Epidemiology of Leishmania donovani infection in high-transmission foci in NepalSuman Rijal
BP Koirala Institute of Health Sciences, Ghopa, Dharan, Nepal
Trop Med Int Health 15:21-8. 2010
..We report data on prevalence rates of Leishmania donovani infection in ten communities in East Nepal...
Clinical risk factors for therapeutic failure in kala-azar patients treated with pentavalent antimonials in NepalS Rijal
Department of Internal Medicine, B P Koirala Institute of Health Sciences, Dharan 056700, Nepal
Trans R Soc Trop Med Hyg 104:225-9. 2010
..1), interruption of treatment (OR=4.3) and ambulatory treatment (OR=10.2). Early diagnosis and supervised treatment is of paramount importance to prevent treatment failures within the control programme...
Evaluation of a urinary antigen-based latex agglutination test in the diagnosis of kala-azar in eastern NepalS Rijal
B P Koirala Institute of Health Sciences, Dharan, Nepal
Trop Med Int Health 9:724-9. 2004
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The economic burden of visceral leishmaniasis for households in NepalS Rijal
Department of Medicine, B P Koirala Institute of Health Sciences, Dharan, Nepal
Trans R Soc Trop Med Hyg 100:838-41. 2006
..Direct costs consisted of 53% of the total cost, with 75% of this cost incurred before the patients actually received any treatment for VL. This study demonstrates how VL can lead to catastrophic expenditure for affected households...
Treatment of visceral leishmaniasis in south-eastern Nepal: decreasing efficacy of sodium stibogluconate and need for a policy to limit further declineS Rijal
B. P. Koirala Institute of Health Sciences, Dharan, Nepal
Trans R Soc Trop Med Hyg 97:350-4. 2003
..These findings indicate that the spread of resistance to antimonials is already taking place in Nepal and that a policy to control further spread should be urgently implemented...
Comparative study of kala-azar vector control measures in eastern NepalM L Das
Department of Microbiology, B P Koirala Institute of Health Sciences, Dharan, Nepal
Acta Trop 113:162-6. 2010
..Hence, IRS was found most effective control measure to decrease vector density. LLINs were also found effective and can be considered as a promising alternative vector control tool in VL elimination initiative...
Sodium stibogluconate cardiotoxicity and safety of genericsS Rijal
B P Koirala Institute of Health Sciences, Dharan, Nepal
Trans R Soc Trop Med Hyg 97:597-8. 2003
..These data show that every batch of generic SSG should be subject to rigorous quality control prior to use...
Lymphatic leishmaniasis--first case report from NepalS K Sharma
BP Koirala Institute of Health Sciences, Dharan, Nepal
Southeast Asian J Trop Med Public Health 32:749-50. 2001
..The bone marrow aspiration was negative for Leishmania donovani body. This is the first case of lymphatic leishmaniasis reported from Nepal...
Visceral leishmaniasis on the Indian sub-continent: a multi-centre study of the costs of three interventions for the control of the sandfly vector, Phlebotomus argentipesM Das
B P Koirala Institute of Health Sciences, Dharan 56701, Nepal
Ann Trop Med Parasitol 102:729-41. 2008
..Various combinations of these interventions (based on country-specific social and economic factors) may, however, be the best and most cost-effective choice...
Adenosine deaminase activity in sera of patients with visceral leishmaniasis in NepalN Baral
Department of Biochemistry, BP Koirala Institute of Health Sciences, Ghopa, BPKIHS, Dharan, Nepal
Trop Doct 35:86-8. 2005
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Orally effective drugs for kala-azar (visceral leishmaniasis): focus on miltefosine and sitamaquineH Sangraula
Department of Pharmacology, BP Koirala Institute of Health Sciences, Dharan, Nepal
J Assoc Physicians India 51:686-90. 2003
..It is expected that in future we would have effective ways to prevent and treat all forms of leishmaniasis without discomforting the patient...
Erythrocyte glutathione status in human visceral leishmaniasisD P Neupane
Department of Biochemistry, B P Koirala Institute of Health Sciences, Dharan, Nepal
Indian J Clin Biochem 23:95-7. 2008
..We concluded that visceral leishmaniasis patients are in oxidative stress which most likely induces the endogenous antioxidant such as GSH or its poor utilization by cells...
Neurocycticercosis--a reviewJ A Ansari
BP Koirala Institute of Health Sciences, Dharan, Nepal
Kathmandu Univ Med J (KUMJ) 1:48-55. 2003
Chronic cough in thymomaK K Agrawaal
Department of Internal Medicine, BPKIHS, Dharan, Nepal
JNMA J Nepal Med Assoc 49:164-6. 2010
..After all the common causes for chronic cough have been ruled out, unusual causes should also be considered in the differential diagnosis...
Diagnostic tests for kala-azar: a multi-centre study of the freeze-dried DAT, rK39 strip test and KAtex in East Africa and the Indian subcontinentM Boelaert
Epidemiology and Disease Control Unit, Institute of Tropical Medicine, Nationalestraat 155, 2000 Antwerp, Belgium
Trans R Soc Trop Med Hyg 102:32-40. 2008
..FD-DAT and rK39 can be recommended for clinical practice on the Indian subcontinent. In East Africa, their clinical use should be carefully monitored. More work is needed to improve existing formats, and to develop better VL diagnostics...
Gene expression profiling of Leishmania (Leishmania) donovani: overcoming technical variation and exploiting biological variationS Decuypere
Division of Infection and Immunity, Institute of Biomedical and Life Sciences, University of Glasgow, G12 8QQ, UK
Parasitology 135:183-94. 2008
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Prospective evaluation and comparison of the direct agglutination test and an rK39-antigen-based dipstick test for the diagnosis of suspected kala-azar in NepalF Chappuis
Department of Community Medicine, Geneva University Hospital, Geneva, Switzerland
Trop Med Int Health 8:277-85. 2003
..The rK39 dipstick is cheaper and easier to use than the DAT and could be used widely provided that both its performance and production remain stable...
Pott's spine and paraplegiaM P Gautam
Bir Hospital, NAMS, Kathmandu, Nepal
JNMA J Nepal Med Assoc 44:106-15. 2005
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