Prevalence of ECG abnormalities in an international survey of patients with suspected or confirmed heart failure at death or dischargeNasrin K Khan
University of Hull, Kingston upon Hull, United Kingdom
Eur J Heart Fail 9:491-501. 2007
..Most patients suspected of having heart failure (HF) will get a 12-lead electrocardiogram (ECG) but its utility for excluding HF or assisting in its management has rarely been investigated...
Epidemiology, associated factors, and prognostic outcomes of renal artery stenosis in chronic heart failure assessed by magnetic resonance angiographyRamesh de Silva
Academic Cardiology, University of Hull, Castle Hill Hospital, Cottingham, East Yorkshire, United Kingdom
Am J Cardiol 100:273-9. 2007
..Interventional trials on renal revascularization are underway that contain subsets of patients with HF that may provide evidence on how best to manage RAS in this setting...
High cocoa polyphenol rich chocolate may reduce the burden of the symptoms in chronic fatigue syndromeThozhukat Sathyapalan
Department of Endocrinology, Diabetes and Metabolism, Hull York Medical School, Michael White Diabetes Centre, Hull Royal Infirmary, 220 236 Anlaby Road, Hull, HU3 2RW UK
Nutr J 9:55. 2010
..The effect of polyphenol rich chocolate in subjects with chronic fatigue syndrome (CFS) has not been studied previously...
Statistical reviewing for disability and rehabilitationAlan S Rigby
Department of Academic Cardiology, Castle Hill Hospital, Castle Hill, Kingston upon Hull, UK
Disabil Rehabil 31:515-21. 2009
..The purpose of this article is to help authors in the review process, and to give the journal better statistical credentials...
Statistical methods in epidemiology. IX. Survival (failure-time) modelsAlan S Rigby
Academic Cardiology, University of Hull, and Hull York Medical School, Kingston upon Hull, UK
Disabil Rehabil 32:267-72. 2010
..This article introduces readers to survival (failure-time) models, with a focus on Kaplan-Meier curves, Cox regression and sample size estimation...
A survey of statistics in three UK general practice journalAlan S Rigby
Academic Cardiology, University of Hull, Kingston upon Hull, UK
BMC Med Res Methodol 4:28. 2004
..Given the main role of a general practitioner as a diagnostician we thought it would be of interest to see whether the statistical methods reported reflect the diagnostic process...
Statistical recommendations for papers submitted to Developmental Medicine & Child NeurologyAlan S Rigby
Academic Cardiology and Hull York Medical School, University of Hull, Kingston upon Hull, Hull, UK
Dev Med Child Neurol 52:299-304. 2010
..Because society depends on sound statistical practice, all practitioners of statistics, whatever their training or occupation, have social obligations to perform their work in a professional, competent, and ethical manner...
Statistical methods in epidemiology. VIII. On the use of likelihood ratios for diagnostic testing with an application to general practiceAlan S Rigby
Academic Department of Cardiology, University of Hull, Kingston upon Hull, UK
Disabil Rehabil 27:475-80. 2005
..These include odds ratios, reliability coefficients and the Chi-squared test. This paper continues the '2 x 2' theme but extends it to look at diagnostic testing. The setting is primary care, the disease is urological cancer...
Predictors of short term mortality in heart failure - insights from the Euro Heart Failure surveyPeriaswamy Velavan
Department of Academic Cardiology, University of Hull, UK
Int J Cardiol 138:63-9. 2010
..To identify factors associated with short term mortality in hospitalised patients with heart failure...
Renal artery stenosis: an innocent bystander or an independent predictor of worse outcome in patients with chronic heart failure? A magnetic resonance imaging studyChristos V Bourantas
Department of Cardiology, Academic Unit, University of Hull, Kingston upon Hull, UK
Eur J Heart Fail 14:764-72. 2012
..To investigate the prognostic impact of atherosclerotic renovascular disease in patients with chronic heart failure...
Relationship between plasma concentrations of N-terminal pro brain natriuretic peptide and the characteristics and outcome of patients with a clinical diagnosis of diastolic heart failure: a report from the PEP-CHF studyJohn G F Cleland
Department of Cardiology, Castle Hill Hospital, University of Hull, Kingston upon Hull, UK
Eur J Heart Fail 14:487-94. 2012
..The lack of a simple, objective test to identify patients with HFPEF at increased risk of cardiovascular events would be valuable...
Mortality at low and high estimated glomerular filtration rate values: a 'U' shaped curveHeidi J Cox
Department of Clinical Biochemistry, Hull Royal Infirmary, Hull, UK
Nephron Clin Pract 110:c67-72. 2008
..While a low estimated glomerular filtration rate (eGFR) confers an increased risk of dying, the mortality associated with high eGFR values has not been ascertained...
Relationship between right ventricular volumes measured by cardiac magnetic resonance imaging and prognosis in patients with chronic heart failureChristos V Bourantas
Department of Cardiology, Academic Unit, University of Hull, Kingston upon Hull, PO Box HU16 5JQ, UK
Eur J Heart Fail 13:52-60. 2011
..The aim of this study was to investigate the prognostic impact of right ventricular (RV) size in patients with chronic heart failure...
Atherosclerotic disease of the abdominal aorta and its branches: prognostic implications in patients with heart failureChristos V Bourantas
Department of Cardiology, Academic Unit, University of Hull, PO Box HU16 5JQ, Kingston upon Hull, UK
Heart Fail Rev 17:229-39. 2012
..How such disease should be managed remains uncertain, but its recognition and characterisation are the first steps in finding out...
The timing of development and subsequent clinical course of heart failure after a myocardial infarctionAzam Torabi
Department of Cardiology, Hull Royal Infirmary, University of Hull Castle Hill Hospital, Kingston upon Hull, Castle Road, Cottingham, East Yorkshire HU16 5JQ, UK
Eur Heart J 29:859-70. 2008
..The cumulative incidence, persistence, and resolution of HF after MI are poorly described. The aim of this study is to describe the natural history and prognosis of HF after an MI...
Relationship of high-sensitivity C-reactive protein to prognosis and other prognostic markers in outpatients with heart failureJonathan D Windram
Academic Cardiology Department, University of Hull, Hull Royal Infirmary Castle Hill Hospital, Hull, United Kingdom
Am Heart J 153:1048-55. 2007
..We aimed to investigate the relationship between hsCRP and prognosis in patients with CHF and left ventricular systolic dysfunction (LVSD)...
Effect of glucose variability on the long-term risk of microvascular complications in type 1 diabetesEric S Kilpatrick
Department of Clinical Biochemistry, Hull Royal Infirmary, Hull, UK
Diabetes Care 32:1901-3. 2009
....
Cardiac output does not limit submaximal exercise capacity in patients with chronic heart failureRhidian J Shelton
Department of Academic Cardiology, Castle Hill Hospital, University of Hull, Kingston upon Hull, UK
Eur J Heart Fail 12:983-9. 2010
..We aimed to determine the effect of submaximal exercise on CO and other haemodynamic variables in patients with CHF using a validated non-invasive inert gas rebreathing system...
The Diabetes Control and Complications Trial: the gift that keeps givingEric S Kilpatrick
Department of Clinical Biochemistry, Hull Royal Infirmary and Hull York Medical School, Hull, UK
Nat Rev Endocrinol 5:537-45. 2009
..In conclusion, the DCCT continues to provide new insights into type 1 diabetes mellitus, which are of benefit to patients over a quarter of a century after the trial was started...
Lack of diastolic reserve in patients with heart failure and normal ejection fractionSudipta Chattopadhyay
Department of Cardiology, University of Hull, Kingston upon Hull, United Kingdom
Circ Heart Fail 3:35-43. 2010
..CONCLUSIONS: Impaired diastolic reserve results in stress-induced increase in the left ventricular end-diastolic pressure in patients with HFNEF giving rise to exercise intolerance...
Relationship of high sensitivity C reactive peptide (hsCRP) to prognosis and other prognostic markers in outpatients with heart failureJonathan David Windram
Department of Academic Cardiology, University of Hull, HU3 2JZ Hull, United Kingdom
Am Heart J 155:e9. 2008
The effects of initiation or continuation of statin therapy on cholesterol level and all-cause mortality after the diagnosis of left ventricular systolic dysfunctionPoay Huan Loh
Academic Cardiology Department, University of Hull, Hull Royal Infirmary, Hull, UK
Am Heart J 153:537-44. 2007
..This study investigated the effect of changes in statin therapy and cholesterol level on mortality in patients with LVSD...
The role of blood pressure variability in the development of nephropathy in type 1 diabetesEric S Kilpatrick
Department of Clinical Biochemistry, Hull Royal Infirmary, Hull, UK
Diabetes Care 33:2442-7. 2010
..This study has investigated whether each may also influence the development of microvascular complications in type 1 diabetes by examining data from the Diabetes Control and Complications Trial (DCCT)...
Noninvasive home telemonitoring for patients with heart failure at high risk of recurrent admission and death: the Trans-European Network-Home-Care Management System (TEN-HMS) studyJohn G F Cleland
Department of Cardiology, University of Hull, Kingston upon Hull, United Kingdom
J Am Coll Cardiol 45:1654-64. 2005
..We sought to identify whether home telemonitoring (HTM) improves outcomes compared with nurse telephone support (NTS) and usual care (UC) for patients with heart failure who are at high risk of hospitalization or death...
The national heart failure audit for England and Wales 2008-2009John G F Cleland
Department of Cardiology, Castle Hill Hospital, Hull York Medical School, University of Hull, Cottingham, Kingston upon Hull, UK
Heart 97:876-86. 2011
..To obtain national data on the clinical characteristics, investigation, management and outcome of patients hospitalised with a diagnosis of heart failure...
Clinical trials update from the American Heart Association 2007: CORONA, RethinQ, MASCOT, AF-CHF, HART, MASTER, POISE and stem cell therapyJohn G F Cleland
Department of Cardiology, University of Hull, Castle Hill Hospital, Cottingham, Kingston upon Hull, HU16 5JQ, UK
Eur J Heart Fail 10:102-8. 2008
..Three trials of stem cell therapy in post-MI patients gave conflicting results...
The diagnostic utility of N-terminal pro-B-type natriuretic peptide for the detection of major structural heart disease in patients with atrial fibrillationRhidian J Shelton
Department of Cardiology, Castle Hill Hospital, Cottingham, Kingston upon Hull HU16 5JQ, UK
Eur Heart J 27:2353-61. 2006
..NT-proBNP is elevated in MSHD and heart failure (HF). AF, a common finding in HF and MSHD, is also associated with raised plasma NT-proBNP. As a result, the utility of NT-proBNP for predicting MSHD may be reduced...
Clinical trials update from the American Heart Association meeting: ACORN-CSD, primary care trial of chronic disease management, PEACE, CREATE, SHIELD, A-HeFT, GEMINI, vitamin E meta-analysis, ESCAPE, CARP, and SCD-HeFT cost-effectiveness studyRhidian J Shelton
Department of Cardiology, University of Hull, Castle Hill Hospital, Cottingham, Kingston-upon-Hull, HU15 5JQ, UK
Eur J Heart Fail 7:127-35. 2005
..Analysis of data from SCD-HeFT supports the cost-effectiveness of ICDs in heart failure, although overall cost implications may be prohibitive...
Predicting thyroxine requirements following total thyroidectomyDipan Mistry
ENT Department, Castle Hill Hospital, Cottingham, Hull, UK
Clin Endocrinol (Oxf) 74:384-7. 2011
..The aim of this study was to determine the best formula to determine the initiated replacement dose of levothyroxine immediately following total thyroidectomy...
The effect of parathyroidectomy on neuropsychological symptoms and biochemical parameters in patients with asymptomatic primary hyperparathyroidismHassan Kahal
Academic Endocrinology, Diabetes and Metabolism, Hull York Medical School, Hull, UK
Clin Endocrinol (Oxf) 76:196-200. 2012
..With increased biochemical screening, primary hyperparathyroidism (pHPT) is often discovered incidentally whilst patients are asymptomatic...
A1C variability and the risk of microvascular complications in type 1 diabetes: data from the Diabetes Control and Complications TrialEric S Kilpatrick
Department of Clinical Biochemistry, Hull Royal Infirmary, Hull, UK
Diabetes Care 31:2198-202. 2008
..In this study, we analyzed data from the Diabetes Control and Complications Trial (DCCT) to assess the effect of A1C variability on the risk of retinopathy and nephropathy in patients with type 1 diabetes...
Anemia, renal dysfunction, and their interaction in patients with chronic heart failureRamesh de Silva
Academic Cardiology, University of Hull, Castle Hill Hospital, Cottingham, United Kingdom
Am J Cardiol 98:391-8. 2006
..In conclusion, in outpatients with chronic HF, anemia and RD are common and co-exist but confer independent prognostic information. A deficiency of conventional hematinic factors may cause about 1/3 of anemia in this clinical setting...
Incidence of renal dysfunction over 6 months in patients with chronic heart failure due to left ventricular systolic dysfunction: contributing factors and relationship to prognosisRamesh de Silva
Academic Department of Cardiology, Castle Hill Hospital, University of Hull, Castle Road, Cottingham, Hull HU16 5JQ, UK
Eur Heart J 27:569-81. 2006
....
The reproducibility and sensitivity of the 6-min walk test in elderly patients with chronic heart failureLee Ingle
Department of Academic Cardiology, Castle Hill Hospital, Castle Road, Cottingham, Hull HU16 5JQ, UK
Eur Heart J 26:1742-51. 2005
....
Patients with new onset haematuria: assessing the discriminant value of clinical information in relation to urological malignanciesNicholas Summerton
Department of Primary Care, University of Hull
Br J Gen Pract 52:284-9. 2002
..There is little information available to assist general practitioners (GPs) in deciding which patients with haematuria are likely to have a malignancy...
Disability in young adults following major trauma: 5 year follow up of survivorsSian A Evans
Nuffield Institute for Health, University of Leeds
BMC Public Health 3:8. 2003
..Injuries are a major cause of mortality and morbidity in young people. Despite this, the long-term consequences for young survivors of severe injury are relatively unexplored...
The general practitioner-patient consultation pattern as a tool for cancer diagnosis in general practiceNicholas Summerton
Department of Public Health and Primary Care, University of Hull
Br J Gen Pract 53:50-2. 2003
..03), as well as after the exclusion of patients identified by routine screening (P = 0.05)...
Variability in the relationship between mean plasma glucose and HbA1c: implications for the assessment of glycemic controlEric S Kilpatrick
Department of Clinical Biochemistry, Hull Royal Infirmary, Hull, United Kingdom
Clin Chem 53:897-901. 2007
..We examined the relationship in different treatment groups of patients with type 1 diabetes participating in the Diabetes Control and Complications Trial (DCCT)...
Prognostic value of the 6 min walk test and self-perceived symptom severity in older patients with chronic heart failureLee Ingle
Carnegie Research Institute, Leeds Metropolitan University, Beckett s Park Campus, Leeds LS6 3QS, UK
Eur Heart J 28:560-8. 2007
..However, the prognostic value of the 6-MWT in a large, representative sample of CHF patients, and in patients with different degrees of left ventricular systolic dysfunction (LVSD) remains unclear...
Seizure frequency in adults with Wolf-Hirschhorn syndromeJeanie C Worthington
Department of Clinical Genetics, Sheffield Children s Hospital, Sheffield, UK
Am J Med Genet A 146:2528-31. 2008
..This reached statistical significance: chi(2) = 4.6, P = 0.03, odds ratio = 6.5 (95% CI 1.1-38.6). Data from this survey may be helpful when counseling families with a very young child with WHS...