Jianan Ren

Summary

Publications

  1. ncbi request reprint Efficacy of T2 in active Crohn's disease: a prospective study report
    Jianan Ren
    Department of General Surgery, Jinling Hospital, Nanjing, 210002, PR China
    Dig Dis Sci 52:1790-7. 2007
  2. doi request reprint Persistent inflammation-immunosuppression catabolism syndrome, a common manifestation of patients with enterocutaneous fistula in intensive care unit
    Dong Hu
    From the Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    J Trauma Acute Care Surg 76:725-9. 2014
  3. doi request reprint Preliminary case-control study to evaluate diagnostic values of C-reactive protein and erythrocyte sedimentation rate in differentiating active Crohn's disease from intestinal lymphoma, intestinal tuberculosis and Behcet's syndrome
    Song Liu
    Medical School of Nanjing University, Departments of General Surgery SL, Jr, XW, HR, DY, GW, GG, JL and Pathology QX, Jinling Hospital, Nanjing, China Department of General Surgery GH, Second Affiliated Hospital of Jilin University, General Surgery Center of Jilin University, Jilin, China and Center for the Study of Inflammatory Bowel Disease SL, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts
    Am J Med Sci 346:467-72. 2013
  4. doi request reprint Efficacy of erythropoietin combined with enteral nutrition for the treatment of anemia in Crohn's disease: a prospective cohort study
    Song Liu
    Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Nutr Clin Pract 28:120-7. 2013
  5. ncbi request reprint Autologous platelet rich fibrin glue for sealing of low-output enterocutaneous fistulas: an observational cohort study
    Xiuwen Wu
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, P R China
    Surgery 155:434-41. 2014
  6. doi request reprint Prevention of postoperative recurrence of Crohn's disease: Tripterygium wilfordii polyglycoside versus mesalazine
    Jianan Ren
    Department of Surgery, Jinling Hospital, Nanjing University Medical School, Nanjing, China
    J Int Med Res 41:176-87. 2013
  7. doi request reprint Nonthyroidal illness syndrome: is it far away from Crohn's disease?
    Song Liu
    Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    J Clin Gastroenterol 47:153-9. 2013
  8. ncbi request reprint Open abdomen treatment for septic patients with gastrointestinal fistula: from fistula control to definitive closure
    Jianan Ren
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Am Surg 80:339-47. 2014
  9. ncbi request reprint Fluid volume overload negatively influences delayed primary facial closure in open abdomen management
    Qian Huang
    Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, People s Republic of China Electronic address
    J Surg Res 187:122-7. 2014
  10. doi request reprint Crohn's disease and polymorphism of heat shock protein gene HSP70-2 in the Chinese population
    Jun Chen
    The Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu Province, China
    J Gastroenterol Hepatol 28:814-8. 2013

Collaborators

Detail Information

Publications33

  1. ncbi request reprint Efficacy of T2 in active Crohn's disease: a prospective study report
    Jianan Ren
    Department of General Surgery, Jinling Hospital, Nanjing, 210002, PR China
    Dig Dis Sci 52:1790-7. 2007
    ..Endoscopic improvements were observed at week 12. In conclusion, T2 appears to be effective for the treatment of mildly or moderately active CD. Further controlled studies are warranted for this promising drug...
  2. doi request reprint Persistent inflammation-immunosuppression catabolism syndrome, a common manifestation of patients with enterocutaneous fistula in intensive care unit
    Dong Hu
    From the Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    J Trauma Acute Care Surg 76:725-9. 2014
    ..Enterocutaneous fistula (ECF) is one of the most challenging complications in the practice of surgery. However, no studies have been performed connecting PICS with ECF...
  3. doi request reprint Preliminary case-control study to evaluate diagnostic values of C-reactive protein and erythrocyte sedimentation rate in differentiating active Crohn's disease from intestinal lymphoma, intestinal tuberculosis and Behcet's syndrome
    Song Liu
    Medical School of Nanjing University, Departments of General Surgery SL, Jr, XW, HR, DY, GW, GG, JL and Pathology QX, Jinling Hospital, Nanjing, China Department of General Surgery GH, Second Affiliated Hospital of Jilin University, General Surgery Center of Jilin University, Jilin, China and Center for the Study of Inflammatory Bowel Disease SL, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts
    Am J Med Sci 346:467-72. 2013
    ..This study is designed to investigate potential differential capacity of the 3 biomarkers between these disorders...
  4. doi request reprint Efficacy of erythropoietin combined with enteral nutrition for the treatment of anemia in Crohn's disease: a prospective cohort study
    Song Liu
    Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Nutr Clin Pract 28:120-7. 2013
    ....
  5. ncbi request reprint Autologous platelet rich fibrin glue for sealing of low-output enterocutaneous fistulas: an observational cohort study
    Xiuwen Wu
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, P R China
    Surgery 155:434-41. 2014
    ..This study aimed to determine efficacy and safety of autologous, platelet-rich fibrin glue (PRFG) in promoting closure of ECFs...
  6. doi request reprint Prevention of postoperative recurrence of Crohn's disease: Tripterygium wilfordii polyglycoside versus mesalazine
    Jianan Ren
    Department of Surgery, Jinling Hospital, Nanjing University Medical School, Nanjing, China
    J Int Med Res 41:176-87. 2013
    ..To explore effectiveness and safety of polyglycosides of Tripterygium wilfordii (GTW) and mesalazine (5-aminosalicylic acid [5-ASA]) in preventing postoperative clinical and endoscopic recurrence of Crohn's disease...
  7. doi request reprint Nonthyroidal illness syndrome: is it far away from Crohn's disease?
    Song Liu
    Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    J Clin Gastroenterol 47:153-9. 2013
    ....
  8. ncbi request reprint Open abdomen treatment for septic patients with gastrointestinal fistula: from fistula control to definitive closure
    Jianan Ren
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Am Surg 80:339-47. 2014
    ..A delayed and deliberate operative strategy aiming at fistula excision and fascial closure, with simultaneous abdominal wall reconstruction, was required for the infected open abdomen. ..
  9. ncbi request reprint Fluid volume overload negatively influences delayed primary facial closure in open abdomen management
    Qian Huang
    Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, People s Republic of China Electronic address
    J Surg Res 187:122-7. 2014
    ..Factors influencing primary fascial closure, however, are unknown. This study aims to explore the influence of fluid volume overload on the application of vacuum-assisted and mesh-mediated fascial traction (VAWCM) in OA treatment...
  10. doi request reprint Crohn's disease and polymorphism of heat shock protein gene HSP70-2 in the Chinese population
    Jun Chen
    The Research Institute of General Surgery, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, Jiangsu Province, China
    J Gastroenterol Hepatol 28:814-8. 2013
    ..The purpose of this study was to identify associations between the HSP70-2 polymorphism and the clinical courses of CD in the Chinese population...
  11. doi request reprint Nonthyroidal illness syndrome in enterocutaneous fistulas
    Gang Han
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, China
    Am J Surg 206:386-92. 2013
    ..The aim of this study was to investigate the incidence, etiology, clinical outcomes, and prognosis of nonthyroidal illness syndrome (NTIS) in patients with enterocutaneous fistulas...
  12. ncbi request reprint Recombinant human thrombopoietin improves platelet counts and reduces platelet transfusion possibility among patients with severe sepsis and thrombocytopenia: A prospective study
    Qin Wu
    Department of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    J Crit Care 29:362-6. 2014
    ..The present study was dedicated to evaluate the efficiency of rhTPO in improving PCs in patients with severe sepsis...
  13. doi request reprint T2 enhances in situ level of Foxp3+ regulatory cells and modulates inflammatory cytokines in Crohn's disease
    Guanwei Li
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, PR China Electronic address
    Int Immunopharmacol 18:244-8. 2014
    ..T2, extracted from the medicinal plant Tripterygium wilfordii Hook F, has already been proved to be therapeutically effective in inducing the remission of CD. However, the mechanisms in human studies remain largely unknown...
  14. doi request reprint The effect of human complement C3 protein applied at different times in treatment of polymicrobial sepsis
    Yujie Yuan
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, People s Republic of China
    Inflamm Res 61:581-9. 2012
    ..This study was designed to investigate the effect of exogenous complement C3 administration on outcomes of sepsis and identify an optimal time for this therapy...
  15. doi request reprint "Fistula patch": making the treatment of enteroatmospheric fistulae in the open abdomen easier
    Gefei Wang
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    J Trauma Acute Care Surg 74:1175-7. 2013
    ..However, the loss of enteric fistula effluent would potentially lead to a risk of the disturbance of internal environment and malnutrition...
  16. pmc Dynamics of albumin synthetic response to intra-abdominal abscess in patients with gastrointestinal fistula
    Bo Zhou
    1 Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, People s Republic of China
    Surg Infect (Larchmt) 15:111-7. 2014
    ..We investigated in a group of patients with gastrointestinal fistula the dynamic response of liver albumin synthesis to intra-abdominal abscess and how these related to hypoalbuminemia and circulating endocrine hormone profiles...
  17. ncbi request reprint Biocompatibility, biodegradation, and neovascularization of human single-unit platelet-rich fibrin glue: an in vivo analysis
    Xiuwen Wu
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, Jiangsu 210002, China
    Chin Med J (Engl) 127:408-11. 2014
    ..The aim of this study was to evaluate the biocompatibility and biodegradation of different formulations of platelet-rich fibrin glue in vivo and examine its effects on the neovascularization of wound sites...
  18. doi request reprint Early enteral nutrition improves outcomes of open abdomen in gastrointestinal fistula patients complicated with severe sepsis
    Yujie Yuan
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, PR China
    Nutr Clin Pract 26:688-94. 2011
    ..The purpose of this study is to evaluate the role of early nutrition therapy in that population...
  19. doi request reprint Fistula fiberscope-assisted percutaneous glue sealing for enterocutaneous fistulas: a case report
    Jianan Ren
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Surg Laparosc Endosc Percutan Tech 23:e235-6. 2013
    ..Symptoms achieved resolutions and the follow-up computed tomography scans revealed no intestinal fluid leakage. To our knowledge, this is the first report on this percutaneous endoscope-assisted glue procedure. ..
  20. doi request reprint Exogenous C3 protein enhances the adaptive immune response to polymicrobial sepsis through down-regulation of regulatory T cells
    Yujie Yuan
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, PR China
    Int Immunopharmacol 12:271-7. 2012
    ..It is still obscure how complement proteins promote T cell-mediated immune response during sepsis. The aim of this study is to investigate the role of exogenous C3 protein in the T-cell responses to sepsis...
  21. ncbi request reprint Antimicrobial properties of single-donor-derived, platelet-leukocyte fibrin for fistula occlusion: An in vitro study
    Xiuwen Wu
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Platelets 24:632-6. 2013
    ..This is the first study to demonstrate the antibacterial properties of single-unit PLF for fistula closure, presenting a new opportunity for glue sealing. ..
  22. doi request reprint The modified sandwich-vacuum package for fascial closure of the open abdomen in septic patients with gastrointestinal fistula
    Yujie Yuan
    Department of Gastrointestinal pancreatic Surgery, the First Affiliated Hospital of Sun Yat Sen University, Guangzhou, China
    J Trauma Acute Care Surg 75:266-72. 2013
    ..This retrospective study evaluated whether a modified sandwich-vacuum package (MSVP) improved fascial closure rate compared with the polypropylene mesh (PPM)-mediated method...
  23. doi request reprint Fish oil-supplemented parenteral nutrition prolongs survival while beneficially altering phospholipids' Fatty Acid composition and modulating immune function in rat sepsis
    Shougen Cao
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Shock 36:184-90. 2011
    ....
  24. pmc Complement depletion deteriorates clinical outcomes of severe abdominal sepsis: a conspirator of infection and coagulopathy in crime?
    Jianan Ren
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, P R China
    PLoS ONE 7:e47095. 2012
    ..The complement depletion commonly occurred during sepsis, but it was often underestimated compared with severe infection or coagulation dysfunction...
  25. doi request reprint Fibrin glue as the cell-delivery vehicle for mesenchymal stromal cells in regenerative medicine
    Xiuwen Wu
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    Cytotherapy 14:555-62. 2012
    ..This review focuses on the therapeutic potential of MSC with FG in bone defect reconstruction, cartilage and tendon injury repair, ligament, heart and nerve regeneration, and, furthermore, wound healing...
  26. doi request reprint LPS-stimulated RAW264.7 macrophage CAT-2-mediated l-arginine uptake and nitric oxide biosynthesis is inhibited by omega fatty acid lipid emulsion
    Qian Huang
    Research Institute of General Surgery, Jinling Hospital, Nanjing, China
    J Surg Res 179:e211-7. 2013
    ....
  27. ncbi request reprint Vasoactive intestinal peptide inhibits adhesion molecule expression in activated human colon serosal fibroblasts by preventing NF-kappaB activation
    Qingsong Tao
    Department of General Surgery, Jinling Hospital, Clinical School of Nanjing University, Nanjing, China
    J Surg Res 140:84-9. 2007
    ..The present study reports the effect of VIP on the expression of intracellular adhesion molecule-1 (ICAM-1) in IL-1beta-stimulated human colon SFs...
  28. doi request reprint The effect of different temporary abdominal closure materials on the growth of granulation tissue after the open abdomen
    Yujie Yuan
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    J Trauma 71:961-5. 2011
    ..This study was designed to evaluate the effects of different TAC materials and topically applied exogenous growth factors on the growth of granulation tissue covered on the wound areas after the open abdomen...
  29. pmc Mean platelet volume: a controversial marker of disease activity in Crohn's disease
    Song Liu
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, 305 East Zhongshan Road, Nanjing 210002, China
    Eur J Med Res 17:27. 2012
    ..We investigated and compared the capacity of mean platelet volume (MPV) and other inflammatory markers in detecting Crohn's disease (CD) activity and differentiating CD patients from healthy controls...
  30. doi request reprint Biochemical, mechanical, and morphological properties of a completely autologous platelet-rich wound sealant
    Xiuwen Wu
    Department of Surgery, Medical School of Nanjing University, China
    Blood Coagul Fibrinolysis 23:290-5. 2012
    ..The entirely autologous platelet-rich gel in the present study may get wide application in future practice after confirmation of its safety, efficiency, and economic benefits...
  31. doi request reprint Serum proteomic analysis from bacteremic and leucopenic rabbits
    Zheng Zhou
    Research Institute of General Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, PR China
    J Surg Res 171:749-54. 2011
    ..The identification of novel biomarkers for leucopenia in the context of bacteremia would facilitate early detection and provide insights into the identification of novel therapeutic targets...
  32. doi request reprint Exogenous C3 postpones complement exhaustion and confers organ protection in murine sepsis
    Yujie Yuan
    Department of Surgery, Jinling Hospital, Medical School of Nanjing University, Nanjing, China
    J Surg Res 168:e87-94. 2011
    ..The present study observed the dynamic levels of complement components in sepsis and evaluated the role of exogenous complement protein in outcomes. The relationship between complement and inflammatory cytokines was also investigated...
  33. ncbi request reprint Closure of gastrointestinal fistulas using fibrin sealant under fistulography
    Xinbo Wang
    Research Institute of General Surgery, Jinling Hospital, Nanjing, China
    Int Surg 90:223-6. 2005
    ..6 months). It is concluded that selective occlusion under fistulography is highly effective for gastrointestinal fistulas...