Mingqiang Ren

Summary

Publications

  1. pmc Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease
    Mingqiang Ren
    Georgia Health Sciences University Cancer Center, Augusta, GA, USA
    Blood 117:6837-47. 2011
  2. pmc Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities
    M Ren
    Georgia Health Sciences University, Cancer Center, Augusta, GA 30912, USA
    Leukemia 27:32-40. 2013
  3. pmc Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases
    Mingqiang Ren
    Georgia Health Sciences University School of Medicine, Augusta, Georgia, USA
    Cancer Res 71:7312-22. 2011
  4. pmc Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models
    Mingqiang Ren
    Georgia Regents University Cancer Center, 1120 15th St, Augusta, GA 30912, USA
    Blood 122:1007-16. 2013
  5. doi Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1
    Mingqiang Ren
    Cancer Center, Department of Medicine, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA
    Oncol Rep 29:2181-90. 2013
  6. pmc HOXC9 directly regulates distinct sets of genes to coordinate diverse cellular processes during neuronal differentiation
    Xiangwei Wang
    Cancer Center, Georgia Regents University, Augusta, GA 30912, USA
    BMC Genomics 14:830. 2013
  7. pmc Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage
    Mingqiang Ren
    Georgia Health Sciences University Cancer Center, Georgia Health Sciences University School of Medicine, Augusta, Georgia, United States of America
    PLoS ONE 7:e38265. 2012
  8. pmc Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase
    Mingqiang Ren
    Medical College of Georgia Cancer Center, Augusta, GA 30912, USA
    Blood 114:1576-84. 2009
  9. pmc NF-κB2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors
    Brian A McCarthy
    Cancer Center and Department of Pathology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA
    BMC Cancer 12:203. 2012

Collaborators

Detail Information

Publications9

  1. pmc Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease
    Mingqiang Ren
    Georgia Health Sciences University Cancer Center, Augusta, GA, USA
    Blood 117:6837-47. 2011
    ..These data demonstrate the importance of Notch signaling in the etiology of SCLL, and suggest that targeting this pathway could provide a novel strategy for molecular therapies to treat SCLL patients...
  2. pmc Ponatinib suppresses the development of myeloid and lymphoid malignancies associated with FGFR1 abnormalities
    M Ren
    Georgia Health Sciences University, Cancer Center, Augusta, GA 30912, USA
    Leukemia 27:32-40. 2013
    ....
  3. pmc Src activation plays an important key role in lymphomagenesis induced by FGFR1 fusion kinases
    Mingqiang Ren
    Georgia Health Sciences University School of Medicine, Augusta, Georgia, USA
    Cancer Res 71:7312-22. 2011
    ....
  4. pmc Dysregulated signaling pathways in the development of CNTRL-FGFR1-induced myeloid and lymphoid malignancies associated with FGFR1 in human and mouse models
    Mingqiang Ren
    Georgia Regents University Cancer Center, 1120 15th St, Augusta, GA 30912, USA
    Blood 122:1007-16. 2013
    ..These data indicate that simultaneously targeting these pathways is essential to successfully treating this almost invariably lethal disease...
  5. doi Novel FGFR inhibitor ponatinib suppresses the growth of non-small cell lung cancer cells overexpressing FGFR1
    Mingqiang Ren
    Cancer Center, Department of Medicine, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA
    Oncol Rep 29:2181-90. 2013
    ..Our data indicate that pharmacological inhibition of FGFR1 kinase activity with ponatinib may be effective for the treatment of lung cancer patients whose tumors overexpress FGFR1...
  6. pmc HOXC9 directly regulates distinct sets of genes to coordinate diverse cellular processes during neuronal differentiation
    Xiangwei Wang
    Cancer Center, Georgia Regents University, Augusta, GA 30912, USA
    BMC Genomics 14:830. 2013
    ..It is largely unknown how these diverse cellular events are coordinated at the molecular level during differentiation. We addressed this question in a model system of neuroblastoma cell differentiation induced by HOXC9...
  7. pmc Acute progression of BCR-FGFR1 induced murine B-lympho/myeloproliferative disorder suggests involvement of lineages at the pro-B cell stage
    Mingqiang Ren
    Georgia Health Sciences University Cancer Center, Georgia Health Sciences University School of Medicine, Augusta, Georgia, United States of America
    PLoS ONE 7:e38265. 2012
    ....
  8. pmc Genetic fingerprinting of the development and progression of T-cell lymphoma in a murine model of atypical myeloproliferative disorder initiated by the ZNF198-fibroblast growth factor receptor-1 chimeric tyrosine kinase
    Mingqiang Ren
    Medical College of Georgia Cancer Center, Augusta, GA 30912, USA
    Blood 114:1576-84. 2009
    ..Thus, we have defined an important event in the process of ZNF198-FGFR1-induced T-cell leukemia...
  9. pmc NF-κB2 mutation targets survival, proliferation and differentiation pathways in the pathogenesis of plasma cell tumors
    Brian A McCarthy
    Cancer Center and Department of Pathology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA 30912, USA
    BMC Cancer 12:203. 2012
    ..We investigated these questions by using a transgenic mouse model with lymphocyte-targeted expression of p80HT, a lymphoma-associated NF-κB2 mutant, and human multiple myeloma cell lines...