb, Croatia
    Am J Hypertens 19:837-42. 2006
    ....
  70. pmc Association of nephrolithiasis and gene for glucose transporter type 9 (SLC2A9): study of 145 patients
    Ozren Polasek
    Department of Medical Statistics, Epidemiology, and Medical Informatics, Andrija Stampar School of Public Health, Medical School, University of Zagreb, Rockefellerova 4, 10000 Zagreb, Croatia
    Croat Med J 51:48-53. 2010
    ..To investigate the association of nephrolithiasis and solute carrier family 2, facilitated glucose transporter, member 9 (SLC2A9), also known as glucose transporter type 9, Glut9...
  71. pmc Risk factors for severe acute lower respiratory infections in children: a systematic review and meta-analysis
    Stewart Jackson
    Centre for Population Health Sciences, University of Edinburgh, Medical School, Edinburgh, Scotland, UK
    Croat Med J 54:110-21. 2013
    ..To identify the risk factors in children under five years of age for severe acute lower respiratory infections (ALRI), which are the leading cause of child mortality...
  72. pmc Optimizing community case management strategies to achieve equitable reduction of childhood pneumonia mortality: An application of Equitable Impact Sensitive Tool (EQUIST) in five low- and middle-income countries
    Donald Waters
    Centre for Population Health Sciences and Global Health Academy, The University of Edinburgh Medical School, Edinburgh, Scotland, UK
    J Glob Health 2:20402. 2012
    ....
  73. pmc Evidence of inbreeding depression on human height
    Ruth McQuillan
    Centre for Population Health Sciences, University of Edinburgh, Edinburgh, Scotland, United Kingdom
    PLoS Genet 8:e1002655. 2012
    ....
  74. pmc The case for launch of an international DNA-based birth cohort study
    Igor Rudan
    Centre for Population Health Sciences and Global Health Academy, University of Edinburgh, Scotland, UK Croatian Centre for Global Health, Faculty of Medicine, University of Split, Croatia
    J Glob Health 1:39-45. 2011
    ....
  75. pmc An evaluation of emerging vaccines for childhood pneumococcal pneumonia
    Julia Webster
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, UK
    BMC Public Health 11:S26. 2011
    ....
  76. pmc Runs of homozygosity in European populations
    Ruth McQuillan
    Public Health Sciences, University of Edinburgh Medical School, Edinburgh EH8 9AG, UK
    Am J Hum Genet 83:359-72. 2008
    ....
  77. doi request reprint A 'complexity' of urate transporters
    Alan F Wright
    MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Crewe Road, Edinburgh, UK
    Kidney Int 78:446-52. 2010
    ....
  78. pmc Global burden of acute lower respiratory infections due to respiratory syncytial virus in young children: a systematic review and meta-analysis
    Harish Nair
    Centre for Population Health Sciences, Global Health Academy, The University of Edinburgh, Edinburgh, UK
    Lancet 375:1545-55. 2010
    ..We aimed to estimate the global incidence of and mortality from episodes of acute lower respiratory infection (ALRI) due to RSV in children younger than 5 years in 2005...
  79. ncbi request reprint A polygenic basis for late-onset disease
    Alan Wright
    MRC Human Genetics Unit, Western General Hospital, Crewe Road, EH4 2XU, Edinburgh, UK
    Trends Genet 19:97-106. 2003
    ..The origin and nature of this variation suggests that current strategies are poorly suited to identifying genes involved in many complex diseases...
  80. ncbi request reprint Seasonality of births in Croatia
    Ozren Polasek
    Department of Medical Statistics, Epidemiology and Medical Informatics, Andrija Stampar School of Public Health, Medical School, University of Zagreb, Zagreb, Croatia
    Coll Antropol 29:249-55. 2005
    ..Regional analysis showed lack of seasonality in the capital city of Zagreb and either intermittent or stable seasonality pattern in the rest of the country...
  81. pmc Reducing bias from test misclassification in burden of disease studies: use of test to actual positive ratio--new test parameter
    Harry Campbell
    1Department of Public Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
    Croat Med J 49:402-14. 2008
    ..Those two values may be very different, their relationship depending on the properties of the diagnostic test applied and true prevalence of the disease in a population...
  82. doi request reprint Causes of deaths in children younger than 5 years in China in 2008
    Igor Rudan
    Centre for Population Health Sciences, University of Edinburgh Medical School, Edinburgh, UK
    Lancet 375:1083-9. 2010
    ..We identified the main causes of deaths in neonates (<1 month), postneonatal infants (1-11 months), and children (<5 years) in China using information that was available to the public...
  83. ncbi request reprint Youth and AIDS--a study of attitudes, knowledge, behavior and risks in the post-war Croatia
    Dino Pavicić
    Institute for Anthropological Research, Zagreb, Croatia
    Coll Antropol 27:161-72. 2003
    ..In this study, we report on a large related survey and education program among 17-year-old high school pupils that was conducted in years immediately following the War (1996-1999)...
  84. pmc Human population structure, genome autozygosity and human health
    Harry Campbell
    Centre for Population Health Sciences, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG, UK
    Genome Med 1:91. 2009
    ..The overall outcome is expected to be beneficial for a range of traits associated with human health and disease that show dominance variance...
  85. ncbi request reprint Y chromosomal heritage of Croatian population and its island isolates
    Lovorka Barac
    Institute for Anthropological Research, Zagreb, Croatia
    Eur J Hum Genet 11:535-42. 2003
    ..Interestingly, the same population also harbored mitochondrial haplogroup F that is virtually absent in European populations--indicating a connection with Central Asian populations, possibly the Avars...
  86. ncbi request reprint Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk
    Malcolm G Dunlop
    Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and Medical Research Council MRC Human Genetics Unit, Edinburgh, UK
    Nat Genet 44:770-6. 2012
    ..2 (rs5934683, near SHROOM2; P = 7.30 × 10(-10)) This brings the number of independent loci associated with CRC risk to 20 and provides further insight into the genetic architecture of inherited susceptibility to CRC...
  87. doi request reprint The TCF7L2 diabetes risk variant is associated with HbA₁(C) levels: a genome-wide association meta-analysis
    Christopher S Franklin
    Centre for Population Health Sciences, University of Edinburgh, Scotland
    Ann Hum Genet 74:471-8. 2010
    ..The strongest association was with the TCF7L2 gene (rs7903146, P= 1.48 × 10⁻⁷). This is also the strongest common genetic risk factor for T2D but it has not been identified in previous genome-wide studies of glycated haemoglobin...
  88. pmc Inbreeding and the genetic complexity of human hypertension
    Igor Rudan
    Department of Community Health Sciences, University of Edinburgh Medical School, Edinburgh EH8 9AG, Scotland, United Kingdom
    Genetics 163:1011-21. 2003
    ..The global impact of inbreeding on hypertension may be substantial since, although inbreeding is declining in Western societies, an estimated 1 billion people globally show rates of consanguineous marriages >20%...
  89. ncbi request reprint Childhood pneumonia and diarrhoea: setting our priorities right
    Igor Rudan
    Child Health and Nutrition Research Initiative, Global Forum for Health Research, Geneva, Switzerland
    Lancet Infect Dis 7:56-61. 2007
    ..We believe that only in this way will proper attention be given to delivery of proven interventions to reduce the high childhood mortality caused by pneumonia and diarrhoea...
  90. pmc Setting priorities in global child health research investments: addressing values of stakeholders
    Lydia Kapiriri
    Joint Center for Bioethics, University of Toronto Medical School, Toronto, Ontario, Canada
    Croat Med J 48:618-27. 2007
    ..To identify main groups of stakeholders in the process of health research priority setting and propose strategies for addressing their systems of values...
  91. pmc Scaling-up of training and education for health workers
    Igor Rudan
    Croat Med J 49:295-7. 2008
  92. doi request reprint SLC2A9 is a newly identified urate transporter influencing serum urate concentration, urate excretion and gout
    Veronique Vitart
    MRC Human Genetics Unit, Western General Hospital, Edinburgh EH4 2XU, UK
    Nat Genet 40:437-42. 2008
    ..SLC2A9 is a known fructose transporter, and we now show that it has strong uric acid transport activity in Xenopus laevis oocytes...
  93. pmc Setting priorities in child health research investments for South Africa
    Mark Tomlinson
    Health Systems Research Unit, Medical Research Council, Cape Town, Western Cape, South Africa
    PLoS Med 4:e259. 2007
  94. pmc For free or for fee? Dilemma of small scientific journals
    Marko Kljakovic-Gaspic
    Croat Med J 48:292-9. 2007
    ..Our experience may be similar to that of the many biomedical journals which find themselves in a dilemma whether to join major publishers or not...
  95. doi request reprint Primary health care: making Alma-Ata a reality
    John Walley
    Nuffield Centre for Health and Development, Leeds Institute of Health Sciences, University of Leeds, Leeds, UK
    Lancet 372:1001-7. 2008
    ..Progress should be measured and accountability assured. We prioritise research questions and suggest actions and measures for stakeholders both locally and globally, which are required to revitalise primary health care...
  96. ncbi request reprint Our "Collegium Antropologicum" officially the most improved social science journal in the world for mid-2002
    Pavao Rudan
    Coll Antropol 27:S1-4. 2003
    ..We hope that this is an early sign of revival of the scientific activity in our country after the War in Croatia (1991-1995)...
  97. ncbi request reprint Contribution of consanguinuity to polygenic and multifactorial diseases
    Igor Rudan
    Nat Genet 38:1224-5. 2006
  98. ncbi request reprint Methodological and quality issues in epidemiological studies of acute lower respiratory infections in children in developing countries
    Claudio F Lanata
    Instituto de Investigacion Nutricional, AP 18 0191, Lima 18, Peru
    Int J Epidemiol 33:1362-72. 2004
    ....
  99. pmc Health effects of human population isolation and admixture
    Igor Rudan
    Croat Med J 47:526-31. 2006
  100. ncbi request reprint Genetic variation at nine short tandem repeat loci among islanders of the eastern Adriatic coast of Croatia
    Irena Martinovic Klaric
    Institute for Anthropological Research, Amruseva 8, 10000 Zagreb, Croatia
    Hum Biol 77:471-86. 2005
    ..High mutation rates of the studied loci together with local drift effects are likely explanations for interisland genetic variation and the observed lack of reduced genetic diversity among the island populations...
  101. ncbi request reprint [The Mediterranean diet and occurrence of malignant tumors of the digestive system in the Croatian islands]
    Igor Rudan
    Katedra za medicinsku statistiku, epidemiologiju i medicinsku informatiku Medicinskog fakulteta Sveucilista u Zagrebu
    Lijec Vjesn 125:60-7. 2003
    ..The study showed that "Mediterranean" type of diet could have a protective effect against gastric and pancreatic cancer...