Edo Richard

Summary

Publications

  1. ncbi Prevention of dementia by intensive vascular care (PreDIVA): a cluster-randomized trial in progress
    Edo Richard
    Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Alzheimer Dis Assoc Disord 23:198-204. 2009
  2. ncbi Vascular care in patients with Alzheimer's disease with cerebrovascular lesions-a randomized clinical trial
    Edo Richard
    Academic Medical Centre, University of Amsterdam, Postbus 22660, Amsterdam 1100DD, The Netherlands
    J Am Geriatr Soc 57:797-805. 2009
  3. doi Association of vascular factors with apathy in community-dwelling elderly individuals
    Suzanne A Ligthart
    Department of General Practice, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Arch Gen Psychiatry 69:636-42. 2012
  4. pmc Treatment of cardiovascular risk factors to prevent cognitive decline and dementia: a systematic review
    Suzanne A Ligthart
    Department of General Practice, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Vasc Health Risk Manag 6:775-85. 2010
  5. doi Vascular risk factors as treatment target to prevent cognitive decline
    Edo Richard
    Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Alzheimers Dis 32:733-40. 2012
  6. doi Cardiovascular risk management in community-dwelling elderly: opportunities for prevention
    Suzanne A Ligthart
    University of Amsterdam, Amsterdam, The Netherlands
    Eur J Prev Cardiol 19:1365-72. 2012
  7. ncbi Apathy is an independent risk factor for incident cardiovascular disease in the older individual: a population-based cohort study
    Lisa S M Eurelings
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Int J Geriatr Psychiatry 29:454-63. 2014
  8. pmc Late-life depression, mild cognitive impairment, and dementia
    Edo Richard
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    JAMA Neurol 70:374-82. 2013
  9. ncbi The Alzheimer myth and biomarker research in dementia
    Edo Richard
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Alzheimers Dis 31:S203-9. 2012
  10. doi Aspirin in Alzheimer's disease: increased risk of intracerebral hemorrhage: cause for concern?
    Hanneke Thoonsen
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Stroke 41:2690-2. 2010

Detail Information

Publications16

  1. ncbi Prevention of dementia by intensive vascular care (PreDIVA): a cluster-randomized trial in progress
    Edo Richard
    Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Alzheimer Dis Assoc Disord 23:198-204. 2009
    ..Here, we report the outline of a pragmatic study that will attempt to answer this question and we describe the prevalence of cardiovascular risk factors in the target population...
  2. ncbi Vascular care in patients with Alzheimer's disease with cerebrovascular lesions-a randomized clinical trial
    Edo Richard
    Academic Medical Centre, University of Amsterdam, Postbus 22660, Amsterdam 1100DD, The Netherlands
    J Am Geriatr Soc 57:797-805. 2009
    ..To investigate whether vascular care slows dementia progression in patients with Alzheimer's disease with cerebrovascular lesions on neuroimaging...
  3. doi Association of vascular factors with apathy in community-dwelling elderly individuals
    Suzanne A Ligthart
    Department of General Practice, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Arch Gen Psychiatry 69:636-42. 2012
    ..Apathy in community-dwelling elderly individuals has been associated with a history of stroke and other cardiovascular disease...
  4. pmc Treatment of cardiovascular risk factors to prevent cognitive decline and dementia: a systematic review
    Suzanne A Ligthart
    Department of General Practice, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Vasc Health Risk Manag 6:775-85. 2010
    ..So far, few randomized controlled trials have focused on lowering the vascular risk profile to prevent or postpone cognitive decline or dementia...
  5. doi Vascular risk factors as treatment target to prevent cognitive decline
    Edo Richard
    Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Alzheimers Dis 32:733-40. 2012
    ..In this review we discuss several pertinent methodological issues that need to be addressed to achieve an optimal design of new randomized controlled trials...
  6. doi Cardiovascular risk management in community-dwelling elderly: opportunities for prevention
    Suzanne A Ligthart
    University of Amsterdam, Amsterdam, The Netherlands
    Eur J Prev Cardiol 19:1365-72. 2012
    ....
  7. ncbi Apathy is an independent risk factor for incident cardiovascular disease in the older individual: a population-based cohort study
    Lisa S M Eurelings
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Int J Geriatr Psychiatry 29:454-63. 2014
    ..In this study, we prospectively assess whether symptoms of apathy and depression are independent risk factors for incident CVD and stroke...
  8. pmc Late-life depression, mild cognitive impairment, and dementia
    Edo Richard
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    JAMA Neurol 70:374-82. 2013
    ..To evaluate the association of late-life depression with mild cognitive impairment (MCI) and dementia in a multiethnic community cohort...
  9. ncbi The Alzheimer myth and biomarker research in dementia
    Edo Richard
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Alzheimers Dis 31:S203-9. 2012
    ..Acknowledging that dementia in old age is an essentially different condition from dementia at relatively younger age is needed and should lead to new approaches in dementia research...
  10. doi Aspirin in Alzheimer's disease: increased risk of intracerebral hemorrhage: cause for concern?
    Hanneke Thoonsen
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Stroke 41:2690-2. 2010
    ..Here, we evaluate the literature on the risk of ICH as a complication in patients with AD treated with aspirin...
  11. doi Characteristics of dyshoric capillary cerebral amyloid angiopathy
    Edo Richard
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Neuropathol Exp Neurol 69:1158-67. 2010
    ..These results suggest that capCAA is pathologically and possibly pathogenetically distinct from larger vessel CAA, and that it is associated with a high APOE-ε4 allele frequency...
  12. ncbi Responsiveness of magnetic resonance imaging and neuropsychological assessment in memory clinic patients
    Ben Schmand
    Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands Department of Psychology, University of Amsterdam, Amsterdam, The Netherlands
    J Alzheimers Dis 40:409-18. 2014
    ..e., relatively insensitive to change). Large patient samples are needed to detect beneficial drug effects. Therefore, magnetic resonance imaging (MRI) measures of cerebral atrophy have been proposed as surrogate endpoints...
  13. doi Methodological challenges in designing dementia prevention trials - the European Dementia Prevention Initiative (EDPI)
    Edo Richard
    Dept of Neurology, Academic Medical Centre, University of Amsterdam, The Netherlands
    J Neurol Sci 322:64-70. 2012
    ..Founding of EDPI is an important first step in this direction...
  14. doi Morphometric changes in the cortical microvascular network in Alzheimer's disease
    Edo Richard
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Alzheimers Dis 22:811-8. 2010
    ..Our data indicate that morphometric changes in the cortical capillary network occur in AD in a region-specific manner and may be related to cortical atrophy in the affected regions...
  15. ncbi Vascular Care in Patients With Alzheimer Disease With Cerebrovascular Lesions Slows Progression of White Matter Lesions on MRI: The Evaluation of Vascular Care in Alzheimer's Disease (EVA) Study
    Edo Richard
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, Postbus 22660, 1100 DD, The Netherlands
    Stroke 41:554-6. 2010
    ..Treatment aimed at vascular risk factors in patients with early Alzheimer disease may be beneficial, possibly in an even earlier stage of the disease...
  16. ncbi Cholinesterase inhibitors in dementia: yes, no, or maybe?
    Afina W Lemstra
    Academic Medical Centre, Department of Neurology, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Age Ageing 36:625-7. 2007