T Roehrs

Summary

Publications

  1. ncbi request reprint Risk-taking behavior: effects of ethanol, caffeine, and basal sleepiness
    Timothy Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, MI 48202, USA
    Sleep 27:887-93. 2004
  2. ncbi request reprint Sleepiness and the reinforcing and subjective effects of methylphenidate
    T Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Exp Clin Psychopharmacol 7:145-50. 1999
  3. ncbi request reprint Reinforcing and subjective effects of methylphenidate: dose and time in bed
    Timothy Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Exp Clin Psychopharmacol 12:180-9. 2004
  4. ncbi request reprint Hypnotics: an update
    Timothy Roehrs
    Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Curr Neurol Neurosci Rep 3:181-4. 2003
  5. ncbi request reprint Sex differences in the polysomnographic sleep of young adults: a community-based study
    Timothy Roehrs
    Department of Psychiatry and Behavioral Neurosciences, Sleep Disorders and Research Center, School of Medicine, Wayne State University, Henry Ford Hospital, Detroit, MI 48202, USA
    Sleep Med 7:49-53. 2006
  6. ncbi request reprint 'Hypnotic' prescription patterns in a large managed-care population
    Timothy Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, MI 48202, USA
    Sleep Med 5:463-6. 2004
  7. ncbi request reprint Effects of sleep loss on waking actigraphy
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center and Department of Psychiatry and Behavioral Neuroscience, Wayne State University, School of Medicine, Detroit MI 48202, USA
    Sleep 23:793-7. 2000
  8. ncbi request reprint Sleep loss and REM sleep loss are hyperalgesic
    Timothy Roehrs
    Henry Ford Health System, Sleep Disorders and Research Center, Detroit, MI 48202, USA
    Sleep 29:145-51. 2006
  9. ncbi request reprint Caffeine: sleep and daytime sleepiness
    Timothy Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, 2799 W Grand Blvd, CFP 3, Detroit, MI 48202, USA
    Sleep Med Rev 12:153-62. 2008
  10. ncbi request reprint Nighttime versus daytime hypnotic self-administration
    Timothy Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, 2799 West Grand Boulevard, CFP 3, Detroit, MI 48202, USA
    Psychopharmacology (Berl) 161:137-42. 2002

Research Grants

  1. Abuse Liability Associated with Chronic Hypnotic Use
    Timothy Roehrs; Fiscal Year: 2007
  2. Abuse Liability Associated with Chronic Hypnotic Use
    Timothy Roehrs; Fiscal Year: 2006
  3. Abuse Liability Associated with Chronic Hypnotic Use
    Timothy Roehrs; Fiscal Year: 2005
  4. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2005
  5. Abuse Liability Associated with Chronic Hypnotic Use
    Timothy Roehrs; Fiscal Year: 2004
  6. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2004
  7. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2003
  8. SLEEPINESS AND THE REINFORCING EFFECT OF METHYLPHENIDATE
    Timothy Roehrs; Fiscal Year: 2002
  9. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2002
  10. SLEEPINESS AND THE REINFORCING EFFECT OF METHYLPHENIDATE
    Timothy Roehrs; Fiscal Year: 2001

Detail Information

Publications60

  1. ncbi request reprint Risk-taking behavior: effects of ethanol, caffeine, and basal sleepiness
    Timothy Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, MI 48202, USA
    Sleep 27:887-93. 2004
    ..The aims were to determine whether sleepiness and ethanol degrade psychomotor speed and risky choice and whether caffeine attenuates these effects...
  2. ncbi request reprint Sleepiness and the reinforcing and subjective effects of methylphenidate
    T Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Exp Clin Psychopharmacol 7:145-50. 1999
    ..Drug was chosen on 88% of days after 4 hr, but only 29% of days after 8 hr. Preference for the drug depends on sleepiness and is mediated by performance-enhancing and fatigue-altering effects...
  3. ncbi request reprint Reinforcing and subjective effects of methylphenidate: dose and time in bed
    Timothy Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Exp Clin Psychopharmacol 12:180-9. 2004
    ..These results indicate that sleepiness modulates the reinforcing and subjective effects of methylphenidate...
  4. ncbi request reprint Hypnotics: an update
    Timothy Roehrs
    Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Curr Neurol Neurosci Rep 3:181-4. 2003
    ..The important remaining question is whether, and how, the efficacy and safety of the BZRAs change with chronic use...
  5. ncbi request reprint Sex differences in the polysomnographic sleep of young adults: a community-based study
    Timothy Roehrs
    Department of Psychiatry and Behavioral Neurosciences, Sleep Disorders and Research Center, School of Medicine, Wayne State University, Henry Ford Hospital, Detroit, MI 48202, USA
    Sleep Med 7:49-53. 2006
    ..Given the higher prevalence of sleep-related breathing disturbance in men, this study assessed sex differences in sleep in a large, non-clinical sample of adults and controlled for primary sleep disorders...
  6. ncbi request reprint 'Hypnotic' prescription patterns in a large managed-care population
    Timothy Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, 2799 West Grand Blvd, Detroit, MI 48202, USA
    Sleep Med 5:463-6. 2004
    ..This study assessed the characteristics of the prescriptions for insomnia and of the patients receiving those prescriptions...
  7. ncbi request reprint Effects of sleep loss on waking actigraphy
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center and Department of Psychiatry and Behavioral Neuroscience, Wayne State University, School of Medicine, Detroit MI 48202, USA
    Sleep 23:793-7. 2000
    ..To assess the effect of sleep loss and the effect of a sedating drug on waking actigraphy..
  8. ncbi request reprint Sleep loss and REM sleep loss are hyperalgesic
    Timothy Roehrs
    Henry Ford Health System, Sleep Disorders and Research Center, Detroit, MI 48202, USA
    Sleep 29:145-51. 2006
    ..We report the first data showing, in healthy, pain-free, individuals, that modest reductions of sleep time and specific loss of rapid eye movement (REM) sleep produces hyperalgesia the following morning...
  9. ncbi request reprint Caffeine: sleep and daytime sleepiness
    Timothy Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, 2799 W Grand Blvd, CFP 3, Detroit, MI 48202, USA
    Sleep Med Rev 12:153-62. 2008
    ..The risks to sleep and alertness of regular caffeine use are greatly underestimated by both the general population and physicians...
  10. ncbi request reprint Nighttime versus daytime hypnotic self-administration
    Timothy Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, 2799 West Grand Boulevard, CFP 3, Detroit, MI 48202, USA
    Psychopharmacology (Berl) 161:137-42. 2002
    ..Previous studies have shown that insomniacs self-administer hypnotics at high nightly rates. This study assessed whether insomniacs' self-administration of hypnotics extended to the daytime...
  11. ncbi request reprint Ethanol and sleep loss: a "dose" comparison of impairing effects
    Timothy Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202, USA
    Sleep 26:981-5. 2003
    ..This study compared the "dose"-related sedative, performance-impairing, and amnestic effects of sleep loss to those of ethanol ingestion...
  12. ncbi request reprint Experimental sleep fragmentation
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202
    Sleep 17:438-43. 1994
    ....
  13. ncbi request reprint Polysomnographic, performance, and personality differences of sleepy and alert normals
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202
    Sleep 13:395-402. 1990
    ..The data were interpreted as indicating that the sleepy subjects had a sleep debt due to chronic sleep restriction...
  14. ncbi request reprint The alerting effects of short and long naps in narcoleptic, sleep deprived, and alert individuals
    T Helmus
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Sleep 20:251-7. 1997
    ..In contrast, for narcoleptic patients the beneficial effects of the nap were lost when tested 3 hours later. These results show that narcoleptic patients benefit from a longer nap but that these benefits are short-lived...
  15. ncbi request reprint The frequency of multiple sleep onset REM periods among subjects with no excessive daytime sleepiness
    C Bishop
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Sleep 19:727-30. 1996
    ..Further investigations into the determinants of multiple SOREMPs and their reliability among asymptomatic populations are warranted...
  16. ncbi request reprint Auditory awakening thresholds in sleepy and alert individuals
    L Rosenthal
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan 48202 USA
    Sleep 19:290-5. 1996
    ..This differential rate of decline in AATs is suggested to be related to the differences in sleep homeostasis among alert and sleepy individuals...
  17. ncbi request reprint Effects of sleep deprivation on daytime sleepiness in primary insomnia
    E Stepanski
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Sleep 23:215-9. 2000
    ..This study investigated changes in MSLT scores and recovery sleep following total sleep deprivation in subjects with insomnia as compared to normal sleepers...
  18. ncbi request reprint Phase advance in moderately sleepy and alert normals
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202, USA
    Sleep 19:417-22. 1996
    ....
  19. ncbi request reprint Sedative effects and plasma concentrations following single doses of triazolam, diphenhydramine, ethanol and placebo
    T Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan 48202
    Sleep 16:301-5. 1993
    ..5 hours. Ethanol reached zero, but triazolam and diphenhydramine did not. Continued sedation (sedative effects after plasma concentration reached zero) was observed with ethanol...
  20. ncbi request reprint Daytime alertness in patients with chronic insomnia compared with asymptomatic control subjects
    E Stepanski
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan
    Sleep 11:54-60. 1988
    ..This tendency may be exacerbated by other factors (e.g., personality disorder, periodic leg movements) also associated with insomnia...
  21. ncbi request reprint Treatment regimen and hypnotic self-administration
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, 2799 West Grand Blvd, Detroit, MI 48202, USA
    Psychopharmacology (Berl) 155:11-7. 2001
    ..CONCLUSIONS: The data of this study are consistent with the view that hypnotic self-administration by insomniacs is therapy-seeking behavior and not drug abuse...
  22. ncbi request reprint The detection of brief daytime sleep episodes
    L Rosenthal
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Mich, USA
    Sleep 22:211-4. 1999
    ..In the present study we evaluated the characteristics of sleep-onset detection (during daytime nap opportunities) as a function of differing sleep lengths among healthy, asymptomatic subjects...
  23. ncbi request reprint Neuropsychological function in obstructive sleep apnea syndrome (OSAS) compared to chronic obstructive pulmonary disease (COPD)
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202, USA
    Sleep 18:382-8. 1995
    ..These deficits in psychomotor and attention appear to be specifically related to patients group (OSAS vs. COPD), but the other deficits found in complex reasoning and memory are nonspecific...
  24. ncbi request reprint Daytime sleepiness in young adults
    B Levine
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan
    Sleep 11:39-46. 1988
    ..The relation between nocturnal sleep efficiency and daytime sleepiness suggests that the increased sleepiness of average young adults is due to mild sleep restriction...
  25. ncbi request reprint Sleep extension in sleepy and alert normals
    T Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI 48202
    Sleep 12:449-57. 1989
    ..However, sleepy subjects never achieved the baseline level of sleepiness/alertness seen in the alert subjects...
  26. ncbi request reprint A two-week sleep extension in sleepy normals
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202, USA
    Sleep 19:576-82. 1996
    ..Their short average daily sleep latency was a result of causes other than chronic insufficient sleep...
  27. ncbi request reprint Fragmenting sleep diminishes its recuperative value
    B Levine
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, MI 48202
    Sleep 10:590-9. 1987
    ..Although the natural sleep provided recuperation relative to no sleep or fragmented sleep, it did not restore daytime sleepiness to the screening level...
  28. ncbi request reprint Zolpidem in the treatment of transient insomnia: a double-blind, randomized comparison with placebo
    T Roth
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan 48202, USA
    Sleep 18:246-51. 1995
    ..5-mg and 10-mg zolpidem dose groups and placebo. This study demonstrates that zolpidem at 7.5 mg and 10 mg is effective in the treatment of transient insomnia...
  29. ncbi request reprint Sleep physiology and pathophysiology
    T Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan, USA
    Clin Cornerstone 2:1-15. 2000
    ..This review will describe normal sleep physiology and its regulation as well as the major disorders of sleep and their underlying pathophysiology...
  30. ncbi request reprint Epidemiology of alcohol and medication as aids to sleep in early adulthood
    E O Johnson
    Department of Psychiatry, Henry Ford Health Sciences Center, Detroit, Mich 48202 3450, USA
    Sleep 21:178-86. 1998
    ..2) among those who use these substances for sleep problems, what are the patterns of use? and (3) are there social factors, independent of sleep characteristics, that increase the likelihood of alcohol and medication use to aid sleep?..
  31. ncbi request reprint Hypnotic residual effects of benzodiazepines with repeated administration
    T Roehrs
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Michigan 48202
    Sleep 9:309-16. 1986
    ..During the late phase, flurazepam did not disrupt performance but still affected the MSLT. Temazepam affected neither index the next day during the late phase...
  32. ncbi request reprint Vulnerability to stress-related sleep disturbance and hyperarousal
    Christopher Drake
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Sleep 27:285-91. 2004
    ..To determine the presence of a hypothesized trait vulnerability to sleep disturbance and hyperarousal...
  33. ncbi request reprint Ethanol and caffeine effects on daytime sleepiness/alertness
    M Lumley
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan 48202
    Sleep 10:306-12. 1987
    ..In this condition latencies were similar to those of the caffeine and 5- or 8-h TIBs...
  34. ncbi request reprint Test-retest reliability of the MSLT
    A Zwyghuizen-Doorenbos
    Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan 48202
    Sleep 11:562-5. 1988
    ..However, as the number of tests comprising the MSLT was reduced below three, the reliability was reduced such that only 50% or less of the variance could be predicted...
  35. ncbi request reprint The effects of REM sleep deprivation on the level of sleepiness/alertness
    K Nykamp
    Henry Ford Hospital, Sleep Disorders and Research Center, Detroit, Mich. 48202, USA
    Sleep 21:609-14. 1998
    ..The mechanism by which REM deprivation exerts its alerting effects is unknown and will require future research...
  36. ncbi request reprint Sleep, sleepiness, and alcohol use
    T Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Department of Psychiatry and Behavioral Neuroscience, Wayne State University, Detroit, Michigan, USA
    Alcohol Res Health 25:101-9. 2001
    ..Alcohol's effects on other physiological functions during sleep have yet to be documented thoroughly and unequivocally...
  37. ncbi request reprint The treatment of chronic insomnia: drug indications, chronic use and abuse liability. Summary of a 2001 New Clinical Drug Evaluation Unit meeting symposium
    Wallace B Mendelson
    Sleep Med Rev 8:7-17. 2004
    ..All currently available agents, while effective and safe, do not achieve this ideal. The next few years are likely to see the appearance of a variety of agents with new and promising mechanisms of action...
  38. ncbi request reprint Insomnia: epidemiology, characteristics, and consequences
    Thomas Roth
    Division of Sleep Medicine, Sleep Disorders and Research Center, Henry Ford Hospital, Detroit, Michigan, USA
    Clin Cornerstone 5:5-15. 2003
    ..The most consistent impact of insomnia is a high risk of depression...
  39. ncbi request reprint Caffeine reversal of ethanol effects on the multiple sleep latency test, memory, and psychomotor performance
    Christopher L Drake
    Sleep Disorder and Reserch Center, Henry Ford Hospital, Detroit, MI 48202, USA
    Neuropsychopharmacology 28:371-8. 2003
    ..Thus, caffeine, similar to other stimulants, can reverse the physiologically sedating effects of ethanol, although other negative effects remain...
  40. pmc Stress-related sleep disturbance and polysomnographic response to caffeine
    Christopher L Drake
    Henry Ford Hospital Sleep Disorders and Research Center, and Department of Psychiatry and Behavioral Neurosciences, Wayne State College of Medicine, Detroit, MI 48202, USA
    Sleep Med 7:567-72. 2006
    ..To determine the sleep response to caffeine in individuals vulnerable to stress-related sleep disturbance as measured by polysomnography...
  41. ncbi request reprint Substance use for insomnia in Metropolitan Detroit
    Timothy Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, and Department of Psychiatry and Behavioral Neuroscience, School of Medicine, Wayne State University, Detroit, MI, USA
    J Psychosom Res 53:571-6. 2002
    ..Studies have reported approximately 30% of insomniacs self-medicate with alcohol or over-the-counter (OTC) medications. This study was done to identify determinants and risks of different insomnia therapeutics...
  42. ncbi request reprint The status of sleep abnormalities as a diagnostic test for major depressive disorder
    C L Arfken
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University, Detroit, MI 48207, USA Electronic address
    J Affect Disord 156:36-45. 2014
    ..Psychiatry lags other fields in development of diagnostic tests...
  43. ncbi request reprint Alexithymia and polysomnographic measures of sleep in healthy adults
    R Bazydlo
    Department of Psychology, Wayne State University, Detroit, Michigan 48202, USA
    Psychosom Med 63:56-61. 2001
    ....
  44. ncbi request reprint Shift work sleep disorder: prevalence and consequences beyond that of symptomatic day workers
    Christopher L Drake
    Henry Ford Hospital Sleep Disorders and Research Center, Detroit, MI 48202, USA
    Sleep 27:1453-62. 2004
    ..The present study was designed to determine the relative prevalence and negative consequences associated with shift work sleep disorder in a representative sample drawn from the working population of metropolitan Detroit...
  45. ncbi request reprint Insomnia causes, consequences, and therapeutics: an overview
    Christopher L Drake
    Henry Ford Hospital Sleep Disorders and Research Center, CFP3, Detroit, Michigan 48202, USA
    Depress Anxiety 18:163-76. 2003
    ..The inadequate treatment of insomnia leads to several important and under-recognized consequences including subsequent development of psychiatric disease and increased substance use...
  46. pmc Effects of acute 3,4-methylenedioxymethamphetamine on sleep and daytime sleepiness in MDMA users: a preliminary study
    Surilla Randall
    Sleep Disorders and Research Center Henry Ford Health System, Detroit, Michigan 48202, USA
    Sleep 32:1513-9. 2009
    ..This study was designed to establish the effects of acute MDMA or placebo administration and sleep restriction on sleep and daytime sleepiness...
  47. ncbi request reprint Insomnia: pathophysiology and implications for treatment
    Thomas Roth
    Sleep Disorders and Research Center, Henry Ford Hospital, 2799 West Grand Boulevard, Detroit, MI 48202, USA
    Sleep Med Rev 11:71-9. 2007
    ..These insights have implications for managing chronic primary insomnia, such as use of antiglucocorticoid agents...
  48. pmc The 10-year risk of verified motor vehicle crashes in relation to physiologic sleepiness
    Christopher Drake
    Sleep Disorders and Research Center, Henry Ford Hospital, 2799 West Grand Blvd, CFP3, Detroit, MI 48202, USA
    Sleep 33:745-52. 2010
    ..The purpose of this study was to determine the risk of DMV documented crashes as a function of physiological sleepiness in a population-based sample...
  49. ncbi request reprint The association between obesity and short sleep duration: a population-based study
    Meeta Singh
    Henry Ford Hospital Sleep Disorders and Research Center, Wayne State College of Medicine, Detroit, MI 49202, USA
    J Clin Sleep Med 1:357-63. 2005
    ..To assess the association between nightly total sleep time (TST) and obesity in an epidemiologic sample of metropolitan Detroit, Michigan...
  50. ncbi request reprint Sleep hygiene practices in a population-based sample of insomniacs
    Catherine D Jefferson
    Henry Ford Hospital Sleep Disorders and Research Center, Detroit, MI, USA
    Sleep 28:611-5. 2005
    ..The present study was designed to assess selected aspects of sleep hygiene from a population-based sample of individuals with insomnia compared to age- and sex-matched controls...
  51. ncbi request reprint Sleep disorders: an overview
    Timothy Roehrs
    Sleep Disorders and Research Center, Henry Ford Hospital, Department of Psychiatry and Behavioral Neurosciences Wayne State University School of Medicine, Detroit, Michigan 48202, USA
    Clin Cornerstone 6:S6-16. 2004
    ....
  52. ncbi request reprint Sleep and pain: interaction of two vital functions
    Timothy Roehrs
    Henry Ford Health System, Sleep Disorders and Research Center, Detroit, MI 48202, USA
    Semin Neurol 25:106-16. 2005
    ..Few of the treatment studies have done such, and as a result no clear consensus on treatment approaches, much less on differential etiology-based treatment strategies, has emerged...
  53. ncbi request reprint An evaluation of the efficacy and safety of eszopiclone over 12 months in patients with chronic primary insomnia
    Thomas Roth
    Henry Ford Hospital Sleep Center, 2799 West Grand Blvd, CFP 3, Detroit, MI 48202, USA
    Sleep Med 6:487-95. 2005
    ..A double-blind placebo-controlled study of eszopiclone found significant, sustained improvement in sleep and daytime function. The 6-month open-label extension phase is described herein...
  54. ncbi request reprint Effects of REM sleep and ambient temperature on hot flash-induced sleep disturbance
    Robert R Freedman
    Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48201, USA
    Menopause 13:576-83. 2006
    ..To determine whether hot flashes produce sleep disturbance in postmenopausal women...
  55. ncbi request reprint Tolerance to daytime sedative effects of H1 antihistamines
    Gary S Richardson
    Sleep Disorders Clinic and Research Center, Henry Ford Hospital, Detroit, Michigan 48202, USA
    J Clin Psychopharmacol 22:511-5. 2002
    ..While other antihistamines and dosing regimens may differ, these results suggest that tolerance to the sedation produced by these drugs develops with remarkable rapidity...
  56. ncbi request reprint Mu-opioid self-administration vs passive administration in heroin abusers produces differential EEG activation
    Mark K Greenwald
    Substance Abuse Research Division, Department of Psychiatry and Behavioral Neurosciences, Wayne State University School of Medicine, Detroit, MI 48207, USA
    Neuropsychopharmacology 30:212-21. 2005
    ..The EEG increase and its attenuation by naloxone agree with preclinical evidence and suggest that SA-related EEG responses were mediated by opioid receptors...
  57. ncbi request reprint Lack of sleep disturbance from menopausal hot flashes
    Robert R Freedman
    Department of Psychiatry, Wayne State University School of Medicine, Detroit, Michigan 48201, USA
    Fertil Steril 82:138-44. 2004
    ..To determine whether hot flashes produce disordered sleep in symptomatic postmenopausal women...
  58. ncbi request reprint Chronic insufficient sleep and its recovery
    Timothy A Roehrs
    Sleep Med 4:5-6. 2003
  59. ncbi request reprint Sleep disturbance in menopause
    Robert R Freedman
    Department of Psychiatry, Wayne State University School of Medicine, and Henry Ford Hospital Sleep Disorders Center, Detroit, MI 48201, USA
    Menopause 14:826-9. 2007
    ..To determine the sources of sleep complaints in peri- and postmenopausal women reporting disturbed sleep...
  60. pmc The Acute Hangover Scale: A new measure of immediate hangover symptoms
    Damaris J Rohsenow
    Center for Alcohol and Addiction Studies, Box G BH Brown University, Providence, RI 02912, USA
    Addict Behav 32:1314-20. 2007
    ..The present investigation combined data across three studies of residual alcohol effects to establish the properties of a new Acute Hangover Scale (AHS) based on symptoms supported in previous lab studies...

Research Grants15

  1. Abuse Liability Associated with Chronic Hypnotic Use
    Timothy Roehrs; Fiscal Year: 2007
    ....
  2. Abuse Liability Associated with Chronic Hypnotic Use
    Timothy Roehrs; Fiscal Year: 2006
    ....
  3. Abuse Liability Associated with Chronic Hypnotic Use
    Timothy Roehrs; Fiscal Year: 2005
    ....
  4. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2005
    ..abstract_text> ..
  5. Abuse Liability Associated with Chronic Hypnotic Use
    Timothy Roehrs; Fiscal Year: 2004
    ....
  6. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2004
    ..abstract_text> ..
  7. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2003
    ..abstract_text> ..
  8. SLEEPINESS AND THE REINFORCING EFFECT OF METHYLPHENIDATE
    Timothy Roehrs; Fiscal Year: 2002
    ..And finally during year five the interaction of behavioral demand placed on subjects and different levels of sleepiness-alertness will be the focus. ..
  9. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2002
    ..abstract_text> ..
  10. SLEEPINESS AND THE REINFORCING EFFECT OF METHYLPHENIDATE
    Timothy Roehrs; Fiscal Year: 2001
    ..And finally during year five the interaction of behavioral demand placed on subjects and different levels of sleepiness-alertness will be the focus. ..
  11. Insomnia as a Path to Alcohol Abuse
    Timothy Roehrs; Fiscal Year: 2001
    ..abstract_text> ..
  12. SLEEPINESS AND THE REINFORCING EFFECT OF METHYLPHENIDATE
    Timothy Roehrs; Fiscal Year: 2000
    ..And finally during year five the interaction of behavioral demand placed on subjects and different levels of sleepiness-alertness will be the focus. ..
  13. SLEEPINESS AND THE REINFORCING EFFECT OF METHYLPHENIDATE
    Timothy Roehrs; Fiscal Year: 1999
    ..And finally during year five the interaction of behavioral demand placed on subjects and different levels of sleepiness-alertness will be the focus. ..