Jordi Rello

Summary

Publications

  1. ncbi request reprint Therapy of ventilator-associated pneumonia. A patient-based approach based on the ten rules of "The Tarragona Strategy"
    Alberto Sandiumenge
    Department of Critical Care, Joan XXIII University Hospital, University Rovira and Virgili, C Doctor Mallafré Guasch, 4, 43007, Tarragona, Spain
    Intensive Care Med 29:876-83. 2003
  2. pmc Influence of genetic variability at the surfactant proteins A and D in community-acquired pneumonia: a prospective, observational, genetic study
    M Isabel Garcia-Laorden
    Department of Immunology, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria 35010, Spain
    Crit Care 15:R57. 2011
  3. pmc Host adaptive immunity deficiency in severe pandemic influenza
    Jesus F Bermejo-Martin
    Infection and Immunity Unit, Hospital Clínico Universitario IECSCYL, Avda, Ramon y Cajal 3, 47005 Valladolid, Spain
    Crit Care 14:R167. 2010
  4. pmc Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza
    Jesus F Bermejo-Martin
    National Centre of Influenza, Hospital Clinico Universitario de Valladolid, Valladolid, Spain
    Crit Care 13:R201. 2009
  5. pmc Demographics, guidelines, and clinical experience in severe community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital University Rovira i Virgili, Pere Virgili Health Institut, CIBER Enfermedades Respiratorias CIBERES, Tarragona 43007, Spain
    Crit Care 12:S2. 2008
  6. doi request reprint Severity of pneumococcal pneumonia associated with genomic bacterial load
    Jordi Rello
    Critical Care Department, Hospital Universitari Joan XXIII, 43007 Tarragona, Spain
    Chest 136:832-40. 2009
  7. ncbi request reprint Severe Community-Acquired Pneumonia and PIRO: A New Paradigm of Management
    Jordi Rello
    Joan XXIII University Hospital, Carrer Mallafre Guasch 4, 43007 Tarragona, Spain
    Curr Infect Dis Rep 11:343-8. 2009
  8. pmc Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, CIBERes Enfermedades Respiratorias, IISPV, Mallafre Guasch 4, 43007 Tarragona, Spain
    Crit Care 13:R148. 2009
  9. doi request reprint Why mortality is increased in health-care-associated pneumonia: lessons from pneumococcal bacteremic pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Carrer Mallafre Guasch, 4, Tarragona 43007, Spain
    Chest 137:1138-44. 2010
  10. doi request reprint Activity of a silver-coated endotracheal tube in preclinical models of ventilator-associated pneumonia and a study after extubation
    Jordi Rello
    Joan XXIII University Hospital, CIBER Enfermedades Respiratorias CIBERES, University Rovira i Virgili, IISPV, Tarragona, Spain
    Crit Care Med 38:1135-40. 2010

Detail Information

Publications80

  1. ncbi request reprint Therapy of ventilator-associated pneumonia. A patient-based approach based on the ten rules of "The Tarragona Strategy"
    Alberto Sandiumenge
    Department of Critical Care, Joan XXIII University Hospital, University Rovira and Virgili, C Doctor Mallafré Guasch, 4, 43007, Tarragona, Spain
    Intensive Care Med 29:876-83. 2003
    ..The choice of initial antibiotic should be based on the patient's previous antibiotic exposure and comorbidities, and local antibiotic susceptibility patterns, which should be updated regularly...
  2. pmc Influence of genetic variability at the surfactant proteins A and D in community-acquired pneumonia: a prospective, observational, genetic study
    M Isabel Garcia-Laorden
    Department of Immunology, Hospital Universitario de Gran Canaria Dr Negrin, Las Palmas de Gran Canaria 35010, Spain
    Crit Care 15:R57. 2011
    ..We also studied the effect of genetic variability on SP-D serum levels...
  3. pmc Host adaptive immunity deficiency in severe pandemic influenza
    Jesus F Bermejo-Martin
    Infection and Immunity Unit, Hospital Clínico Universitario IECSCYL, Avda, Ramon y Cajal 3, 47005 Valladolid, Spain
    Crit Care 14:R167. 2010
    ..Pandemic A/H1N1/2009 influenza causes severe lower respiratory complications in rare cases. The association between host immune responses and clinical outcome in severe cases is unknown...
  4. pmc Th1 and Th17 hypercytokinemia as early host response signature in severe pandemic influenza
    Jesus F Bermejo-Martin
    National Centre of Influenza, Hospital Clinico Universitario de Valladolid, Valladolid, Spain
    Crit Care 13:R201. 2009
    ..We utilize here systemic cytokine and antibody levels in evaluating differences in early immune response in both mild and severe patients infected with nvH1N1...
  5. pmc Demographics, guidelines, and clinical experience in severe community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital University Rovira i Virgili, Pere Virgili Health Institut, CIBER Enfermedades Respiratorias CIBERES, Tarragona 43007, Spain
    Crit Care 12:S2. 2008
    ....
  6. doi request reprint Severity of pneumococcal pneumonia associated with genomic bacterial load
    Jordi Rello
    Critical Care Department, Hospital Universitari Joan XXIII, 43007 Tarragona, Spain
    Chest 136:832-40. 2009
    ..As viral load is useful in viral infections, we hypothesized that bacterial load may be associated with outcomes in patients with pneumococcal pneumonia...
  7. ncbi request reprint Severe Community-Acquired Pneumonia and PIRO: A New Paradigm of Management
    Jordi Rello
    Joan XXIII University Hospital, Carrer Mallafre Guasch 4, 43007 Tarragona, Spain
    Curr Infect Dis Rep 11:343-8. 2009
    ..The CAP-PIRO score is a new, simple tool stratifying patients in four categories and may be useful for early identification of patients who may benefit from adjunctive therapy...
  8. pmc Intensive care adult patients with severe respiratory failure caused by Influenza A (H1N1)v in Spain
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, CIBERes Enfermedades Respiratorias, IISPV, Mallafre Guasch 4, 43007 Tarragona, Spain
    Crit Care 13:R148. 2009
    ..We describe the clinical and epidemiologic characteristics of the first 32 persons reported to be admitted to the intensive care unit (ICU) due to influenza A (H1N1)v infection in Spain...
  9. doi request reprint Why mortality is increased in health-care-associated pneumonia: lessons from pneumococcal bacteremic pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Carrer Mallafre Guasch, 4, Tarragona 43007, Spain
    Chest 137:1138-44. 2010
    ..A cohort of patients with bacteremic Streptococcus pneumoniae pneumonia was reviewed to assess why mortality is higher in health-care-associated pneumonia (HCAP) than in community-acquired pneumonia (CAP)...
  10. doi request reprint Activity of a silver-coated endotracheal tube in preclinical models of ventilator-associated pneumonia and a study after extubation
    Jordi Rello
    Joan XXIII University Hospital, CIBER Enfermedades Respiratorias CIBERES, University Rovira i Virgili, IISPV, Tarragona, Spain
    Crit Care Med 38:1135-40. 2010
    ..To elucidate the mechanism of action of the silver-coated endotracheal tube in models of the early pathogenesis of ventilator-associated pneumonia...
  11. pmc Clinical review: primary influenza viral pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, CIBERes Enfermedades Respiratorias, IISPV, Tarragona, Spain
    Crit Care 13:235. 2009
    ..Ensuring an appropriate oxygenation and ventilation strategy, as well as prompt initiation of antiviral therapy, is essential in management...
  12. doi request reprint A European care bundle for prevention of ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Vall d Hebron University Hospital, Institut de Recerca Vall d Hebron UAB, CibeRes, Barcelona, Spain
    Intensive Care Med 36:773-80. 2010
    ..One recent approach to facilitating guideline implementation involves the use of care bundles...
  13. doi request reprint A European care bundle for management of ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Vall d Hebron University Hospital, Institut de Recerca Vall d Hebron Universitat Autònoma de Barcelona, CIBER Enfermedades Respiratorias CIBERES, Barcelona, Spain
    J Crit Care 26:3-10. 2011
    ..Although there is a wealth of guidance concerning the management of patients with ventilator-associated pneumonia (VAP), compliance with recommendations concerning optimal treatment practices is highly variable...
  14. doi request reprint Determinants of prescription and choice of empirical therapy for hospital-acquired and ventilator-associated pneumonia
    J Rello
    Critical Care Department, Vall d Hebron University Hospital, Vall d Hebron Institut de Recerca, Universitat Autonoma de Barcelona, Passeig de la Vall d Hebron, 119 129, 08035, Barcelona, Spain
    Eur Respir J 37:1332-9. 2011
    ..Across Europe, carbapenems were the antibiotic most prescribed for HAP/VAP...
  15. ncbi request reprint De-escalation therapy in ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Tarragona, Spain
    Crit Care Med 32:2183-90. 2004
    ..To evaluate de-escalation of antibiotic therapy in patients with ventilator-associated pneumonia...
  16. doi request reprint PIRO score for community-acquired pneumonia: a new prediction rule for assessment of severity in intensive care unit patients with community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Crit Care Med 37:456-62. 2009
    ....
  17. doi request reprint Prevalence, risk factors, and mortality for ventilator-associated pneumonia in middle-aged, old, and very old critically ill patients*
    Stijn Blot
    1Department of Internal Medicine, Ghent University, Ghent, Belgium 2Attikon University Hospital, Athens, Greece 3Critical Care Department, The Burns, Trauma, and Critical Care Research Center, The University of Queensland, Brisbane, QLD, Australia 4Critical Care Department, Nord University Hospital, Marseille, France 5Critical Care Department, General Hospital of Larisa, Larisa, Greece 6Critical Care Department, Clinics of Constance, Constance, Germany 7Department of Intensive Care, Mauriziano Hospital, Turin, Italy 8Critical Care Department, Vall d Hebron University Hospital, CibeRes, Universitat Autonoma de Barcelona, Barcelona, Spain
    Crit Care Med 42:601-9. 2014
    ..We investigated the epidemiology of ventilator-associated pneumonia in elderly ICU patients. More precisely, we assessed prevalence, risk factors, signs and symptoms, causative bacterial pathogens, and associated outcomes...
  18. doi request reprint Radiologic progression of pulmonary infiltrates predicts a worse prognosis in severe community-acquired pneumonia than bacteremia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, CIBER Enfermedades Respiratorias, Carrer Mallafre Guasch, Tarragona, Spain
    Chest 135:165-72. 2009
    ..The objective of this study was to investigate the relative importance of these two factors in the outcome of patients with severe CAP (sCAP)...
  19. doi request reprint Severe pandemic (H1N1)v influenza A infection: report on the first deaths in Spain
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, Spain
    Respirology 16:78-85. 2011
    ..The impact of pandemic influenza A (H1N1)v infection is still unknown but it is associated with a high case-fatality rate...
  20. doi request reprint First influenza season after the 2009 pandemic influenza: report of the first 300 ICU admissions in Spain
    A Rodriguez
    Hospital Joan XXIII, Critical Care Department, IISPV, URV, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Med Intensiva 35:208-16. 2011
    ..During the 2009 influenza pandemic, several reports were published, nevertheless, data on the clinical profiles of critically ill patients with the new virus infection during this second outbreak are still lacking...
  21. ncbi request reprint Risk factors for ventilator-associated pneumonia by Pseudomonas aeruginosa in presence of recent antibiotic exposure
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Anesthesiology 105:709-14. 2006
    ....
  22. doi request reprint Elevation of creatine kinase is associated with worse outcomes in 2009 pH1N1 influenza A infection
    Bárbara Borgatta
    Critical Care Department, Vall d Hebron University Hospital, Universitat Autonoma de Barcelona UAB, 08035, Barcelona, Spain
    Intensive Care Med 38:1152-61. 2012
    ..Current medical knowledge lacks specific information regarding creatine kinase (CK) elevation in influenza A pH1N1 (2009) infection...
  23. doi request reprint A randomized trial of dental brushing for preventing ventilator-associated pneumonia
    Angel Pobo
    Critical Care Department, Joan XXIII University Hospital, 43007 Tarragona, Spain
    Chest 136:433-9. 2009
    ..Poor oral hygiene is associated with respiratory pathogen colonization and secondary lung infection. The impact of adding electric toothbrushing to oral care in order to reduce ventilator-associated pneumonia (VAP) incidence is unknown...
  24. doi request reprint The ventilator-associated pneumonia PIRO score: a tool for predicting ICU mortality and health-care resources use in ventilator-associated pneumonia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 134:1208-16. 2008
    ..No score is available to assess severity and stratify mortality risk in ventilator-associated pneumonia (VAP). Our objective was to develop a severity assessment tool for VAP patients...
  25. ncbi request reprint Hospital-acquired pneumonia in the 21st century: a review of existing treatment options and their impact on patient care
    Despoina Koulenti
    Critical Care Department, Joan XXIII University Hospital Institut Pere Virgili, Mallafre Guasch, 4, 43007 Tarragona, Spain
    Expert Opin Pharmacother 7:1555-69. 2006
    ..The optimal duration of treatment is a matter of debate, but courses longer than 1 week are rarely justified...
  26. ncbi request reprint [Infection associated with the use of assisted-ventilation devices]
    Emili Diaz
    Servicio Medicina Intensiva, Hospital Universitari Joan XXIII, Tarragona, Spain
    Enferm Infecc Microbiol Clin 26:465-70. 2008
    ....
  27. ncbi request reprint Management of ventilator-associated pneumonia in a multidisciplinary intensive care unit: does trauma make a difference?
    Kemal Agbaht
    CIBER Enfermedades Respiratorias, University of Rovira and Virgili, Critical Care Department, Joan XXIII University Hospital, Institut Pere Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Intensive Care Med 33:1387-95. 2007
    ..Antibiotic exposure and timing of pneumonia onset influence ventilator-associated pneumonia (VAP) isolates. The first goal of this investigation was to evaluate whether trauma also influences prevalence of microorganisms...
  28. ncbi request reprint Clinical resolution in patients with suspicion of ventilator-associated pneumonia: a cohort study comparing patients with and without acute respiratory distress syndrome
    Loreto Vidaur
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Tarragona, Spain
    Crit Care Med 33:1248-53. 2005
    ..A secondary objective was to identify clinical variables that might be useful for monitoring response to therapy...
  29. ncbi request reprint Impact of diversity of antibiotic use on the development of antimicrobial resistance
    Alberto Sandiumenge
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili Institut Pere Virgili, Tarragona 43007, Spain
    J Antimicrob Chemother 57:1197-204. 2006
    ..To evaluate the impact of different antibiotic strategies on acquisition of resistant microorganisms...
  30. ncbi request reprint Prospective observational study of bacteremic pneumococcal pneumonia: Effect of discordant therapy on mortality
    Manel Lujan
    Pulmonary Department, Corporacio Parc Tauli, Sabadell, Barcelona, Spain
    Crit Care Med 32:625-31. 2004
    ..To evaluate the effect of discordant empirical therapy on outcome in bacteremic pneumococcal community-acquired pneumonia...
  31. pmc Bacteremia is an independent risk factor for mortality in nosocomial pneumonia: a prospective and observational multicenter study
    Monica Magret
    Critical Care Department, Vall d Hebron University Hospital, CibeRes, VHIR, Universitat Autonoma de Barcelona, Vall d Hebron St, Barcelona 08035, Spain
    Crit Care 15:R62. 2011
    ..The purpose of the study is to compare risk factors, pathogens and outcomes between bacteremic nosocomial pneumonia (B-NP) and nonbacteremic nosocomial pneumonia (NB-NP) episodes...
  32. ncbi request reprint Bacteremia in patients with ventilator-associated pneumonia is associated with increased mortality: A study comparing bacteremic vs. nonbacteremic ventilator-associated pneumonia
    Kemal Agbaht
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care Med 35:2064-70. 2007
    ..To assess whether bacteremic ventilator-associated pneumonia (B-VAP) differs in terms of risk factors, organisms, and outcomes from nonbacteremic VAP (NB-VAP)...
  33. doi request reprint Ventilator-associated pneumonia: impact of organisms on clinical resolution and medical resources utilization
    Loreto Vidaur
    Critical Care Department, Joan XXIII University Hospital and Pere Virgili Health Institute, Tarragona, Spain
    Chest 133:625-32. 2008
    ..The aim of this study was to evaluate the influence of organisms and their susceptibility to treatment on outcomes...
  34. ncbi request reprint Incidence, etiology, and outcome of nosocomial pneumonia in ICU patients requiring percutaneous tracheotomy for mechanical ventilation
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 124:2239-43. 2003
    ..To determine the epidemiology of pneumonia in patients with tracheotomy receiving short-term mechanical ventilation...
  35. doi request reprint Microbial aetiology of healthcare associated pneumonia in Spain: a prospective, multicentre, case-control study
    Eva Polverino
    Servicio de Pneumologia, Hospital Clinic i Provincial de Barcelona, IDIBAPS, Barcelona, Spain
    Thorax 68:1007-14. 2013
    ..Therefore, current American Thoracic Society/Infectious Diseases Society of America guidelines suggest a nosocomial antibiotic treatment for HCAP. Unfortunately, the scientific evidence supporting this is contradictory...
  36. pmc Acute kidney injury in critical ill patients affected by influenza A (H1N1) virus infection
    Ignacio Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital CIBER Enfermedades Respiratorias, URV, and IISPV, Mallafre i Guasch, ES 43007 Tarragona, Spain
    Crit Care 15:R66. 2011
    ..Little information exists about the impact of acute kidney injury (AKI) in critically ill patients with the pandemic 2009 influenza A (H1N1) virus infection...
  37. ncbi request reprint A 7-year study of severe hospital-acquired pneumonia requiring ICU admission
    Jordi Valles
    Critical Care Center, Hospital Sabadell, Institut Universitari Parc Tauli Universitat Autónoma de Barcelona, Parc Tauli s n, 08208, Barcelona, Spain
    Intensive Care Med 29:1981-8. 2003
    ..To examine the characteristics, prognostic factors, and outcome of patients with severe hospital-acquired pneumonia admitted to the ICU...
  38. doi request reprint Mortality in ICU patients with bacterial community-acquired pneumonia: when antibiotics are not enough
    Alejandro Rodriguez
    Critical Care Department, Pere Virgili Health Institut and CIBER Enfermedades Respiratorias, Joan XXIII University Hospital, Tarragona, Spain
    Intensive Care Med 35:430-8. 2009
    ..It remains uncertain why immunocompetent patients with bacterial community-acquired pneumonia (CAP) die, in spite of adequate antibiotics...
  39. doi request reprint Mortality and regional oxygen saturation index in septic shock patients: a pilot study
    Alejandro Rodriguez
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias, Tarragona, Spain
    J Trauma 70:1145-52. 2011
    ....
  40. doi request reprint Impact of nonexacerbated COPD on mortality in critically ill patients
    Alejandro Rodriguez
    Critical Care Department, Joan XXIII University Hospital, CIBERes Enfermedades Respiratorias, Universidad Rovira i Virgili IISPV, Tarragona, Spain
    Chest 139:1354-60. 2011
    ..The real contribution of nonexacerbated COPD to mortality has not been studied. The aim of our study was to evaluate the impact of nonexacerbated COPD on mortality in patients requiring mechanical ventilation (MV)...
  41. ncbi request reprint Nursing adherence with evidence-based guidelines for preventing ventilator-associated pneumonia
    Maite Ricart
    Critical Care Department, Joan XXIII University Hospital, Universitat Rovira i Virgili, Tarragona, Spain
    Crit Care Med 31:2693-6. 2003
    ..To review barriers to nursing adherence to nonpharmacologic evidence-based guidelines for preventing ventilator-associated pneumonia...
  42. ncbi request reprint Pneumonia caused by oxacillin-resistant Staphylococcus aureus treated with glycopeptides
    Jordi Rello
    Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care Med 33:1983-7. 2005
    ..To determine whether ventilator-associated pneumonia caused by oxacillin-resistant Staphylococcus aureus (VAP-ORSA) treated with glycopeptides is associated with an increased mortality rate...
  43. ncbi request reprint Reduced burden of bacterial airway colonization with a novel silver-coated endotracheal tube in a randomized multiple-center feasibility study
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Crit Care Med 34:2766-72. 2006
    ..To assess the feasibility and safety of the respiratory infection control (RIC) device, a silver-coated endotracheal tube, and its effect on bacterial burden in the airways...
  44. ncbi request reprint Management of ventilator-associated pneumonia caused by multiresistant bacteria
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili Institut Pere Virgili, Tarragona Spain
    Curr Opin Crit Care 13:45-50. 2007
    ..The inappropriate choice of antibiotics (in nearly one third of episodes) is the most important risk factor for death. Traditionally, a narrow-spectrum drug was used first, and the most potent drugs were reserved for subsequent use...
  45. ncbi request reprint Combination antibiotic therapy improves survival in patients with community-acquired pneumonia and shock
    Alejandro Rodriguez
    Intensive Care Unit, Joan XXIII University Hospital, Tarragona, Spain
    Crit Care Med 35:1493-8. 2007
    ..To assess whether combination antibiotic therapy improves outcome of severe community-acquired pneumonia in the subset of patients with shock...
  46. doi request reprint Ventilator-associated pneumonia in trauma patients is associated with lower mortality: results from EU-VAP study
    M Magret
    Critical Care Department, Sant Joan University Hospital, Reus, Spain
    J Trauma 69:849-54. 2010
    ..Differences in trauma patients developing ventilator-associated pneumonia (VAP) are described regarding etiology and risk factors associated. We aim to describe the differences in outcomes in trauma and nontrauma patients with VAP...
  47. ncbi request reprint Epidemiology and outcomes of ventilator-associated pneumonia in a large US database
    Jordi Rello
    University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Chest 122:2115-21. 2002
    ..To evaluate risk factors for ventilator-associated pneumonia (VAP), as well as its influence on in-hospital mortality, resource utilization, and hospital charges...
  48. doi request reprint Impact of obesity in patients infected with 2009 influenza A(H1N1)
    Emili Diaz
    Critical Care Department, Hospital Universitario Joan XXIII CIBER Enfermedades Respiratorias, URV, and IISPV, Carrer Dr, Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 139:382-6. 2011
    ..However, its role remains unclear. We evaluate the outcome of patients who are obese and infected with A(H1N1) in the ICU, determining whether obesity is a risk factor for mortality...
  49. ncbi request reprint Microbiological testing and outcome of patients with severe community-acquired pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 123:174-80. 2003
    ..The study documents the impact of microbiological investigations on therapeutic decisions and outcome in patients with severe community-acquired pneumonia (SCAP)...
  50. doi request reprint Impact of early oseltamivir treatment on outcome in critically ill patients with 2009 pandemic influenza A
    Alejandro Rodriguez
    Hospital Joan XXIII, Critical Care Department IISPV URV CIBERES, Tarragona, Spain
    J Antimicrob Chemother 66:1140-9. 2011
    ..The main objective of this study was to investigate the relationship between the timing of antiviral administration and intensive care unit (ICU) outcomes...
  51. ncbi request reprint Risk factors for pneumonia in the intubated patient
    Olga Diaz
    Critical Care Department, Hospital Doce de Octubre, Madrid, Spain
    Infect Dis Clin North Am 17:697-705. 2003
    ..This variable should be considered when stratifying patients for risk factor analysis and also in the design of clinical trials for VAP prophylaxis...
  52. doi request reprint Validation of predictors of adverse outcomes in hospital-acquired pneumonia in the ICU
    Mariano Esperatti
    Servei de Pneumologia, Institut Clinic del Torax, Hospital Clinic, IDIBAPS, Universitat de Barcelona, Barcelona, Spain
    Crit Care Med 41:2151-61. 2013
    ..To validate a set of predictors of adverse outcomes in patients with ICU-acquired pneumonia in relation to clinically relevant assessment at 28 days...
  53. doi request reprint Corticosteroid therapy in patients with primary viral pneumonia due to pandemic (H1N1) 2009 influenza
    Emili Diaz
    Critical Care Department, Hospital Sant Joan Despí Moisès Broggi, Jacint Verdaguer, 90, 08970 Sant Joan Despí, Barcelona, CibeRes, IISPV, Spain
    J Infect 64:311-8. 2012
    ..The objective of this study was to assess the effect on survival of corticosteroid therapy in patients with pandemic (H1N1) 2009 influenza...
  54. doi request reprint The spectrum of pneumococcal empyema in adults in the early 21st century
    Joaquin Burgos
    Infectious Diseases Department, Universitat Autonoma de Barcelona, Barcelona, Spain
    Clin Infect Dis 53:254-61. 2011
    ..Our objective was to describe the risk factors for pneumococcal empyema in adults and to analyze the differences in the incidence, disease characteristics, and serotype distribution between the pre- and post-PCV7 eras...
  55. ncbi request reprint C-reactive protein correlates with bacterial load and appropriate antibiotic therapy in suspected ventilator-associated pneumonia
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Crit Care Med 36:166-71. 2008
    ....
  56. doi request reprint Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection
    I Martin-Loeches
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias CIBERES, Tarragona, Spain
    Intensive Care Med 37:272-83. 2011
    ..Early use of corticosteroids in patients affected by pandemic (H1N1)v influenza A infection, although relatively common, remains controversial...
  57. ncbi request reprint Clinical approach to the patient with suspected ventilator-associated pneumonia
    Loreto Vidaur
    Critical Care Department, University Rovira and Virgili Institut Pere Virgili, Joan XXIII University Hospital, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Respir Care 50:965-74; discussion 974. 2005
    ..Optimal management should be based on a strategy combining early high doses of an effective agent for a short period of time, which is then simplified in the light of microbiologic information...
  58. doi request reprint PAI-1 gene: pharmacogenetic association of 4G/4G genotype with bleeding after cardiac surgery--pilot study
    Gonzalo Sirgo
    Intensive Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Pere Virgili Health Institute, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Eur J Anaesthesiol 26:404-11. 2009
    ..To investigate whether the 4G/4G genotype of the PAI-1 gene is associated with bleeding after cardiac surgery and whether it may influence the use of antifibrinolytic drugs...
  59. ncbi request reprint Pneumonia in the intensive care unit
    Jordi Rello
    Critical Care Department, Joan XXII University Hospital, University Rovira i Virgili, Taragona, Spain
    Crit Care Med 31:2544-51. 2003
    ..To update the state-of-the-art on pneumonia in adult patients in the intensive care unit (ICU), with special emphasis on new developments in management...
  60. doi request reprint Risk factors for respiratory failure in pneumococcal pneumonia: the importance of pneumococcal serotypes
    Joaquin Burgos
    Hospital Universitari Vall d Hebron, Vall d Hebron Research Institute VHIR, Universitat Autonoma de Barcelona, Barcelona
    Eur Respir J 43:545-53. 2014
    ..22-10.28). In conclusion, respiratory failure is a frequent complication of pneumococcal pneumonia and causes high morbidity and mortality. Pneumococcal serotypes 3, 19A and 19F are the main risk factors for this complication. ..
  61. ncbi request reprint Nosocomial lung infections in adult intensive care units
    Gonzalo Hernandez
    Critical Care Department, 12, de Octubre University Hospital, University Complutense, Madrid, Spain
    Microbes Infect 6:1004-14. 2004
    ..Nosocomial pneumonias are often difficult to treat due to antibiotic-resistant bacteria. Antibiotic policies are crucial in avoiding a progression in antibiotic resistance...
  62. doi request reprint Severe sepsis mortality prediction with relevance vector machines
    Vicent J Ribas
    SOCO Research Group, Llenguatges i Sistemes Informàtics, Universitat Politecnica de Catalunya, Barcelona, Spain
    Conf Proc IEEE Eng Med Biol Soc 2011:100-3. 2011
    ..The reported results show that it outperforms in terms of accuracy alternative techniques currently in use, while simultaneously assessing the relative impact of individual pathology indicators...
  63. doi request reprint Effect of antibiotic diversity on ventilator-associated pneumonia caused by ESKAPE Organisms
    Alberto Sandiumenge
    Critical Care Department, Joan XXIII University Hospital, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Chest 140:643-51. 2011
    ....
  64. doi request reprint New treatment options for infections caused by multiresistant strains of Pseudomonas aeruginosa and other nonfermenting gram-negative bacilli
    Anna Sanchez
    Critical Care Department, Vall d Hebron University Hospital, Barcelona, Spain
    Semin Respir Crit Care Med 32:151-8. 2011
    ..Future options include immunotherapy or the continuous infusion of antibiotics. It is also important to emphasize the rational use of antibiotics to diminish the appearance of multiresistant pathogens...
  65. pmc Bench-to-bedside review: Therapeutic options and issues in the management of ventilator-associated bacterial pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Tarragona, Spain
    Crit Care 9:259-65. 2005
    ..More active, less toxic antibacterial agents are still needed, in particular to combat problematic pathogens such as multiresistant Gram-negative bacilli and resistant Gram-positive organisms (e.g. methicillin-resistant S aureus)...
  66. ncbi request reprint Why do physicians not follow evidence-based guidelines for preventing ventilator-associated pneumonia?: a survey based on the opinions of an international panel of intensivists
    Jordi Rello
    Critical Care Department, University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Chest 122:656-61. 2002
    ..Adherence to clinical practice guidelines is highly variable. Our objective was to review barriers to physicians' adherence to evidence-based guidelines (EBGs) for preventing ventilator-associated pneumonia (VAP)...
  67. ncbi request reprint Ventilator-associated pneumonia: issues related to the artificial airway
    Emili Diaz
    Critical Care Department, University Rovira and Virgili Institut Pere Virgili, Joan XXIII University Hospital, Carrer Dr Mallafre Guasch 4, 43007 Tarragona, Spain
    Respir Care 50:900-6; discussion 906-9. 2005
    ..As many studies suggest that incidence of VAP is highly dependent on the strategies of airway management, health care workers should be alerted to issues related to the artificial airway...
  68. ncbi request reprint Etiology of ventilator-associated pneumonia
    Jordi Rello
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Carrer Dr Mallafre Guasch 4, Tarragona 43007, Spain
    Clin Chest Med 26:87-95. 2005
    ..The discussion herein analyzes these aspects, placing particular emphasis on risk factors, attributable mortality, resistance, and the implications for management...
  69. ncbi request reprint Effects of high-dose of intravenous immunoglobulin and antibiotics on survival for severe sepsis undergoing surgery
    Alejandro Rodriguez
    Intensive Care Department of Joan XXIII University Hospital University Rovira and Virgili and Institut Pere Virgili, Tarragona, Spain
    Shock 23:298-304. 2005
    ..We conclude that IVIG administration, when used in combination with adequate antibiotics, improved the survival of surgical ICU patients with intra-abdominal sepsis. The initial choice of antibiotic has a dramatic impact on outcome...
  70. doi request reprint Healthcare-associated infections. A useful concept?
    Manel Lujan
    Pneumology Service, Hospital de Sabadell, Corporacio Parc Tauli, Universitat Autonoma de Barcelona, Sabadell, Spain
    Curr Opin Crit Care 15:419-24. 2009
    ..Although described originally in bacteremia, the concept has also been applied to other infections such as pneumonia and endocarditis...
  71. ncbi request reprint Oral care practices in intensive care units: a survey of 59 European ICUs
    Jordi Rello
    Joan XXIII University Hospital, Critical Care Department, Mallafre Guasch 4, 43007 Tarragona, Spain
    Intensive Care Med 33:1066-70. 2007
    ..To explore the type and frequency of oral care practices in European ICUs and the attitudes, beliefs, and knowledge of health care workers...
  72. doi request reprint Antibiotic dosing in multiple organ dysfunction syndrome
    Marta Ulldemolins
    Burns, Trauma and Critical Care Research Centre, The University of Queensland, Brisbane, QLD, Australia
    Chest 139:1210-20. 2011
    ..Thereafter, maintenance dosing must be guided by drug clearance and adjusted to the degree of organ dysfunction...
  73. doi request reprint Diagnosis of ventilator-associated pneumonia: is there a gold standard and a simple approach?
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBER Enfermedades Respiratorias, Tarragona, Spain
    Curr Opin Infect Dis 21:174-8. 2008
    ..Recent findings in diagnosis are reviewed here...
  74. doi request reprint Management of ventilator-associated pneumonia
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, University Rovira i Virgili, IISPV, CIBER Enfermedades Respiratorias, Carrer Mallafre Guasch 4, Tarragona 43007, Spain
    Infect Dis Clin North Am 23:521-33. 2009
    ..In recent years, a more dynamic approach has evolved, updating local epidemiology, evaluating VAP and diagnostic tools every day, and assessing host response using clinical and biochemical parameters...
  75. doi request reprint Emerging drugs for pneumococcal pneumonia
    Vicenc Falco
    Infectious Diseases Department, Hospital Universitari Vall d Hebron, Universitat Autonoma de Barcelona, Spain
    Expert Opin Emerg Drugs 16:459-77. 2011
    ..However, concerns about the evolution of antibiotic resistance justify the review of new indications for known antibiotics and the development of new products...
  76. pmc The simple and the simpler in pneumonia diagnosis
    Thiago Lisboa
    Critical Care Department, Joan XXIII University Hospital, University Rovira and Virgili, Institut Pere Virgili, CIBERes Enfermedades Respiratorias, Carrer Mallafre Guasch, 4 43007, Tarragona, Spain
    Crit Care 11:140. 2007
    ....
  77. ncbi request reprint Association between 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene with stroke or encephalopathy after cardiac surgery
    Gonzalo Sirgo
    Intensive Care Department, Joan XXIII University Hospital, University Rovira i Virgili, Institut Pere Virgili, Mallafre Guasch N 4, 43007, Tarragona, Spain
    Intensive Care Med 32:668-75. 2006
    ....
  78. ncbi request reprint Top ten list in antibiotic policy in the ICU
    Emili Diaz
    Critical Care Department, Joan XXIII University Hospital, Tarragona, Spain
    Chest 122:712-4. 2002
  79. ncbi request reprint Prevention of infection in the intensive care unit: current advances and opportunities for the future
    Carmen Lorente
    Critical Care Department, University Hospital Joan XXIII, University Rovira and Virgili, Tarragona, Spain
    Curr Opin Crit Care 8:461-4. 2002
    ..Potential measures of control should focus on the patient, the microorganisms, and the device. A number of recent studies addressing these issues have been published and will be reviewed in this article...
  80. ncbi request reprint Effect of enriched thioglycolate on direct examination of respiratory specimens and guiding initial empirical therapy in intubated patients with pneumonia: a prospective, randomized study
    Jordi Rello
    Intensive Care Department, Hospital de Sabadell, Sabadell, Barcelona, Spain
    Crit Care Med 30:311-4. 2002
    ..To evaluate the use of enriched thioglycolate as a transport medium of protected specimen brush samples, in particular its value in direct examination of respiratory specimens and in guiding initial antibiotic prescription...