Frequency difference gating: a multivariate method for identifying subsets that differ between samplesM Roederer
Vaccine Research Center, NIH, Bethesda, Maryland 20892 3015, USA
Cytometry 45:56-64. 2001
..Such a method could be used to identify responses (i.e., by comparing cell samples before and after stimulation) in exquisite detail by allowing complete analysis of the collected data on only those events which have responded...
- Spectral compensation for flow cytometry: visualization artifacts, limitations, and caveats
M Roederer
Vaccine Research Center, NIH, Bethesda, Maryland 20892 3015, USA
Cytometry 45:194-205. 2001
....
- Probability binning comparison: a metric for quantitating univariate distribution differences
M Roederer
Vaccine Research Center, NIH, Bethesda, Maryland 20892 3015, USA
Cytometry 45:37-46. 2001
..g., a control and test sample) are statistically significantly different is useful to detect a response, or to provide feedback regarding instrument stability by detecting when collected data varies significantly over time...
- Eleven-color flow cytometry. A powerful tool for elucidation of the complex immune system
S C De Rosa
Vaccine Research Center, National Institute for Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA
Clin Lab Med 21:697-712, vii. 2001
..Although the implementation of this technology in the clinic is still several years off, it can serve to identify important correlates of immune function that can be measured with today's technology...
- Probability binning comparison: a metric for quantitating multivariate distribution differences
M Roederer
Vaccine Research Center, NIH, Bethesda, Maryland 20892 3015, USA
Cytometry 45:47-55. 2001
..Multivariate comparisons could also be useful for providing feedback about instrument stability, when only subtle changes in measurements are occurring...
CD4 T cell subsets in the mucosa are CD28+Ki-67-HLA-DR-CD69+ but show differential infection based on alpha4beta7 receptor expression during acute SIV infectionM Kader
Uniformed Services University of Health Sciences, Bethesda, MD 20814, USA
J Med Primatol 38:24-31. 2009
..The demonstration the HIV/SIVcan use the alpha4beta7 receptor for viral entry suggests that these viruses selectively target CD4 T cells in the mucosa that express high levels of alpha4beta7 receptor...
- Vdelta1 and Vdelta2 gammadelta T cells express distinct surface markers and might be developmentally distinct lineages
S C De Rosa
Vaccine Research Center, National Institutes of Health, Bethesda, Maryland 20814, USA
J Leukoc Biol 70:518-26. 2001
..The disruption of the supply of normal, thymus-derived T cells in HIV-infected individuals might be responsible for the shift in the Vdelta2/Vdelta1 ratio that occurs in the blood of individuals with HIV disease...
Comparison of systemic and mucosal vaccination: impact on intravenous and rectal SIV challengeD L Bolton
Immunotechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, Maryland, USA
Mucosal Immunol 5:41-52. 2012
..The similar outcomes achieved by systemic and airway mucosal immunization support AE delivery as a safe, effective, and less invasive alternative to parenteral vaccination...
- Alpha4(+)beta7(hi)CD4(+) memory T cells harbor most Th-17 cells and are preferentially infected during acute SIV infection
M Kader
Deptartment of Microbiology and Immunology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
Mucosal Immunol 2:439-49. 2009
....
