Determinants of villous trophoblastic hyperplasia in spontaneous abortionsR W Redline
Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA
Mod Pathol 11:762-8. 1998
..5 wk, P = .013), in those that lacked uniformly hydropic villi (P < .001), and in those that lacked fetal tissue (P = .204). This latter phenotype was particularly common with trisomies 15, 21, and 22...
- Placental lesions associated with cerebral palsy and neurologic impairment following term birth
R W Redline
Department of Pathology, Case Western University and University Hospitals of Cleveland, OH, USA
Arch Pathol Lab Med 124:1785-91. 2000
..The aim of this study was to determine the association of placental findings with cerebral palsy and related forms of neurologic impairment (NI) following birth at > or =37 weeks gestation (term)...
Differential expression of fibulin family proteins in the para-cervical weak zone and other areas of human fetal membranesR M Moore
Department of Pediatrics, Case Western Reserve University, Cleveland, OH, United States
Placenta 30:335-41. 2009
..A screen for differentially expressed proteins in the amnion of the weak zone versus other FM areas demonstrated that fibulin 1 was decreased. We investigated potential regional differences in all fibulin protein family members...
- Placental pathology: a systematic approach with clinical correlations
R W Redline
Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA
Placenta 29:S86-91. 2008
..Data are presented supporting the importance of these processes for an understanding of preterm delivery, intrauterine growth restriction, hypoxic-ischemic injury, and recurrent pregnancy loss...
- The physiology of fetal membrane rupture: insight gained from the determination of physical properties
R M Moore
Department of Pediatrics, MetroHealth Medical Center, Case Western Reserve University, Cleveland, OH, USA
Placenta 27:1037-51. 2006
..The ability to simultaneously correlate macroscopic physical properties with histological and biochemical fetal membrane characteristics, presents a unique perspective on the physiology of fetal membrane rupture...
- E-selectin expression and function in a unique placental trophoblast population at the fetal-maternal interface: regulation by a trophoblast-restricted transcriptional mechanism conserved between humans and mice
D S Milstone
Vascular Research Division, Department of Pathology, Brigham and Women s Hospital and Harvard Medical School, Boston, Massachusetts 02115, USA
Dev Dyn 219:63-76. 2000
..These results support the general hypothesis that endothelial-leukocyte adhesion molecules performing specialized functions in adults may also function in development of human and murine hemochorial placentae...
- Placental lesions associated with abnormal growth in twins
R W Redline
Department of Pathology, Case Western Reserve University School of Medicine and University Hospitals of Cleveland, OH 44106, USA
Pediatr Dev Pathol 4:473-81. 2001
..In summary, two placental lesions, peripheral cord insertion indicating a spatially limited intrauterine compartment and AV indicating occlusion of fetal vessels in the placenta, were associated with abnormal growth in twins...
- Cytologic features of intraabdominal desmoplastic small round cell tumor. A case report
I el-Kattan
Institute of Pathology, Case Western Reserve University, Cleveland, Ohio 44106, USA
Acta Cytol 39:514-20. 1995
..This karyotype differed from those in previous cases in that it lacked a 22q12-13 fusion partner but provided further evidence for involvement of the 11p13 region in the pathogenesis of this unusual tumor...
- Term human fetal membranes have a weak zone overlying the lower uterine pole and cervix before onset of labor
M El Khwad
Department of Pediatrics, MetroHealth Medical Center, Cleveland, OH 44109, USA
Biol Reprod 72:720-6. 2005
..A discrete zone of weakness is present in term prelabor FMs overlying the cervix and has biochemical characteristics consistent with tissue remodeling and apoptosis...
- Placental diagnostic criteria and clinical correlation--a workshop report
R W Redline
Department of Pathology, Case School of Medicine, Cleveland, OH 44106, USA
Placenta 26:S114-7. 2005
..This was followed by presentation of three studies correlating these pathologic processes with the following clinical outcomes: complications of prematurity, fetal growth restriction, and neurodisability following term delivery...
- Pulmonary immune responses during primary mycobacterium bovis- Calmette-Guerin bacillus infection in C57Bl/6 mice
S A Fulton
Division of Infectious Diseases and the Institute of Pathology, Case Western Reserve University and University Hospitals of Cleveland, Cleveland, Ohio 44106 4984, USA
Am J Respir Cell Mol Biol 22:333-43. 2000
..Tumor necrosis factor-alpha, IL-4 and IL-10 mRNA expression was not increased during M. bovis-BCG lung infection. Thus, protective immunity to M. bovis-BCG in the lung evolved differently in air space, lung, and lymph node...
- Differential expression of insulin-like growth factor-II in specific regions of the late (post day 9.5) murine placenta
R W Redline
Department of Pathology, Case Western Reserve University, Cleveland, OH 44106
Mol Reprod Dev 36:121-9. 1993
..Trophoblast lining the area of maternal-fetal exchange, the labyrinth, on the other hand, maintained a constitutive lower level of IGF-II expression throughout late pregnancy...
- Protective anti-Helicobacter immunity is induced with aluminum hydroxide or complete Freund's adjuvant by systemic immunization
J M Gottwein
Department of Pathology, Case Western Reserve University, Cleveland, Ohio, USA
J Infect Dis 184:308-14. 2001
..These results suggest an alternative and potentially more expeditious strategy for development of a human-use H. pylori vaccine...
