A Covic

Summary

Affiliation: Fundeni Clinical Institute
Country: Romania

Publications

  1. ncbi request reprint The epidemics of cardiovascular disease in elderly patients with chronic kidney disease--two facets of the same problem
    Adrian Covic
    Nephrology Clinic and Dialysis and Transplantation Center, C I Parhon University Hospital, 6600, Iasi, Romania
    Int Urol Nephrol 38:371-9. 2006
  2. ncbi request reprint Hemoglobin normalization trials in chronic kidney disease: what should we learn about quality of life as an end point?
    A Covic
    Nephrology Clinic, Dr C I Parhon University Hospital, Iasi Romania
    J Nephrol 21:478-84. 2008
  3. ncbi request reprint The impact of acute kidney injury on short-term survival in an Eastern European population with stroke
    Adrian Covic
    Dialysis and Transplantation Center, Dr C I Parhon University Hospital, Iai, Romania
    Nephrol Dial Transplant 23:2228-34. 2008
  4. ncbi request reprint Analysis of safety and efficacy of pegylated-interferon alpha-2a in hepatitis C virus positive hemodialysis patients: results from a large, multicenter audit
    Adrian Covic
    Dialysis Center, Dr C I Parhon University Hospital, Iasi and The Romanian Renal Registry, Bucharest, Romania
    J Nephrol 19:794-801. 2006
  5. ncbi request reprint The influence of dialytic modality on arterial stiffness, pulse wave reflections, and vasomotor function
    Adrian Covic
    Dialysis and Transplantation, Parhon University Hospital, Iasi, Romania
    Perit Dial Int 24:365-72. 2004
  6. ncbi request reprint Current dilemmas in inhibiting the renin-angiotensin system: do not forget real life
    Adrian Covic
    Nephrology Clinic, Parhon University Hospital, Nr 50, Iasi, Romania
    Int Urol Nephrol 39:571-6. 2007
  7. ncbi request reprint Acute effect of CyA A (Neoral) on large artery hemodynamics in renal transplant patients
    Adrian Covic
    Dialysis Unit, Parhon University Hospital, Iasi, Romania
    Kidney Int 67:732-7. 2005
  8. ncbi request reprint Final Word: The binders wars 2007-2017: "The truth is out there somewhere..."
    Adrian Covic
    Nephrology Clinic, Dr C I Parhon University Hospital, Iasi, Romania
    Semin Dial 20:170-1. 2007
  9. ncbi request reprint Arterial stiffness in renal patients: an update
    Adrian Covic
    Dialysis and Renal Transplantation Center, Parhon University Hospital, Iasi, Romania
    Am J Kidney Dis 45:965-77. 2005
  10. ncbi request reprint Vascular calcification--a new window on the cardiovascular system: role of agents used to manipulate skeletal integrity
    Adrian Covic
    Nephrology Clinic, Dr C I Parhon University Hospital, Iasi, Romania
    Semin Dial 20:158-69. 2007

Collaborators

Detail Information

Publications88

  1. ncbi request reprint The epidemics of cardiovascular disease in elderly patients with chronic kidney disease--two facets of the same problem
    Adrian Covic
    Nephrology Clinic and Dialysis and Transplantation Center, C I Parhon University Hospital, 6600, Iasi, Romania
    Int Urol Nephrol 38:371-9. 2006
    ..However, elderly renal patients receive less proper cardiovascular therapy compared to non-renal subjects of the same age. This review deals briefly with the most significant data published in the last decade on CVD in elderly with CKD...
  2. ncbi request reprint Hemoglobin normalization trials in chronic kidney disease: what should we learn about quality of life as an end point?
    A Covic
    Nephrology Clinic, Dr C I Parhon University Hospital, Iasi Romania
    J Nephrol 21:478-84. 2008
    ..Finally, the authors provide recommendations on a more rigorous assessment of QoL in future trials in CKD patients...
  3. ncbi request reprint The impact of acute kidney injury on short-term survival in an Eastern European population with stroke
    Adrian Covic
    Dialysis and Transplantation Center, Dr C I Parhon University Hospital, Iai, Romania
    Nephrol Dial Transplant 23:2228-34. 2008
    ..We aimed to describe in an East European cohort (i) the incidence of AKI and its risk factors; (ii) the 30-day mortality and its risk factors and (iii) the relationship between mortality, pre-existent renal function and subsequent AKI...
  4. ncbi request reprint Analysis of safety and efficacy of pegylated-interferon alpha-2a in hepatitis C virus positive hemodialysis patients: results from a large, multicenter audit
    Adrian Covic
    Dialysis Center, Dr C I Parhon University Hospital, Iasi and The Romanian Renal Registry, Bucharest, Romania
    J Nephrol 19:794-801. 2006
    ..Pegylated interferon (PEG-IFN) is better tolerated and has a more sustained antiviral effect in the general population. There have been no large trials to date with PEG-IFN in hemodialysis populations...
  5. ncbi request reprint The influence of dialytic modality on arterial stiffness, pulse wave reflections, and vasomotor function
    Adrian Covic
    Dialysis and Transplantation, Parhon University Hospital, Iasi, Romania
    Perit Dial Int 24:365-72. 2004
    ..There is, however, a lack of information on the comparative impact of different renal replacement therapies (RRTs) on PWV and Alx, and how these different methods might influence endothelial-dependent abnormal vasodilatation...
  6. ncbi request reprint Current dilemmas in inhibiting the renin-angiotensin system: do not forget real life
    Adrian Covic
    Nephrology Clinic, Parhon University Hospital, Nr 50, Iasi, Romania
    Int Urol Nephrol 39:571-6. 2007
    ....
  7. ncbi request reprint Acute effect of CyA A (Neoral) on large artery hemodynamics in renal transplant patients
    Adrian Covic
    Dialysis Unit, Parhon University Hospital, Iasi, Romania
    Kidney Int 67:732-7. 2005
    ....
  8. ncbi request reprint Final Word: The binders wars 2007-2017: "The truth is out there somewhere..."
    Adrian Covic
    Nephrology Clinic, Dr C I Parhon University Hospital, Iasi, Romania
    Semin Dial 20:170-1. 2007
  9. ncbi request reprint Arterial stiffness in renal patients: an update
    Adrian Covic
    Dialysis and Renal Transplantation Center, Parhon University Hospital, Iasi, Romania
    Am J Kidney Dis 45:965-77. 2005
    ..Finally, the most promising novel and/or potential therapies regarding reduction of arterial stiffness in renal patients are reviewed...
  10. ncbi request reprint Vascular calcification--a new window on the cardiovascular system: role of agents used to manipulate skeletal integrity
    Adrian Covic
    Nephrology Clinic, Dr C I Parhon University Hospital, Iasi, Romania
    Semin Dial 20:158-69. 2007
  11. ncbi request reprint Biosimilars: recent developments
    A Covic
    Dialysis and Transplantation Centre, C I Parhon University Hospital, Iasi 700503, Romania
    Int Urol Nephrol 39:261-6. 2007
    ....
  12. ncbi request reprint Increased arterial stiffness in children on haemodialysis
    Adrian Covic
    Dialysis and Transplantation Center, C I Parhon University Hospital, Iasi, Romania
    Nephrol Dial Transplant 21:729-35. 2006
    ..Very few data have been reported regarding arterial stiffness in paediatric renal populations...
  13. ncbi request reprint Arterial wave reflections and mortality in haemodialysis patients--only relevant in elderly, cardiovascularly compromised?
    Adrian Covic
    Dialysis and Transplantation Center, C I Parhon University Hospital, 50 Carol 1st Blvd, Iasi, 700503 Romania
    Nephrol Dial Transplant 21:2859-66. 2006
    ....
  14. ncbi request reprint Aortic pulse wave velocity and arterial wave reflections predict the extent and severity of coronary artery disease in chronic kidney disease patients
    A Covic
    C I Parhon University Hospital, Dialysis and Transplantation Center, Iasi Romania
    J Nephrol 18:388-96. 2005
    ..We aimed to explore relationships between arterial stiffness and CAD in cohorts of patients with chronic kidney disease (CKD)...
  15. ncbi request reprint Epidemiology of renal disease in Romania: a 10 year review of two regional renal biopsy databases
    Adrian Covic
    Dialysis and Transplantation Center, C I Parhon University Hospital, Iasi, Romania
    Nephrol Dial Transplant 21:419-24. 2006
    ..This report is the first review of histological data, over a period of 10 years (1995-2004), covering a population of over 6 million inhabitants and two distinct regions from an East European country - Romania...
  16. ncbi request reprint Serial echocardiographic changes in patients on hemodialysis: an evaluation of guideline implementation
    Adrian Covic
    Dialysis and Transplantation Center, Dr C I Parhon University Hospital, Iasi, Romania
    J Nephrol 19:783-93. 2006
    ....
  17. ncbi request reprint Illness representations and quality of life scores in haemodialysis patients
    Adrian Covic
    Dialysis and Transplantation Center, C I Parhon Hospital, 50 Carol 1st Blvd, Iasi 6600, Romania
    Nephrol Dial Transplant 19:2078-83. 2004
    ..In this cross-sectional study we examined the impact of illness representations on QoL of HD patients and the influence of HD duration on this relationship...
  18. doi request reprint Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of all-cause mortality, cardiovascular mortality and cardiovascular events in chronic kidney disease
    Adrian Covic
    Dialysis and Renal Transplantation Center, C I Parhon University Hospital and University of Medicine Gr T Popa Iasi, Blvd Carol I Nr 50, Iasi, 700503, Romania
    Nephrol Dial Transplant 24:1506-23. 2009
    ..Thus, a systematic review was conducted to assess methodological and clinical heterogeneity by comparing designs, analytical approaches and results of studies...
  19. pmc The safety and efficacy of intravenous ferric carboxymaltose in anaemic patients undergoing haemodialysis: a multi-centre, open-label, clinical study
    Adrian Covic
    Dialysis and Transplantation Center, Parhon University Hospital, Lasi, Romania
    Nephrol Dial Transplant 25:2722-30. 2010
    ..This study primarily investigated the safety, and also the efficacy, of ferric carboxymaltose (FCM), a next-generation i.v. iron formulation, given as a bolus-push injection in patients with CKD undergoing maintenance haemodialysis (HD)...
  20. ncbi request reprint A retrospective 5-year study in Moldova of acute renal failure due to leptospirosis: 58 cases and a review of the literature
    Adrian Covic
    Dialysis and Transplantation Center, C I Parhon University Hospital, Iasi, Romania
    Nephrol Dial Transplant 18:1128-34. 2003
    ..Few large series describe in detail clinical and laboratory features of cases with ARF and their outcome...
  21. ncbi request reprint Successful renal transplantation decreases aortic stiffness and increases vascular reactivity in dialysis patients
    A Covic
    C I Parhon University Hospital, Dialysis and Transplantation Center, Iasi, Romania
    Transplantation 76:1573-7. 2003
    ..It is not known how these parameters interfere with successful renal transplantation...
  22. ncbi request reprint Haemodialysis increases QT(c) interval but not QT(c) dispersion in ESRD patients without manifest cardiac disease
    Adrian Covic
    C I Parhon Hospital, Iasi, Romania, and Guy s Hospital, London, UK
    Nephrol Dial Transplant 17:2170-7. 2002
    ..However, most studies have included end-stage renal disease (ESRD) patients with significant heart pathology. We therefore aimed to study the impact of a single HD session in subjects without manifest cardiac disease...
  23. ncbi request reprint Ambulatory blood pressure monitoring in renal transplantation: should ABPM be routinely performed in renal transplant patients?
    Adrian Covic
    C I Parhon University Hospital, Dialysis and Transplantation Center, Iasi, Romania
    Transplantation 76:1640-2. 2003
    ....
  24. pmc Trace elements in end-stage renal disease--unfamiliar territory to be revealed
    Adrian Covic
    Nephrology Clinic, Parhon University Hospital, GR, T, Popa University of Medicine and Pharmacy, Iasi, Romania
    BMC Nephrol 10:12. 2009
    ....
  25. ncbi request reprint The challenge of cardiovascular risk factors in end-stage renal disease
    Adrian Covic
    Dialysis and Renal Transplantation Center, Parhon University Hospital, Iasi, Romania
    J Nephrol 16:476-86. 2003
    ..Efficient dialysis, ACE-inhibitors and beta-blockers, statins, antiplatelet treatment and adequate control of calcium-phosphorus metabolism should be the mainstay of therapy in the ESRD patients with several CV risk factors...
  26. ncbi request reprint Haemodialysis acutely improves endothelium-independent vasomotor function without significantly influencing the endothelium-mediated abnormal response to a beta 2-agonist
    Adrian Covic
    Dialysis and Transplantation Center, C I Parhon University Hospital, Iasi, Romania
    Nephrol Dial Transplant 19:637-43. 2004
    ....
  27. ncbi request reprint Successful use of Molecular Absorbent Regenerating System (MARS) dialysis for the treatment of fulminant hepatic failure in children accidentally poisoned by toxic mushroom ingestion
    Adrian Covic
    Dialysis Center, University Hospital, Iasi, Romania
    Liver Int 23:21-7. 2003
    ..MARS is a new, cell-free, extracorporeal liver assistance method utilizing an albumin dialysate for the removal of albumin-bound toxins...
  28. ncbi request reprint Diabetes, kidney disease and anaemia: time to tackle a troublesome triad?
    S Al-Khoury
    Department of Nephrology and Transplantation, Guy s Hospital, London, UK
    Int J Clin Pract 61:281-9. 2007
    ..In addition, recent publications from large-scale epidemiological studies have highlighted the impact of anaemia on diabetic patients. The purpose of this review was to focus on the pathophysiology and impact of anaemia in DM...
  29. ncbi request reprint What added value does ambulatory blood pressure monitoring brings to the management of post renal transplantation hypertension?
    A Covic
    Dialysis Center, C I Parhon University Hospital, Iasi
    Rev Med Chir Soc Med Nat Iasi 107:89-97. 2003
    ..To evaluate BP control, white coat hypertension (WCH) and abnormal circadian variability in a significant outpatient sample of renal transplant (RTx) subjects, normotensive at the last regular visit...
  30. ncbi request reprint Causes and consequences of increased arterial stiffness in chronic kidney disease patients
    Paul Gusbeth-Tatomir
    Dialysis and Renal Transplantation Center, Parhon University Hospital, Iasi, Romania
    Kidney Blood Press Res 30:97-107. 2007
    ..The potential therapeutic interventions - mainly the use of certain antihypertensive drugs and reduction of vascular calcification - are finally discussed...
  31. ncbi request reprint Anaemia in diabetic patients with chronic kidney disease--prevalence and predictors
    S Al-Khoury
    Department of Renal Medicine, Guy s and St Thomas Hospitals, London, UK
    Diabetologia 49:1183-9. 2006
    ..We investigated the relationship between haemoglobin (Hb) and diabetes in patients with renal disease...
  32. ncbi request reprint The reproducibility of the circadian BP rhythm in treated hypertensive patients with polycystic kidney disease and mild chronic renal impairment--a prospective ABPM study
    Adrian Covic
    Renal Unit, Parhon Hospital, Iasi, Romania
    J Nephrol 15:497-506. 2002
    ..It is not known whether the same is true for patients with renal disease...
  33. ncbi request reprint Long-hours home haemodialysis--the best renal replacement therapy method?
    A Covic
    Renal Unit, Parhon Hospital, Iasi, Romania
    QJM 92:251-60. 1999
    ..Our data show a low incidence of all-cause and cardiovascular mortality, confirming those from the Tassin unit in France, and make a medical case for extended haemodialysis treatment hours...
  34. ncbi request reprint Hepatitis virus infection in haemodialysis patients from Moldavia
    A Covic
    IV Medical Clinic, Nephrology, C I Parhon Hospital, Iasi, Romania
    Nephrol Dial Transplant 14:40-5. 1999
    ....
  35. ncbi request reprint Dynamics of the circadian blood pressure profiles after renal transplantation
    Adrian Covic
    Dialysis and Transplantation Center, C I Parhon University Hospital, Iasi, Romania acovicxnet ro
    Transplantation 80:1168-73. 2005
    ..To date, no study has attempted to define and model the evolution of diurnal BP rhythm profiles from dialysis to engraftment, focusing on the immediate (4-6 weeks) and medium-term (>1 year) postengraftment periods...
  36. ncbi request reprint Ambulatory blood pressure monitoring in hemodialysis patients: a critique and literature review
    Adrian Covic
    Renal Unit, Parhon Hospital, Iasi, Romania
    Semin Dial 17:255-9. 2004
    ..Use of ABP monitoring can go some way to overcoming these obstacles. In this review we critically examine the use of ABP monitoring in the understanding of blood pressure control in dialysis patients...
  37. ncbi request reprint Cardiac troponins in renal failure - time for an optimistic consensus?
    I Buhaescu
    Dialysis and Renal Transplantation Center, Parhon University Hospital, Iasi, Romania
    Int J Clin Pract 59:1317-25. 2005
    ....
  38. ncbi request reprint Ambulatory blood pressure monitoring: an essential tool for blood pressure assessment in uraemic patients
    Adrian Covic
    Renal Unit, Parhon Hospital, Iasi, Romania
    Nephrol Dial Transplant 17:1737-41. 2002
  39. ncbi request reprint Coronary artery calcification and aortic pulse wave velocity in chronic kidney disease patients
    Ali A Haydar
    Renal and Transplantation Unit, Guy s Hospital, London, UK
    Kidney Int 65:1790-4. 2004
    ..The aim of our study was to explore the relationship between measures of arterial stiffness-pulse wave velocity (PWV)-and the extent of calcification in the coronary arteries (CAC)...
  40. ncbi request reprint Systolic blood pressure diurnal variation is not a predictor of renal target organ damage in kidney transplant recipients
    Ali A Haydar
    Renal and Transplantation Unit, Guy s Hospital, London, UK
    Am J Transplant 4:244-7. 2004
    ..Only early kidney function was an independent predictor of later serum creatinine...
  41. ncbi request reprint Arrhythmias in hemodialysis patients
    Luminita Voroneanu
    Nephrology Clinic and Dialysis Center, Parhon University Hospital, Gr T Popa University of Medicine and Pharmacy, Iasi, Romania
    J Nephrol 22:716-25. 2009
    ....
  42. ncbi request reprint A clinical description of rifampicin-induced acute renal failure in 170 consecutive cases
    A Covic
    CI Parhon Hospital, Iasi, Romania
    J Indian Med Assoc 102:20, 22-5. 2004
    ..The mortality rate was 3.5%, compared to 21% for the overall ARF population treated during the same period (p < 0.05)...
  43. ncbi request reprint Surgical management of renal hyperparathyroidism: a preliminary series report
    M R Diaconescu
    IVth Surgical Clinic, Gr T Popa University of Medicine and Pharmacy, Iasi, Romania
    Chirurgia (Bucur) 106:51-7. 2011
    ..Renal hyperparathyroidism (RHPT) is a frequent complication of uremic patients on hemodialysis and despite various advances in medical therapy parathyroidectomy is necessary in a semnificative number of cases...
  44. doi request reprint Factors affecting the quality of life of haemodialysis patients from Romania: a multicentric study
    Anca Seica
    Nephrocare Dialysis Center, Iasi, Romania
    Nephrol Dial Transplant 24:626-9. 2009
    ..Therefore, QoL needs to be regularly assessed in this setting. Our study describes QoL, as well as demographic and clinical variables associated with QoL in chronic haemodialysis (HD) patients in Romania...
  45. ncbi request reprint Anemia after renal transplantation
    Behdad Afzali
    Department of Nephrology and Transplantation, Guy s Hospital, London, UK
    Am J Kidney Dis 48:519-36. 2006
    ....
  46. ncbi request reprint Sleep disorders: a systematic review of an emerging major clinical issue in renal patients
    Paul Gusbeth-Tatomir
    Dialysis and Renal Transplant Center, Dr C I Parhon University Hospital, Gr T Popa University of Medicine and Pharmacy, Carol 1st Blvd Nr 50, 700503, Iasi, Romania
    Int Urol Nephrol 39:1217-26. 2007
    ..Here, we review recent data on sleep disturbances in renal patients, focusing on the end-stage renal disease patient treated by dialysis...
  47. doi request reprint Direct renin inhibitors: ONTARGET for success?
    Yasmin Pasha
    Chelsea and Westminster Hospital, Fulham Road, London, UK
    Int Urol Nephrol 41:341-55. 2009
    ....
  48. ncbi request reprint Nephrology and renal replacement therapy in Romania--transition still continues (Cinderella story revisited)
    Gabriel Mircescu
    Dr Carol Davila University Hospital of Nephrology, Bucharest, Romania
    Nephrol Dial Transplant 19:2971-80. 2004
    ..INTRODUCTION. This report describes the current status of nephrology and renal replacement therapy (RRT) in Romania, a country with previously limited facilities, highlighting national changes in the European context...
  49. ncbi request reprint Cardiovascular disease in renal allograft recipients is associated with elevated sialic acid or markers of inflammation
    Rashed S Bakri
    Nephrology and Transplantation, Guy s Hospital, London, UK
    Clin Transplant 18:201-4. 2004
    ..Cardiovascular disease (CVD) is more common in patients with renal failure, even after renal transplantation. We wished to examine the relationship between markers of inflammation and CVD in stable renal transplant patients...
  50. ncbi request reprint What is the role of ambulatory BP monitoring in pediatric nephrology?
    Cristina Gavrilovici
    Renal Pediatric Department, St Marry Childrens Hospital, Iasi, Romania
    J Nephrol 17:642-52. 2004
    ..ABPM offers some clear solutions to these problems and thus should be routinely used in appropriately defined clinical settings, but is not a panacea...
  51. ncbi request reprint The success story of peritoneal dialysis in Romania: analysis of differences in mortality by dialysis modality and influence of risk factors in a national cohort
    Gabriel Mircescu
    Dr Carol Davila Teaching Hospital of Nephrology, Bucharest, Romania
    Perit Dial Int 26:266-75. 2006
    ....
  52. ncbi request reprint New markers and therapies for coronary artery disease in renal patients
    J Smyth
    Renal Unit, Guy s Hospital, London, UK
    Minerva Urol Nefrol 54:157-62. 2002
    ..There is a real need for additional and complementary markers of coronary disease in these patients. We discuss some novel ideas for screening and for intervention in this most challenging clinical setting...
  53. ncbi request reprint Burden of disease - prevalence and incidence of ESRD in selected European regions and populations
    A Covic
    Parhon Hospital, University Gr T Popa, Iasi, Romania
    Clin Nephrol 74:S23-7. 2010
    ..Regarding mineral metabolism, the percent of patients achieving all four parameters (Ca, P, CaxP and PTH) was also higher in Western Europe. The adherence to EBPG (European Best Practice Guidelines) was also higher in these countries...
  54. doi request reprint Systematic review of the evidence underlying the association between mineral metabolism disturbances and risk of fracture and need for parathyroidectomy in CKD
    David Goldsmith
    Guy s Hospital, London, UK
    Am J Kidney Dis 53:1002-13. 2009
    ..Thus, a systematic review was conducted to assess method or clinical heterogeneity by comparing the design, analytical techniques, and results of studies...
  55. doi request reprint Vascular calcification in chronic kidney disease
    Adrian Covic
    Clinic of Nephrology, C I Parhon University Hospital, Gr T Popa University of Medicine and Pharmacy, Bd Carol I, Nr 50, Iasi, Romania
    Clin Sci (Lond) 119:111-21. 2010
    ....
  56. ncbi request reprint Antihypertensive treatment and stroke prevention in patients with and without chronic kidney disease: a review of controlled trials
    Liviu Segall
    Nephrology, Dialysis and Renal Transplantation Center, C I Parhon University Hospital, Iasi, Romania
    J Nephrol 21:374-83. 2008
    ..However, the optimal stroke prevention strategy in these patients is unclear, because controlled studies are scarce...
  57. doi request reprint Diagnosis of tuberculosis in dialysis patients: current strategy
    Liviu Segall
    Nephrology Department, Dr C I Parhon Hospital, University of Medicine and Pharmacy Gr T Popa, Iasi, Romania
    Clin J Am Soc Nephrol 5:1114-22. 2010
    ..Therefore, current strategy in dialysis patients should use these tests instead of TST for LTBI screening and as an aid for the diagnosis of active TB...
  58. ncbi request reprint Intradialytic changes in reflective properties of the arterial system during a single hemodialysis session
    Nicoleta Genoveva Mardare
    Dialysis and Transplantation Center, C I Parhon University Hospital, Iasi, Romania
    Hemodial Int 9:376-82. 2005
    ..The effect is not explained by the UFV depletion but is highly correlated with the decrease in SBP and PP. Further work is now needed to explore a potential role for endothelin and nitric oxide metabolism...
  59. ncbi request reprint Acute liver failure due to leptospirosis successfully treated with MARS (molecular adsorbent recirculating system) dialysis
    Adrian Covic
    Dialysis Center, Dr C I Parhon University Hospital, Iasi, Romania
    Int Urol Nephrol 39:313-6. 2007
    ..Leptospirosis is a re-emerging infectious disease, which may lead to multiple organ failure (MOF)and death...
  60. ncbi request reprint Sirolimus--challenging current perspectives
    Irina Buhaescu
    Dialysis and Renal Transplantation Center, Parhon University Hospital, Iasi, Romania
    Ther Drug Monit 28:577-84. 2006
    ..A brief description of the current knowledge of sirolimus therapeutic drug monitoring, methods of analysis, pharmacokinetics and drug interactions with calcineurin inhibitors is also included...
  61. ncbi request reprint Methods for estimating "dry weight" in hemodialysis patients
    M Onofriescu
    Gr T Popa University of Medicine and Pharmacy, Iasi, Romania
    Rev Med Chir Soc Med Nat Iasi 115:742-9. 2011
    ....
  62. ncbi request reprint Systemic vasculitis: still a challenging disease
    Irina Buhaescu
    Dialysis and Renal Transplantation Center, Parhon University Hospital, Iasi, Romania
    Am J Kidney Dis 46:173-85. 2005
    ....
  63. ncbi request reprint New immunosuppressive therapies in renal transplantation: monoclonal antibodies
    Irina Buhaescu
    Dialysis and Renal Transplantation Center, Parhon University Hospital, Iasi Romania
    J Nephrol 18:529-36. 2005
    ..Blocking either the binding of cell-surface molecules or intracellular signal transduction, these mAbs could become an effective method to promote the holy grail of solid-organ transplantation, antigen-specific tolerance...
  64. doi request reprint Methods and potential biomarkers for the evaluation of endothelial dysfunction in chronic kidney disease: a critical approach
    Simona M Hogas
    Nephrology Clinic at C I Parhon University Hospital, Gr T Popa University of Medicine and Pharmacy, Iasi, Romania
    J Am Soc Hypertens 4:116-27. 2010
    ..Therefore, a combined biomarker and bedside investigational approach could be a starting point for developing optimal therapeutic tools...
  65. ncbi request reprint Recent insights from studies using ambulatory blood pressure monitoring in patients with renal disease
    Adrian Covic
    Dialysis and Transplant Unit, Parhon Hospital, Iasi, Romania
    Curr Opin Nephrol Hypertens 12:645-8. 2003
    ..To identify and evaluate recent (2000-2003) published studies employing ambulatory blood pressure monitoring in patients with chronic renal failure, on dialysis, and after renal transplantation...
  66. ncbi request reprint Anaemia after renal transplantation--role of immunosuppressive drugs and a pathophysiological appraisal
    David Goldsmith
    Department of Nephrology and Transplantation, Guy s Hospital, London, UK
    Nephron Clin Pract 104:c69-74. 2006
    ..It is the purpose of this article to briefly review the contribution from transplant immunosuppression to PTA and to assess its likely effects on and treatment options for patients...
  67. doi request reprint The role of the renin-angiotensin-aldosterone system in renal artery stenosis, renovascular hypertension, and ischemic nephropathy: diagnostic implications
    Adrian Covic
    Nephrology Clinic, Parhon University Hospital, Gr T Popa University of Medicine and Pharmacy, Carol 1st Boulevard, Iasi, Romania
    Prog Cardiovasc Dis 52:204-8. 2009
    ..Unfortunately, this issue still remains a major challenge for nephrologists...
  68. ncbi request reprint Renal corpuscle morphometry with increased reliability and high level of automation
    Irina Draga Caruntu
    Department of Histology, Gr T Popa University of Medicine and Pharmacy, Iasi, Iasi, Romania
    Pathol Res Pract 203:9-20. 2007
    ..This may contribute to a better understanding of the RPGN evolution and, implicitly, to the refinement of the diagnosis...
  69. ncbi request reprint Through the looking glass: the protein science of biosimilars
    David Goldsmith
    Renal Unit, New Guy House, Guy s Hospital, London, UK
    Clin Exp Nephrol 11:191-5. 2007
    ..This review takes a look at how biosimilars are fundamentally different from their originator products by examining the biopharmaceutical production process and how it can influence the structure and function of the final drug product...
  70. ncbi request reprint How important and how treatable is vascular stiffness as a cardiovascular risk factor in renal failure?
    David Goldsmith
    Nephrol Dial Transplant 17:965-9. 2002
  71. ncbi request reprint Mineral and bone disorder after renal transplantation: a review
    Hazim Sadideen
    Department of Nephrology and Transplantation, New Guy s House, Guy s Hospital, St Thomas Street, London SE1 9RT, UK
    Int Urol Nephrol 40:171-84. 2008
    ....
  72. ncbi request reprint Posttransplantation anemia in adult renal allograft recipients: prevalence and predictors
    Nilesh Shah
    Department of Renal Medicine and Transplantation, Guy s Hospital, London, United Kingdom
    Transplantation 81:1112-8. 2006
    ..The purpose of this study was to investigate a large posttransplant population from 3 centres in the UK to elucidate the point prevalence of PTA, its determinants and the use of erythropoiesis stimulating agents (ESA) in these patients...
  73. ncbi request reprint Cardiovascular disease in haemodialysis and peritoneal dialysis: arguments pro haemodialysis
    Liviu Segall
    Clinica a IV a Medicală Nefrologie, Spital Dr C I Parhon, B dul Carol I nr 50, Iasi 700503, Romania
    Nephrol Dial Transplant 22:59-63. 2007
  74. ncbi request reprint Post-transplantation anaemia in adult and paediatric renal allograft recipients-Guy's Hospital experience
    Salam Al-Khoury
    Adult Unit, Guy s Hospital, London SE1 9RT, UK
    Nephrol Dial Transplant 21:1974-80. 2006
    ....
  75. ncbi request reprint Ambulatory blood pressure measurement in the renal patient
    Adrian Covic
    Parhon Hospital, Bd Copou 50, Iasi 6600, Romania acovic xnet ro
    Curr Hypertens Rep 4:369-76. 2002
    ..Much more work is needed to dissect out the causes for abnormal diurnal blood pressure rhythm and attempt to modulate this parameter. Obstructive sleep apnea may be a promising target for intervention...
  76. ncbi request reprint Hypertension and cardiovascular risk assessment in dialysis patients
    Francesco Locatelli
    Department of Nephrology and Dialysis, Azienda Ospedale di Lecco, Ospedale A Manzoni, Italy
    Nephrol Dial Transplant 19:1058-68. 2004
    ..Hypertension in patients affected by chronic renal insufficiency (CRI) has been recognized as one of the major classical CV risk factors in CRI from the very beginning of the dialysis era. However, its treatment is still unsatisfactory...
  77. ncbi request reprint ORAMA: a study to investigate EBPG impact on renal anaemia - design and baseline data
    F Locatelli
    Department of Nephrology and Dialysis, A Manzoni Hospital, Lecco Italy
    J Nephrol 21:592-603. 2008
    ..The Optimal Renal Anaemia Management Assessment (ORAMA) is the first European study investigating the impact of adherence to the 2004 revised European Best Practice Guidelines (EBPG) and its impact on patient outcomes...
  78. ncbi request reprint Effect of treatment of hyperuricemia with allopurinol on blood pressure, creatinine clearence, and proteinuria in patients with normal renal functions
    Mehmet Kanbay
    35 Sokak, 81 5, Bahcelievler, Ankara, 06490, Turkey
    Int Urol Nephrol 39:1227-33. 2007
    ..We therefore conducted a prospective study to investigate the benefits of allopurinol treatment in hyperuricemic patients with normal renal function...
  79. ncbi request reprint Relation between serum calcium, phosphate, parathyroid hormone and 'nondipper' circadian blood pressure variability profile in patients with normal renal function
    Mehmet Kanbay
    Department of Internal Medicine, Section of Nephrology, Fatih University Faculty of Medicine, Ankara, Turkey
    Am J Nephrol 27:516-21. 2007
    ....
  80. ncbi request reprint Vascular calcification: a stiff challenge for the nephrologist: does preventing bone disease cause arterial disease?
    David Goldsmith
    Guy s Hospital, London, United Kingdom
    Kidney Int 66:1315-33. 2004
    ....
  81. ncbi request reprint Relation between serum thyroid hormone and 'nondipper' circadian blood pressure variability
    Mehmet Kanbay
    Department of Internal Medicine, Section of Nephrology, Fatih University School of Medicine, Ankara, Turkey or
    Kidney Blood Press Res 30:416-20. 2007
    ..Further studies are warranted to confirm this relationship and to elucidate the pathogenetic mechanisms of this relationship...
  82. ncbi request reprint Insights from ambulatory blood pressure monitoring: diagnosis of hypertension and diurnal blood pressure in renal transplant recipients
    Ali A Haydar
    Renal and Transplantation Unit, Guy s Hospital, London, United Kingdom
    Transplantation 77:849-53. 2004
    ....
  83. doi request reprint Renal anemia: comparing current Eastern and Western European management practice (ORAMA)
    Andrzej Wiecek
    Department of Nephrology, Endocrinology and Metabolic Diseases, Medical University of Silesia, Katowice, Francuska, Poland
    Ren Fail 30:267-76. 2008
    ..Anemia management in patients with chronic kidney disease shows considerable regional differences across Europe, and target attainment remains suboptimal in many European nephrology centers after the revised 2004 guidelines...
  84. doi request reprint European best practice quo vadis? From European Best Practice Guidelines (EBPG) to European Renal Best Practice (ERBP)
    Carmine Zoccali
    Nephrol Dial Transplant 23:2162-6. 2008
    ..The present publication reviews the arguments based on which this decision was taken...
  85. ncbi request reprint Current management of secondary hyperparathyroidism: a multicenter observational study (COSMOS)
    Jorge B Cannata-Andia
    Servicio de Metabolismo Oseo y Mineral, Instituto Reina Sofia de Investigacion, Hospital Universitario Central de Asturias, Oveido, Spain
    J Nephrol 21:290-8. 2008
    ..Second, to evaluate the additional value of albumin and hemoglobin levels in conjunction with bone mineral markers in the prediction of mortality and clinical events...
  86. ncbi request reprint Optimal composition of the dialysate, with emphasis on its influence on blood pressure
    Francesco Locatelli
    Department of Nephrology and Dialysis, Ospedale A Manzoni, Via Dell Eremo 11, 23900 Lecco, Italy
    Nephrol Dial Transplant 19:785-96. 2004
    ..Introduction. From the beginning of the dialysis era, the most appropriate composition of the dialysate has been one of the central topics in the delivery of dialysis treatment...
  87. ncbi request reprint [Risk of sudden death in patients with chronic renal failure and hemodialysis]
    Larisa Panaghiu
    Spitalul Clinic Dr C I Parhon Iaşi, Clinica a IV a Medicală Nefrologie, Universitatea de Medicină si Farmacie Gr T Popa Iaşi
    Rev Med Chir Soc Med Nat Iasi 108:290-5. 2004
    ..50% of our patients have 2 to 4 risk factors for sudden death, which increase incidence of sudden death in patients on HD...
  88. ncbi request reprint Negative outcome studies in end-stage renal disease: how dark are the storm clouds?
    Adrian Covic
    Nephrol Dial Transplant 23:56-61. 2008