Gerald Reaven

Summary

Publications

  1. ncbi request reprint Metabolic syndrome: pathophysiology and implications for management of cardiovascular disease
    Gerald Reaven
    Falk Cardiovascular Research Center, Stanford Medical Center, Stanford, Calif 94305, USA
    Circulation 106:286-8. 2002
  2. ncbi request reprint Prevalence of insulin resistance and associated cardiovascular disease risk factors among normal weight, overweight, and obese individuals
    Tracey McLaughlin
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Metabolism 53:495-9. 2004
  3. ncbi request reprint Heterogeneity in the prevalence of risk factors for cardiovascular disease and type 2 diabetes mellitus in obese individuals: effect of differences in insulin sensitivity
    Tracey McLaughlin
    Division of Endocrinology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Arch Intern Med 167:642-8. 2007
  4. ncbi request reprint Effects of moderate variations in macronutrient composition on weight loss and reduction in cardiovascular disease risk in obese, insulin-resistant adults
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Clin Nutr 84:813-21. 2006
  5. ncbi request reprint Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease?
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, California, USA
    Am J Cardiol 96:399-404. 2005
  6. ncbi request reprint Obesity, insulin resistance, and cardiovascular disease
    Gerald Reaven
    School of Medicine, Stanford University, Stanford, California 94305, USA
    Recent Prog Horm Res 59:207-23. 2004
  7. ncbi request reprint Use of metabolic markers to identify overweight individuals who are insulin resistant
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, California 94305, USA
    Ann Intern Med 139:802-9. 2003
  8. ncbi request reprint Comparative effects of rosuvastatin and gemfibrozil on glucose, insulin, and lipid metabolism in insulin-resistant, nondiabetic patients with combined dyslipidemia
    Cindy Lamendola
    Department of Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Am J Cardiol 95:189-93. 2005
  9. ncbi request reprint Clinical efficacy of two hypocaloric diets that vary in overweight patients with type 2 diabetes: comparison of moderate fat versus carbohydrate reductions
    Tracey McLaughlin
    Department of Endocrinology, Stanford University, 300 Pasteur Dr, Stanford, CA 94305 5103, USA
    Diabetes Care 30:1877-9. 2007
  10. ncbi request reprint Clinical experience with a relatively low carbohydrate, calorie-restricted diet improves insulin sensitivity and associated metabolic abnormalities in overweight, insulin resistant South Asian Indian women
    Andrea C Backes
    Department of Medicine, Stanford University Medical Center, Stanford, CA, USA
    Asia Pac J Clin Nutr 17:669-71. 2008

Collaborators

Detail Information

Publications25

  1. ncbi request reprint Metabolic syndrome: pathophysiology and implications for management of cardiovascular disease
    Gerald Reaven
    Falk Cardiovascular Research Center, Stanford Medical Center, Stanford, Calif 94305, USA
    Circulation 106:286-8. 2002
  2. ncbi request reprint Prevalence of insulin resistance and associated cardiovascular disease risk factors among normal weight, overweight, and obese individuals
    Tracey McLaughlin
    Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA
    Metabolism 53:495-9. 2004
    ..These results show that while BMI and insulin resistance are related, they are not synonymous, and that they make independent and different contributions to increasing CVD risk...
  3. ncbi request reprint Heterogeneity in the prevalence of risk factors for cardiovascular disease and type 2 diabetes mellitus in obese individuals: effect of differences in insulin sensitivity
    Tracey McLaughlin
    Division of Endocrinology, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Arch Intern Med 167:642-8. 2007
    ..We tested the hypothesis that risk factors for type 2 diabetes mellitus and cardiovascular disease vary dramatically in moderately obese individuals as a function of differences in a specific measure of insulin sensitivity...
  4. ncbi request reprint Effects of moderate variations in macronutrient composition on weight loss and reduction in cardiovascular disease risk in obese, insulin-resistant adults
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, CA 94305, USA
    Am J Clin Nutr 84:813-21. 2006
    ..Obese, insulin-resistant persons are at risk of cardiovascular disease. How best to achieve both weight loss and clinical benefit in these persons is controversial, and recent reports questioned the superiority of low-fat diets...
  5. ncbi request reprint Is there a simple way to identify insulin-resistant individuals at increased risk of cardiovascular disease?
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, California, USA
    Am J Cardiol 96:399-404. 2005
    ..5 provides a simple means of identifying insulin-resistant, dyslipidemic patients who are likely to be at increased risk of cardiovascular disease...
  6. ncbi request reprint Obesity, insulin resistance, and cardiovascular disease
    Gerald Reaven
    School of Medicine, Stanford University, Stanford, California 94305, USA
    Recent Prog Horm Res 59:207-23. 2004
    ....
  7. ncbi request reprint Use of metabolic markers to identify overweight individuals who are insulin resistant
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, California 94305, USA
    Ann Intern Med 139:802-9. 2003
    ....
  8. ncbi request reprint Comparative effects of rosuvastatin and gemfibrozil on glucose, insulin, and lipid metabolism in insulin-resistant, nondiabetic patients with combined dyslipidemia
    Cindy Lamendola
    Department of Medicine, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    Am J Cardiol 95:189-93. 2005
    ..05) in rosuvastatin-treated patients, and this difference in the relative effectiveness of the drugs was also true of the decrease in non-high-density lipoprotein cholesterol concentrations...
  9. ncbi request reprint Clinical efficacy of two hypocaloric diets that vary in overweight patients with type 2 diabetes: comparison of moderate fat versus carbohydrate reductions
    Tracey McLaughlin
    Department of Endocrinology, Stanford University, 300 Pasteur Dr, Stanford, CA 94305 5103, USA
    Diabetes Care 30:1877-9. 2007
  10. ncbi request reprint Clinical experience with a relatively low carbohydrate, calorie-restricted diet improves insulin sensitivity and associated metabolic abnormalities in overweight, insulin resistant South Asian Indian women
    Andrea C Backes
    Department of Medicine, Stanford University Medical Center, Stanford, CA, USA
    Asia Pac J Clin Nutr 17:669-71. 2008
    ....
  11. ncbi request reprint All obese individuals are not created equal: insulin resistance is the major determinant of cardiovascular disease in overweight/obese individuals
    Gerald Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, California 94305, USA
    Diab Vasc Dis Res 2:105-12. 2005
    ....
  12. doi request reprint Use of a two-stage insulin infusion study to assess the relationship between insulin suppression of lipolysis and insulin-mediated glucose uptake in overweight/obese, nondiabetic women
    Tracey McLaughlin
    Stanford University School of Medicine, Division of Endocrinology, Stanford, CA 94305 5103, USA
    Metabolism 60:1741-7. 2011
    ..Both can be quantified using a simple 2-stage insulin infusion study, with first-stage FFA concentrations and second-stage glucose concentrations being most informative...
  13. doi request reprint Insulin resistance and coronary heart disease in nondiabetic individuals
    Gerald Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Falk CVRC Stanford Medical Center, 300 Pasteur Dr, Stanford, CA 94306, USA
    Arterioscler Thromb Vasc Biol 32:1754-9. 2012
    ..Resistance to insulin-mediated glucose disposal and hyperinsulinemia is a common finding in apparently healthy individuals and is associated with a number of abnormalities that greatly increase risk of CHD...
  14. pmc Differential effects of insulin sensitivity on androgens in obese women with polycystic ovary syndrome or normal ovulation
    Tomoko Asagami
    Falk Cardiovascular Research Center, Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305 5406, USA
    Metabolism 57:1355-60. 2008
    ..In contrast, androstenedione concentrations seem to be independent of differences in insulin resistance. Our findings emphasize the need to increase understanding of the factors that modulate ovarian androgen secretion...
  15. doi request reprint Why a cluster is truly a cluster: insulin resistance and cardiovascular disease
    Gerald Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford Medical Center, Falk CVRC, Stanford, CA 94305, USA
    Clin Chem 54:785-7. 2008
  16. ncbi request reprint Usefulness of plasma glucose and insulin concentrations in identifying patients with insulin resistance
    Cheng Yang Tuan
    Stanford University School of Medicine, Stanford, California 94305, USA
    Am J Cardiol 92:606-10. 2003
    ..We then made standard measurements of plasma glucose and insulin concentrations to see how useful they would be as surrogate markers of insulin resistance...
  17. ncbi request reprint The metabolic syndrome or the insulin resistance syndrome? Different names, different concepts, and different goals
    Gerald Reaven
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Falk CVRC, 300 Pasteur Drive, Stanford, CA 94305, USA
    Endocrinol Metab Clin North Am 33:283-303. 2004
    ....
  18. ncbi request reprint Counterpoint: just being alive is not good enough
    Gerald Reaven
    Division of Cardiovascular Medicine, Falk CVRC, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA 94305, USA
    Clin Chem 51:1354-7. 2005
  19. ncbi request reprint Insulin resistance, hypertension, and coronary heart disease
    Gerald Reaven
    Stanford University School of Medicine, Stanford Medical Center, 300 Pasteur Drive, Stanford, CA 94305 5406, USA
    J Clin Hypertens (Greenwich) 5:269-74. 2003
    ..Although it remains a scientific issue of great importance, the scope of this review precludes a discussion of the mechanistic link between insulin resistance/hyperinsulinemia and essential hypertension...
  20. ncbi request reprint Insulin resistance and compensatory hyperinsulinemia: the key player between cigarette smoking and cardiovascular disease?
    Gerald Reaven
    Division of Cardiovascular Medicine, Falk CVRC, Stanford University School of Medicine, 300 Pasteur Drive, Stanford, CA 94305, USA
    J Am Coll Cardiol 41:1044-7. 2003
    ..As a corollary, it is suggested that CVD risk in individuals who cannot, or will not, stop smoking can be reduced by therapeutic efforts aimed at attenuating the adverse effects of insulin resistance and its consequences...
  21. ncbi request reprint Type 2 diabetes and coronary heart disease: we keep learning how little we know
    Gerald Reaven
    Arterioscler Thromb Vasc Biol 23:917-8. 2003
  22. ncbi request reprint Whole-body glycolysis measured by the deuterated-glucose disposal test correlates highly with insulin resistance in vivo
    Carine Beysen
    KineMed, Inc, Emeryville, California, USA
    Diabetes Care 30:1143-9. 2007
    ....
  23. ncbi request reprint Insulin resistance, type 2 diabetes mellitus, and cardiovascular disease: the end of the beginning
    Gerald Reaven
    Circulation 112:3030-2. 2005
  24. ncbi request reprint Differentiation between obesity and insulin resistance in the association with C-reactive protein
    Tracey McLaughlin
    Stanford University School of Medicine, Stanford, Calif, USA
    Circulation 106:2908-12. 2002
    ..Plasma C-reactive protein (CRP) concentrations are increased in obese and/or hyperinsulinemic individuals. The goal of this study was to determine if the relation between insulin resistance and CRP was independent of obesity...
  25. ncbi request reprint Do coronary heart disease risk factors change over time?
    Ivana Zavaroni
    Dipartimento di Medicina Interna e Scienze Biomediche Universit√° di Parma, Parma, Italy
    Metabolism 51:1022-6. 2002
    ..These results demonstrate that the implicit assumption in epidemiological studies that CHD risk factors at baseline remain stable may require examination...