Thiopurine methyltransferase (TPMT) genotype distribution in azathioprine-tolerant and -intolerant patients with various disorders. The impact of TPMT genotyping in predicting toxicityLene O Reuther
Department of Clinical Pharmacology, Gentofte University Hospital, 2900 Hellerup, Denmark
Eur J Clin Pharmacol 59:797-801. 2004
..To study the distribution of the thiopurine methyltransferase (TPMT) genotype among azathioprine (Aza)-tolerant and -intolerant patients with various disorders, and to investigate a possible relationship with the Aza metabolite levels...
[Changing clinicians' prescription patterns]Lene Ørskov Reuther
Klinisk Farmakologisk Enhed, Bispebjerg Hospital, DK 2400 København NV
Ugeskr Laeger 171:2655-6. 2009
..With a little effort, the Central Drug Committee succeeded in changing clinicians' prescription pattern in a cost-effective manner...
[Application of the medicine profile in an ambulatory setting]Lene Ørskov Reuther
Bispebjerg Hospital, Klinisk Farmakologisk Enhed, København NV
Ugeskr Laeger 170:2427-32. 2008
..The PEM provides an overview and contains an overview of the prescription medicine sold to the patient over the previous two years...
Pharmacological monitoring of azathioprine therapyL O Reuther
Dept of Clinical Pharmacology, Gentofte University Hospital, Hellerup, Denmark
Scand J Gastroenterol 38:972-7. 2003
..In a cross-sectional study we investigated relationships between the clinical outcome and Aza dose, the TPMT genotype and the Aza metabolite levels among patients with Crohn disease...
Multi-dose drug dispensing is a challenge across the primary-secondary care interfaceLene Orskov Reuther
Department of Clinical Pharmacology, Bispebjerg Hospital, 2400 Copenhagen NV, Denmark
Dan Med Bull 58:A4341. 2011
..The purpose of the present study was to investigate how a hospital MDDD instruction was followed...
Thiopurine methyltransferase genotype distribution in patients with Crohn's diseaseL O Reuther
Department of Clinical Pharmacology, Gentofte University Hospital, DK 2900 Hellerup, Denmark
Aliment Pharmacol Ther 17:65-8. 2003
..TPMT genotyping in adult patients with Crohn's disease has never been performed systematically...
[Treatment of trichomonas vaginitis in pregnant women]Lene Ørskov Reuther
Klinisk Farmakologisk Enhed, H S Bispebjerg Hospital, DK 2400 København
Ugeskr Laeger 164:2489. 2002
[Medication errors after hospitalisation due to multi-dose drug dispensing in the primary sector]Charlotte Lysén
Klinisk Farmakologisk Afdeling, Bispebjerg Hospital, 2400 København NV, Denmark
Ugeskr Laeger 173:1944-5. 2011
..These problems has until now been underestimated...
[Drug committees towards the regions. The Danish Society of Clinical Pharmacology]Lene Ørskov Reuther
Klinisk Farmakologisk Enhed, Bispebjerg Hospital, DK 2400 København NV
Ugeskr Laeger 169:1113. 2007
Effect of growth hormone on hepatic cytochrome P450 activity in healthy elderly menGesche Jürgens
Department of Clinical Pharmacology, Bispebjerg University Hospital, Copenhagen, Denmark
Clin Pharmacol Ther 71:162-8. 2002
..Our objective was to study the effect of recombinant human growth hormone (rhGH) on hepatic cytochrome P450 (CYP) activity in 30 healthy elderly men...
Is a targeted intensive intervention effective for improvements in hypertension control? A randomized controlled trialLene Ørskov Reuther
Department of Clinical Pharmacology, Bispebjerg Hospital, København NV, Denmark
Fam Pract 29:626-32. 2012
..However, achieving a regulated BP in hypertensive patients is still a challenge...
[Drug-induced seizures]Lene Ørskov Reuther
H S Bispebjerg Hospital, Klinisk Farmakologisk Enhed, og Laegemiddelstyrelsen, Institut for Rationel Farmakoterapi
Ugeskr Laeger 165:1447-51. 2003
..In case of suspicion of drug-induced seizures, reporting should be made to the Danish Medicines Agency. If the drug has been on the market less than two years, reporting is mandatory...
[Combination therapy with acetylsalicylic acid and non-aspirin nonsteroidal anti-inflammatory drugs]Lene Ørskov Reuther
H S Bispebjerg Hospital, Klinisk Farmakologisk Enhed, København NV
Ugeskr Laeger 168:1310-4. 2006
..This review attempts to answer these questions...