Wild animal mortality monitoring and human Ebola outbreaks, Gabon and Republic of Congo, 2001-2003Pierre Rouquet
Centre International de Recherches Medicales de Franceville, CIRMF BP 769, Franceville, Gabon
Emerg Infect Dis 11:283-90. 2005
..Wild animal outbreaks began before each of the 5 human Ebola outbreaks. Twice we alerted the health authorities to an imminent risk for human outbreaks, weeks before they occurred...
- Isolates of Zaire ebolavirus from wild apes reveal genetic lineage and recombinants
Tatiana J Wittmann
Centre International de Recherches Medicales de Franceville, BP 769 Franceville, Gabon
Proc Natl Acad Sci U S A 104:17123-7. 2007
..The potential for recombination adds an additional level of complexity to unraveling and potentially controlling the emergence of ZEBOV in humans and wildlife species...
Fruit bats as reservoirs of Ebola virusEric M Leroy
Centre International de Recherches Medicales de Franceville, BP 769 Franceville, Gabon
Nature 438:575-6. 2005
..We find evidence of asymptomatic infection by Ebola virus in three species of fruit bat, indicating that these animals may be acting as a reservoir for this deadly virus...
- Multiple Ebola virus transmission events and rapid decline of central African wildlife
Eric M Leroy
Institut de Recherche pour le Developpement, UR034, Centre International de Recherches Medicales de Franceville, BP 769 Franceville, Gabon
Science 303:387-90. 2004
..Surveillance of animal mortality may help to predict and prevent human Ebola outbreaks...
Simian immunodeficiency virus types 1 and 2 (SIV mnd 1 and 2) have different pathogenic potentials in rhesus macaques upon experimental cross-species transmissionSandrine Souquiere
Laboratoire de Retrovirologie, Centre International de Recherches Médicales CIRMF, Franceville, Gabon
J Gen Virol 90:488-99. 2009
..The demonstration of the ability of both SIVmnd types to induce persistent infections in rhesus macaques calls for a careful assessment of the potential of these two viruses to emerge as new human pathogens...
- Ebola virus antibody prevalence in dogs and human risk
Loïs Allela
Centre International de Recherches Medicales de Franceville, Franceville, Gabon
Emerg Infect Dis 11:385-90. 2005
..8%. A significant positive direct association existed between seroprevalence and the distances to the Ebola virus-epidemic area. This study suggests that dogs can be infected by Ebola virus and that the putative infection is asymptomatic...
- Complete-genome analysis of hepatitis B virus from wild-born chimpanzees in central Africa demonstrates a strain-specific geographical cluster
Maria Makuwa
Centre International de Recherches Medicales de Franceville, Unité de Rétrovirologie et Centre de Primatologie, Franceville, Gabon
J Gen Virol 88:2679-85. 2007
..The strong phylogenetic associations of ChHBV sequences with both chimpanzee subspecies and their geographical origin were therefore confirmed...
- Fetal ultrasonography: biometric data from four African primate species
Olivier Bourry
Centre International de Recherches Medicales de Franceville, Franceville, Gabon
J Med Primatol 35:38-47. 2006
..Reproductive monitoring is required to improve breeding performances. Ultrasonography is a safe method to determine gestational age and to estimate the date of parturition. However only few data are available in nonhuman primates...
- High levels of SIVmnd-1 replication in chronically infected Mandrillus sphinx
Ivona Pandrea
Laboratoire de Virologie, UGENET, SEGC, , Centre de Primatologie, , BP769, Franceville, Gabon, France
Virology 317:119-27. 2003
..Similar to other nonpathogenic models of lentiviral infection, these results show a persistent high level of SIVmnd-1 replication during chronic infection of mandrills, with minimal effects on T cell subpopulations...
- Effect of human vicinity on antimicrobial resistance and integrons in animal faecal Escherichia coli
David Skurnik
, , AP-HP and EA3964, , 46 rue Henri Huchard, 75018 Paris, France
J Antimicrob Chemother 57:1215-9. 2006
..The presence of integrons may constitute an adaptive process to environments whose antimicrobial pressure exceeds a certain threshold...
- Change in salt intake affects blood pressure of chimpanzees: implications for human populations
Paul Elliott
Department of Epidemiology and Public Health, Imperial College London, Faculty of Medicine, St Mary s Campus, Norfolk Place, London W2 1PG, UK
Circulation 116:1563-8. 2007
..Effects of more modest alterations to sodium intakes in chimpanzees, akin to current efforts to lower sodium intakes in the human population, are unknown...
- Contraception in the chimpanzee: 12-year experience at the CIRMF Primate Centre, Gabon
Olivier Bourry
Centre de Primatologie, Centre International de Recherches Medicales, BP 769 Franceville, Gabon
J Med Primatol 34:25-34. 2005
..Starting in late 2000, 25 females received progestin implants; only one failure has so far occurred, and the main side effect is a complete abrogation of cyclic sexual swelling...
- Genetic immunisation by liver stage antigen 3 protects chimpanzees against malaria despite low immune responses
Pierre Daubersies
Unité de Parasitologie Biomédicale, Institut Pasteur, Paris, France
PLoS ONE 3:e2659. 2008
..The true interest of genetic immunisation might have been hastily underestimated based on overall immunogenicity data in humans and lack of parallelism with other, more classical immunisation methods...
