Non-invasive assessment of vulnerable plaqueGaston A Rodriguez Granillo
Otamendi Hospital, Clinica La Sagrada Familia, Consejo Nacional de Investigaciones Cientificas y Tecnicas CONICET, Department of Cardiovascular Imaging, Azcuenaga 870, Buenos Aires, Argentina 54 11 49648740 54 11 49648740
Expert Opin Med Diagn 3:53-66. 2009
..The value of the technique itself might result, potentially, in a better estimation of the relative risk of an invidual plaque to rupture...
- Left ventricular filling patterns in patients with previous myocardial infarction measured by conventional cine cardiac magnetic resonance
Gaston A Rodriguez-Granillo
Department of Cardiovascular Imaging, Clínica La Sagrada Familia ENERI, Buenos Aires, Argentina
Int J Cardiovasc Imaging 28:795-801. 2012
..04). At multivariate analysis, MI size was the only independent predictor of the lowest PFR (p = 0.017). Infarct size has an impact on LV filling profiles, as assessed by conventional cine CMR without additional specific pulse sequences...
Prevalence and characteristics of major and minor coronary artery anomalies in an adult population assessed by computed tomography coronary angiographyGaston A Rodriguez-Granillo
Department of Cardiovascular Imaging, Otamendi Hospital, Azcuenaga 870 C1115AAB, Buenos Aires, Argentina
EuroIntervention 4:641-7. 2009
..We sought to explore the prevalence and characteristics of major and minor CAAs using computed tomography coronary angiography (CCTA)...
- Early assessment of myocardial viability by the use of delayed enhancement computed tomography after primary percutaneous coronary intervention
Gaston A Rodriguez-Granillo
Department of Cardiovascular Imaging, Otamendi Hospital, C1115AAB, Buenos Aires, Argentina
JACC Cardiovasc Imaging 2:1072-81. 2009
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- Signal density of left ventricular myocardial segments and impact of beam hardening artifact: implications for myocardial perfusion assessment by multidetector CT coronary angiography
Gaston A Rodriguez-Granillo
Department of Cardiovascular Imaging, Otamendi Hospital, Azcuenaga 870 C1115AAB, Buenos Aires, Argentina
Int J Cardiovasc Imaging 26:345-54. 2010
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- Meta-analysis of the studies assessing temporal changes in coronary plaque volume using intravascular ultrasound
Gaston A Rodriguez-Granillo
Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
Am J Cardiol 99:5-10. 2007
..13 mm(3), 95% confidence interval -4.42 to 4.68, p = 0.96). In conclusion, statin therapy, particularly when achieving the target LDL level, appears to promote a significant regression of coronary plaque volume as measured by IVUS...
- Multislice CT coronary angiography for the detection of burden, morphology and distribution of atherosclerotic plaques in the left main bifurcation
Gaston A Rodriguez-Granillo
Department of Cardiovascular Imaging, Otamendi Hospital, Buenos Aires, Argentina
Int J Cardiovasc Imaging 23:389-92. 2007
..The angle of the left main bifurcation and the presence of plaques within the bifurcation are closely related...
- Modified scan protocol using multislice CT coronary angiography allows high quality acquisitions in obese patients: a case report
Gaston A Rodriguez-Granillo
Departamento de Imágenes en Cardiología, Sanatorio Otamendi, Azcuenaga 870, C1115AAB Buenos Aires, Argentina
Int J Cardiovasc Imaging 23:265-7. 2007
..Providing this complex population an accurate, non-invasive imaging technique represents a major step-forward in cardiovascular imaging...
- Effect of perindopril on coronary remodelling: insights from a multicentre, randomized study
Gaston A Rodriguez-Granillo
Department of Interventional Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
Eur Heart J 28:2326-31. 2007
..This study sought to evaluate the effect of perindopril in coronary remodelling...
- Chronic myocardial infarction detection and characterization during coronary artery calcium scoring acquisitions
Gaston A Rodriguez-Granillo
Department of Cardiovascular Imaging, Otamendi Hospital, Azcuenaga 870 C1115AAB, Buenos Aires, Argentina
J Cardiovasc Comput Tomogr 4:99-107. 2010
..In addition to a limited capillary density, chronic myocardial infarction (MI) commonly contains a considerable amount of adipose tissue...
- Effect of doxycycline on atherosclerosis: from bench to bedside
Gaston A Rodriguez-Granillo
Instituto de Investigaciones Cardiologicas, UBA CONICET, Buenos Aires, Argentina
Recent Pat Cardiovasc Drug Discov 6:42-54. 2011
..We discuss the available evidence and recent patents supporting the role of doxycycline in atherosclerosis...
- Guidance of percutaneous coronary interventions by multidetector row computed tomography coronary angiography
Gaston A Rodriguez-Granillo
Department of Cardiovascular Imaging, Otamendi Hospital, Buenos Aires, Argentina
EuroIntervention 6:773-8. 2011
..In the present article, we discuss the potential application of CTCA for the guidance of PCI, particularly of complex lesions such as chronic total occlusions (CTO) and bifurcations...
- Single-vessel versus bifurcation stenting for the treatment of distal left main coronary artery disease in the drug-eluting stenting era. Clinical and angiographic insights into the Rapamycin-Eluting Stent Evaluated at Rotterdam Cardiology Hospital (RESEA
Marco Valgimigli
Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
Am Heart J 152:896-902. 2006
..CONCLUSIONS: In consecutive patients undergoing catheter-based distal LM intervention, SVS or BS may perform equally under both clinical and angiographic perspective in current DES era...
- "Full metal jacket" (stented length > or =64 mm) using drug-eluting stents for de novo coronary artery lesions
Jiro Aoki
Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
Am Heart J 150:994-9. 2005
..CONCLUSIONS: The use of DES for the treatment of diffuse lesions was associated with a low rate of repeat revascularization, irrespective of stent type. No safety concerns were raised at medium-term follow-up...
- Sirolimus-eluting versus paclitaxel-eluting stent implantation for the percutaneous treatment of left main coronary artery disease: a combined RESEARCH and T-SEARCH long-term analysis
Marco Valgimigli
Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
J Am Coll Cardiol 47:507-14. 2006
..36) and 0.52 +/- 0.42 (p = 0.41) in the PES group, respectively. CONCLUSIONS: In consecutive patients undergoing percutaneous LM intervention, PES may perform closely to SES both in terms of angiographic and long-term clinical outcome...
- Comparison of short- (one month) and long- (twelve months) term outcomes of sirolimus- versus paclitaxel-eluting stents in 293 consecutive patients with diabetes mellitus (from the RESEARCH and T-SEARCH registries)
Andrew T L Ong
Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
Am J Cardiol 96:358-62. 2005
..Patients who required insulin had a significantly higher, crude major adverse cardiac event rate at 1 year compared with those who used oral agents, but this rate became nonsignificant when adjusted for independent predictors of outcome...
- Long-term outcomes after stenting of bifurcation lesions with the "crush" technique: predictors of an adverse outcome
Angela Hoye
Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
J Am Coll Cardiol 47:1949-58. 2006
..Furthermore, the incidence of possible stent thrombosis is of concern and requires further investigation. Kissing balloon post-dilatation is mandatory to reduce side branch restenosis...
- Plaque composition in the left main stem mimics the distal but not the proximal tract of the left coronary artery: influence of clinical presentation, length of the left main trunk, lipid profile, and systemic levels of C-reactive protein
Marco Valgimigli
Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
J Am Coll Cardiol 49:23-31. 2007
..We sought to investigate whether plaques located in the left main stem (LMS) differ in terms of necrotic core content from those sited in the proximal tract of the left coronary artery...
- Percutaneous therapy of bifurcation lesions with drug-eluting stent implantation: the Culotte technique revisited
Angela Hoye
Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
Int J Cardiovasc Intervent 7:36-40. 2005
..Further re-evaluation of this technique utilizing drug-eluting stents, is warranted in the setting of larger randomized studies...
- Long-term effect of perindopril on coronary atherosclerosis progression (from the perindopril's prospective effect on coronary atherosclerosis by angiography and intravascular ultrasound evaluation [PERSPECTIVE] study)
Gaston A Rodriguez Granillo
Department of Cardiology, Thoraxcenter, Erasmus MC, Rotterdam, The Netherlands
Am J Cardiol 100:159-63. 2007
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- Thirty-day incidence and six-month clinical outcome of thrombotic stent occlusion after bare-metal, sirolimus, or paclitaxel stent implantation
Andrew T L Ong
Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
J Am Coll Cardiol 45:947-53. 2005
..Stent thrombosis was associated with a high morbidity and mortality. Bifurcation stenting, when performed in patients with acute myocardial infarction, was associated with an increased risk of ST...
- Coronary calcium significantly affects quantitative analysis of coronary ultrasound: importance for atherosclerosis progression/regression studies
Nico Bruining
Thoraxcenter, Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
Coron Artery Dis 20:409-14. 2009
..Coronary atherosclerosis is a dynamic process, which progresses differently in coronary segments containing noncalcified or calcified plaques. This may have implications for the study of the effects of therapy on progression/regression...
- Efficacy and safety of a double-coated paclitaxel-eluting coronary stent: the EUCATAX trial
Alfredo E Rodriguez
Sanatorio Otamendi, Cardiac Unit, Capital Federal, Buenos Aires, Argentina
Catheter Cardiovasc Interv 77:335-42. 2011
..The aim of this study was the comparison of a new double-coated paclitaxel-eluting coronary stent with bare-metal stent (BMS) in patients undergoing percutaneous coronary intervention...
- Comparison of three-year outcomes after coronary stenting versus coronary artery bypass grafting in patients with multivessel coronary disease, including involvement of the left anterior descending coronary artery proximally (a subanalysis of the arterial
Jiro Aoki
Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
Am J Cardiol 94:627-31. 2004
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- Emerging drugs for coronary restenosis: the role of systemic oral agents the in stent era
Alfredo E Rodriguez
Otamendi Hospital, Post Graduate School of Medicine, Cardiac Unit, Buenos Aires, Argentina
Expert Opin Emerg Drugs 14:561-76. 2009
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- One-year clinical outcome after coronary stenting of very small vessels using 2.25 mm sirolimus- and paclitaxel-eluting stents: a comparison between the RESEARCH and T-SEARCH registries
Gaston A Rodriguez-Granillo
Cardiac Catheterization Laboratory, Thoraxcenter, Erasmus Medical Center, Rotterdam, Kamer Z 120, Dr Molewaterplein 40, Rotterdam, The Netherlands 3015 GD
J Invasive Cardiol 17:409-12. 2005
..The efficacy of sirolimus-eluting stents (SES) compared to paclitaxel-eluting stents (PES) remains unknown. We evaluated the clinical outcomes after implantation of 2.25 mm diameter SES and PES...
- Percutaneous coronary intervention with oral sirolimus and bare metal stents has comparable safety and efficacy to treatment with drug eluting stents, but with significant cost saving: long-term follow-up results from the randomised, controlled ORAR I
Alfredo E Rodriguez
Cardiovascular Research Center CECI, Sanatorio Otamendi, Buenos Aires, Argentina
EuroIntervention 5:255-64. 2009
..How this regimen compares to drug eluting stents (DES) is unknown...
- New coating stent design for patients with high-risk coronary lesions for thrombotic events: early and long-term results of the Camouflage registry
Gilberto Perez
Cardiovascular Research Center CECI, Callao 1441 4B 1024, Capital Federal, Buenos Aires, Argentina
J Invasive Cardiol 21:378-82. 2009
..We sought to determine in a clinical registry the acute and long-term clinical and angiographic outcomes of this BMS design in patients with acute coronary syndromes (ACS) or who were unable to be on long-term clopidogrel therapy...
- Five-year follow-up of the Argentine randomized trial of coronary angioplasty with stenting versus coronary bypass surgery in patients with multiple vessel disease (ERACI II)
Alfredo E Rodriguez
Otamendi Hospital, Buenos Aires, Argentina
J Am Coll Cardiol 46:582-8. 2005
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- Late stent thrombosis mimicking focal restenosis after sirolimus stent implantation: angiographic and intravascular ultrasound appraisal
Carlos Fernandez-Pereira
Interventional Cardiology Department, Otamendi Hospital, Buenos Aires, Argentina
J Invasive Cardiol 18:E294-7. 2006
- Oral rapamycin after coronary bare-metal stent implantation to prevent restenosis: the Prospective, Randomized Oral Rapamycin in Argentina (ORAR II) Study
Alfredo E Rodriguez
Otamendi Hospital, Buenos Aires, Argentina
J Am Coll Cardiol 47:1522-9. 2006
..The purpose of this study was to assess the role of oral rapamycin in decreased restenosis after bare metal stent implantation...
- Late loss of early benefit from drug-eluting stents when compared with bare-metal stents and coronary artery bypass surgery: 3 years follow-up of the ERACI III registry
Alfredo E Rodriguez
Cardiovascular Research Center CECI Sanatorio Otamendi, Callao 1441, 4B 1024, Buenos Aires, Argentina
Eur Heart J 28:2118-25. 2007
..Furthermore, despite continued lower incidence of MACCE, initial advantage over BMS appeared to decrease with time. LST occurred more frequent in DES-treated patients...
