Robert A Rebres

Summary

Publications

  1. pmc Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2
    Robert A Rebres
    Alliance for Cellular Signaling at Northern California Institute for Research and Education, VA Medical Center, San Francisco, California, USA
    J Leukoc Biol 87:1041-57. 2010
  2. pmc Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q
    Robert A Rebres
    Alliance for Cellular Signaling, Northern California Institute for Research and Education, University of California, Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Biol Chem 286:942-51. 2011
  3. pmc Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium
    Tamara I A Roach
    Alliance for Cellular Signaling, Northern California Institute for Research and Education, San Francisco, California 94121, USA
    J Biol Chem 283:17351-61. 2008
  4. pmc Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway
    Lily I Jiang
    Department of Pharmacology, Alliance for Cellular Signaling, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9196, USA
    J Biol Chem 282:10576-84. 2007
  5. ncbi request reprint Novel CD47-dependent intercellular adhesion modulates cell migration
    Robert A Rebres
    Program in Microbial Pathogenesis and Host Defense, University of California, San Francisco, California, USA
    J Cell Physiol 205:182-93. 2005

Detail Information

Publications5

  1. pmc Clostridium difficile toxin B differentially affects GPCR-stimulated Ca2+ responses in macrophages: independent roles for Rho and PLA2
    Robert A Rebres
    Alliance for Cellular Signaling at Northern California Institute for Research and Education, VA Medical Center, San Francisco, California, USA
    J Leukoc Biol 87:1041-57. 2010
    ..In sum, ToxB has opposing, independently regulated effects on Ca(2+) signaling by different GPCR-linked PLCbeta isoforms in macrophages...
  2. pmc Synergistic Ca2+ responses by G{alpha}i- and G{alpha}q-coupled G-protein-coupled receptors require a single PLC{beta} isoform that is sensitive to both G{beta}{gamma} and G{alpha}q
    Robert A Rebres
    Alliance for Cellular Signaling, Northern California Institute for Research and Education, University of California, Veterans Affairs Medical Center, San Francisco, California 94121, USA
    J Biol Chem 286:942-51. 2011
    ..We conclude that Ca(2+) synergy between Gα(i)-coupled and Gα(q)-coupled receptors requires the direct action of both Gβγ and Gα(q) on PLCβ and is mediated primarily by PLCβ3, although PLCβ2 is also competent...
  3. pmc Signaling and cross-talk by C5a and UDP in macrophages selectively use PLCbeta3 to regulate intracellular free calcium
    Tamara I A Roach
    Alliance for Cellular Signaling, Northern California Institute for Research and Education, San Francisco, California 94121, USA
    J Biol Chem 283:17351-61. 2008
    ..PLCbeta3 may thus provide a selective target for inhibiting Ca(2+) responses to mediators of inflammation, including C5a, UDP, PAF, and LPA...
  4. pmc Use of a cAMP BRET sensor to characterize a novel regulation of cAMP by the sphingosine 1-phosphate/G13 pathway
    Lily I Jiang
    Department of Pharmacology, Alliance for Cellular Signaling, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9196, USA
    J Biol Chem 282:10576-84. 2007
    ..Thus in these macrophage cells, all four major classes of G proteins can regulate intracellular cAMP...
  5. ncbi request reprint Novel CD47-dependent intercellular adhesion modulates cell migration
    Robert A Rebres
    Program in Microbial Pathogenesis and Host Defense, University of California, San Francisco, California, USA
    J Cell Physiol 205:182-93. 2005
    ..Thus, signaling dependent on both heterotrimeric and rho family GTPases can induce CD47 to participate in cell-cell interactions independent of known ligands that enhance intercellular adhesion and modulate cell migration...