Taste, olfactory and food texture reward processing in the brain and the control of appetiteEdmund T Rolls
Department of Computer Science, Oxford Centre for Computational Neuroscience, Oxford CV4 7AL, UK
Proc Nutr Soc 71:488-501. 2012
..It is proposed that control of all rather than one or several of these factors that influence food reward and eating may be important in the prevention and treatment of overeating and obesity...
- Communication before coherence
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK
Eur J Neurosci 36:2689-709. 2012
..Similar results were found when the second network was not an attractor decision-making network. Thus information transmission can occur before synapses have been made sufficiently strong to produce coherence...
- Cortical attractor network dynamics with diluted connectivity
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK
Brain Res 1434:212-25. 2012
..This article is part of a Special Issue entitled "Neural Coding"...
- Mechanisms for sensing fat in food in the mouth: Presented at the Symposium "The Taste for Fat: New Discoveries on the Role of Fat in Sensory Perception, Metabolism, Sensory Pleasure and Beyond" held at the Institute of Food Technologists 2011 A
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK
J Food Sci 77:S140-2. 2012
..These findings have implications for the design of foods that mimic the pleasant texture of fat in the mouth but have low energy content, and thus for the prevention and treatment of obesity...
- Glutamate, obsessive-compulsive disorder, schizophrenia, and the stability of cortical attractor neuronal networks
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK
Pharmacol Biochem Behav 100:736-51. 2012
....
- Taste, olfactory and food texture reward processing in the brain and obesity
E T Rolls
Oxford Centre for Computational Neuroscience, Oxford, Oxon, UK
Int J Obes (Lond) 35:550-61. 2011
..It is proposed that control of all rather than one or several of these factors that influence food reward and eating may be important in the prevention and treatment of overeating and obesity...
- An attractor hypothesis of obsessive-compulsive disorder
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK
Eur J Neurosci 28:782-93. 2008
....
Face processing in different brain areas, and critical band maskingEdmund T Rolls
Department of Experimental Psychology, University of Oxford, Oxford, UK
J Neuropsychol 2:325-60. 2008
....
- The affective and cognitive processing of touch, oral texture, and temperature in the brain
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, England, UK
Neurosci Biobehav Rev 34:237-45. 2010
..The cognitive labels also influence activations to the sight of touch and also the correlations with pleasantness in the pregenual cingulate/orbitofrontal cortex and ventral striatum...
- Warm pleasant feelings in the brain
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, England, UK
Neuroimage 41:1504-13. 2008
..This conclusion appears to be the case for processing in a number of sensory modalities, and the finding with such prototypical stimuli as warm and cold provides strong support for this principle...
- Choice, difficulty, and confidence in the brain
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, England
Neuroimage 53:694-706. 2010
..This provides a unifying and fundamental approach to decision-making and decision confidence, and to how spiking-related noise in the brain affects choice, confidence, synaptic and neuronal activity, and fMRI signals...
- Functional neuroimaging of umami taste: what makes umami pleasant?
Edmund T Rolls
Oxford Centre for Computational Neuroscience, United Kingdom
Am J Clin Nutr 90:804S-813S. 2009
..Cognitive and attentional modulation of the orbitofrontal cortex also contributes to the pleasantness and appetitive value of umami...
- Decision-making, errors, and confidence in the brain
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK
J Neurophysiol 104:2359-74. 2010
..This provides a unifying approach to decision-making and decision confidence and to how spiking-related noise affects choice, confidence, synaptic and neuronal activity, and fMRI signals...
- Prediction of subjective affective state from brain activations
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, United Kingdom
J Neurophysiol 101:1294-308. 2009
..8 million neurons or their synaptic inputs and is not part of the information encoding used by the brain, thus providing a relatively poor readout of information compared with that available from small populations of neurons...
- Computational models of schizophrenia and dopamine modulation in the prefrontal cortex
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK
Nat Rev Neurosci 9:696-709. 2008
....
- Spatial scene representations formed by self-organizing learning in a hippocampal extension of the ventral visual system
Edmund T Rolls
Department of Experimental Psychology, Centre for Computational Neuroscience, Oxford University, Oxford, UK
Eur J Neurosci 28:2116-27. 2008
..This reduced size and asymmetry of the receptive fields of inferior temporal cortex neurons also provides a solution to the representation of multiple objects, and their relative spatial positions, in complex natural scenes...
- The orbitofrontal cortex and beyond: from affect to decision-making
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, England, United Kingdom
Prog Neurobiol 86:216-44. 2008
..For this decision-making, the orbitofrontal cortex provides a representation of each specific reward in a common currency...
- Neural systems underlying decisions about affective odors
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK via e mail
J Cogn Neurosci 22:1069-82. 2010
..In contrast, areas such as medial area 10 and the ACC are implicated in reaching a decision in which a binary outcome is produced...
- A computational neuroscience approach to schizophrenia and its onset
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, UK
Neurosci Biobehav Rev 35:1644-53. 2011
....
- A computational theory of episodic memory formation in the hippocampus
Edmund T Rolls
Oxford Centre for Computational Neuroscience, Oxford, United Kingdom
Behav Brain Res 215:180-96. 2010
..Tests of the theory including hippocampal subregion analyses and hippocampal NMDA receptor knockouts are described and support the theory...
- From affective value to decision-making in the prefrontal cortex
Fabian Grabenhorst
Department of Experimental Psychology, University of Oxford, Oxford, UK
Eur J Neurosci 28:1930-9. 2008
..When a decision was yes vs. no, effects were found in the dorsal cingulate cortex, agranular (anterior) insula and ventral tegmental area, implicating these areas in initiating actions to obtain goals...
- Object, space, and object-space representations in the primate hippocampus
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
J Neurophysiol 94:833-44. 2005
....
- Object perception in natural scenes: encoding by inferior temporal cortex simultaneously recorded neurons
Nikolaos C Aggelopoulos
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, United Kingdom
J Neurophysiol 93:1342-57. 2005
..Furthermore, it was shown that there was little redundancy (6%) between the information provided by the spike counts of the simultaneously recorded neurons, making spike counts an efficient population code with a high encoding capacity...
- How the brain represents the reward value of fat in the mouth
Fabian Grabenhorst
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, UK
Cereb Cortex 20:1082-91. 2010
..This discovery of which brain regions track the subjective hedonic experience of fat texture will help to unravel possible differences in the neural responses in obese versus lean people to oral fat, a driver of food intake...
- Neuronal representations of stimuli in the mouth: the primate insular taste cortex, orbitofrontal cortex and amygdala
Mikiko Kadohisa
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Chem Senses 30:401-19. 2005
..Human psychophysics showed that the sensory spaces revealed by multidimensional scaling were similar to those provided by the neurons...
- Information in the first spike, the order of spikes, and the number of spikes provided by neurons in the inferior temporal visual cortex
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Vision Res 46:4193-205. 2006
..Thus information transmission in the inferior temporal cortex by the number of spikes in even short time windows is fast, and provides more information than only the first spike, or the spike order from different neurons...
- Taste and related systems in primates including humans
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Chem Senses 30:i76-7. 2005
- Selective attention to affective value alters how the brain processes taste stimuli
Fabian Grabenhorst
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Eur J Neurosci 27:723-9. 2008
..more sensory-related processing, may be an important aspect of cognition and attention. This has many implications for understanding the effects not only of taste but also of other sensory stimuli...
- Selective attention to affective value alters how the brain processes olfactory stimuli
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, UK
J Cogn Neurosci 20:1815-26. 2008
..This has many implications for understanding the effects not only of olfactory but also of other sensory stimuli...
- Taste-related activity in the human dorsolateral prefrontal cortex
Morten L Kringelbach
Department of Experimental Psychology, University of Oxford, and FMRIB, Oxford Centre for Functional Magnetic Resonance Imaging, John Radcliffe Hospital, UK
Neuroimage 21:781-8. 2004
..This may reflect an effect of taste on cognitive processing to help optimise or modify behavioural strategies involved in executive control; or it could reflect the engagement of this region in attentional processing by a taste input...
- Representations of the texture of food in the primate orbitofrontal cortex: neurons responding to viscosity, grittiness, and capsaicin
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
J Neurophysiol 90:3711-24. 2003
....
- Decision time, slow inhibition, and theta rhythm
Anteo Smerieri
Department of Physics, Universita di Parma, 43100 Parma, Italy, Oxford Centre for Computational Neuroscience, Oxford OX1 2UD, United Kingdom
J Neurosci 30:14173-81. 2010
....
- Cognitive modulation of olfactory processing
Ivan E de Araujo
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, United Kingdom
Neuron 46:671-9. 2005
..This cognitive modulation was also found for the test odor (but not for the clean air) in the amygdala bilaterally...
- Taste-olfactory convergence, and the representation of the pleasantness of flavour, in the human brain
Ivan E T de Araujo
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Eur J Neurosci 18:2059-68. 2003
..These results provide evidence on the neural substrate for the convergence of taste and olfactory stimuli to produce flavour in humans, and where the pleasantness of flavour is represented in the human brain...
- Face-selective and auditory neurons in the primate orbitofrontal cortex
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, England
Exp Brain Res 170:74-87. 2006
..The findings are relevant to understanding the functions of the primate including human orbitofrontal cortex in normal behaviour, and to understanding the effects of damage to this region in humans...
- Smell, taste, texture, and temperature multimodal representations in the brain, and their relevance to the control of appetite
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, Oxford, England
Nutr Rev 62:S193-204; discussion S224-41. 2004
..Much of the fundamental evidence comes from studies in non-human primates, and this is being complemented by functional neuroimaging studies in humans...
- Enhanced affective brain representations of chocolate in cravers vs. non-cravers
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford, UK
Eur J Neurosci 26:1067-76. 2007
..Understanding individual differences in brain responses to very pleasant foods helps in the understanding of the mechanisms that drive the liking for specific foods and thus intake of those foods...
- Spatial view cells in the primate hippocampus and memory recall
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, Oxford, UK
Rev Neurosci 17:175-200. 2006
..These findings, and computational models of the hippocampus, help to show how the primate including human hippocampus is involved in episodic memory...
Cognitive influences on the affective representation of touch and the sight of touch in the human brainCiara McCabe
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Soc Cogn Affect Neurosci 3:97-108. 2008
..This is of interest as previous studies have suggested that the CT system is important in affiliative caress-like touch between individuals...
- Different representations of pleasant and unpleasant odours in the human brain
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Eur J Neurosci 18:695-703. 2003
....
- Novel visual stimuli activate a population of neurons in the primate orbitofrontal cortex
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Neurobiol Learn Mem 84:111-23. 2005
..0 spikes/s. These findings indicate that the long-term memory for visual stimuli is information that is represented in a region of the primate anterior orbitofrontal cortex...
- Representation in the human brain of food texture and oral fat
Ivan E de Araujo
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
J Neurosci 24:3086-93. 2004
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- Primate insular/opercular taste cortex: neuronal representations of the viscosity, fat texture, grittiness, temperature, and taste of foods
Justus V Verhagen
Dept. of Experimental Psychology, University of Oxford, S. Parks Road, Oxford OX1 3UD, UK
J Neurophysiol 92:1685-99. 2004
..The results are relevant to understanding the physiological and pathophysiological processes related to how the properties of oral stimuli are represented in the brain and thus to the control of food intake and food selection...
- Self-organizing path integration using a linked continuous attractor and competitive network: path integration of head direction
Simon M Stringer
Centre for Computational Neuroscience, Department of Experimental Psychology, Oxford University, South Parks Road, Oxford, UK
Network 17:419-45. 2006
..Analogous networks in the hippocampal system could self-organize to perform path integration of place and spatial view representations...
- How cognition modulates affective responses to taste and flavor: top-down influences on the orbitofrontal and pregenual cingulate cortices
Fabian Grabenhorst
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Cereb Cortex 18:1549-59. 2008
..This is an important way in which cognition influences the neural mechanisms that control appetite...
- Umami: a delicious flavor formed by convergence of taste and olfactory pathways in the human brain
Ciara McCabe
Department of Experimental Psychology, University of Oxford, Oxford, UK
Eur J Neurosci 25:1855-64. 2007
..Glutamate is thus a flavor enhancer because of the way that it can combine supralinearly with consonant odours in cortical areas where the taste and olfactory pathways converge far beyond the receptors...
- Sensory processing in the brain related to the control of food intake
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Proc Nutr Soc 66:96-112. 2007
..Factors that lead this system to become unbalanced and contribute to overeating and obesity are described...
- Scene perception: inferior temporal cortex neurons encode the positions of different objects in the scene
Nikolaos C Aggelopoulos
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Eur J Neurosci 22:2903-16. 2005
....
- Neural correlates of rapid reversal learning in a simple model of human social interaction
Morten L Kringelbach
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford, OX1 3UD, UK
Neuroimage 20:1371-83. 2003
....
- The use of decoding to analyze the contribution to the information of the correlations between the firing of simultaneously recorded neurons
Leonardo Franco
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Exp Brain Res 155:370-84. 2004
..e. stimulus-dependent synchronization) contribute very little to the encoding of information in the inferior temporal visual cortex about which object or face has been presented...
- Information encoding in the inferior temporal visual cortex: contributions of the firing rates and the correlations between the firing of neurons
Edmund T Rolls
Department of Experimental Psychology, Oxford University, South Parks Road, Oxford OX1 3UD, UK
Biol Cybern 90:19-32. 2004
..Consistent with this, a decoding procedure applied to a population of neurons showed that the information increases approximately linearly with the number of cells in the population...
- Attentional modulation of affective versus sensory processing: functional connectivity and a top-down biased activation theory of selective attention
Fabian Grabenhorst
Department of Experimental Psychology, University of Oxford, Oxford, UK
J Neurophysiol 104:1649-60. 2010
..We then propose a biased activation theory of selective attention to account for the findings and contrast this with a biased competition theory of selective attention...
- Convergence of sensory systems in the orbitofrontal cortex in primates and brain design for emotion
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, Oxford, United Kingdom
Anat Rec A Discov Mol Cell Evol Biol 281:1212-25. 2004
..It is striking that humans and other catarrhines, being visual specialists like other anthropoids, interface the visual system to other sensory systems (e.g., taste and smell) in the orbitofrontal cortex...
- Entorhinal cortex grid cells can map to hippocampal place cells by competitive learning
Edmund T Rolls
Centre for Computational Neuroscience, Department of Experimental Psychology, Oxford University, South Parks Road, Oxford, UK
Network 17:447-65. 2006
..We further show that incorporation of a short term memory trace into the associative learning can help to produce the relatively broad place fields found in the hippocampus...
- Different representations of relative and absolute subjective value in the human brain
Fabian Grabenhorst
Centre for Functional Magnetic Resonance Imaging of the Brain FMRIB, University of Oxford, Oxford, UK
Neuroimage 48:258-68. 2009
..Thus, both relative and absolute subjective value signals which provide important inputs to decision-making processes about which stimulus to choose are separately and simultaneously represented in the human brain...
- Taste, olfactory, and food texture processing in the brain, and the control of food intake
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, England, UK
Physiol Behav 85:45-56. 2005
..Activation of these representations in the orbitofrontal cortex may provide the goal for eating, and understanding them helps to provide a basis for understanding appetite and its disorders...
- Activity of primate subgenual cingulate cortex neurons is related to sleep
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, Oxford OX1 3UD, United Kingdom
J Neurophysiol 90:134-42. 2003
..A decrease in the activation of this area in humans has been observed during the recovery from depression, which we note leads to a more active state of behavior...
- Perirhinal cortex neuronal activity related to long-term familiarity memory in the macaque
Christian Holscher
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Eur J Neurosci 18:2037-46. 2003
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- Neurons in the primate orbitofrontal cortex respond to fat texture independently of viscosity
Justus V Verhagen
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, United Kingdom
J Neurophysiol 90:1514-25. 2003
..These results provide evidence about how oral fat is sensed and are relevant to understanding the physiological and pathophysiological processes related to fat intake...
- Top-down control of visual perception: attention in natural vision
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, UK
Perception 37:333-54. 2008
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- Reward-spatial view representations and learning in the primate hippocampus
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, United Kingdom
J Neurosci 25:6167-74. 2005
..This is an important type of association memory...
- Spatial view cells in the hippocampus, and their idiothetic update based on place and head direction
Edmund T Rolls
Oxford University, Centre for Computational Neuroscience, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Neural Netw 18:1229-41. 2005
..After training, the spatial view cells are updated in the dark by the idiothetically driven head direction and place cells...
- Spatial vs temporal continuity in view invariant visual object recognition learning
Gavin Perry
Oxford University, Centre for Computational Neuroscience, Department of Experimental Psychology, Oxford, UK
Vision Res 46:3994-4006. 2006
..Thus continuous transformation learning is an important principle that may contribute to view invariant object recognition...
- Invariant visual object recognition: a model, with lighting invariance
Edmund T Rolls
Oxford University, Centre for Computational Neuroscience, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, England, United Kingdom
J Physiol Paris 100:43-62. 2006
..The model has also been extended to account for how the visual system can select single objects in complex visual scenes, and how multiple objects can be represented in a scene...
- The functions of the orbitofrontal cortex
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD, England, UK
Brain Cogn 55:11-29. 2004
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- Neurophysiological and computational analyses of the primate presubiculum, subiculum and related areas
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, United Kingdom
Behav Brain Res 174:289-303. 2006
..The role of the subiculum in the backprojection pathways from the hippocampus to the neocortex in a quantitative model of the recall of memories from the hippocampus is described...
- Borderline personality disorder, impulsivity, and the orbitofrontal cortex
Heather A Berlin
Department of Experimental Psychology, University of Oxford
Am J Psychiatry 162:2360-73. 2005
..The authors investigated whether aspects of borderline personality disorder, in particular impulsivity, are associated with orbitofrontal cortex dysfunction...
- An information theoretic approach to the contributions of the firing rates and the correlations between the firing of neurons
Edmund T Rolls
Department of Experimental Psychology, Oxford University, United Kingdom
J Neurophysiol 89:2810-22. 2003
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- Attention in natural scenes: Neurophysiological and computational bases
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, United Kingdom
Neural Netw 19:1383-94. 2006
..Computational models of this processing are described...
- Expected value, reward outcome, and temporal difference error representations in a probabilistic decision task
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, UK
Cereb Cortex 18:652-63. 2008
....
- Consciousness absent and present: a neurophysiological exploration
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, Oxford OX1 3UD, UK
Prog Brain Res 144:95-106. 2004
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- The receptive fields of inferior temporal cortex neurons in natural scenes
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, United Kingdom
J Neurosci 23:339-48. 2003
..The results show that the temporal visual cortex provides an unambiguous representation in natural scenes by responding to the object shown at or close to the fixation point...
- Invariant object recognition in the visual system with novel views of 3D objects
Simon M Stringer
Oxford University, Centre for Computational Neuroscience, Department of Experimental Psychology, Oxford OX1 3UD, England
Neural Comput 14:2585-96. 2002
....
- A computational neuroscience approach to consciousness
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, England, United Kingdom
Neural Netw 20:962-82. 2007
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- Fast, fully automated global and local magnetic field optimization for fMRI of the human brain
James L Wilson
Centre for Functional Magnetic Resonance Imaging of the Brain, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom
Neuroimage 17:967-76. 2002
..The effectiveness of the automated local shim is demonstrated in an olfactory fMRI study where significant activations in the orbitofrontal cortex were very clear when the above method was employed...
- A dynamical systems hypothesis of schizophrenia
Marco Loh
Department of Technology, Universitas Pompeu Fabra, Barcelona, Spain
PLoS Comput Biol 3:e228. 2007
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- "What" and "where" in visual working memory: a computational neurodynamical perspective for integrating FMRI and single-neuron data
Gustavo Deco
Institucion Catalana de Recerca,
J Cogn Neurosci 16:683-701. 2004
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- Neurodynamics of biased competition and cooperation for attention: a model with spiking neurons
Gustavo Deco
Department of Technology, Computational Neuroscience, , Universitat Pompeu Fabra, Barcelona, Spain
J Neurophysiol 94:295-313. 2005
..Further, it is shown that, although NMDA nonlinear effects may be useful in attention, they are not necessary, with nonlinear effects (which may appear multiplicative) being produced in the way just described...
- Sequential memory: a putative neural and synaptic dynamical mechanism
Gustavo Deco
ICREA and Universitat Pompeu Fabra
J Cogn Neurosci 17:294-307. 2005
..The network thus uses adaptation rather than associative synaptic modification to recall the order of the items in a recently presented sequence...
- Decision-making and Weber's law: a neurophysiological model
Gustavo Deco
Institucio Catalana de Recerca i Estudis Avancats (ICREA, Universitat Pompeu Fabra, Department of Technology, Computational Neuroscience, Passeig de Circumvalacio, Barcelona, Spain
Eur J Neurosci 24:901-16. 2006
..Thus the neurophysiological basis for a psychophysical effect, Weber's Law, can be related to statistical fluctuations and divisive inhibition in an attractor decision-making network...
- Attention and working memory: a dynamical model of neuronal activity in the prefrontal cortex
Gustavo Deco
, Universitat Pompeu Fabra, Department of Technology, Computational Neuroscience, Passeig de Circumval.Iaci, 08003 Barcelona, Spain
Eur J Neurosci 18:2374-90. 2003
....
- Object-based visual neglect: a computational hypothesis
Gustavo Deco
Siemens AG, Corporate Technology, Computational Neuroscience, CT IC 4, D-81730 Munich, Germany
Eur J Neurosci 16:1994-2000. 2002
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- An attractor network in the hippocampus: theory and neurophysiology
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, Oxford OX1 3UD, England, United Kingdom
Learn Mem 14:714-31. 2007
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- A simple method for reconditioning epoxy-coated microelectrodes for extracellular single neuron recording
Justus V Verhagen
Department of Experimental Psychology, University of Oxford, South Parks Road, UK
J Neurosci Methods 123:215-7. 2003
..Dipping the electrodes in epoxy followed by curing restores their initial high impedance which is associated with good isolation of single neurons. It is a cost effective and simple procedure...
- How pleasant and unpleasant stimuli combine in different brain regions: odor mixtures
Fabian Grabenhorst
University of Oxford, Department of Experimental Psychology, Oxford OX1 3UD, United Kingdom
J Neurosci 27:13532-40. 2007
....
- Human cortical responses to water in the mouth, and the effects of thirst
Ivan E T de Araujo
Department of Experimental Psychology, University of Oxford, South Parks Road, Oxford OX1 3UD Kingdom
J Neurophysiol 90:1865-76. 2003
..The activity of the rostral anterior cingulate cortex thus appears to reflect the thirst level or motivational state of the subjects...
- Human cortical representation of oral temperature
Steve Guest
Center for Neurosensory Disorders, School of Dentistry, University of North Carolina, Chapel Hill, NC, United States
Physiol Behav 92:975-84. 2007
..Bringing together these different oral representations in the same brain regions may enable particular combinations to influence the pleasantness of foods...
- Neuronal selectivity, population sparseness, and ergodicity in the inferior temporal visual cortex
Leonardo Franco
Depto de Lenguajes y Cs de la Computacion, Universidad de Malaga, Campus de Teatinos s n, 29071 Malaga, Spain
Biol Cybern 96:547-60. 2007
..For this to occur, the different neurons must have uncorrelated tuning profiles to the set of stimuli...
- Methamphetamine activates reward circuitry in drug naïve human subjects
Birgit A Vollm
Department of Psychiatry, University of Oxford, Warneford Hospital, Oxford, UK
Neuropsychopharmacology 29:1715-22. 2004
..Our data also support recent hypotheses suggesting a central role for the orbitofrontal cortex in drug reinforcement and the development of addiction...
- A unified model of spatial and episodic memory
Edmund T Rolls
Department of Experimental Psychology, University of Oxford, South Parks Road, UK
Proc Biol Sci 269:1087-93. 2002
..We thus show that episodic memory and spatial theories of medial temporal lobe function can be combined in a unified model...
- Synaptic and spiking dynamics underlying reward reversal in the orbitofrontal cortex
Gustavo Deco
, Universitat Pompeu Fabra, Dept. of Technology Computational Neuroscience, Passeig de Circumval.laci, 8, 08003 Barcelona, Spain
Cereb Cortex 15:15-30. 2005
....
- Invariant global motion recognition in the dorsal visual system: a unifying theory
Edmund T Rolls
Oxford University, Centre for Computational Neuroscience, Department of Experimental Psychology, Oxford OX1 3UD, England
Neural Comput 19:139-69. 2007
..Thus, the dorsal and ventral visual systems may share some similar computational principles...
- A computational theory of hippocampal function, and empirical tests of the theory
Edmund T Rolls
University of Oxford, Department of Experimental Psychology, South Parks Road, Oxford OX1 3UD, United Kingdom
Prog Neurobiol 79:1-48. 2006
..The perforant path input to DG is implicated in learning, to CA3 in retrieval from CA3, and to CA1 in retrieval after longer time intervals ("intermediate-term memory")...
