YVONNE J ROSENBERG

Summary

Publications

  1. doi request reprint Pharmacokinetics and immunogenicity of a recombinant human butyrylcholinesterase bioscavenger in macaques following intravenous and pulmonary delivery
    YVONNE J ROSENBERG
    PlantVax Inc, Rockville, MD 20850, USA Electronic address
    Chem Biol Interact 242:219-26. 2015
  2. doi request reprint Protection against paraoxon toxicity by an intravenous pretreatment with polyethylene-glycol-conjugated recombinant butyrylcholinesterase in macaques
    YVONNE J ROSENBERG
    PlantVax Inc, Rockville, MD 20850, United States Electronic address
    Chem Biol Interact 210:20-5. 2014
  3. pmc Rapid high-level production of functional HIV broadly neutralizing monoclonal antibodies in transient plant expression systems
    Yvonne Rosenberg
    PlantVax Corporation, Rockville, Maryland, United States of America
    PLoS ONE 8:e58724. 2013
  4. pmc Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques
    YVONNE J ROSENBERG
    PlantVax Inc, Suite 120, 9430 Key West Ave, Rockville, MD 20850 6350, USA
    Chem Biol Interact 203:167-71. 2013
  5. doi request reprint Demonstration of in vivo stability and lack of immunogenicity of a polyethyleneglycol-conjugated recombinant CHO-derived butyrylcholinesterase bioscavenger using a homologous macaque model
    YVONNE J ROSENBERG
    PlantVax Inc, Suite 120, 9430 Key West Avenue, Rockville, MD 20850 6350, USA
    Chem Biol Interact 187:279-86. 2010
  6. doi request reprint A highly stable minimally processed plant-derived recombinant acetylcholinesterase for nerve agent detection in adverse conditions
    YVONNE J ROSENBERG
    PlantVax Inc, Rockville, MD, 20850
    Sci Rep 5:13247. 2015

Detail Information

Publications6

  1. doi request reprint Pharmacokinetics and immunogenicity of a recombinant human butyrylcholinesterase bioscavenger in macaques following intravenous and pulmonary delivery
    YVONNE J ROSENBERG
    PlantVax Inc, Rockville, MD 20850, USA Electronic address
    Chem Biol Interact 242:219-26. 2015
    ..These data highlight the difficulties inherent in assessing pharmacokinetics and immunogenicity in animal models, but bode well for the efficacy and safety of rHuBChE pretreatments in homologous humans. ..
  2. doi request reprint Protection against paraoxon toxicity by an intravenous pretreatment with polyethylene-glycol-conjugated recombinant butyrylcholinesterase in macaques
    YVONNE J ROSENBERG
    PlantVax Inc, Rockville, MD 20850, United States Electronic address
    Chem Biol Interact 210:20-5. 2014
    ..v. rBChE pretreatment against a pesticide such as Px and bodes well for a parenteral rHuBChE pretreatment as an OP countermeasure in humans. ..
  3. pmc Rapid high-level production of functional HIV broadly neutralizing monoclonal antibodies in transient plant expression systems
    Yvonne Rosenberg
    PlantVax Corporation, Rockville, Maryland, United States of America
    PLoS ONE 8:e58724. 2013
    ..In addition, they warrant detailed cost-benefit analysis of prolonged incubation in plants to further increase mAb production...
  4. pmc Pulmonary delivery of an aerosolized recombinant human butyrylcholinesterase pretreatment protects against aerosolized paraoxon in macaques
    YVONNE J ROSENBERG
    PlantVax Inc, Suite 120, 9430 Key West Ave, Rockville, MD 20850 6350, USA
    Chem Biol Interact 203:167-71. 2013
    ....
  5. doi request reprint Demonstration of in vivo stability and lack of immunogenicity of a polyethyleneglycol-conjugated recombinant CHO-derived butyrylcholinesterase bioscavenger using a homologous macaque model
    YVONNE J ROSENBERG
    PlantVax Inc, Suite 120, 9430 Key West Avenue, Rockville, MD 20850 6350, USA
    Chem Biol Interact 187:279-86. 2010
    ..This homologous model can provide necessary preclinical protection data for the use of PEG-rHuBChE in humans and bodes well for a safe and efficacious CHO-derived rHuBChE therapeutic...
  6. doi request reprint A highly stable minimally processed plant-derived recombinant acetylcholinesterase for nerve agent detection in adverse conditions
    YVONNE J ROSENBERG
    PlantVax Inc, Rockville, MD, 20850
    Sci Rep 5:13247. 2015
    ....