Jurgen Rehm

Summary

Publications

  1. ncbi Modes and impact of coercive inpatient treatment for drug-related conditions in Switzerland
    Esther Grichting
    Addiction Research Institute, Zurich, Switzerland
    Eur Addict Res 8:78-83. 2002
  2. ncbi Alcohol as a risk factor for global burden of disease
    Jurgen Rehm
    Addiction Research Institute, Zurich, Switzerland
    Eur Addict Res 9:157-64. 2003
  3. ncbi Alcohol accounts for a high proportion of premature mortality in central and eastern Europe
    Jurgen Rehm
    Cancer Center and Institute of Oncology, Cancer Epidemiology and Prevention Division, Warsaw, Poland
    Int J Epidemiol 36:458-67. 2007
  4. ncbi Illegal drug-attributable morbidity in Canada 2002
    Svetlana Popova
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Drug Alcohol Rev 26:251-63. 2007
  5. doi Method for moderation: measuring lifetime risk of alcohol-attributable mortality as a basis for drinking guidelines
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Canada
    Int J Methods Psychiatr Res 17:141-51. 2008
  6. pmc 12-month follow-up of an exploratory 'brief intervention' for high-frequency cannabis users among Canadian university students
    Benedikt Fischer
    Centre for Applied Research in Mental Health and Addictions, Faculty of Health Sciences, Simon Fraser University, 2400, 515 West Hastings St, Vancouver, BC, V6B 5K3, Canada
    Subst Abuse Treat Prev Policy 7:15. 2012
  7. pmc Global burden of injuries attributable to alcohol consumption in 2004: a novel way of calculating the burden of injuries attributable to alcohol consumption
    Kevin D Shield
    Centre for Addiction and Mental Health CAMH, Toronto, Canada
    Popul Health Metr 10:9. 2012
  8. pmc Assessing the prevalence of non-medical prescription opioid use in the Canadian general adult population: evidence of large variation depending on survey questions used
    Kevin D Shield
    Centre for Addiction and Mental Health CAMH, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada
    BMC Psychiatry 13:6. 2013
  9. pmc Determining the best population-level alcohol consumption model and its impact on estimates of alcohol-attributable harms
    Tara Kehoe
    Centre for Addiction and Mental Health CAMH, Toronto, Canada
    Popul Health Metr 10:6. 2012
  10. doi Different guidelines for different countries? On the scientific basis of low-risk drinking guidelines and their implications
    Jurgen Rehm
    Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada
    Drug Alcohol Rev 31:156-61. 2012

Collaborators

Detail Information

Publications117 found, 100 shown here

  1. ncbi Modes and impact of coercive inpatient treatment for drug-related conditions in Switzerland
    Esther Grichting
    Addiction Research Institute, Zurich, Switzerland
    Eur Addict Res 8:78-83. 2002
    ..Two forms of institutionalized pressure to treatment can be distinguished in Switzerland: civil commitment and court referral. In court referral, the referred patient has the right to refuse treatment...
  2. ncbi Alcohol as a risk factor for global burden of disease
    Jurgen Rehm
    Addiction Research Institute, Zurich, Switzerland
    Eur Addict Res 9:157-64. 2003
    ..To make quantitative estimates of the burden of disease attributable to alcohol in the year 2000 on a global basis...
  3. ncbi Alcohol accounts for a high proportion of premature mortality in central and eastern Europe
    Jurgen Rehm
    Cancer Center and Institute of Oncology, Cancer Epidemiology and Prevention Division, Warsaw, Poland
    Int J Epidemiol 36:458-67. 2007
    ..Russia was added as an external comparator...
  4. ncbi Illegal drug-attributable morbidity in Canada 2002
    Svetlana Popova
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Drug Alcohol Rev 26:251-63. 2007
    ..6. A mixture of prevention and harm reduction measures is proposed to reduce the burden of morbidity associated with drug use...
  5. doi Method for moderation: measuring lifetime risk of alcohol-attributable mortality as a basis for drinking guidelines
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Canada
    Int J Methods Psychiatr Res 17:141-51. 2008
    ....
  6. pmc 12-month follow-up of an exploratory 'brief intervention' for high-frequency cannabis users among Canadian university students
    Benedikt Fischer
    Centre for Applied Research in Mental Health and Addictions, Faculty of Health Sciences, Simon Fraser University, 2400, 515 West Hastings St, Vancouver, BC, V6B 5K3, Canada
    Subst Abuse Treat Prev Policy 7:15. 2012
    ..The present study examined 12-month follow-up outcomes for BIs in a cohort of young Canadian high-frequency cannabis users where select short-term effects (3 months) had previously been assessed and demonstrated...
  7. pmc Global burden of injuries attributable to alcohol consumption in 2004: a novel way of calculating the burden of injuries attributable to alcohol consumption
    Kevin D Shield
    Centre for Addiction and Mental Health CAMH, Toronto, Canada
    Popul Health Metr 10:9. 2012
    ..abstract:..
  8. pmc Assessing the prevalence of non-medical prescription opioid use in the Canadian general adult population: evidence of large variation depending on survey questions used
    Kevin D Shield
    Centre for Addiction and Mental Health CAMH, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada
    BMC Psychiatry 13:6. 2013
    ....
  9. pmc Determining the best population-level alcohol consumption model and its impact on estimates of alcohol-attributable harms
    Tara Kehoe
    Centre for Addiction and Mental Health CAMH, Toronto, Canada
    Popul Health Metr 10:6. 2012
    ..abstract:..
  10. doi Different guidelines for different countries? On the scientific basis of low-risk drinking guidelines and their implications
    Jurgen Rehm
    Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada
    Drug Alcohol Rev 31:156-61. 2012
    ..Acceptable thresholds will be different if the risk is to oneself or to others...
  11. pmc Combining best evidence: a novel method to calculate the alcohol-attributable fraction and its variance for injury mortality
    Benjamin J Taylor
    Social and Epidemiological Research Department, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    BMC Public Health 11:265. 2011
    ..For this analysis, the Canadian population in 2005 was used as the reference population...
  12. pmc Alcohol and cannabis use as risk factors for injury--a case-crossover analysis in a Swiss hospital emergency department
    Gerhard Gmel
    Alcohol Treatment Center, Lausanne University Hospital, Lausanne, Switzerland
    BMC Public Health 9:40. 2009
    ....
  13. pmc A systematic review of longitudinal studies on the association between depression and smoking in adolescents
    Michael O Chaiton
    Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
    BMC Public Health 9:356. 2009
    ..It is well-established that smoking and depression are associated in adolescents, but the temporal ordering of the association is subject to debate...
  14. pmc Estimating uncertainty of alcohol-attributable fractions for infectious and chronic diseases
    Gerrit Gmel
    Centre for Addiction and Mental Health CAMH 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada
    BMC Med Res Methodol 11:48. 2011
    ..This paper presents a systematic method to compute the 95% confidence intervals of alcohol-attributable fractions (AAFs) with exposure and risk relations stemming from different sources...
  15. pmc A novel nonparametric approach for estimating cut-offs in continuous risk indicators with application to diabetes epidemiology
    Jens Klotsche
    Institute of Clinical Psychology and Psychotherapy, Technische Universitaet Dresden, Germany
    BMC Med Res Methodol 9:63. 2009
    ..The cut-off corresponding to the Youden-Index is often applied in epidemiology and biomedical literature for dichotomizing a continuous risk indicator...
  16. pmc Cancer risk assessment of ethyl carbamate in alcoholic beverages from Brazil with special consideration to the spirits cachaça and tiquira
    Dirk W Lachenmeier
    Departamento de Neurologia, Psicologia e Psiquiatria, Botucatu Medical School UNESP, Sao Paulo State University, CP 540 Distrito Rubiao Junior, 18618 970 Botucatu, Sao Paulo, Brazil
    BMC Cancer 10:266. 2010
    ..15 mg/l. This study aims to estimate human exposure in Brazil and provide a quantitative risk assessment...
  17. ncbi Alcohol consumption and public health in Russia
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, ON, Canada M51 2S1
    Lancet 369:1975-6. 2007
  18. ncbi Comparative quantification of alcohol exposure as risk factor for global burden of disease
    Jurgen Rehm
    Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada
    Int J Methods Psychiatr Res 16:66-76. 2007
    ..The methodology is applied to estimate global alcohol exposure for the year 2002. Finally, assumptions and potential problems of the approach are discussed...
  19. ncbi The costs of alcohol, illegal drugs, and tobacco in Canada, 2002
    Jurgen Rehm
    Centre for Addiction and Mental Health, 33 Russell Street, Room 2035B, Toronto, Ontario M5S 2S1, Canada
    J Stud Alcohol Drugs 68:886-95. 2007
    ..The aim of this study was to estimate costs attributable to substance use and misuse in Canada in 2002...
  20. ncbi Avoidable burden of disease: conceptual and methodological issues in substance abuse epidemiology
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Ontario Canada
    Int J Methods Psychiatr Res 15:181-91. 2006
    ..The impetus to begin refining methods to obtain better starting points for estimating avoidable burden of disease is obvious and should be carried through in order to see real changes through evidence-based policy and intervention...
  21. ncbi Key future research questions on mediators and moderators of behaviour change processes for substance abuse
    Jurgen Rehm
    Epidemiological Research Unit, Institute of Clinical, Diagnostic and Differential Psychology, Technische Universitat Dresden, Dresden, Germany
    Int J Methods Psychiatr Res 17:S83-7. 2008
    ..This may include improved forms of international funding of groups of researchers from different countries, where each national group conducts a specific part of an integrated proposal...
  22. ncbi Global burden of disease from alcohol, illicit drugs and tobacco
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Drug Alcohol Rev 25:503-13. 2006
    ..The burden of disease attributable to the use of legal substances clearly outweighed the use of illegal drugs. A large part of the substance-attributable burden would be avoidable if known effective interventions were implemented...
  23. pmc Estimating chronic disease deaths and hospitalizations due to alcohol use in Canada in 2002: implications for policy and prevention strategies
    Jurgen Rehm
    Public Health and Regulatory Policies, Centre for Addiction and Mental Health, University of Toronto, 33 Russell St, Room 2035, Toronto, Ontario, Canada M5S 2S1
    Prev Chronic Dis 3:A121. 2006
    ..Alcohol consumption is a factor that increases risk of chronic disease. This study estimates various indicators of alcohol-attributable premature chronic-disease morbidity and mortality for Canada in 2002...
  24. ncbi Alcohol-attributable mortality and potential years of life lost in Canada 2001: implications for prevention and policy
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Canada
    Addiction 101:373-84. 2006
    ..Alcohol is one of the most important risk factors for burden of disease...
  25. ncbi Alcohol consumption and burden of disease in the Americas: implications for alcohol policy
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Canada
    Rev Panam Salud Publica 18:241-8. 2005
    ..To describe patterns of alcohol consumption in the Americas, to estimate the burden of disease attributable to alcohol in the year 2000, and to suggest implications for policies to reduce alcohol-related disease burden...
  26. ncbi School matters: drinking dimensions and their effects on alcohol-related problems among Ontario secondary school students
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Canada
    Alcohol Alcohol 40:569-74. 2005
    ..To test the hypotheses that average volume of alcohol consumption and patterns of drinking, each influence alcohol-related problems and that both act at individual and aggregate levels...
  27. ncbi Mortality in heroin-assisted treatment in Switzerland 1994-2000
    Jurgen Rehm
    Addiction Research Institute, Konradstr 32, CH 8031 Zurich, Switzerland
    Drug Alcohol Depend 79:137-43. 2005
    ..A major goal of heroin-assisted treatment in Switzerland has been to reduce the drug-related mortality of heroin users. Therefore, a continuous monitoring of deaths under treatment is essential...
  28. pmc Should heroin be prescribed to heroin misusers? Yes
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, ON M5S 2S1, Canada
    BMJ 336:70. 2008
  29. pmc Public alcohol policy: current directions and new opportunities
    J Rehm
    Public Health and Regulatory Policies, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Clin Pharmacol Ther 83:640-3. 2008
    ..In this overview we identify the pathways in the relationship between alcohol policy and addiction, present the empirical evidence, and draw conclusions. Special emphasis will be put on treatment policy...
  30. doi Indicators of alcohol consumption and attributable harm for monitoring and surveillance in European Union countries
    Jurgen Rehm
    Institute for Clinical Psychology and Psychotherapy, TU Dresden, Dresden, Germany mail
    Addiction 106:4-10. 2011
    ..The aim of this paper is to propose a system of indicators for alcohol consumption and attributable harm which can be used as an over-time monitoring tool at the country level as well as for comparisons between countries...
  31. pmc Developing a method to derive alcohol-attributable fractions for HIV/AIDS mortality based on alcohol's impact on adherence to antiretroviral medication
    Gerrit Gmel
    Centre for Addiction and Mental Health CAMH, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada
    Popul Health Metr 9:5. 2011
    ..abstract:..
  32. doi Alcohol as a risk factor for liver cirrhosis: a systematic review and meta-analysis
    Jurgen Rehm
    Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada
    Drug Alcohol Rev 29:437-45. 2010
    ..To address these questions and to provide a quantitative assessment of the association between alcohol intake and risk of liver cirrhosis, we conducted a systematic review and meta-analysis of cohort and case-control studies...
  33. doi Unrecorded consumption, quality of alcohol and health consequences
    Jurgen Rehm
    Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada
    Drug Alcohol Rev 29:426-36. 2010
    ..This contribution aims to examine systematically the evidence on the impact of the quality of unrecorded alcohol products on health consequences...
  34. doi Addiction Research Centres and the Nurturing of Creativity. Substance abuse research in a modern health care centre: the case of the Centre for Addiction and Mental Health
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, ON, Canada
    Addiction 106:689-97. 2011
    ..We argue for the continuation of this successful model of integrating basic, epidemiological, clinical, health service and prevention research under the roof of a health centre...
  35. pmc The relation between different dimensions of alcohol consumption and burden of disease: an overview
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Canada
    Addiction 105:817-43. 2010
    ....
  36. pmc Statistical modeling of volume of alcohol exposure for epidemiological studies of population health: the US example
    Jurgen Rehm
    Centre for Addiction and Mental Health CAMH, 33 Russell Street, Toronto, Ontario, M5S 2S1, Canada
    Popul Health Metr 8:3. 2010
    ..As both sources have significant problems, this paper presents an approach that triangulates information from both sources into disaggregated estimates in line with the overall level of per capita consumption...
  37. pmc Valuation of health states in the US study to establish disability weights: lessons from the literature
    Jurgen Rehm
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Int J Methods Psychiatr Res 19:18-33. 2010
    ..The US study received the collaboration of experts from more than 20 institutes of the National Institutes of Health and of the Centers for Disease Control and Prevention. First results will be available by the end of this year...
  38. pmc The association between alcohol use, alcohol use disorders and tuberculosis (TB). A systematic review
    Jurgen Rehm
    Public Health and Regulatory Policies, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    BMC Public Health 9:450. 2009
    ..8%) and 2.2% of global burden of disease (men 2.7%; women 1.7%). The present work portrays accumulated evidence on the association between alcohol consumption and TB with the aim to clarify the nature of the relationship...
  39. ncbi Global burden of disease and injury and economic cost attributable to alcohol use and alcohol-use disorders
    Jurgen Rehm
    Public Health and Regulatory Policies, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Lancet 373:2223-33. 2009
    ..Overall, we conclude that alcohol consumption is one of the major avoidable risk factors, and actions to reduce burden and costs associated with alcohol should be urgently increased...
  40. pmc Are lifetime abstainers the best control group in alcohol epidemiology? On the stability and validity of reported lifetime abstention
    J Rehm
    Centre for Addiction and Mental Health, 33 Russell Street, Room 2035, Toronto, Ontario M5S2S1, Canada
    Am J Epidemiol 168:866-71. 2008
    ..Establishing multiple measurement points and including irregular lifetime light drinkers with lifetime abstainers as the comparison group are recommended for future epidemiologic studies...
  41. ncbi Problematic drug use and drug use disorders in EU countries and Norway: an overview of the epidemiology
    Jurgen Rehm
    ISF Addiction Research Institute, Konradstr 32, CH 8031 Zurich, Switzerland
    Eur Neuropsychopharmacol 15:389-97. 2005
    ..To estimate the prevalence of drug use disorders in the European Union and Norway...
  42. ncbi Alcohol use disorders in EU countries and Norway: an overview of the epidemiology
    Jurgen Rehm
    Addiction Research Institute, Zurich, Switzerland
    Eur Neuropsychopharmacol 15:377-88. 2005
    ..rural and AUD prevalence. The discussion highlights potential explanations for the high variability of prevalence between countries, and the fact, that AUD constitute only a small part of all alcohol-related harm...
  43. doi Epidemiology and alcohol policy in Europe
    Jurgen Rehm
    Epidemiological Research Unit, Technische Universitat Dresden, Klinische Psychologie and Psychotherapie, Dresden, Germany mail
    Addiction 106:11-9. 2011
    ..To describe three aspects of the epidemiology of alcohol-attributable deaths in Europe, dose, demography and place, and to illustrate how such knowledge can better be used to inform alcohol policy formulation and implementation...
  44. ncbi Alcohol consumption and total mortality/morbidity-definitions and methodological implications
    Jurgen Rehm
    Addiction Research Institute Zurich, Switzerland
    Best Pract Res Clin Gastroenterol 17:497-505. 2003
    ....
  45. ncbi The global distribution of average volume of alcohol consumption and patterns of drinking
    Jurgen Rehm
    Addiction Research Institute, Zurich, Switzerland
    Eur Addict Res 9:147-56. 2003
    ..To make quantitative estimates on a global basis of exposure of disease-relevant dimensions of alcohol consumption, i.e. average volume of alcohol consumption and patterns of drinking...
  46. ncbi The relationship of average volume of alcohol consumption and patterns of drinking to burden of disease: an overview
    Jurgen Rehm
    Addiction Research Institute, Zurich, Switzerland
    Addiction 98:1209-28. 2003
    ..AAFs were estimated as a function of prevalence of exposure and relative risk, or from combining the aggregate multi-level analyses with prevalence data...
  47. ncbi Feasibility, safety, and efficacy of injectable heroin prescription for refractory opioid addicts: a follow-up study
    J Rehm
    Addiction Research Institute, CH 8031, Zurich, Switzerland
    Lancet 358:1417-23. 2001
    ..Heroin-assisted substitution treatment for severely opioid-dependent drug users has been available in Switzerland since 1994. Our aim was to ascertain the feasibility, safety, and efficacy of this treatment...
  48. ncbi A comparison of serum total cholesterol levels and their determinants between the Federal Republic of Germany and the United States
    J Rehm
    Robert Koch Institute, Berlin, Germany
    Eur J Epidemiol 16:669-75. 2000
    ..Adjustment for differences in alcohol intake had negligible effects on reducing the differences in mean non-HDL cholesterol...
  49. pmc Illicit opioid use in Canada: comparing social, health, and drug use characteristics of untreated users in five cities (OPICAN study)
    Benedikt Fischer
    University of Toronto and Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Urban Health 82:250-66. 2005
    ..Differentiated interventions are required...
  50. pmc Smoking-attributable morbidity: acute care hospital diagnoses and days of treatment in Canada, 2002
    Dolly Baliunas
    Public Health Sciences Department, University of Toronto, Toronto, Canada
    BMC Public Health 7:247. 2007
    ..Smoking is one of the most important risk factors for burden of disease. Our objective was to estimate the number of hospital diagnoses and days of treatment attributable to smoking for Canada, 2002...
  51. ncbi Alcohol-attributable morbidity and resulting health care costs in Canada in 2002: recommendations for policy and prevention
    Benjamin Taylor
    Centre for Addiction and Mental Health, Toronto, Ontario, M5S 2S1, Canada
    J Stud Alcohol Drugs 68:36-47. 2007
    ..The purpose of this article was to estimate the number of hospitalizations, hospital days, and the resulting costs attributable to alcohol for Canada in 2002...
  52. ncbi Prevalence and associated factors of hepatitis C infection (HCV) in a multi-site Canadian population of illicit opioid and other drug users (OPICAN)
    Michelle Firestone Cruz
    Centre for Addiction and Mental Health, Toronto, ON
    Can J Public Health 98:130-3. 2007
    ..Using data from a multi-site cohort study of illicit opioid users in five Canadian cities (OPICAN), this paper explores the prevalence and predictors of HCV status in this high-risk population...
  53. ncbi Dosage regimes in the prescription of heroin and other narcotics to chronic opioid addicts in Switzerland--Swiss national cohort study
    Patrick Gschwend
    Addiction Research Institute, University of Zurich, Zurich, Switzerland
    Eur Addict Res 10:41-8. 2004
    ..This contribution analyses the course of dose levels during the treatment period...
  54. ncbi Using latent class analysis (LCA) to analyze patterns of drug use in a population of illegal opioid users
    Neerav Monga
    Centre for Addiction and Mental Health, Toronto, Ontario M5S 2S1, Canada
    Drug Alcohol Depend 88:1-8. 2007
    ..The objective of this paper is to empirically determine a categorization of illegal opioid users in Canada in order to describe and analyze drug use patterns within this population...
  55. doi Gender differences in health-related quality of life among cannabis users: results from the National Epidemiologic Survey on Alcohol and Related Conditions
    Shaul Lev-Ran
    Translational Addiction Research Laboratory, Centre for Addiction and Mental Health, Toronto, ON, Canada
    Drug Alcohol Depend 123:190-200. 2012
    ..Cannabis is the most widely used illicit substance worldwide. The aim of the present study was to assess self-reported Quality of Life (QoL) among cannabis users in a large representative sample...
  56. ncbi Crack across Canada: Comparing crack users and crack non-users in a Canadian multi-city cohort of illicit opioid users
    Benedikt Fischer
    Centre for Addiction and Mental Health Univrersity of Toronto, Toronto, Ontario, Canada
    Addiction 101:1760-70. 2006
    ..To examine possible differences between crack users and crack non-users across Canada...
  57. ncbi How many people in Canada use prescription opioids non-medically in general and street drug using populations?
    Svetlana Popova
    Centre for Addiction and Mental Health, Toronto, ON, Canada
    Can J Public Health 100:104-8. 2009
    ..This study aimed to estimate the number of non-medical prescription opioid (PO) users in the general and street drug using populations in Canada...
  58. ncbi Safer injection facilities (SIFs) for injection drug users (IDUs) in Canada. A review and call for an evidence-focused pilot trial
    Benedikt Fischer
    Centre for Addiction and Mental Health, 33 Russell Street, Room 2036, Toronto, ON M5S 2S1
    Can J Public Health 93:336-8. 2002
  59. ncbi Alcohol-related morbidity and mortality
    Jurgen Rehm
    Addiction Research Institute, Zurich, Switzerland
    Alcohol Res Health 27:39-51. 2003
    ..Broad summary measures that reflect alcohol's possible effects on morbidity, mortality, and disability may be more useful than measures of any one outcome alone...
  60. ncbi Hepatitis C, illicit drug use and public health: does Canada really have a viable plan?
    Benedikt Fischer
    Centre for Addiction and Mental Health, Toronto, ON
    Can J Public Health 97:485-8. 2006
    ..In order to reduce the HCV disease burden, Canada needs to reconsider the scope, delivery and resourcing of both preventive and treatment interventions targeting the primary risk population of illicit drug users...
  61. ncbi Eyes wide shut?--A conceptual and empirical critique of methadone maintenance treatment
    Benedikt Fischer
    University of Toronto, Toronto, Canada
    Eur Addict Res 11:1-9; discussion 10-4. 2005
    ..Methadone maintenance treatment (MMT) has been the 'gold standard' pharmacotherapy treatment for illicit opioid dependence for over 30 years. It has been widely evaluated, and is generally claimed to be 'effective'...
  62. ncbi Moderate alcohol consumption and the gastrointestinal tract
    Benjamin Taylor
    Centre for Addiction and Mental Health, Toronto, Ont, Canada
    Dig Dis 23:170-6. 2005
    ..A high alcohol intake is significantly associated with diseases of the gastrointestinal tract, but less is known about the effects of moderate consumption, specifically moderate average volume of alcohol consumption...
  63. ncbi Heroin-assisted treatment as a response to the public health problem of opiate dependence
    Benedikt Fischer
    Department of Public Health Sciences, University of Toronto, McMurrich Bldg, 109C, Toronto, ON, M5S 1A8, Canada
    Eur J Public Health 12:228-34. 2002
    ....
  64. ncbi Bipolar disorder and co-occurring cannabis use disorders: characteristics, co-morbidities and clinical correlates
    Shaul Lev-Ran
    Social Aetiology of Mental Illness SAMI CIHR Training Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada Addictions Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada Electronic address
    Psychiatry Res 209:459-65. 2013
    ..Comprehensive evaluation of patients with bipolar disorder should include a systematic assessment of CUD. ..
  65. doi Selected pregnancy and delivery outcomes after exposure to antidepressant medication: a systematic review and meta-analysis
    Lori E Ross
    Social and Epidemiological Research Department, Centre for Addiction and Mental Health, University of Toronto, ON, Canada
    JAMA Psychiatry 70:436-43. 2013
    ..Untreated depression during pregnancy has been associated with increased morbidity and mortality for both mother and child and, as such, optimal treatment strategies are required for this population...
  66. doi Cannabis use and mental health-related quality of life among individuals with anxiety disorders
    Shaul Lev-Ran
    Social Aetiology of Mental Illness SAMI CIHR Training Program, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    J Anxiety Disord 26:799-810. 2012
    ..Out results highlight the importance of taking into account direct functional and emotional outcomes, as well as frequency of cannabis used, when assessing the impact of cannabis use among individuals with anxiety disorders...
  67. pmc Alcohol consumption and the risk of morbidity and mortality for different stroke types--a systematic review and meta-analysis
    Jayadeep Patra
    Centre for Addiction and Mental Health, Toronto, Ontario Canada
    BMC Public Health 10:258. 2010
    ..This meta-analysis is the first to explicitly separate morbidity and mortality of alcohol-attributable stroke and thus has implications for public health and prevention...
  68. ncbi Does price matter? The effect of decreased price on spirits consumption in Switzerland
    Meichun Kuo
    Addiction Research Institute, Zurich University, Switzerland
    Alcohol Clin Exp Res 27:720-5. 2003
    ....
  69. doi Cost of privatisation versus government alcohol retailing systems: Canadian example
    Svetlana Popova
    Public Health and Regulatory Policies, Centre for Addiction and Mental Health, Toronto, Canada
    Drug Alcohol Rev 31:4-12. 2012
    ..The aim of this study was to estimate the impact of the privatisation of alcohol sales on the burden and direct health-care, law enforcement costs and indirect costs (lost productivity due to disability or premature mortality) in Canada...
  70. pmc Heavy drinking occasions in relation to ischaemic heart disease mortality-- an 11-22 year follow-up of the 1984 and 1995 US National Alcohol Surveys
    Michael Roerecke
    Centre for Addiction and Mental Health, Toronto, ON, Canada
    Int J Epidemiol 40:1401-10. 2011
    ..The objective of this study was to investigate the association between heavy drinking occasions and IHD mortality while controlling for average daily alcohol intake and separating former drinkers from lifetime abstainers...
  71. doi Avoidable alcohol-attributable criminality and its costs due to selected interventions in Canada
    Jayadeep Patra
    Public Health and Regulatory Policies, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Int J Drug Policy 22:109-19. 2011
    ..Alcohol causes a considerable criminal burden on the Canadian society. The purpose of this study is to estimate the avoidable burden and avoidable costs of alcohol-attributable criminality in Canada for the year 2002...
  72. doi Alcohol and hypertension: gender differences in dose-response relationships determined through systematic review and meta-analysis
    Benjamin Taylor
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Addiction 104:1981-90. 2009
    ..To analyze the dose-response relationship between average daily alcohol consumption and the risk of hypertension via systematic review and meta-analysis...
  73. ncbi Public opinion towards supervised injection facilities and heroin-assisted treatment in Ontario, Canada
    Michelle Firestone Cruz
    Centre for Addiction and Mental Health, Toronto, Canada
    Int J Drug Policy 18:54-61. 2007
    ..Given the current political climate and the tentative position of SIFs and HAT in Canada, understanding the public's opinion is crucial for the feasibility and long-term sustainability of these interventions...
  74. doi Alcohol-attributable burden of disease and injury in Canada, 2004
    Kevin D Shield
    Centre for Addiction and Mental Health, 33 Russell Street, Toronto, ON, M5S 2S1, Canada
    Int J Public Health 57:391-401. 2012
    ..This analysis aimed to estimate the burden of disease and injury caused and prevented by alcohol in 2004 for Canadians aged 0-69 years and compare the effects of different magnitudes of adjustment of survey data on these estimates...
  75. ncbi The impact of tobacco tax cuts on smoking initiation among Canadian young adults
    Bo Zhang
    Ontario Tobacco Research Unit, Department of Public Health Sciences, University of Toronto, Toronto, Canada
    Am J Prev Med 30:474-9. 2006
    ..Using a longitudinal design, this study examined the impact of decreased cigarette price, resulting from tobacco tax cuts, on smoking initiation among Canadian young adults aged 20 to 24 years...
  76. ncbi Comparing injecting and non-injecting illicit opioid users in a multisite Canadian sample (OPICAN Cohort)
    Benedikt Fischer
    Centre for Addiction and Mental Health, University of Toronto, Toronto, Ontario, Canada
    Eur Addict Res 12:230-9. 2006
    ..Our results reinforce the need to explore potential interventions aimed at preventing the transition from non-injectors to injecting, or facilitating the transition of injectors to non-injecting, as initiated in several other contexts...
  77. ncbi Comparing alcohol consumption in central and eastern Europe to other European countries
    Svetlana Popova
    Social, Prevention and Health Policy Research Department, Centre for Addiction and Mental Heath, 33 Russell Street, Toronto, Ontario, Canada
    Alcohol Alcohol 42:465-73. 2007
    ....
  78. ncbi Prevalence of hepatitis and HIV infections and vaccination rates in patients entering the heroin-assisted treatment in Switzerland between 1994 and 2002
    Miriam Gerlich
    Research Institute for Public Health and Addiction, Konradstrasse 32, CH 8031, Zurich, Switzerland
    Eur J Epidemiol 21:545-9. 2006
    ..Hepatitis C virus (HCV) remains very prevalent in injection drug users (IDUs). In spite of recommended vaccinations against hepatitis A virus (HAV) and hepatitis B virus (HBV), many IDUs remain susceptible to HAV and HBV...
  79. doi Determination of lifetime injury mortality risk in Canada in 2002 by drinking amount per occasion and number of occasions
    Benjamin Taylor
    Centre for Addiction and Mental Health, 33 Russell Street, Toronto, Ontario, Canada
    Am J Epidemiol 168:1119-25; discussion 1126-31. 2008
    ..Absolute risk reflects long-term effects of drinking patterns and is important for risk-communication and alcohol-control policy...
  80. ncbi Smoking-attributable mortality and expected years of life lost in Canada 2002: conclusions for prevention and policy
    Dolly Baliunas
    Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Chronic Dis Can 27:154-62. 2007
    ..Cigarette smoking is a major contributor to mortality in Canada and its impact on Canadian society continues to be an unacceptable burden...
  81. ncbi Does the association between alcohol consumption and depression depend on how they are measured?
    Kathryn Graham
    Social Factors and Prevention Interventions Section, Centre for Addiction and Mental Health, University of Western Ontario, 100 Collip Circle, London, Ontario, Canada
    Alcohol Clin Exp Res 31:78-88. 2007
    ....
  82. ncbi Moderate alcohol consumption and diseases of the gastrointestinal system: a review of pathophysiological processes
    Benjamin Taylor
    Centre for Addiction and Mental Health, Toronto, Canada
    Dig Dis 23:177-80. 2005
    ..This review attempts to fill a gap in the literature surrounding moderate alcohol consumption...
  83. doi Causal considerations on alcohol and HIV/AIDS--a systematic review
    Paul A Shuper
    Centre for Addiction and Mental Health, 33 Russell Street, Room T 518, Toronto, Ontario, Canada M5S 2S1
    Alcohol Alcohol 45:159-66. 2010
    ..The study aimed to explore the possible causal nature of the association between alcohol consumption and HIV/AIDS...
  84. ncbi Volume of alcohol consumption, patterns of drinking and burden of disease in the European region 2002
    Jurgen Rehm
    Institut für Sucht und Gesundheitsforschung ISGF Research Institute for Public Health and Addictions, Zurich, Switzerland
    Addiction 101:1086-95. 2006
    ..To describe the volume of alcohol consumption and patterns of drinking in the World Health Organization (WHO) European regions in 2002 and to estimate quantitatively the burden of disease attributable to alcohol in that year...
  85. ncbi Evaluating long-term effects of heroin-assisted treatment: the results of a 6-year follow-up
    Franziska Güttinger
    Addiction Research Institute, Zurich, Switzerland
    Eur Addict Res 9:73-9. 2003
    ..Heroin-assisted treatment is thus efficacious in the long-term course of treatment and is still effective after termination of treatment with respect to living conditions and use of illicit substances...
  86. ncbi Global monitoring of average volume of alcohol consumption
    Jurgen Rehm
    Addiction Research Institute, Zurich
    Soz Praventivmed 47:48-58. 2002
    ..To check how the monitored indicator of average volume relates to prevalence of alcohol dependence. To discuss conclusions for establishing a global monitoring system...
  87. doi Anxiety and mood disorders and cannabis use
    Joyce T W Cheung
    Social, Prevention and Health Policy Research, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Am J Drug Alcohol Abuse 36:118-22. 2010
    ..Cannabis use has been linked to anxiety and mood disorders (AMD) in clinical cases, but little research on this relationship has been reported at the epidemiological level...
  88. doi Alcohol in Mayan Guatemala: consumption, distribution, production and composition of cuxa
    Fotis Kanteres
    Centre for Addiction and Mental Health, Toronto, ON, Canada
    Addiction 104:752-9. 2009
    ..Cuxa is a sugarcane-derived spirit, in part produced clandestinely, that has been distributed in the community for several decades...
  89. ncbi Problems with the graduated frequency approach to measuring alcohol consumption: results from a pilot study in Toronto, Canada
    Kathryn Graham
    Centre for Addiction and Mental Health, London, Ontario, Canada
    Alcohol Alcohol 39:455-62. 2004
    ..e. 12 or more drinks, at least eight drinks but less than 12, etc.)...
  90. ncbi A prospective cohort study on orally administered heroin substitution for severely addicted opioid users
    Ulrich Frick
    Research Institute for Addiction and Public Health, Zurich, Switzerland
    Addiction 101:1631-9. 2006
    ..To assess the efficacy and safety of orally administered heroin [diacetylmorphine (DAM)] tablets in substitution treatment of severely addicted opioid users...
  91. ncbi On the emerging paradigm of drinking patterns and their social and health consequences
    J Rehm
    Addiction Research Foundation, Toronto, Canada
    Addiction 91:1615-21. 1996
    ..In addition, we emphasize the need for improved methodologies and standardized methods for assessing drinking patterns. Finally, implications of research on drinking patterns for policy and programme development are discussed...
  92. pmc Dimensions underlying legislator support for tobacco control policies
    N A de Guia
    Ontario Tobacco Research Unit, Centre for Health Promotion, University of Toronto, Toronto, Ontario, Canada
    Tob Control 12:133-9. 2003
    ..To propose and test a new classification system for characterising legislator support for various tobacco control policies...
  93. ncbi Implications of privatizing/deregulating alcohol retail sales: projections of alcohol consumption in Ontario
    M Her
    Center for Addiction and Mental Health, Toronto, Ontario, Canada
    J Subst Abuse 10:355-73. 1998
    ..To project the consequences of privatizing or deregulating current alcohol retail monopolies in Ontario, Canada...
  94. ncbi Predictors of health risk behaviours among young adults: analysis of the National Population Health Survey
    K R Allison
    Department of Public Health Sciences, Faculty of Medicine, University of Toronto, Ontario
    Can J Public Health 90:85-9. 1999
    ..Thus, social context appears to be an important influence on risk-related behaviour, and should be taken into account in approaches designed to promote health behaviours...
  95. ncbi Aggregating dimensions of alcohol consumption to predict medical and social consequences
    J Rehm
    Addiction Research Foundation Division, Centre for Addictions and Mental Health CAMH, Toronto, Canada
    J Subst Abuse 12:155-68. 2000
    ..However, these relationships are not independent of each other and this multidimensionality is often mishandled or not taken into consideration at all in current alcohol epidemiology...
  96. pmc Avoidable portion of tobacco-attributable acute care hospital days and its cost due to implementation of different intervention strategies in Canada
    Svetlana Popova
    Public Health and Regulatory Policies, Centre for Addiction and Mental Health, Toronto, Canada
    Int J Environ Res Public Health 6:2179-92. 2009
    ..Although a sizable reduction in the number of hospital days and accumulated costs could be achieved, overall these interventions would reduce less than 3% of all tobacco-attributable costs in Canada...
  97. doi Social cost of heavy drinking and alcohol dependence in high-income countries
    Satya Mohapatra
    Centre for Addiction and Mental Health, Toronto, Canada
    Int J Public Health 55:149-57. 2010
    ..A comprehensive review of cost drivers associated with alcohol abuse, heavy drinking, and alcohol dependence for high-income countries was conducted...
  98. ncbi The economic costs of alcohol, tobacco and illicit drugs in Canada, 1992
    E Single
    Canadian Centre on Substance Abuse, University of Toronto, Ontario, Canada
    Addiction 93:991-1006. 1998
    ..AIMS, DESIGN AND SETTING: The economic costs of alcohol, tobacco and illicit drugs in Canadian society in 1992 are estimated utilizing a cost-of-illness framework and recently developed international guidelines...
  99. ncbi Alcohol and cardiovascular disease--more than one paradox to consider. Average volume of alcohol consumption, patterns of drinking and risk of coronary heart disease--a review
    J Rehm
    Addiction Research Institute, Zurich, Switzerland
    J Cardiovasc Risk 10:15-20. 2003
    ..Since patterns of drinking are important in determining CHD risk, they should be included in future epidemiologic studies, together with biomarkers further to test hypotheses about pathways...
  100. ncbi Aggregate time-series regression in the field of alcohol
    J Rehm
    Addiction Research Institute, Zurich, Switzerland
    Addiction 96:945-54. 2001
    ..This paper suggests minimal standards to conduct such analyses with respect to validity and reliability of underlying data, statistical techniques and requirements and interpretation of results...
  101. pmc Can legislation prevent debauchery? Mother gin and public health in 18th-century England
    J Warner
    Department of History, University of Toronto, Toronto, Ontario, Canada
    Am J Public Health 91:375-84. 2001
    ....