Cartilage-derived morphogenetic proteins and cartilage morphogenesisA H Reddi
Department of Orthopaedic Surgery, University of California Davis, School of Medicine, Sacramento 95817, USA
Microsc Res Tech 43:131-6. 1998
..Morphogens bind to extracellular matrix components and assemble a morphogenetic scaffold. Recent advances in CDMPs may aid in articular cartilage repair and regeneration...
Role of morphogenetic proteins in skeletal tissue engineering and regenerationA H Reddi
Center for Tissue Regeneration and Repair, University of California Davis, Medical Center, Sacramento 95817, USA
Nat Biotechnol 16:247-52. 1998
..Rules of tissue architecture elucidated in bone morphogenesis may provide insights into tissue engineering and be universally applicable for all organs/tissues, including bones and joints...
Interplay between bone morphogenetic proteins and cognate binding proteins in bone and cartilage development: noggin, chordin and DANA H Reddi
Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, University of California Davis, School of Medicine, Sacramento, California 95817, USA
Arthritis Res 3:1-5. 2001
..In addition, BMP actions may be potentiated by twisted gastrulation. BMPs and their binding proteins may play a critical role in regeneration of cartilage in osteoarthritis...
Microfracture and bone morphogenetic protein 7 (BMP-7) synergistically stimulate articular cartilage repairA C Kuo
The Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, University of California, Davis, 4635 Second Avenue, Room 2000, Sacramento, CA 95817, USA
Osteoarthritis Cartilage 14:1126-35. 2006
..We determined the effects of these two treatments alone and in combination on the quality and quantity of repair tissue formed in a model of full-thickness articular cartilage injury in adolescent rabbits...
Initiation and promotion of endochrondral bone formation by bone morphogenetic proteins: potential implications for avian tibial dyschondroplasiaA H Reddi
Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery University of California, Davis, Sacramento 95817, USA
Poult Sci 79:978-81. 2000
..Because there is a persistent defect in endochondral bone formation in the epiphysed growth plate in tibial dyschondroplasia in poultry, it is likely that BMP signaling mechanisms may be impaired...
Atomic force microscope investigation of the boundary-lubricant layer in articular cartilageS M T Chan
Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, University of California, Davis, Sacramento, CA 95817, USA
Osteoarthritis Cartilage 18:956-63. 2010
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Cartilage morphogenetic proteins: role in joint development, homoeostasis, and regenerationA H Reddi
Centre for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, University of California, Davis School of Medicine, Sacramento, California 95817, USA
Ann Rheum Dis 62:ii73-8. 2003
..Bone has the highest potential for regeneration. On the other hand, articular cartilage is recalcitrant to repair...
Effects of TGF-β1 on alternative splicing of Superficial Zone Protein in articular cartilage culturesG D Duraine
Lawrence Ellison Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, University of California Davis, School of Medicine, Sacramento, CA, United States
Osteoarthritis Cartilage 19:103-10. 2011
..The hypothesis of this study was that between load-bearing, and non-load-bearing locations, of the femoral medial condyle alternative splice isoforms of SZP are different, and regulated by TGF-β1...
Bone morphogenetic protein-7 selectively enhances mechanically induced bone formationA J Cheline
Orthopaedic Research Laboratory, Center for Tissue Regeneration and Repair, University of California at Davis Medical Center, Sacramento 95817, USA
Bone 31:570-4. 2002
..The higher BMP-7 dose more than doubled the load-induced increase in endosteal lamellar bone formation rate, primarily by increasing the amount of bone forming surface...
Bone morphogenetic proteins and skeletal development: the kidney-bone connectionA H Reddi
Center for Tissue Regeneration and Repair, Department of Orthopaedic Surgery, University of California, Davis, School of Medicine, Sacramento 95817, USA
Pediatr Nephrol 14:598-601. 2000
..In conclusion, we are beginning to unravel the mysteries of kidney-bone connection with special reference to pediatric nephrology...
Interleukin-17 family and IL-17 receptorsT A Moseley
Department of Orthopaedic Surgery, Center for Tissue Regeneration and Repair, School of Medicine, University of California, Davis, Sacramento, CA 95817, USA
Cytokine Growth Factor Rev 14:155-74. 2003
..This survey reviews the biological actions of IL-17 signaling in cancers, musculoskeletal tissues, the immune system and other tissues...
Cartilage morphogenesis: role of bone and cartilage morphogenetic proteins, homeobox genes and extracellular matrixA H Reddi
Department of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Matrix Biol 14:599-606. 1995
..An avalanche of recent advances from seemingly disparate areas bodes well for the complete elucidation of the molecular basis of morphogenesis of cartilage, the architectural blue-print for the skeleton...