J P Rodrigo

Summary

Publications

  1. ncbi request reprint [A giant bilateral concha bullosa causing nasal obstruction]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital de Leon, Leon, Espana
    Acta Otorrinolaringol Esp 50:490-2. 1999
  2. ncbi request reprint EMS1 gene amplification correlates with poor prognosis in squamous cell carcinomas of the head and neck
    J P Rodrigo
    Department of Otolaryngology Head and Neck Surgery, Hospital Central de Asturias, University of Oviedo, Instituto Universitario de Oncologia, Spain
    Clin Cancer Res 6:3177-82. 2000
  3. ncbi request reprint [Molecular changes in epidermoid carcinoma of the oropharynx]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital Central de Asturias
    Acta Otorrinolaringol Esp 52:24-31. 2001
  4. ncbi request reprint P53 allelic loss and outcome in patients with squamous cell carcinoma of the head and neck
    J P Rodrigo
    Department of Otolaryngology, Instituto Universitario de Oncologia del Principado de Asturias, Hospital Central de Asturias, Universidad de Oviedo, Spain
    Eur Arch Otorhinolaryngol 258:255-8. 2001
  5. ncbi request reprint [CCND1 oncogene amplification and cellular DNA content in squamous cell carcinomas of the head and neck]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital Central de Asturias, Instituto Universitario de Oncologia del Principado de Asturias, Oviedo
    Acta Otorrinolaringol Esp 52:539-43. 2001
  6. ncbi request reprint [Inactivation of p53 and amplification of cyclin D1 in squamous cell carcinomas of the head and neck]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital Central de Asturias, Instituto Universitario de Oncologia, Universidad de Oviedo, Oviedo, Asturias
    Acta Otorrinolaringol Esp 53:225-32. 2002
  7. ncbi request reprint Variability of genetic alterations in different sites of head and neck cancer
    J P Rodrigo
    Department of Otolaryngology, Hospital Central de Asturias, University of Oviedo, Instituto Universitario de Oncologia, Oviedo, Spain
    Laryngoscope 111:1297-301. 2001
  8. doi request reprint Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas
    J P Rodrigo
    Instituto Universitario de Oncologia del Principado de Asturias, Hospital Universitario Central de Asturias, Universidad de Oviedo, Oviedo, Spain
    J Pathol 217:516-23. 2009
  9. doi request reprint The relation between hypoxia-inducible factor (HIF)-1alpha expression with p53 expression and outcome in surgically treated supraglottic laryngeal cancer
    R Cabanillas
    Servicio de Otorrinolaringologia, Hospital Universitario Central de Asturias, Oviedo, Spain
    J Surg Oncol 99:373-8. 2009
  10. ncbi request reprint [Efficacy of postoperative radiation therapy for squamous cell carcinoma of the head and neck: results of a prospective randomised clinical trial]
    J P Rodrigo
    Servicio de Otorrinolaringologia, Hospital Universitario Central de Asturias, Oviedo, Asturias
    Acta Otorrinolaringol Esp 55:415-9. 2004

Collaborators

  • C Suarez Nieto
  • G Sequeiros Santiago
  • E Coto
  • C Ortega
  • J P Rodrigo Tapia
  • R Cabanillas
  • L A García González
  • M V González Meana
  • A Martínez Ferreras
  • I Alvarez Alvarez
  • J Garcia Pedrero
  • M D Chiara
  • A Astudillo
  • P Secades
  • V Franco Gutiérrez
  • C Suarez
  • C Alvarez Marcos
  • F Dominguez Iglesias
  • P Sánchez Lazo
  • S Ramos
  • J A Martínez Sánchez
  • C S Nieto
  • M P Cuesta Albalad
  • J L Llorente
  • P Ortega
  • R Cabanillas Farpón
  • M F Fresno
  • F Núñez Batalla
  • J M García Pedrero
  • V Alvarez
  • J L Díaz Villarig
  • C Casas Rubio
  • A Blanco Mercadé

Detail Information

Publications23

  1. ncbi request reprint [A giant bilateral concha bullosa causing nasal obstruction]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital de Leon, Leon, Espana
    Acta Otorrinolaringol Esp 50:490-2. 1999
    ..We present an uncommon case of massive bilateral concha bullosa that produced complete obstruction of the left nasal cavity and partial obstruction of the right nasal cavity...
  2. ncbi request reprint EMS1 gene amplification correlates with poor prognosis in squamous cell carcinomas of the head and neck
    J P Rodrigo
    Department of Otolaryngology Head and Neck Surgery, Hospital Central de Asturias, University of Oviedo, Instituto Universitario de Oncologia, Spain
    Clin Cancer Res 6:3177-82. 2000
    ..The prognostic significance previously attributed to CCND1 amplification may be attributable to its frequent coamplification with EMS1...
  3. ncbi request reprint [Molecular changes in epidermoid carcinoma of the oropharynx]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital Central de Asturias
    Acta Otorrinolaringol Esp 52:24-31. 2001
    ..Nine (69%) of the 13 analyzed cases were aneuploid. The only alteration with a prognostic significance was 11q13 amplification that showed a tendency to be associated with a higher frequency of nodal metastases and tumor recurrence...
  4. ncbi request reprint P53 allelic loss and outcome in patients with squamous cell carcinoma of the head and neck
    J P Rodrigo
    Department of Otolaryngology, Instituto Universitario de Oncologia del Principado de Asturias, Hospital Central de Asturias, Universidad de Oviedo, Spain
    Eur Arch Otorhinolaryngol 258:255-8. 2001
    ..98). These data suggest that although LOH at the p53 locus is common in SCCHN, this finding is of little clinical significance...
  5. ncbi request reprint [CCND1 oncogene amplification and cellular DNA content in squamous cell carcinomas of the head and neck]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital Central de Asturias, Instituto Universitario de Oncologia del Principado de Asturias, Oviedo
    Acta Otorrinolaringol Esp 52:539-43. 2001
    ..36). We conclude that CCND1 amplification is not associated to a higher incidence of chromosomal aberrations in squamous cell carcinomas of the head and neck...
  6. ncbi request reprint [Inactivation of p53 and amplification of cyclin D1 in squamous cell carcinomas of the head and neck]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital Central de Asturias, Instituto Universitario de Oncologia, Universidad de Oviedo, Oviedo, Asturias
    Acta Otorrinolaringol Esp 53:225-32. 2002
    ..The combined analysis of these abnormalities seems to be more informative than either of them individually and may have a prognostic value in these carcinomas...
  7. ncbi request reprint Variability of genetic alterations in different sites of head and neck cancer
    J P Rodrigo
    Department of Otolaryngology, Hospital Central de Asturias, University of Oviedo, Instituto Universitario de Oncologia, Oviedo, Spain
    Laryngoscope 111:1297-301. 2001
    ..The objective of this study is to compare the genetic alterations in three different sites of the head and neck (larynx, oropharynx, and hypopharynx)...
  8. doi request reprint Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas
    J P Rodrigo
    Instituto Universitario de Oncologia del Principado de Asturias, Hospital Universitario Central de Asturias, Universidad de Oviedo, Oviedo, Spain
    J Pathol 217:516-23. 2009
    ..018). Taken together, these data indicate that CTTN may serve as a valuable biomarker to identify patients with laryngeal tumours at high risk of recurrence and poor outcome...
  9. doi request reprint The relation between hypoxia-inducible factor (HIF)-1alpha expression with p53 expression and outcome in surgically treated supraglottic laryngeal cancer
    R Cabanillas
    Servicio de Otorrinolaringologia, Hospital Universitario Central de Asturias, Oviedo, Spain
    J Surg Oncol 99:373-8. 2009
    ....
  10. ncbi request reprint [Efficacy of postoperative radiation therapy for squamous cell carcinoma of the head and neck: results of a prospective randomised clinical trial]
    J P Rodrigo
    Servicio de Otorrinolaringologia, Hospital Universitario Central de Asturias, Oviedo, Asturias
    Acta Otorrinolaringol Esp 55:415-9. 2004
    ....
  11. ncbi request reprint [Functional outcomes of transoral laser surgery of supraglottic carcinoma]
    R Cabanillas
    Servicio de Otorrinolaringologia, Hospital Universitario Central de Asturias, Universidad de Oviedo, Instituto Universitario de Oncologia del Principado de Asturias, Oviedo, Asturias
    Acta Otorrinolaringol Esp 56:156-60. 2005
    ..To analyse the functional outcome of patients with supraglottic carcinomas treated by transoral laser surgery...
  12. ncbi request reprint [Orthotopic murine model of head and neck squamous cell carcinoma]
    R Cabanillas
    Servicio de Otorrinolaringologia, Hospital Universitario Central de Asturias, Universidad de Oviedo, Instituto Universitario de Oncologia del Principado de Asturias, Oviedo
    Acta Otorrinolaringol Esp 56:89-95. 2005
    ..This model should facilitate our understanding of the molecular mechanisms of tumorigenicity and progression of these tumors, as well as the evaluation of novel therapies...
  13. ncbi request reprint [The relationship between human papillomavirus and cyclin D1 gene amplification in squamous cell carcinomas of the head and neck]
    J P Rodrigo Tapia
    Servicio de Otorrinolaringologia, Hospital Universitario Central de Asturias, Oviedo, Asturias
    Acta Otorrinolaringol Esp 56:428-33. 2005
    ..The objective of this paper is to establish the relationship between the presence of human papillomavirus (HPV) gene sequences and the development of CCND1 gene amplification in these tumours...
  14. ncbi request reprint [Relationship between the integration of human papillomavirus and loss of heterozygosity of the P53 gene in squamous cell carcinomas of the head and neck]
    A Martínez Ferreras
    Servicio de ORL, Hospital Central de Asturias, Instituto Universitario de Oncologia del Principado de Asturias
    Acta Otorrinolaringol Esp 52:546-52. 2001
    ..No correlation was found between both events and they were not related to clinical factors neither the prognosis. Consequently, HPV integration and loss of heterozygosity of P53 seem to act independently in the genesis of these tumours...
  15. ncbi request reprint [DNA extraction using Chelex resin for oncogenic amplification analysis in head and neck tumours]
    L A García González
    Servicio de ORL, Hospital Carmen y Severo Ochoa, Asturias
    Acta Otorrinolaringol Esp 55:139-44. 2004
    ..The results show that proteinase K-Chelex 100 procedure is as efficient as the phenol-chloroform one...
  16. ncbi request reprint [Epidermal growth factor receptor gene amplification and E-cadherin expression in head and neck carcinomas]
    J P Rodrigo Tapia
    Servicio de Otorrinolaringologia, Hospital Central de Asturias, Instituto Universitario de Oncologia del Principado de Asturias, Universidad de Oviedo, Asturias
    Acta Otorrinolaringol Esp 55:482-7. 2004
    ..The aim of this study is to confirm whether EGFR amplification is related to E-cadherin expression in head and neck squamous cell carcinomas...
  17. ncbi request reprint Expression of E-cadherin in squamous cell carcinomas of the supraglottic larynx with correlations to clinicopathological features
    J P Rodrigo
    Department of Otolaryngology, Hospital Central de Austurias, Universidad de Oviedo, Instituto Universitario de Oncología de Principado de Asturias, Oviedo, Asturias, Spain
    Eur J Cancer 38:1059-64. 2002
    ..Determination of E-cadherin expression levels might be useful in identifying patients with clinically negative lymph nodes who are at risk of occult metastases, allowing more effective treatment strategies to be implemented...
  18. ncbi request reprint [CCND1 gene amplification in the adenoid cystic carcinoma of the minor salivary glands]
    G Sequeiros Santiago
    Servicio de ORL, Hospital Central de Asturias, Oviedo
    Acta Otorrinolaringol Esp 55:88-92. 2004
    ..The aim of this study is to determine the amplification of the CCND1 gene in the ACC of the minor salivary glands...
  19. ncbi request reprint [Prognostic significance of the expression of adhesion molecules E-cadherin, Cd44s and CD44V6 in supraglottic squamous carcinoma]
    J P Rodrigo Tapia
    Servicio de ORL, Hospital Central de Asturias, Oviedo
    Acta Otorrinolaringol Esp 53:745-51. 2002
    ..To establish the prognostic significance of the expression of adhesion molecules E-cadherin, CD44s and CD44v6 in squamous cell carcinomas of the supraglottic larynx...
  20. ncbi request reprint [Angiomyoma of the retropharyngeal space]
    A Martínez Ferreras
    Servicio de Otorrinolaringologia, Hospital Central de Asturias, Oviedo
    Acta Otorrinolaringol Esp 55:488-90. 2004
    ..The treatment is excision of the tumour and recurrence is exceptional...
  21. ncbi request reprint [Anaplastic thyroid carcinoma. Our experience]
    G Sequeiros Santiago
    Servicio de ORL, Hospital Central de Asturias, Oviedo
    Acta Otorrinolaringol Esp 55:424-9. 2004
    ..Anaplastic thyroid cancer ranks among the most lethal of all known human malignancies, and remains almost uniformly fatal. It represents approximately 1% of all thyroid carcinomas...
  22. ncbi request reprint [Prognostic factors in adenoid cystic carcinoma of salivary glands]
    G Sequeiros Santiago
    Servicio de ORL Hospital Universitario Central de Asturias, Instituto Universitario de Oncologia, Universidad de Oviedo, Oviedo, Asturias
    Acta Otorrinolaringol Esp 56:361-7. 2005
    ..The aim of the present study is to show our experience in the management of this tumor and the relationship of different clinico-pathological parameters with its prognosis...
  23. ncbi request reprint [Lateral crural "J" flap repair to correct nasal valve collapse]
    V Franco Gutiérrez
    Servicio de Otorrinolaringología del Hospital Universitario Central de Asturias, Oviedo, Asturias
    Acta Otorrinolaringol Esp 57:350-4. 2006
    ..This technique is based on a new view of the structural etiology of nasal valve collapse and it offers excellent functional and aesthetic outcomes...