Luis Rodrigo

Summary

Publications

  1. pmc Osteogenesis Imperfecta with Celiac Disease and Type II Diabetes Mellitus Associated: Improvement with a Gluten-Free Diet
    Luis Rodrigo
    Gastroenterology Service, Hospital Universitario Central de Asturias HUCA, University of Oviedo, c Celestino Villamil s no 33006, Oviedo, Spain
    Case Report Med 2012:813461. 2012
  2. pmc Celiac disease and autoimmune-associated conditions
    Eugenia Lauret
    Gastroenterology Unit, Central University Hospital of Asturias, Celestino Villamil, 33006 Oviedo, Principality of Asturias, Spain
    Biomed Res Int 2013:127589. 2013
  3. pmc Clinical impact of a gluten-free diet on health-related quality of life in seven fibromyalgia syndrome patients with associated celiac disease
    Luis Rodrigo
    Gastroenterology, Central University Hospital of Asturias HUCA, Celestino Villamil, S N, 33006, Oviedo, Principality of Asturias, Spain
    BMC Gastroenterol 13:157. 2013
  4. pmc Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease
    Natalia Elguezabal
    Animal Health Department, NEIKER Instituto Vasco de Investigación y Desarrollo Agrario, Berreaga, Derio, Bizkaia, 1, 48160, Spain
    Gut Pathog 4:6. 2012
  5. ncbi request reprint Differences between pediatric and adult celiac disease
    Luis Rodrigo-Sáez
    Department of Digestive Diseases, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
    Rev Esp Enferm Dig 103:238-44. 2011
  6. doi request reprint Investigational therapies for celiac disease
    Luis Rodrigo
    Servicio de Aparato Digestivo, Hospital Universitario Central de Asturias, Oviedo, Spain
    Expert Opin Investig Drugs 18:1865-73. 2009
  7. pmc Prevalence of celiac disease in multiple sclerosis
    Luis Rodrigo
    Hospital Universitario Central de Asturias, 33006 Oviedo, Spain
    BMC Neurol 11:31. 2011
  8. ncbi request reprint Refractory iron-deficiency anemia and gluten intolerance - Response to gluten-free diet
    Luis Rodrigo Sáez
    Department of Digestive Diseases, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
    Rev Esp Enferm Dig 103:349-54. 2011
  9. ncbi request reprint [Relapsing acute pancreatitis associated with gluten enteropathy. Clinical, laboratory, and evolutive characteristics in thirty-four patients]
    L Rodrigo
    Servicios de Digestivo, Hospital Universitario Central de Asturias, Oviedo, Asturias
    Rev Esp Enferm Dig 100:746-51. 2008
  10. ncbi request reprint Extended human leukocyte antigen haplotype EH18.1 influences progression to hepatocellular carcinoma in patients with hepatitis C virus infection
    Antonio Lopez-Vazquez
    Department of Immunology, Hospital Central de Asturias, Oviedo, Spain
    J Infect Dis 189:957-63. 2004

Collaborators

Detail Information

Publications60

  1. pmc Osteogenesis Imperfecta with Celiac Disease and Type II Diabetes Mellitus Associated: Improvement with a Gluten-Free Diet
    Luis Rodrigo
    Gastroenterology Service, Hospital Universitario Central de Asturias HUCA, University of Oviedo, c Celestino Villamil s no 33006, Oviedo, Spain
    Case Report Med 2012:813461. 2012
    ..It is rewarding to search the presence of two coincidental metabolic diseases associated to OI, specially CD, because of the dramatic clinical benefit in the general found after putting on a GFD...
  2. pmc Celiac disease and autoimmune-associated conditions
    Eugenia Lauret
    Gastroenterology Unit, Central University Hospital of Asturias, Celestino Villamil, 33006 Oviedo, Principality of Asturias, Spain
    Biomed Res Int 2013:127589. 2013
    ..In several other complications and/or associated diseases, an adequate adherence to a GFD may slow down their evolution, especially if implemented during an early stage. ..
  3. pmc Clinical impact of a gluten-free diet on health-related quality of life in seven fibromyalgia syndrome patients with associated celiac disease
    Luis Rodrigo
    Gastroenterology, Central University Hospital of Asturias HUCA, Celestino Villamil, S N, 33006, Oviedo, Principality of Asturias, Spain
    BMC Gastroenterol 13:157. 2013
    ..To assess the effectiveness of a Gluten-Free Diet (GFD) in seven adult female screening-detected CD subjects, categorized as severe IBS and FMS patients...
  4. pmc Lactase persistence, NOD2 status and Mycobacterium avium subsp. paratuberculosis infection associations to Inflammatory Bowel Disease
    Natalia Elguezabal
    Animal Health Department, NEIKER Instituto Vasco de Investigación y Desarrollo Agrario, Berreaga, Derio, Bizkaia, 1, 48160, Spain
    Gut Pathog 4:6. 2012
    ..abstract:..
  5. ncbi request reprint Differences between pediatric and adult celiac disease
    Luis Rodrigo-Sáez
    Department of Digestive Diseases, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
    Rev Esp Enferm Dig 103:238-44. 2011
    ..Celiac disease (CD) is a common autoimmune condition (involves 1-2% of the general population) that develops at any age in life but manifests differently in children and adults...
  6. doi request reprint Investigational therapies for celiac disease
    Luis Rodrigo
    Servicio de Aparato Digestivo, Hospital Universitario Central de Asturias, Oviedo, Spain
    Expert Opin Investig Drugs 18:1865-73. 2009
    ..All of these therapies are in the experimental phase of development, and it is not clear if they will be approved for clinical studies. Meanwhile, a strict gluten-free diet remains a safe and effective treatment for celiac patients...
  7. pmc Prevalence of celiac disease in multiple sclerosis
    Luis Rodrigo
    Hospital Universitario Central de Asturias, 33006 Oviedo, Spain
    BMC Neurol 11:31. 2011
    ..Its mean prevalence in the general population is 1-2% worldwide. Our aim was to study the prevalence of celiac disease in a prospective series of Multiple Sclerosis (MS) patients and their first-degree relatives...
  8. ncbi request reprint Refractory iron-deficiency anemia and gluten intolerance - Response to gluten-free diet
    Luis Rodrigo Sáez
    Department of Digestive Diseases, Hospital Universitario Central de Asturias, Oviedo, Asturias, Spain
    Rev Esp Enferm Dig 103:349-54. 2011
    ..refractory iron-deficiency anemia has a multifactorial origin related to various gastrointestinal conditions, with celiac disease plus malabsorption and IBD together with isolated gluten intolerance being most common...
  9. ncbi request reprint [Relapsing acute pancreatitis associated with gluten enteropathy. Clinical, laboratory, and evolutive characteristics in thirty-four patients]
    L Rodrigo
    Servicios de Digestivo, Hospital Universitario Central de Asturias, Oviedo, Asturias
    Rev Esp Enferm Dig 100:746-51. 2008
    ..To describe the frequency and the clinical and laboratory characteristics of relapsing acute pancreatitis (AP) associated with gluten enteropathy (GE)...
  10. ncbi request reprint Extended human leukocyte antigen haplotype EH18.1 influences progression to hepatocellular carcinoma in patients with hepatitis C virus infection
    Antonio Lopez-Vazquez
    Department of Immunology, Hospital Central de Asturias, Oviedo, Spain
    J Infect Dis 189:957-63. 2004
    ..01). In conclusion, HLA-DR11 seems to be protective against the development of severe forms of infection, and the DR3/MICA-A4/B18 haplotype may be an important factor in the progression to the most severe HCV-infection status...
  11. ncbi request reprint Association of MHC class I related gene B (MICB) to celiac disease
    Segundo Gonzalez
    Department of Functional Biology, University of Oviedo, Spain
    Am J Gastroenterol 99:676-80. 2004
    ..Celiac disease (CD) is an enteropathic disorder characterized by strong association with HLA-DQ2. Our aim was to investigate whether MICB, a gene located in the MHC class I region, may contribute to CD susceptibility...
  12. ncbi request reprint Protective effect of the HLA-Bw4I80 epitope and the killer cell immunoglobulin-like receptor 3DS1 gene against the development of hepatocellular carcinoma in patients with hepatitis C virus infection
    Antonio Lopez-Vazquez
    Department of Immunology, Hospital Universitario Central de Asturias, Oviedo, Spain
    J Infect Dis 192:162-5. 2005
    ..Moreover, these associations were not independent of each other--the KIR3DS1/Bw4I80 genotype clearly was also more frequent in HCV carriers (odds ratio, 24.22)...
  13. ncbi request reprint MHC class I region plays a role in the development of diverse clinical forms of celiac disease in a Saharawi population
    Antonio Lopez-Vazquez
    Department of Immunology, Hospital Universitario Central de Asturias, Oviedo, Spain
    Am J Gastroenterol 99:662-7. 2004
    ..The aim of this study was to investigate the association of MHC genes in the development of celiac disease (CD) and its diverse clinical forms in a Saharawi population...
  14. ncbi request reprint MHC class I chain-related gene A transmembrane polymorphism modulates the extension of ulcerative colitis
    Juan Luis Fdez-Morera
    Department of Immunology, Hospital Universitario Central de Asturias, Oviedo, Spain
    Hum Immunol 64:816-22. 2003
    ..These results are in agreement with other studies that suggest a similar role of such alleles in other diseases, such as insulin-dependent diabetes mellitus and celiac disease...
  15. doi request reprint Annual incidence of hepatocellular carcinoma among patients with alcoholic cirrhosis and identification of risk groups
    Alejo Mancebo
    Liver Unit, Hospital Universitario Central de Asturias, Oviedo, Spain Department of Gastroenterology and Hepatology, Hospital Universitario Central de Asturias, Oviedo, Spain
    Clin Gastroenterol Hepatol 11:95-101. 2013
    ..5% per year. We performed a prospective study to determine the incidence of HCC among patients with alcoholic cirrhosis and to identify risk factors...
  16. ncbi request reprint MHC class I chain-related gene B promoter polymorphisms and celiac disease
    Sandra Rodriguez-Rodero
    Department of Functional Biology, University of Oviedo, Spain
    Hum Immunol 67:208-14. 2006
    ..4% CD patients vs 45.3% healthy controls; p(c) < 0.0001; OR = 4.64; CI 95% = 2.64-8.16). Both MICB*008 and MICB*002 alleles were found as part of the CD susceptibility extended haplotypes B8/DR3/DQ2, B18/DR3/DQ2, and DR4/DQ8...
  17. ncbi request reprint High serum tumor necrosis factor-alpha levels are associated with lack of response to infliximab in fistulizing Crohn's disease
    Jesus Martinez-Borra
    Department of Immunology and Gastroenterology, Hospital Central de Asturias, Oviedo, Spain
    Am J Gastroenterol 97:2350-6. 2002
    ..We investigated the effect of infliximab on circulating cytokines and acute phase proteins in patients with fistulas to determine the clinical response to anti-TNF-alpha...
  18. doi request reprint Adult patients with eosinophilic esophagitis do not show an increased frequency of the HLA-DQ2/DQ8 genotypes predisposing to celiac disease
    Alfredo J Lucendo
    Department of Gastroenterology, Hospital General de Tomelloso, Vereda de Socuéllamos, S N, 13700, Tomelloso, Ciudad Real, Spain
    Dig Dis Sci 56:1107-11. 2011
    ..Recent articles have described patients that share eosinophilic esophagitis (EoE) and celiac disease (CD) suggesting a true relationship between both diseases...
  19. ncbi request reprint Comparison of six human anti-transglutaminase ELISA-tests in the diagnosis of celiac disease in the Saharawi population
    Eloy Fernández
    Biochemistry Service, Hospital de Cabuenes, Gijon, Asturias, Spain
    World J Gastroenterol 11:3762-6. 2005
    ..Celiac disease (CD) is an enteropathic disorder very prevalent in Saharawi people. Our aim was to investigate the diagnostic accuracy of six human tissue transglutaminase (tTG) based ELISA tests in Saharawi CD patients...
  20. ncbi request reprint Transcriptional regulation of MICA and MICB: a novel polymorphism in MICB promoter alters transcriptional regulation by Sp1
    Sandra Rodriguez-Rodero
    Unidad de Histocompatibilidad y Transplantes, Hospital Universitario Central de Asturias Oviedo, Oviedo, Spain
    Eur J Immunol 37:1938-53. 2007
    ....
  21. ncbi request reprint MICB typing by PCR amplification with sequence specific primers
    Segundo Gonzalez
    Department of Functional Biology, University of Oviedo, Julián Clavería sn, 33006 Oviedo, Spain
    Immunogenetics 54:850-5. 2003
    ..Thus, the linkage disequilibrium with MICA and HLA-B suggests that MICB is a potential candidate for those diseases classically associated with HLA class I alleles...
  22. ncbi request reprint Diversity of Killer Cell Immunoglobulin-Like Receptor (KIR) Genotypes and KIR2DL2/3 Variants in HCV Treatment Outcome
    Jose Ramon Vidal-Castiñeira
    Immunology Service, Hospital Universitario Central de Asturias, Oviedo, Spain
    PLoS ONE 9:e99426. 2014
    ..The study of KIR receptors may be a powerful tool for predicting the combined treatment response in patients with chronic HCV infection in association with the determination of IFNL3 polymorphism. ..
  23. ncbi request reprint The allele MICB 0050204, over-represented in the Caucasian population, has an additional exon resulting from a new splice junction sequence
    Jesus Martinez-Borra
    Department of Immunology, Hospital Universitario Central de Asturias, Oviedo, Spain
    Hum Immunol 68:705-7. 2007
    ..This new exon contains a premature stop codon and therefore the transcript does not produce a functional protein...
  24. doi request reprint Immune-dependent and independent antitumor activity of GM-CSF aberrantly expressed by mouse and human colorectal tumors
    Rocio G Urdinguio
    Cancer Epigenetics Laboratory, HUCA, Institute of Oncology of Asturias IUOPA, Universidad de Oviedo, Oviedo, Spain
    Cancer Res 73:395-405. 2013
    ..These data suggest that expression of GM-CSF and its receptor subunits by colon tumors may be a useful marker for prognosis as well as for patient stratification in cancer immunotherapy...
  25. doi request reprint Soluble MHC class I chain-related protein B serum levels correlate with disease activity in relapsing-remitting multiple sclerosis
    Juan Luis Fernandez-Morera
    Unidad de Histocompatibilidad y Transplantes, Hospital Universitario Central de Asturias, Oviedo, Spain
    Hum Immunol 69:235-40. 2008
    ..Elevated soluble MICB levels exist in serum of multiple sclerosis patients related with disease activity. This may contribute to the modulation of immune response activity during relapses...
  26. doi request reprint Epithelial-mesenchymal transition induces an antitumor immune response mediated by NKG2D receptor
    Alejandro Lopez-Soto
    Departamento de Biologia Funcional, Universidad de Oviedo, Instituto Universitario de Oncologia del Principado de Asturias, 33006 Oviedo, Spain
    J Immunol 190:4408-19. 2013
    ..Overall, our findings indicate that EMT is a relevant checkpoint in the control of tumor progression through NKG2D-mediated immune responses...
  27. ncbi request reprint TNF-alpha -308A promoter polymorphism is associated with enhanced TNF-alpha production and inflammatory activity in Crohn's patients with fistulizing disease
    Segundo Gonzalez
    Department of Functional Biology, University of Oviedo, Oviedo, Spain
    Am J Gastroenterol 98:1101-6. 2003
    ..The aim of this study was to investigate the effect of TNF-alpha promoter polymorphism at -308 on the susceptibility and phenotypic expression of fistulizing CD...
  28. ncbi request reprint Time trends and impact of upper and lower gastrointestinal bleeding and perforation in clinical practice
    Angel Lanas
    Servicio de Aparato Digestivo, Hospital Clinico, Universidad de Zaragoza, Zaragoza, Spain
    Am J Gastroenterol 104:1633-41. 2009
    ....
  29. doi request reprint Second-line therapy with levofloxacin after failure of treatment to eradicate helicobacter pylori infection: time trends in a Spanish Multicenter Study of 1000 patients
    Javier P Gisbert
    Gastroenterology Unit, La Princesa, Instituto de Investigación Sanitaria Princesa IP y, Centro de Investigacion Biomedica en Red de Enfermedades Hepaticas y Digestivas CIBERehd, Madrid, Spain
    J Clin Gastroenterol 47:130-5. 2013
    ..Second-line bismuth-containing quadruple therapy is complex and frequently induces adverse effects. A triple rescue regimen containing levofloxacin is a potential alternative; however, resistance to quinolones is rapidly increasing...
  30. doi request reprint [Gluten-related disorders and demyelinating diseases]
    Carlos Hernández-Lahoz
    Clínica de Neurología, Oviedo, Spain
    Med Clin (Barc) 140:314-9. 2013
    ..Treatment with a gluten-free diet can provide considerable benefits to the patients having both a gluten-related disorder and one of these 2 demyelinating diseases of the central nervous system...
  31. pmc NKG2D expression in CD4+ T lymphocytes as a marker of senescence in the aged immune system
    Rebeca Alonso-Arias
    Histocompatibility Unit, Immunology Department, Hospital Universitario Central de Asturias, Oviedo, Spain
    Age (Dordr) 33:591-605. 2011
    ..In conclusion, CD4+ NKG2D+ represent a subset of highly differentiated T cells which characterizes the senescence of the immune system...
  32. doi request reprint Autoantibodies against MHC class I polypeptide-related sequence A are associated with increased risk of concomitant autoimmune diseases in celiac patients
    Antonio Lopez-Vazquez
    Department of Immunology, Hospital Universitario Central de Asturias, Oviedo 33006, Spain
    BMC Med 12:34. 2014
    ..The aim of this study was to investigate anti-MICA antibody formation in patients with celiac disease and its association with other autoimmune processes...
  33. doi request reprint Usefulness of an intensive bowel cleansing strategy for repeat colonoscopy after preparation failure
    Mercedes Ibañez
    Endoscopy Unit, Department of Gastroenterology, Asturias Central University Hospital, Oviedo, Spain
    Dis Colon Rectum 54:1578-84. 2011
    ..No consensus exists regarding the optimal bowel preparation regimen for patients with poor bowel cleansing at a previous colonoscopy...
  34. doi request reprint CD8dim and NKG2D expression defines related subsets of CD4+ T cells in HIV-infected patients with worse prognostic factors
    Rebeca Alonso-Arias
    Histocompatibility Unit, Immunology Department Hospital Universitario Central de Asturias, Oviedo, Spain
    J Acquir Immune Defic Syndr 51:390-8. 2009
    ..Their common ontogenic origin and oligoclonality, possibly due to repeated encounters with the same antigen, could result in a limitation of the repertoire of responder cells and in a worse prognosis of HIV infection...
  35. doi request reprint A predictive model of treatment outcome in patients with chronic HCV infection using IL28B and PD-1 genotyping
    Jose Ramon Vidal-Castiñeira
    Immunology Service, Hospital Universitario Central de Asturias, Oviedo, Spain
    J Hepatol 56:1230-8. 2012
    ..The aim of this study was to analyse the effect of several single nucleotide polymorphisms of PD-1 gene and several previously associated factors (IL28B and KIR receptors) on treatment responses...
  36. ncbi request reprint Acute hepatitis C in Spain: a retrospective study of 131 cases
    Ramón Pérez-Alvarez
    Hospital Universitario Central de Asturias, Calle Celestino Villamil s n 33006, Oviedo, Spain
    Rev Esp Enferm Dig 104:21-8. 2012
    ..We have conducted a retrospective study to determine the epidemiological and biochemical aspects, the genotypes, the spontaneous clearance of HCV (SVC), and the treatment responses in patients with AHC...
  37. doi request reprint Clinical patterns and outcomes of ischaemic colitis: results of the Working Group for the Study of Ischaemic Colitis in Spain (CIE study)
    Miguel A Montoro
    Department of Gastroenterology, Hospital San Jorge, Huesca, Spain
    Scand J Gastroenterol 46:236-46. 2011
    ..We performed such a study to evaluate the clinical presentation, outcome, and mortality as well as clinical variables associated with poor prognosis...
  38. ncbi request reprint Quality of life in patients with functional dyspepsia: a prospective 1-year follow-up study in Spanish patients
    Ana Gutierrez
    Gastroenterology Unit, Hospital Virgen Blanca, Leon, Spain
    Eur J Gastroenterol Hepatol 15:1175-81. 2003
    ..The natural history of functional dyspepsia is not well known. We prospectively assess the quality of life and severity of symptoms in a group of Spanish patients with functional dyspepsia...
  39. ncbi request reprint Prospective analysis of risk factors for hepatocellular carcinoma in patients with liver cirrhosis
    Rosario F Velázquez
    Department of Gastroenterology, Hospital Central de Asturias, Oviedo, Spain Department of Gastroenterology, Hospital de Cabuenes, Gijon, Spain
    Hepatology 37:520-7. 2003
    ..We believe this score can be useful in establishing a subset of cirrhotic patients in whom a surveillance program for early detection of HCC could be unjustified...
  40. doi request reprint T-cell profiling and the immunodiagnosis of latent tuberculosis infection in patients with inflammatory bowel disease
    Miguel Arias-Guillén
    Department of Respiratory Medicine, Instituto Nacional de Silicosis, Hospital Universitario Central de Asturias, Oviedo, Spain Department of Digestive Diseases, Hospital Universitario Central de Asturias, Oviedo, Spain Department of Microbiology, Mycobacterial Reference Unit, Hospital Universitario Central de Asturias, Oviedo, Spain Department of Respiratory Medicine, Hospital Arnau de Villanova, Valencia, Spain Division of Pulmonary and Critical Care Medicine and Mayo Clinic Center for Tuberculosis, Mayo Clinic, Rochester, Minnesota Department of Radiology, Hospital Universitario Central de Asturias, Oviedo and Oficina de Investigación Biosanitaria, Hospital Universitario Central de Asturias, Oviedo, Spain
    Inflamm Bowel Dis 20:329-38. 2014
    ..The influence of peripheral T-cell subset counts on the results also remain unclear...
  41. doi request reprint A DNA methylation signature associated with aberrant promoter DNA hypermethylation of DNMT3B in human colorectal cancer
    Covadonga Huidobro
    Cancer Epigenetics Laboratory, Instituto Universitario de Oncologia del Principado de Asturias, HUCA, Universidad de Oviedo, Oviedo, Spain
    Eur J Cancer 48:2270-81. 2012
    ..Our results show a new molecular mechanism of aberrant DNMT3B regulation in colon cancer and suggest that its expression is associated with the methylation of constitutively hypermethylated promoters in the healthy colon...
  42. ncbi request reprint Celiac disease
    Luis Rodrigo
    Gastroenterology Service, Hospital Universitario Central de Asturias, c Celestino Villamil s n 33 006 Oviedo, Spain
    World J Gastroenterol 12:6585-93. 2006
    ..Treatment of CD dictates a strict, life-long gluten-free diet, which results in remission for most individuals, although its effect on some associated extraintestinal manifestations remains to be established...
  43. doi request reprint Kaposi's sarcoma: an opportunistic infection by human herpesvirus-8 in ulcerative colitis
    María Rodríguez-Peláez
    Department of Gastroenterology, Hospital Universitario Central de Asturias, 33006 Oviedo, Asturias, Spain
    J Crohns Colitis 4:586-90. 2010
    ..Human herpesvirus-8 infection should be recognized as a possible opportunistic infection in patients with inflammatory bowel disease...
  44. ncbi request reprint High variability of HLA-B27 alleles in ankylosing spondylitis and related spondyloarthropathies in the population of northern Spain
    Segundo Gonzalez
    Functional Biology Department S G, University of Oviedo, Oviedo, Spain
    Hum Immunol 63:673-6. 2002
    ..B*2713 was identified in a healthy control family. B*2713 has not been reported to be represented in either ethnic group. Thus, this population shows higher levels of B27 diversity than other Caucasian groups...
  45. doi request reprint Gastric endoscopic submucosal dissection assisted by a new traction method: the clip-band technique. A feasibility study in a porcine model (with video)
    Adolfo Parra-Blanco
    Endoscopy Unit, Department of Gastroenterology, University Hospital of Canary Islands, Tenerife, Spain
    Gastrointest Endosc 74:1137-41. 2011
    ..Several traction methods have been proposed to facilitate submucosal dissection, but they are usually not widely available or are difficult to apply...
  46. ncbi request reprint Serum concentration of alpha-1 antitrypsin is significantly higher in colorectal cancer patients than in healthy controls
    Sergio Pérez-Holanda
    General Surgery Department, Hospital Valle del Nalon, 33920 Langreo, Principality of Asturias, Spain
    BMC Cancer 14:355. 2014
    ..The present study compares AAT serum concentrations and gene frequencies between a group of CRC patients and a control group of healthy unrelated people (HUP)...
  47. ncbi request reprint Thiopurine methyltransferase (TPMT) activity and adverse effects of azathioprine in inflammatory bowel disease: long-term follow-up study of 394 patients
    Javier P Gisbert
    Gastroenterology Unit, Hospital Universitario de la Princesa, Universidad Autonoma, Madrid, Spain
    Am J Gastroenterol 101:2769-76. 2006
    ....
  48. ncbi request reprint Autoantibodies to Golgi proteins in hepatocellular carcinoma: case report and literature review
    Lourdes Mozo
    Department of Immunology, Hospital Central de Asturias, Julian Claveria s n, 33006 Oviedo, Spain
    Eur J Gastroenterol Hepatol 14:771-4. 2002
    ..5% (two cases out of 36). The mechanism involved in the appearance of anti-Golgi antibodies in HCC is discussed, along with a review of the reported cases of liver diseases associated with the appearance of Golgi autoantibodies...
  49. ncbi request reprint [Peritoneal tuberculosis due to Mycobacterium bovis in a cirrhotic patient]
    Patricia García-González
    Departamento de Digestivo, Hospital Universitario Central de Asturias, Oviedo, Espana
    Gastroenterol Hepatol 32:495-8. 2009
    ..We present a patient with cirrhosis who developed ascites caused by an exceptional infection in our setting...
  50. ncbi request reprint A nationwide study of mortality associated with hospital admission due to severe gastrointestinal events and those associated with nonsteroidal antiinflammatory drug use
    Angel Lanas
    Servicio de Aparato Digestivo, Hospital Clinico Zaragoza, Zaragoza, Spain
    Am J Gastroenterol 100:1685-93. 2005
    ..The worst outcome of gastrointestinal complications is death. Data regarding those associated with nonsteroidal antiinflammatory drug (NSAID) or aspirin use are scarce...
  51. pmc Endoscopic resection techniques and ablative therapies for Barrett's neoplasia
    Jacobo Ortiz-Fernández-Sordo
    Jacobo Ortiz Fernández Sordo, Adolfo Parra Blanco, Endoscopy Unit, Department of Gastroenterology, Central University Hospital of Asturias, Celestino Villamil s n, Oviedo 33006, Asturias, Spain
    World J Gastrointest Endosc 3:171-82. 2011
    ....
  52. ncbi request reprint [Increased prevalence of celiac disease in first and second-grade relatives. A report of a family with 19 studied members]
    L Rodrigo
    Servicio de Digestivo, Hospital Universitario Central de Asturias, Oviedo, Spain
    Rev Esp Enferm Dig 99:149-55. 2007
    ..As a result, this condition is clearly familial, and mainly associated with HLA class II markers...
  53. ncbi request reprint Usefulness of duodenal biopsy during routine upper gastrointestinal endoscopy for diagnosis of celiac disease
    S Riestra
    Gastroenterology Section, Hospital Central de Asturias, Oviedo, Spain
    World J Gastroenterol 12:5028-32. 2006
    ..To describe the trend in duodenal biopsy performance during routine upper gastrointestinal endoscopy in an adult Spanish population, and to analyze its value for the diagnosis of celiac disease in clinical practice...
  54. ncbi request reprint Celiac disease (CD), ulcerative colitis (UC), and primary sclerosing cholangitis (PSC) in one patient: a family study
    V Cadahia
    Service of Digestive Diseases, Hospital Universitario Central de Asturias, Oviedo, Spain
    Rev Esp Enferm Dig 97:907-13. 2005
    ..A family study was made, and both parents were found to be affected with silent CD. All were DQ2 (+). In relation to the case and family study, we provide a series of comments related to CD and its complications...
  55. ncbi request reprint Nodular regenerative hyperplasia of the liver in a patient with celiac disease
    S Riestra
    Digestive Unit, Hospital Valle del Nalon, Asturias, Spain
    J Clin Gastroenterol 33:323-6. 2001
    ..We discuss the different types of liver disorders associated with celiac disease and the possible relation between nodular regenerative hyperplasia and celiac disease, based on immunologic mechanisms...
  56. pmc MHC class I chain related gene A (MICA) modulates the development of coeliac disease in patients with the high risk heterodimer DQA1*0501/DQB1*0201
    A Lopez-Vazquez
    Department of Immunology, Hospital Central de Asturias, Oviedo, Spain
    Gut 50:336-40. 2002
    ..The aim of this study was to investigate whether other candidate genes modify the risk of developing different clinical forms of CD...
  57. ncbi request reprint Diverse clinical presentations of celiac disease in the same family
    L Rodrigo
    Service of Digestive Diseases and Immunology, Hospital Central de Asturias, Oviedo, Spain
    Rev Esp Enferm Dig 96:612-6; 416-9. 2004
    ..Overall family involvement was 11.8% (4/14). We wish to emphasize the need to perform extended family studies when diagnosing a case of CD, since risk is not restricted to only first-degree relatives...