E Rene Rodriguez

Summary

Publications

  1. ncbi request reprint Transplant vasculopathy is associated with increased AlloMap gene expression score
    Mohamad H Yamani
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Kaufman Center for Heart Failure, Cleveland, Ohio 44195, USA
    J Heart Lung Transplant 26:403-6. 2007
  2. ncbi request reprint Update on cardiac transplantation pathology
    Carmela D Tan
    Department of Anatomic Pathology, The Cleveland Clinic, Cleveland, OH 44195, USA
    Arch Pathol Lab Med 131:1169-91. 2007
  3. ncbi request reprint The pathology of heart transplant biopsy specimens: revisiting the 1990 ISHLT working formulation
    E Rene Rodriguez
    Cardiovascular Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Heart Lung Transplant 22:3-15. 2003
  4. pmc Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load
    Eiki Takimoto
    Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    J Clin Invest 115:1221-31. 2005
  5. ncbi request reprint Noninvasive detection of myocardial fibrosis in arrhythmogenic right ventricular cardiomyopathy using delayed-enhancement magnetic resonance imaging
    Harikrishna Tandri
    Division of Cardiology, The Johns Hopkins University, Baltimore, MD 21287, USA
    J Am Coll Cardiol 45:98-103. 2005
  6. ncbi request reprint Evaluation and course of an unusual case of arrhythmogenic right ventricular dysplasia
    Jan Fritz
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Int J Cardiovasc Imaging 22:269-73. 2006
  7. ncbi request reprint Reversible cardiomyopathy caused by administration of interferon alpha
    Aarif Y Khakoo
    Division of Cardiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Nat Clin Pract Cardiovasc Med 2:53-7. 2005
  8. pmc Immunological challenges of cardiac transplantation: the need for better animal models to answer current clinical questions
    Jennifer R Wehner
    Department of Pathology, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    J Clin Immunol 29:722-9. 2009
  9. ncbi request reprint Antithymocyte globulin is associated with complement deposition in cardiac transplant biopsies
    William M Baldwin
    Department of Pathology, The Johns Hopkins University, Baltimore, MD 21205 2196, USA
    Hum Immunol 65:1273-80. 2004
  10. ncbi request reprint Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
    Eiki Takimoto
    Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Ross 835, 720 Rutland Avenue, Baltimore, Maryland 21205, USA
    Nat Med 11:214-22. 2005

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Transplant vasculopathy is associated with increased AlloMap gene expression score
    Mohamad H Yamani
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Kaufman Center for Heart Failure, Cleveland, Ohio 44195, USA
    J Heart Lung Transplant 26:403-6. 2007
    ..2 +/- 3.9 vs 26.1 +/- 6.5, p < 0.001). There was a correlation of AlloMap score with time after transplantation (r = 0.31, p = 0.01). We found transplant vasculopathy to be associated with increased AlloMap score...
  2. ncbi request reprint Update on cardiac transplantation pathology
    Carmela D Tan
    Department of Anatomic Pathology, The Cleveland Clinic, Cleveland, OH 44195, USA
    Arch Pathol Lab Med 131:1169-91. 2007
    ..The grading system for evaluation of heart transplant biopsies published in 1990 was revised in 2004 after more than a decade of implementation...
  3. ncbi request reprint The pathology of heart transplant biopsy specimens: revisiting the 1990 ISHLT working formulation
    E Rene Rodriguez
    Cardiovascular Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Heart Lung Transplant 22:3-15. 2003
  4. pmc Oxidant stress from nitric oxide synthase-3 uncoupling stimulates cardiac pathologic remodeling from chronic pressure load
    Eiki Takimoto
    Division of Cardiology, Department of Medicine, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21205, USA
    J Clin Invest 115:1221-31. 2005
    ..Reversal of this process by BH4 suggests a potential treatment to ameliorate the pathophysiology of chronic pressure-induced hypertrophy...
  5. ncbi request reprint Noninvasive detection of myocardial fibrosis in arrhythmogenic right ventricular cardiomyopathy using delayed-enhancement magnetic resonance imaging
    Harikrishna Tandri
    Division of Cardiology, The Johns Hopkins University, Baltimore, MD 21287, USA
    J Am Coll Cardiol 45:98-103. 2005
    ..We evaluated the role of myocardial delayed-enhancement (MDE) magnetic resonance imaging (MRI) for noninvasive detection of fibrosis in Arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C)...
  6. ncbi request reprint Evaluation and course of an unusual case of arrhythmogenic right ventricular dysplasia
    Jan Fritz
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Int J Cardiovasc Imaging 22:269-73. 2006
    ..In this report, we describe accurate evaluation by MR imaging confirmed by histopathologic findings as well as imaging progression of this unusual case of arrhythmogenic right ventricular dysplasia...
  7. ncbi request reprint Reversible cardiomyopathy caused by administration of interferon alpha
    Aarif Y Khakoo
    Division of Cardiology, Johns Hopkins University, Baltimore, MD 21287, USA
    Nat Clin Pract Cardiovasc Med 2:53-7. 2005
    ..Physical examination findings were consistent with congestive heart failure. Laboratory studies were notable for hypothyroidism. Echocardiography revealed severe, global left-ventricular dysfunction...
  8. pmc Immunological challenges of cardiac transplantation: the need for better animal models to answer current clinical questions
    Jennifer R Wehner
    Department of Pathology, Johns Hopkins Medical Institutes, Baltimore, MD, USA
    J Clin Immunol 29:722-9. 2009
    ..First, more sensitive diagnostic tests for detection of AMR have been developed. Second, improvements in immunosuppression have made severe acute cellular rejection uncommon, but have had less effect on AMR...
  9. ncbi request reprint Antithymocyte globulin is associated with complement deposition in cardiac transplant biopsies
    William M Baldwin
    Department of Pathology, The Johns Hopkins University, Baltimore, MD 21205 2196, USA
    Hum Immunol 65:1273-80. 2004
    ..Thus prophylactic treatment with ATGAM is associated with the deposition of horse IgG and activation of complement in the transplant...
  10. ncbi request reprint Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
    Eiki Takimoto
    Division of Cardiology, Department of Medicine, Johns Hopkins Medical Institutions, Ross 835, 720 Rutland Avenue, Baltimore, Maryland 21205, USA
    Nat Med 11:214-22. 2005
    ..PDE5A inhibition may provide a new treatment strategy for cardiac hypertrophy and remodeling...
  11. ncbi request reprint Antibody and complement in transplant vasculopathy
    Jennifer Wehner
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD 21205 2196, USA
    Circ Res 100:191-203. 2007
    ..The effect of these treatment modalities on the development of coronary vasculopathy is unknown...
  12. ncbi request reprint High-resolution three-dimensional aortic magnetic resonance angiography and quantitative vessel wall characterization of different atherosclerotic stages in a rabbit model
    Henning Steen
    Division of Cardiology, Department of Medicine, Johns Hopkins University, Baltimore, Maryland, USA
    Invest Radiol 42:614-21. 2007
    ..We sought to evaluate novel magnetic resonance imaging (MRI) angiography and vessel wall sequences to visualize and quantify different morphologic stages of atherosclerosis in a Watanabe hereditary hyperlipidemic (WHHL) rabbit model...
  13. ncbi request reprint Arrhythmogenic right ventricular dysplasia: ex vivo and in vivo fat detection with black-blood MR imaging
    Ernesto Castillo
    Russell H Morgan Dept of Radiology and Radiological Sciences, Johns Hopkins University School of Medicine, 600 N Wolfe Street, MRI 143 Nelson Basement, Baltimore, MD 21287, USA
    Radiology 232:38-48. 2004
    ....
  14. pmc Impaired up-regulation of CD25 on CD4+ T cells in IFN-gamma knockout mice is associated with progression of myocarditis to heart failure
    Marina Afanasyeva
    Department of Pathology, The Johns Hopkins Medical Institutions, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Proc Natl Acad Sci U S A 102:180-5. 2005
    ..An exaggerated inflammatory response in IFN-gamma KO mice causes cardiac dysfunction, leading to dilated cardiomyopathy and heart failure...
  15. ncbi request reprint Noninvasive diagnosis of biopsy-proven cardiac amyloidosis
    Joseph E Rahman
    Division of Cardiology, Department of Medicine, Johns Hopkins Bayview Medical Center, 4940 Eastern Avenue, Baltimore, MD 21224 2780, USA
    J Am Coll Cardiol 43:410-5. 2004
    ..This study analyzed the utility of electrocardiographic (ECG) and echocardiographic findings in the diagnosis of amyloidosis proven by endomyocardial biopsy...
  16. ncbi request reprint Endovascular model of rabbit hindlimb ischemia: a platform to evaluate therapeutic angiogenesis
    Robert P Liddell
    Russell H Morgan Department of Radiology and Radiological Science, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Vasc Interv Radiol 16:991-8. 2005
    ....
  17. ncbi request reprint Increased expression of angiotensin II type 1 receptor (AGTR1) in heart transplant recipients with recurrent rejection
    Mohamad H Yamani
    Department of Cardiovascular Medicine, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Heart Lung Transplant 25:1283-9. 2006
    ..We hypothesized that recurrent acute rejection is associated with increased gene expression of AGTR1 in human heart transplantation...
  18. ncbi request reprint Acute antibody-mediated rejection of cardiac transplants
    Elaine F Reed
    Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, 1000 Veteran Avenue, Room 1335, Los Angeles, CA 90095, USA
    J Heart Lung Transplant 25:153-9. 2006
    ....
  19. ncbi request reprint Revision of the 1990 working formulation for the standardization of nomenclature in the diagnosis of heart rejection
    Susan Stewart
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 24:1710-20. 2005
    ..Technical considerations in biopsy processing are also addressed. This consensus revision of the Working Formulation was approved by the ISHLT Board of Directors in December 2004...
  20. ncbi request reprint Molecular testing in the management of cardiac transplant recipients: initial clinical experience
    Randall C Starling
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
    J Heart Lung Transplant 25:1389-95. 2006
  21. ncbi request reprint Cardiac chimerism as a mechanism for self-repair: does it happen and if so to what degree?
    Doris A Taylor
    Circulation 106:2-4. 2002
  22. ncbi request reprint Hearts from rodents exposed to intermittent hypoxia or erythropoietin are protected against ischemia-reperfusion injury
    Zheqing Cai
    McKusick Nathans Institute of Genetic Medicine, Baltimore, MD, USA
    Circulation 108:79-85. 2003
    ..Hypoxia-inducible factor 1 (HIF-1) mediates adaptive transcriptional responses to hypoxia/ischemia...
  23. ncbi request reprint Complement in transplant rejection: diagnostic and mechanistic considerations
    William M Baldwin
    Department of Pathology, Ross Research Bldg, Room 659, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD 21205, USA
    Springer Semin Immunopathol 25:181-97. 2003
    ..Therefore, the complement cascade can be activated by multiple mechanisms and various components of complement can modulate the response to transplants in different directions...
  24. ncbi request reprint Beyond C4d: other complement-related diagnostic approaches to antibody-mediated rejection
    William M Baldwin
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Transplant 4:311-8. 2004
    ..Understanding the mechanisms by which complement integrates the interactions of leukocytes, platelets and parenchymal cells offers opportunities to further refine the diagnosis of rejection...
  25. ncbi request reprint Nitric oxide regulates the heart by spatial confinement of nitric oxide synthase isoforms
    Lili A Barouch
    Department of Medicine Cardiology Division, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Nature 416:337-9. 2002
    ..Thus, NOS1 and NOS3 mediate independent, and in some cases opposite, effects on cardiac structure and function...