The role of the small bowel in the regulation of circulating ghrelin levels and food intake in the obese Zucker ratFrancesco Rubino
Institut de Recherche Contre les Canceurs de l Appareil Digestif European Institute of Telesurgery, 1 Place de l Hopital, 67091 Strasbourg, France
Endocrinology 146:1745-51. 2005
....
- Bariatric surgery: effects on glucose homeostasis
Francesco Rubino
IRCAD EITS European Institute of Telesurgery, University Louis Pasteur, Strasbourg, France
Curr Opin Clin Nutr Metab Care 9:497-507. 2006
..It focuses on current hypotheses about the mechanism of diabetes control after Roux-en-Y gastric bypass surgery, and discusses the relationship between gastrointestinal anatomy and glucose homeostasis...
The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetesFrancesco Rubino
IRCAD European Institute of Telesurgery, University Louis Pasteur, Strasbourg, France
Ann Surg 244:741-9. 2006
..We sought to distinguish between these two mechanisms...
- Effect of duodenal-jejunal exclusion in a non-obese animal model of type 2 diabetes: a new perspective for an old disease
Francesco Rubino
IRCAD EITS European Institue of Telesurgery, Louis Pasteur University, Strasbourg, France
Ann Surg 239:1-11. 2004
..The aim of this study was to investigate whether duodenal-jejunal exclusion can control diabetes independently on resolution of obesity-related abnormalities...
- Potential of surgery for curing type 2 diabetes mellitus
Francesco Rubino
IRCAD European Institute of Telesurgery, Strasbourg, France
Ann Surg 236:554-9. 2002
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- Endoscopic approach for carotid artery surgery
F Rubino
Minimally Invasive Surgery Center, Mount Sinai Medical Center, New York, NY 10029, USA
Surg Endosc 16:789-94. 2002
..The purpose of this study was to evaluate the feasibility of an endoscopic approach for carotid artery surgery in a large animal model...
- The early effect of the Roux-en-Y gastric bypass on hormones involved in body weight regulation and glucose metabolism
Francesco Rubino
IRCAD-EITS, Strasbourg, France
Ann Surg 240:236-42. 2004
..CONCLUSIONS: Roux-en-Y gastric bypass determines considerable hormonal changes before significant BMI changes take place. These results support the hypothesis of an endocrine effect as the possible mechanism of action of RYGB...
Metabolic surgery to treat type 2 diabetes: clinical outcomes and mechanisms of actionFrancesco Rubino
Weill Cornell Medical College New York Presbyterian Hospital, New York, New York, USA
Annu Rev Med 61:393-411. 2010
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- Laparoscopic aortorenal bypass using a PTFE graft: survival study in the porcine model
P Gentileschi
Division of Laparoscopic Surgery, Mount Sinai Medical Center, New York, New York 10029, USA
J Laparoendosc Adv Surg Tech A 11:223-8. 2001
..The short-term effect of the bypass on kidney vascularization seems promising, as demonstrated by pathologic findings. Laparoscopic aortorenal bypass could extend the indications for renal revascularization surgery...
- Gastrointestinal surgery as treatment for type 2 diabetes
Tracy Ann Moo
Weill Cornell Medical College of Cornell University New York Presbyterian Hospital, New York, New York 10065, USA
Curr Opin Endocrinol Diabetes Obes 15:153-8. 2008
..Gastrointestinal bypass surgery is now gaining awareness as a potential effective and long-term treatment...
- Metabolic surgery: the role of the gastrointestinal tract in diabetes mellitus
Francesco Rubino
Section of Gastrointestinal Metabolic Surgery, Department of Surgery, Weill Cornell Medical College New York Presbyterian Hospital, 525 East 68th Street, P 714, New York, NY 10065, USA
Nat Rev Endocrinol 6:102-9. 2010
..In light of the evidence presented here, we speculate that the gastrointestinal tract might have a role in the pathophysiology of T2DM and obesity...
- Review and case report of idiopathic lower extremity compartment syndrome and its treatment in diabetic patients
V N Pamoukian
Department of Surgery, Lenox Hill Hospital, New York, NY, USA
Diabetes Metab 26:489-92. 2000
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- "Metabolic" surgery for treatment of type 2 diabetes mellitus
Aaron P Schulman
Department of Medicine, Division of Endocrinology, Weill Cornell Medical College, New York, NY, USA
Endocr Pract 15:624-31. 2009
..To discuss the potential contribution of "metabolic" surgery in providing optimal management of patients with type 2 diabetes mellitus (T2DM)...
- Risk of gastric cancer after Roux-en-Y gastric bypass
Harutaka Inoue
Institut de Recherche Contre les Canceurs de l Appareil Digestif European Institute of Telesurgery, 1 Place de l Hopital, 67091 Strasbourg, France
Arch Surg 142:947-53. 2007
..To evaluate the risk of gastric cancer after Roux-en-Y gastric bypass (RYGB)...
- Laparoscopic total mesorectal excision (TME) for rectal cancer surgery: long-term outcomes
J Leroy
IRCAD-European Institute of Telesurgery (IRCAD-EITS, Louis Pasteur University, 1 Place de l'Hopital, 67091 Strasbourg, France
Surg Endosc 18:281-9. 2004
..23 years (95% confidence interval [CI], 5.39-7.07). CONCLUSION: Laparoscopic TME is feasible and safe. The laparoscopic approach to the surgical treatment of operable rectal cancer does not seem to entail any oncologic disadvantages...
- Safe laparoscopic surgery in the elderly
Robrecht Ceulemans
IRCAD EITS, European Institute of Telesurgery, University Louis Pasteur, 1, Place de l Hopital, 67091 Strasbourg, France
Am J Surg 187:323-7. 2004
..This study was intended to evaluate the safety of the use of a laparoscopic approach for emergency and elective surgery in elderly patients...
- The Diabetes Surgery Summit consensus conference: recommendations for the evaluation and use of gastrointestinal surgery to treat type 2 diabetes mellitus
Francesco Rubino
Department of Surgery, Section of Metabolic Surgery, Weill Cornell Medical College New York Presbyterian Hospital, New York, NY, USA
Ann Surg 251:399-405. 2010
..To develop guidelines for the use of gastrointestinal surgery to treat type 2 diabetes and to craft an agenda for further research...
- The impact of obesity on technical feasibility and postoperative outcomes of laparoscopic left colectomy
Joel Leroy
IRCAD/European Institute of Telesurgery, , Strasbourg, France
Ann Surg 241:69-76. 2005
..Our study supports the safety of using laparoscopic surgery for colorectal diseases in obese patients...
- Late gastric prolapse with pouch necrosis after laparoscopic adjustable gastric banding
Sorinel Lunca
IRCAD/EITS, University of Medicine Louis Pasteur, Strasbourg, France
Obes Surg 15:571-5. 2005
..Initial referral to a specialized center is necessary for proper care of this complication. Failure of conservative treatment mandates early operative intervention...
- Is type 2 diabetes an operable intestinal disease? A provocative yet reasonable hypothesis
Francesco Rubino
Department of Surgery, Catholic University of Rome, Rome, Italy
Diabetes Care 31:S290-6. 2008
..This article presents available evidence in support of the hypothesis that type 2 diabetes may be an operable disease characterized by a component of intestinal dysfunction...
- Duodenal-jejunal bypass for the treatment of type 2 diabetes in patients with body mass index of 22-34 kg/m2: a report of 2 cases
Ricardo V Cohen
Center for Surgical Treatment of Morbid Obesity, , , , Brazil
Surg Obes Relat Dis 3:195-7. 2007
- Weight loss and plasma ghrelin levels
Francesco Rubino
N Engl J Med 347:1379-81; author reply 1379-81. 2002
- A new device for sentinel node detection in laparoscopic colon resection
Didier Mutter
IRCAD/European Institute of Telesurgery, University Louis Pasteur, Strasbourg, France
JSLS 8:347-51. 2004
..The significance of nodes apparently clear but positive with the quantitative detection technique should be further evaluated...
- Transcontinental robot-assisted remote telesurgery: feasibility and potential applications
Jacques Marescaux
IRCAD EITS European Institute of Telesurgery, Louis Pasteur University, Strasbourg, France
Ann Surg 235:487-92. 2002
..To show the feasibility of performing surgery across transoceanic distances by using dedicated asynchronous transfer mode (ATM) telecommunication technology...
