Kavita Reddy

Summary

Publications

  1. doi request reprint A systematic analysis of small supernumerary marker chromosomes using array CGH exposes unexpected complexity
    Kavita S Reddy
    Medical Genetics and Genomics Laboratory, Kaiser Permanente Southern California, Los Angeles, California, USA
    Genet Med 15:3-13. 2013
  2. doi request reprint Contemplations on preclinical validation of fluorescence in situ hybridization probe assay for paraffin-embedded tissues in hematologic disorders
    Kavita S Reddy
    Genzyme Genetics, New York 10019, USA
    Cancer Genet Cytogenet 183:1-5. 2008
  3. doi request reprint Blastic mantle cell lymphoma with a Burkitt translocation
    Kavita Reddy
    Genzyme Genetics, NY 10019, USA
    Leuk Lymphoma 49:740-50. 2008
  4. ncbi request reprint Double minutes (dmin) and homogeneously staining regions (hsr) in myeloid disorders: a new case suggesting that dmin form hsr in vivo
    K S Reddy
    Genzyme Genetics, New York, NY 10019, USA
    Cytogenet Genome Res 119:53-9. 2007
  5. ncbi request reprint Burkitt t(8;14)(q24;q32) and cryptic deletion in a CLL patient: report of a case and review of literature
    Kavita Reddy
    US Labs, 2601 Campus Drive, Irvine, CA 92612, USA
    Cancer Genet Cytogenet 166:12-21. 2006
  6. ncbi request reprint Chronic lymphocytic leukaemia profiled for prognosis using a fluorescence in situ hybridisation panel
    K S Reddy
    US Labs, Irvine, CA 92612, USA
    Br J Haematol 132:705-22. 2006
  7. doi request reprint Oligoarray (105K) CGH analysis of chromosome microdeletions within 10q22.1q24.32
    K S Reddy
    Genetics Department, Kaiser Permanente of Southern California, 4580 Electronics Place, Los Angeles, CA 90039, USA
    Cytogenet Genome Res 132:113-20. 2011
  8. pmc Cytogenetic abnormalities and fragile-X syndrome in Autism Spectrum Disorder
    Kavita S Reddy
    Genzyme Genetics, Orange CA 92868, USA
    BMC Med Genet 6:3. 2005
  9. doi request reprint The conundrum of a jumping translocation (JT) in CVS from twins and review of JTs
    Kavita S Reddy
    Kaiser Permanente Southern California, 4580 ElectronicPlace, Los Angeles, CA 90039, USA
    Am J Med Genet A 152:2924-36. 2010
  10. doi request reprint Assessment of 1p/19q deletions by fluorescence in situ hybridization in gliomas
    Kavita S Reddy
    Genzyme Genetics, 521 West 57th Street, New York, NY 10025, USA
    Cancer Genet Cytogenet 184:77-86. 2008

Detail Information

Publications16

  1. doi request reprint A systematic analysis of small supernumerary marker chromosomes using array CGH exposes unexpected complexity
    Kavita S Reddy
    Medical Genetics and Genomics Laboratory, Kaiser Permanente Southern California, Los Angeles, California, USA
    Genet Med 15:3-13. 2013
    ..In this study, a valid genotype-to-phenotype correlation was possible because the supernumerary marker chromosomes were fully characterized by array-based comparative genomic hybridization in a genome-wide analysis...
  2. doi request reprint Contemplations on preclinical validation of fluorescence in situ hybridization probe assay for paraffin-embedded tissues in hematologic disorders
    Kavita S Reddy
    Genzyme Genetics, New York 10019, USA
    Cancer Genet Cytogenet 183:1-5. 2008
    ..Although the procedure focuses on dual-color, dual-fusion FISH assays, the same steps could be used for any type of probe. We have described a preclinical validation for probes on paraffin-embedded tissue...
  3. doi request reprint Blastic mantle cell lymphoma with a Burkitt translocation
    Kavita Reddy
    Genzyme Genetics, NY 10019, USA
    Leuk Lymphoma 49:740-50. 2008
    ..The diagnosis was blastic MCL with Burkitt features. These cases, along with the reported cases, distinguish an aggressive category of a blastic MCL with a poor prognosis that probably requires Burkitt therapy...
  4. ncbi request reprint Double minutes (dmin) and homogeneously staining regions (hsr) in myeloid disorders: a new case suggesting that dmin form hsr in vivo
    K S Reddy
    Genzyme Genetics, New York, NY 10019, USA
    Cytogenet Genome Res 119:53-9. 2007
    ..Chronologically, the MYC-positive dmin appeared first, followed by the appearance of MYC-positive marker chromosomes, suggesting that the dmin may have evolved to form homogeneously staining regions (hsr) in vivo...
  5. ncbi request reprint Burkitt t(8;14)(q24;q32) and cryptic deletion in a CLL patient: report of a case and review of literature
    Kavita Reddy
    US Labs, 2601 Campus Drive, Irvine, CA 92612, USA
    Cancer Genet Cytogenet 166:12-21. 2006
    ....
  6. ncbi request reprint Chronic lymphocytic leukaemia profiled for prognosis using a fluorescence in situ hybridisation panel
    K S Reddy
    US Labs, Irvine, CA 92612, USA
    Br J Haematol 132:705-22. 2006
    ..The FISH panel could also serve to monitor 13q deletion for secondary changes with adverse prognosis. Understanding prognosis in specific types of 13q deletion would enhance outcome prediction...
  7. doi request reprint Oligoarray (105K) CGH analysis of chromosome microdeletions within 10q22.1q24.32
    K S Reddy
    Genetics Department, Kaiser Permanente of Southern California, 4580 Electronics Place, Los Angeles, CA 90039, USA
    Cytogenet Genome Res 132:113-20. 2011
    ..We have described the phenotype specific to the chromosome region involved within 10q22.1-q24.32. The oligoarray analysis improved the clinical management of the patients and enabled counseling for deleted genes...
  8. pmc Cytogenetic abnormalities and fragile-X syndrome in Autism Spectrum Disorder
    Kavita S Reddy
    Genzyme Genetics, Orange CA 92868, USA
    BMC Med Genet 6:3. 2005
    ..Ninety percent have idiopathic autism and a major gene has not yet been identified. We have assessed the incidence of chromosome abnormalities and Fragile X syndrome in a population of autistic patients referred to our laboratory...
  9. doi request reprint The conundrum of a jumping translocation (JT) in CVS from twins and review of JTs
    Kavita S Reddy
    Kaiser Permanente Southern California, 4580 ElectronicPlace, Los Angeles, CA 90039, USA
    Am J Med Genet A 152:2924-36. 2010
    ..This case illustrates the diagnostic challenges posed by JTs.In this study, our knowledge on JTs is consolidated to improve identification, management, and counseling...
  10. doi request reprint Assessment of 1p/19q deletions by fluorescence in situ hybridization in gliomas
    Kavita S Reddy
    Genzyme Genetics, 521 West 57th Street, New York, NY 10025, USA
    Cancer Genet Cytogenet 184:77-86. 2008
    ..Elucidated in this paper are the various FISH signal patterns observed in gliomas and a need for a uniform nomenclature for improved diagnosis...
  11. pmc Predicting adult metabolic syndrome from childhood body mass index: follow-up of the New Delhi birth cohort
    H P S Sachdev
    Department of Paediatrics, Sitaram Bhartia Institute of Science and Research, New Delhi, India
    Arch Dis Child 94:768-74. 2009
    ..To assess whether serial measurements of childhood body mass index (BMI) give clinically useful predictions of the risk of developing adult metabolic syndrome and impaired glucose tolerance or type 2 diabetes...
  12. ncbi request reprint Submicroscopic terminal deletion of 1p36.3 and Xp23 hidden in complex chromosome rearrangements: independent mechanism of telomere restitution on the two chromatids
    Kavita S Reddy
    Quest Diagnostics, Inc, San Juan Capistrano, California, USA
    Am J Med Genet A 117:261-7. 2003
    ..Our findings suggest that subtelomeric deletions should be ruled out in cases with complex and simple rearrangements involving the terminal regions...
  13. doi request reprint Two cases assessed for myeloid disorders had an unexpected twist
    Kavita S Reddy
    Cancer Genet Cytogenet 181:138-40. 2008
  14. ncbi request reprint Translocation (X;20)(q13;q13.3): a nonrandom abnormality in four patients with myeloid disorders
    Kavita S Reddy
    Genzyme Genetics, Orange, CA, USA
    Cancer Genet Cytogenet 157:70-3. 2005
    ..Previous FISH studies showed that the breakpoint on the X is proximal to XIST. In one of our cases, the breakpoint on the X was shown to be proximal to Xq12, by FISH using a probe for the androgen receptor gene locus...
  15. ncbi request reprint SKY assessment of two karyotypes with 0-6 supernumerary marker/ring chromosomes and review of previously reported cases with two or more markers
    Kavita S Reddy
    Department of Cytogenetics, Quest Diagnostics, Inc, San Juan Capistrano, California, USA
    Am J Med Genet A 118:156-71. 2003
    ..While two bisatellited markers may be associated with infertility, the phenotype in other cases ranged from borderline intelligence and mild dysmorphism to developmental delay, mental retardation, and congenital abnormalities...
  16. ncbi request reprint Prenatal management of mosaic tetrasomy 5p
    Kavita S Reddy
    Prenat Diagn 23:82-5. 2003