Jean Raymond

Summary

Publications

  1. ncbi Temporary vascular occlusion with poloxamer 407
    Jean Raymond
    Interventional Neuroradiology Laboratory, CHUM Research Center, Notre Dame Hospital, Mailloux Pavilion M 8206, 1560 Sherbrooke East, Montreal, Que, Canada H2L 4M1
    Biomaterials 25:3983-9. 2004
  2. pmc A Randomized Trial Comparing Platinum and Hydrogel-coated Coils in Patients Prone to Recurrence after Endovascular Treatment (The PRET Trial)
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Universite de Montreal, CHUM Notre Dame Hospital, Montreal Canada
    Interv Neuroradiol 14:73-83. 2008
  3. pmc Unruptured Intracranial Aneurysms. A Critical Review of the International Study of Unruptured Intracranial Aneurysms (ISUIA) and of Appropriate Methods to Address the Clinical Problem
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Universite de Montreal, CHUM Notre Dame Hospital, Montreal Canada
    Interv Neuroradiol 14:85-96. 2008
  4. pmc The prevention of hemorrhagic stroke. A review of the rational and ethical principles of clinical trials on unruptured intracranial aneurysms and arteriovenous malformations
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Canada
    Interv Neuroradiol 14:365-73. 2008
  5. ncbi Beta radiation and inhibition of recanalization after coil embolization of canine arteries and experimental aneurysms: how should radiation be delivered?
    Jean Raymond
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Hopital Notre Dame, Montreal, Quebec, Canada H2L 4M1
    Stroke 34:1262-8. 2003
  6. ncbi The practice of ethics in the era of evidence-based radiology
    Jean Raymond
    Department of Radiology, Interventional Neuroradiology Section, Centre Hospitalier de l Universite de Montreal, Notre Dame and St Luc Hospitals, 1560 Sherbrooke East, Suite M8206, Montreal, QC, Canada, H2L 4M1
    Radiology 244:643-9. 2007
  7. ncbi Interventional neuroradiology: the role of experimental models in scientific progress
    J Raymond
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Canada
    AJNR Am J Neuroradiol 28:401-5. 2007
  8. ncbi Endoluminal cryotherapy to prevent recanalization after endovascular occlusion with platinum coils
    Jean Raymond
    Research Centre, Radiology Department, Centre Hospitalier de l Université de Montréal Notre Dame Hospital, 1560 Sherbrooke East, suite M 8203, Montreal, Quebec, Canada H2L 4M1
    J Vasc Interv Radiol 17:1499-504. 2006
  9. pmc Unruptured Intracranial Aneurysms. Opinions of Experts in Endovascular Treatment Are Coherent,Weighted in Favour of Treatment, and Incompatible with ISUIA
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Centre hospitalier de l Universite de Montreal CHUM Notre Dame Hospital, Montreal, Canada
    Interv Neuroradiol 13:225-37. 2007
  10. ncbi Unruptured intracranial aneurysms: the unreliability of clinical judgment, the necessity for evidence, and reasons to participate in a randomized trial
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Universite de Montreal, CHUM Notre Dame Hospital, Montreal, Canada
    J Neuroradiol 33:211-9. 2006

Collaborators

Detail Information

Publications84

  1. ncbi Temporary vascular occlusion with poloxamer 407
    Jean Raymond
    Interventional Neuroradiology Laboratory, CHUM Research Center, Notre Dame Hospital, Mailloux Pavilion M 8206, 1560 Sherbrooke East, Montreal, Que, Canada H2L 4M1
    Biomaterials 25:3983-9. 2004
    ..The only biochemical effect of poloxamer occlusions was transient elevation of triglyceride levels. There were no pathological abnormalities at 1 week. Poloxamer 407 could be used as an embolic material for temporary occlusions...
  2. pmc A Randomized Trial Comparing Platinum and Hydrogel-coated Coils in Patients Prone to Recurrence after Endovascular Treatment (The PRET Trial)
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Universite de Montreal, CHUM Notre Dame Hospital, Montreal Canada
    Interv Neuroradiol 14:73-83. 2008
    ..The recurrence problem may be more pressing in certain types of patients, such as patients with large aneurysms or those already presenting with angiographic recurrences...
  3. pmc Unruptured Intracranial Aneurysms. A Critical Review of the International Study of Unruptured Intracranial Aneurysms (ISUIA) and of Appropriate Methods to Address the Clinical Problem
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Universite de Montreal, CHUM Notre Dame Hospital, Montreal Canada
    Interv Neuroradiol 14:85-96. 2008
    ..A randomized trial is in order to clarify what is the role of prevention in this common clinical problem...
  4. pmc The prevention of hemorrhagic stroke. A review of the rational and ethical principles of clinical trials on unruptured intracranial aneurysms and arteriovenous malformations
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Canada
    Interv Neuroradiol 14:365-73. 2008
    ..Some tension exists between scientific methods and normal practice, but they need to coexist if we are to progress at the same time we care for patients...
  5. ncbi Beta radiation and inhibition of recanalization after coil embolization of canine arteries and experimental aneurysms: how should radiation be delivered?
    Jean Raymond
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Hopital Notre Dame, Montreal, Quebec, Canada H2L 4M1
    Stroke 34:1262-8. 2003
    ..Beta radiation prevents recanalization after coil embolization. We sought to determine the effects of varying coil caliber, length, activity of 32P per centimeter of coil or per volume, and spatial distribution of coils on recanalization...
  6. ncbi The practice of ethics in the era of evidence-based radiology
    Jean Raymond
    Department of Radiology, Interventional Neuroradiology Section, Centre Hospitalier de l Universite de Montreal, Notre Dame and St Luc Hospitals, 1560 Sherbrooke East, Suite M8206, Montreal, QC, Canada, H2L 4M1
    Radiology 244:643-9. 2007
    ..The result is a stronger moral personal identity and a brighter horizon for a satisfying professional life...
  7. ncbi Interventional neuroradiology: the role of experimental models in scientific progress
    J Raymond
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Canada
    AJNR Am J Neuroradiol 28:401-5. 2007
    ..Each step is essential and the sequence cannot be violated without risks of errors that eventually translate into clinical morbidity...
  8. ncbi Endoluminal cryotherapy to prevent recanalization after endovascular occlusion with platinum coils
    Jean Raymond
    Research Centre, Radiology Department, Centre Hospitalier de l Université de Montréal Notre Dame Hospital, 1560 Sherbrooke East, suite M 8203, Montreal, Quebec, Canada H2L 4M1
    J Vasc Interv Radiol 17:1499-504. 2006
    ..Endovascular embolization with platinum coils is sometimes followed by recanalization. The present study was undertaken to assess whether cryoablation of the endothelial lining could prevent recanalization after coil occlusion...
  9. pmc Unruptured Intracranial Aneurysms. Opinions of Experts in Endovascular Treatment Are Coherent,Weighted in Favour of Treatment, and Incompatible with ISUIA
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Centre hospitalier de l Universite de Montreal CHUM Notre Dame Hospital, Montreal, Canada
    Interv Neuroradiol 13:225-37. 2007
    ..Only data from a randomized trial could provide convincing objective evidence in favour or against preventive treatment of unruptured intracranial aneurysms...
  10. ncbi Unruptured intracranial aneurysms: the unreliability of clinical judgment, the necessity for evidence, and reasons to participate in a randomized trial
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Universite de Montreal, CHUM Notre Dame Hospital, Montreal, Canada
    J Neuroradiol 33:211-9. 2006
  11. ncbi Follow-up of treated aneurysms: the challenge of recurrences and potential solutions
    Jean Raymond
    Department of Radiology, Radio Oncology and Nuclear Medicine, Faculty of Medicine, Universite de Montreal, Pavilion Roger Gaudry, 2900 Boulevard Edouard Montpetit, Montreal, Quebec, Canada H3T 1J4
    Neuroimaging Clin N Am 16:513-23, ix. 2006
    ..None of the recent devices has been proven effective in improving long-term results. A rigorous scientific approach, including randomized trials, is imperative to forward progress in this field...
  12. pmc A randomized trial on the safety and efficacy of endovascular treatment of unruptured intracranial aneurysms is feasible
    J Raymond
    CHUM Notre Dame Hospital, Radiology Department, Université de Montréal Montréal, Quebec, Canada
    Interv Neuroradiol 10:103-12. 2004
    ..A randomized trial comparing endovascular and conservative treatment could have an important impact on the clinical management of intracranial aneurysms...
  13. ncbi Safety and effectiveness of radioactive coil embolization of aneurysms: effects of radiation on recanalization, clot organization, neointima formation, and surrounding nerves in experimental models
    Jean Raymond
    Centre Hospitalier de l Université de Montréal Hôpital Notre Dame, Interventional Neuroradiology Research Laboratory, 1560 Sherbrooke E, suite M 8203, Montreal, Quebec, Canada H2L 4M1
    Stroke 37:2147-52. 2006
    ..We wanted to determine the upper limits of 32P activities that could be implanted onto coils with respect to the potential injury to nearby nerves, delay in organization of the clot, and effects on neointima formation and recanalization...
  14. pmc New Devices Designed to Improve the Long-Term Results of Endovascular Treatment of Intracranial Aneurysms. A Proposition for a Randomized Clinical Trial to Assess their Safety and Efficacy
    J Raymond
    Department of Radiology, Research center of Centre hospitalier de l Université de Montréal CHUM Notre Dame hospital Montréal, Quebec, Canada
    Interv Neuroradiol 10:93-102. 2004
    ..The scientific demonstration of an improved long-term efficacy, without significant compromise regarding safety, is mandatory before considering the widespread use of a new embolic device for the endovascular treatment of aneurysms...
  15. ncbi Endovascular treatment of aneurysms: gene expression of neointimal cells recruited on the embolic agent and evolution with recurrence in an experimental model
    Jean Raymond
    CHUM Research Centre Notre Dame Hospital, Montreal, Quebec, Canada
    J Vasc Interv Radiol 16:1355-63. 2005
    ..A better understanding of the relationship between blood flow, molecular events, and healing or recurrence may provide future avenues to improve results of endovascular treatment of aneurysms...
  16. ncbi Endovascular treatment of intracranial aneurysms with radioactive coils: initial clinical experience
    Jean Raymond
    Department of Radiology, Centre hospitalier de l Universite de Montreal CHUM Notre Dame Hospital, Montreal, Quebec, Canada
    Stroke 34:2801-6. 2003
    ..Beta radiation prevents recanalization after coil embolization in experimental models. We wanted to assess the feasibility of using radioactive coil embolization to improve long-term results of endovascular treatment...
  17. doi Mechanisms of occlusion and recanalization in canine carotid bifurcation aneurysms embolized with platinum coils: an alternative concept
    J Raymond
    Interventional Neuroradiology Laboratory, CHUM Research Centre, Centre Hospitalier de l Université de Montréal Hôpital Notre Dame, Quebec, Canada
    AJNR Am J Neuroradiol 29:745-52. 2008
    ..The goal of the present study was to better define pathologic features associated with so-called healing or recurrences after coiling and to propose an alternative concept to the currently accepted view...
  18. ncbi [Science and ethics, therapeutic misconception and mirage]
    J Raymond
    Departement de Radiologie, Centre Hospitalier de l Universite de Montreal CHUM, 1560, Sherbrooke Est, Pavillon Simard, suite Z12909, Montreal, Quebec, Canada H2L 4M1
    J Neuroradiol 35:268-72. 2008
    ..Not only should clinical research be integrated to the good practice of medicine, it should also be part of training in our specialty...
  19. ncbi Role of the endothelial lining in persistence of residual lesions and growth of recurrences after endovascular treatment of experimental aneurysms
    Jean Raymond
    Department of Radiology, Centre Hospitalier de l Université de Montréal Hôpital Notre Dame, Montreal, Quebec, Canada
    Stroke 33:850-5. 2002
    ..We sought to investigate the role of the endothelial lining in aneurysmal persistence and recurrence after endovascular treatment of aneurysms...
  20. doi Radiofrequency endothelial ablation prevents recanalization after endovascular coil occlusion: in vitro and in vivo assessment
    Jean Raymond
    Interventional Neuroradiology Research Laboratory, Research Center, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, 1560 Sherbrooke East Pavillon Simard, Ste Z12909, Montreal, Quebec, Canada
    J Vasc Interv Radiol 21:101-7. 2010
    ..Coil embolization of intracranial aneurysms may be followed by recurrences. Radiofrequency (RF) ablation of the endothelium may prevent recanalization after coil embolization...
  21. ncbi Incidental intracranial aneurysms: rationale for treatment
    Jean Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Canada
    Curr Opin Neurol 22:96-102. 2009
    ..The review critically appraises the available evidence and current rationale for treating incidental intracranial aneurysms...
  22. ncbi In situ beta radiation to prevent recanalization after coil embolization of cerebral aneurysms
    Jean Raymond
    Department of Radiology, University of Montreal, University of Montreal Medical Center, Notre Dame Hospital, Quebec, Canada
    Stroke 33:421-7. 2002
    ..The purpose of this work was to assess if in situ beta radiation can inhibit recanalization after coil embolization...
  23. ncbi Feasibility of radioactive embolization of intracranial aneurysms using 32P-implanted coils
    Jean Raymond
    Department of Radiology, Research Centre of Centre Hospitalier de l Université de Montréal, Quebec, Canada
    Stroke 34:1035-7. 2003
    ..Beta radiation can prevent recanalization after embolization. Our goal was to assess the feasibility of endovascular treatment of intracranial aneurysms using coils of a predetermined activity of 32P per centimeter...
  24. doi Unruptured intracranial aneurysms: their illusive natural history and why subgroup statistics cannot provide normative criteria for clinical decisions or selection criteria for a randomized trial
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Universite de Montreal, CHUM Notre Dame Hospital, 1560, Sherbrooke East, suite Z12909, H2L 4M1 Montréal, Quebec, Canada
    J Neuroradiol 35:210-6. 2008
    ....
  25. ncbi Long-term angiographic recurrences after selective endovascular treatment of aneurysms with detachable coils
    Jean Raymond
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, 1560 Sherbrooke East, Room M 8203 1, Montreal, Quebec, H2L 4M1, Canada
    Stroke 34:1398-403. 2003
    ..Our aim in this study was to assess the incidence and determining factors of angiographic recurrences after endovascular treatment of aneurysms...
  26. pmc ICONE: An International Consortium of Neuro Endovascular Centres
    J Raymond
    Interventional Neuroradiology Research Unit, Department of Radiology, Universite de Montreal, CHUM Notre Dame Hospital, Montreal, Canada
    Interv Neuroradiol 14:203-8. 2008
    ..The Consortium is a realistic endeavour optimally structured to promote excellence through scientific appraisal of our treatments, and to accelerate technical progress while maximizing patients' safety and welfare...
  27. ncbi Endovascular treatment of experimental wide neck aneurysms: comparison of results using coils or cyanoacrylate with the assistance of an aneurysm neck bridge device
    Jean Raymond
    Centre de Recherche, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    AJNR Am J Neuroradiol 23:1710-6. 2002
    ..The two goals of the present study were to compare results of coil embolization with or without the assistance of an aneurysm neck bridge device (ANBD) and to explore the use of this instrument to control cyanoacrylate embolization...
  28. ncbi The effects of stenting and endothelial denudation on aneurysm and branch occlusion in experimental aneurysm models
    Tim Darsaut
    CHUM Notre Dame Hospital, Montreal, Quebec, Canada
    J Vasc Surg 45:1228-35. 2007
    ..Stents are increasingly used in the endovascular treatment of intracranial aneurysms. We studied the effects of stenting and endothelial denudation on aneurysm and branch vessel occlusion...
  29. doi Role of the endothelial lining in endoleak formation and persistence after endovascular repair of aneurysm
    Gilles Soulez
    Department of Radiology, University of Montreal and CHUM Notre Dame, 1560 Sherbrooke East, Montreal, Quebec, Canada
    J Vasc Interv Radiol 19:1070-8. 2008
    ..To evaluate whether ablation of the endothelial lining of an aneurysm can prevent endoleak persistence after endovascular aneurysm repair (EVAR)...
  30. ncbi Alginate for endovascular treatment of aneurysms and local growth factor delivery
    Jean Raymond
    Interventional Neuroradiology Laboratory, CHUM Research Center, Notre Dame Hospital, 1560 Sherbrooke East, suite M 8203, Montreal, Quebec, Canada H2L 4M1
    AJNR Am J Neuroradiol 24:1214-21. 2003
    ..Our purpose was to explore the use of alginate as a new embolic agent that could deliver growth factors and improve results of endovascular treatment of aneurysms...
  31. ncbi Matrix metalloproteinase-9 may play a role in recanalization and recurrence after therapeutic embolization of aneurysms or arteries
    Fatiha Bouzeghrane
    Interventional Neuroradiology Research Laboratory, Centre Hospitalier de L Universite de Montreal Research Center, Notre Dame Hospital, Montreal, Quebec
    J Vasc Interv Radiol 18:1271-9. 2007
    ..Matrix metalloproteinase (MMP)-9 plays various roles in vascular healing and angiogenesis. This study was conducted to determine if MMP-9 is involved in healing or recanalization after therapeutic occlusion of arteries or aneurysms...
  32. ncbi Lingual artery bifurcation aneurysms for training and evaluation of neurovascular devices
    Jean Raymond
    Interventional Neuroradiology Laboratory, CHUM Research Center, Notre Dame Hospital, Montreal, Quebec, Canada
    AJNR Am J Neuroradiol 25:1387-90. 2004
    ..We conclude that this model may be useful for training in endovascular techniques, but because of the lack of sufficient aneurysmal recurrence, it is not suitable for evaluating new embolic agents...
  33. ncbi Type I and collateral flow in experimental aneurysm models treated with stent-grafts
    Gilles Soulez
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Quebec, H2L 4M1, Canada
    J Vasc Interv Radiol 18:265-72. 2007
    ..To evaluate the influence of a collateral branch on the evolution of type I leaks after endovascular aneurysm repair in an experimental model...
  34. ncbi High-concentration ethylene-vinyl alcohol copolymer and endovascular treatment of experimental aneurysms: feasibility of embolization without protection devices at the neck
    Jean Raymond
    Department of Radiology, Centre Hospitalier de l Universite de Montreal CHUM, Notre Dame Hospital, Montreal, Quebec, Canada
    AJNR Am J Neuroradiol 24:1778-84. 2003
    ..The purpose of this study was to assess the feasibility of endovascular treatment of aneurysms with high-concentration ethylene-vinyl alcohol copolymer (HCEVOH), without the use of protection devices at the neck...
  35. ncbi Role of the endothelial lining in recurrences after coil embolization: prevention of recanalization by endothelial denudation
    Jean Raymond
    Radiology Department, CHUM Notre Dame Hospital, Interventional Neuroradiology Laboratory, 1560 Sherbrooke East, suite M 8203, Montreal, Quebec, Canada
    Stroke 35:1471-5. 2004
    ..Endothelial denudation before coil embolization may prevent recanalization and improve results of endovascular treatment...
  36. ncbi In situ beta-irradiation of a brain arteriovenous malformation model
    Daniel Roy
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital Research Centre, Montreal, Quebec, Canada
    Stroke 36:2475-8. 2005
    ..The study goal is to enhance the efficacy of arteriovenous malformation embolization by adding a beta-emitting isotope to the embolic agent...
  37. ncbi Surgical construction of an in vivo carotid siphon model to test neurovascular devices
    Stavros A Georganos
    Department of Radiology, Notre Dame Hospital, Montreal, Quebec, Canada
    Neurosurgery 54:1239-43; discussion 1243. 2004
    ..We developed an animal model to evaluate vascular trauma induced by endovascular devices that are proposed for the treatment of cerebrovascular diseases...
  38. ncbi Postcoiling aneurysm tilting: a disturbing finding?
    Eric Sauvageau
    Department of Neuroradiology, Centre Hospitalier Universitaire de Montreal, Quebec, Canada
    AJNR Am J Neuroradiol 25:601-3. 2004
    ..We present two patients with posterior tilting of a basilar tip aneurysm after selective coiling. The cause and significance of this finding are discussed...
  39. doi Endothelial denudation combined with embolization in the prevention of endoleaks after endovascular aneurysm repair: an animal study
    Sophie Lerouge
    Research Centre, Centre hospitalier de l Université de Montréal CRCHUM, Montreal, QC, Canada
    J Endovasc Ther 18:686-96. 2011
    ..To test whether combining embolization with endothelial denudation could reduce endoleak persistence and recurrence after endovascular aneurysm repair (EVAR) in an animal model...
  40. ncbi Production of radioactive particles for endovascular therapeutic interventions
    Jean Raymond
    CHUM Notre Dame Hospital, 1560 Sherbrooke East, Montreal, Que, Canada H2L 4M1
    Biomaterials 27:1566-72. 2006
    ..Both radioactive microspheres (198Au and 32P) showed no detectable activity outside the target territory. 32P microspheres demonstrated typical radiation changes in a porcine rete mirabile arteriovenous malformation model...
  41. ncbi Recanalization of arterial thrombus, and inhibition with beta-radiation in a new murine carotid occlusion model: MRNA expression of angiopoietins, metalloproteinases, and their inhibitors
    Jean Raymond
    CHUM Research Centre, Notre Dame Hospital, Montreal, Quebec, Canada
    J Vasc Surg 40:1190-8. 2004
    ..We attempted to characterize molecular events related to recanalization or organization of arterial thrombus in a new murine model by studying genes reported to be involved in angiogenesis or neointima formation...
  42. ncbi Cyanoacrylate embolization of experimental aneurysms
    Jean Raymond
    Centre de Recherche, Centre Hospitalier de l Universite de Montreal, Hopital Notre Dame, 1560 Sherbrooke Street East, Montreal, Quebec, H2L 4M1 Canada
    AJNR Am J Neuroradiol 23:129-38. 2002
    ..Cyanoacrylates are effective occlusive agents in neurovascular interventions. To study their potential to improve long-term results of endovascular treatment of aneurysms, we conducted experimental studies in canine aneurysm models...
  43. ncbi Selective treatment of an anterior spinal artery aneurysm with endosaccular coil therapy. Case report
    Pascale Lavoie
    Department of Surgery, Neurosurgery Service, Universite Laval, Quebec, Canada
    J Neurosurg Spine 6:460-4. 2007
    ..When the morphological features of a spinal aneurysm and its relation with the anterior spinal axis are favorable, selective endosaccular coil placement can successfully be achieved...
  44. ncbi Ex vivo gene therapy with adenovirus-mediated transforming growth factor beta1 expression for endovascular treatment of aneurysm: results in a canine bilateral aneurysm model
    Edith Ribourtout
    Research Center, Centre Hospitalaire de l Université, de Montréal, Notre Dame Hospital, Montreal, Canada
    J Vasc Surg 38:576-83. 2003
    ..The purpose of this study was to determine the effects of recombinant transforming growth factor beta(1) (rTGFbeta(1)) secreted by transplanted autologous vascular smooth muscle cells (VSMC) on results of endovascular treatment...
  45. ncbi Endovascular treatment with flow diverters may fail to occlude experimental bifurcation aneurysms
    Jean Raymond
    Department of Radiology, Notre Dame Hospital, Centre Hospitalier de l Universite de Montreal, 1560 Sherbrooke East, Montreal, QC, H2L 4M1, Canada
    Neuroradiology 55:1355-63. 2013
    ..Animal models may explain how stents and flow diverters (FDs) may succeed or fail to treat bifurcation aneurysms...
  46. ncbi Cold hibernated elastic memory foams for endovascular interventions
    Annick Metcalfe
    Interventional Neuroradiology Laboratory, CHUM Research Center, Notre Dame Hospital, Mailloux Pavilion M 8206, 1560 Sherbrooke East, Montreal, Que, Canada H2L 4M1
    Biomaterials 24:491-7. 2003
    ..The foamy nature of CHEM favours the ingrowth of cells involved in neointima formation. New devices for endovascular interventions could be designed using CHEM's unique physical properties...
  47. doi The design of the STenting in Aneurysm Treatments (STAT) trial
    Tim E Darsaut
    Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Department of Radiology, Montreal, Quebec, Canada
    J Neurointerv Surg 4:178-81. 2012
    ..TRIAL REGISTRATION NO: ClinicalTrials.gov Identifier: NCT01340612...
  48. doi Flow diverters failing to occlude experimental bifurcation or curved sidewall aneurysms: an in vivo study in canines
    Tim E Darsaut
    Department of Radiology, Centre Hospitalier de l Université de Montréal Notre Dame Hospital, Montreal, Quebec
    J Neurosurg 117:37-44. 2012
    ..The authors designed a modular aneurysm model in canines to address this problem...
  49. ncbi Effect of radioactivity on stent-graft incorporation after endovascular treatment of aneurysms: An animal study
    Sophie Lerouge
    Laboratory of Endovascular Biomaterials, Research Center, University of Montreal Hospital, 1560 Sherbrooke Street East, Montreal, Quebec H2L 4M1, Canada
    J Biomed Mater Res A 79:731-9. 2006
    ..Alteration of external graft surface was observed after ion implantation. Ion implantation of (32)P on SGs does not seem to be a viable strategy to improve incorporation and prevent type-I endoleak after EVAR...
  50. ncbi Y-crossing of braided stents with stents and flow diverters does not cause significant stenosis in bench-top studies
    Alina Makoyeva
    Department of Radiology, University of Montreal, CHUM Notre Dame Hospital Montreal, Quebec, Canada
    Interv Neuroradiol 19:455-60. 2013
    ..Different bifurcation angles had no influence on the occurrence of stenosis. Y-stent placement to treat arterial bifurcations using braided self-expanding stents and FDs does not lead to significant stenosis in bench-top studies. ..
  51. ncbi Endovascular treatment of pericallosal aneurysms
    Thanh N Nguyen
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Quebec, Canada
    J Neurosurg 107:973-6. 2007
    ..The objective of the study was to compare risks of coil therapy and the recurrence rate of pericallosal artery aneurysms with aneurysms in other intradural locations...
  52. ncbi Arterial Onyx embolisation of intracranial DAVFs with cortical venous drainage
    Jason Chew
    Division of Neuroradiology, Department of Radiology, Vancouver General Hospital, Vancouver, BC, Canada
    Can J Neurol Sci 36:168-75. 2009
    ..To present our experience with the endovascular management of intracranial dural arteriovenous fistulas with direct cortical venous drainage by trans-arterial embolisation using Onyx...
  53. ncbi Endovascular aortic aneurysm repair with stent-grafts: experimental models can reproduce endoleaks
    Sophie Lerouge
    Research Center, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, JA de Seve Building, 1560 Sherbrooke East, Montreal, Quebec H2L 4M1, Canada
    J Vasc Interv Radiol 15:971-9. 2004
    ..To develop canine aneurysm models that can reproduce type II endoleaks after endovascular aneurysm repair (EVAR) with stent-grafts...
  54. ncbi Carotid ophthalmic aneurysm rupture after parent vessel occlusion
    Frederick Vincent
    Department of Radiology, University of Montreal, Notre Dame Hospital CHUM, Canada
    AJNR Am J Neuroradiol 26:1372-4. 2005
    ..We report causes leading to and rupture of a carotid ophthalmic aneurysm after treatment by parent vessel occlusion. The aneurysm was initially symptomatic but unruptured...
  55. doi Deep vein thrombosis resolution is impaired in diet-induced type 2 diabetic mice
    Fatiha Bouzeghrane
    Centre Hospitalier de L Universite de Montreal Research Center, Notre Dame Hospital, Montreal, Quebec, Canada
    J Vasc Surg 48:1575-84. 2008
    ..We sought to determine whether diet-induced type 2 diabetes mellitus affects deep venous thrombosis (DVT) resolution in a murine model...
  56. ncbi Gene therapy and endovascular treatment of intracranial aneurysms
    Edith Ribourtout
    Department of Radiology, Centre Hospitalier de l Université de Montréal Hôpital Notre Dame, Montreal, Quebec, Canada
    Stroke 35:786-93. 2004
    ..Gene therapy may improve healing after embolization, and endovascular approaches may offer future in situ delivery systems designed to prevent aneurysm rupture...
  57. doi Endovascular treatment of intracranial unruptured aneurysms: systematic review and meta-analysis of the literature on safety and efficacy
    Olivier N Naggara
    International Consortium of Neuroendovascular Centres, Interventional Neuroradiology Research Unit, Department of Radiology, University of Montreal, CHUM Notre Dame Hospital, Montreal, QC, Canada
    Radiology 256:887-97. 2010
    ....
  58. ncbi Use of the trispan device to assist coil embolization of high-flow arteriovenous fistulas
    Alain Weill
    Centre Hospitalier Universite de Montreal, Pavillon Notre Dame, Radiology Department, Interventional Neuroradiology Unit, Canada
    AJNR Am J Neuroradiol 23:1149-52. 2002
    ..We describe another application of this device to control coil deposition and to prevent coil migration during transvenous occlusion of high-flow arteriovenous fistulas...
  59. doi Transvenous embolization of a symptomatic venous aneurysm developing in the drainage network of a deep cerebral AVM: a case report
    Yves Benabu
    Department of Diagnostic Radiology, Laval University, Quebec, Quebec, Canada
    J Neuroimaging 20:373-5. 2010
    ..The venous aneurysm was treated selectively with platinum coils using a venous approach...
  60. ncbi 32P-oligodeoxynucleotide-coated coils to prevent arterial recanalization after embolization
    Luc Levesque
    Angiogene Inc, Montreal, Quebec, Canada
    AJNR Am J Neuroradiol 25:1062-6. 2004
    ..Endovascular treatment of aneurysms with coils, a less invasive alternative to surgery, is too often associated with recurrences. In a canine model, recanalization after coil embolization can be inhibited by in situ beta radiation...
  61. pmc A trial on unruptured intracranial aneurysms (the TEAM trial): results, lessons from a failure and the necessity for clinical care trials
    Jean Raymond
    Centre Hospitalier de l Universite de Montreal CHUM, Notre Dame Hospital, Department of Radiology, Montreal, Quebec, Canada
    Trials 12:64. 2011
    ..A special status should be reserved for what we would call 'clinical care trials', if we are to practice in a transparent and prospective fashion a medicine that leads to demonstrably better patient outcomes...
  62. ncbi Scales, agreement, outcome measures, and progress in aneurysm therapy
    Jean Raymond
    Centre Hospitalier de l Universite de Montreal, Canada
    AJNR Am J Neuroradiol 28:501-2. 2007
  63. doi Safety and occlusion rates of surgical treatment of unruptured intracranial aneurysms: a systematic review and meta-analysis of the literature from 1990 to 2011
    Marc Kotowski
    Department of Radiology, Centre Hospitalier de l Universite de Montreal CHUM, Notre Dame Hospital, Montreal, Canada
    J Neurol Neurosurg Psychiatry 84:42-8. 2013
    ..We performed an updated systematic review and meta-analysis on the surgical treatment of UIAs, in an attempt to determine the aneurysm occlusion rates and safety of surgery in the modern era...
  64. ncbi Neck-bridge device for endovascular treatment of wide-neck bifurcation aneurysms: initial experience
    J Raymond
    Department of Radiology, Centre Hospitalier de l Universite de Montreal, Hopital Notre Dame, M 8206, 1560 Sherbrooke St East, Montreal, Quebec H2L 4M1, Canada
    Radiology 221:318-26. 2001
    ..To report the authors' initial experience in treating patients with wide-neck aneurysms with assistance from a recently developed neck-bridge device (TriSpan; Target Therapeutics/Boston Scientific, Fremont, Calif)...
  65. pmc The design of the Canadian UnRuptured Endovascular versus Surgery (CURES) trial
    Tim E Darsaut
    Notre Dame Hospital, Department of Radiology, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Can J Neurol Sci 38:236-41. 2011
    ..However, there is no randomized data available to compare the results of surgery versus endovascular treatment of unruptured aneurysms (UIAs)...
  66. ncbi Endovascular treatment of unruptured aneurysms
    D Roy
    Department of Radiology, University of Montreal, Quebec, Canada
    Stroke 32:1998-2004. 2001
    ..We sought to better define the morbidity of endovascular Guglielmi detachable coil (GDC) treatment of unruptured cerebral aneurysms and to discuss its role in the prevention of subarachnoid hemorrhage...
  67. ncbi Trial on endovascular treatment of unruptured aneurysms (TEAM): study monitoring and rationale for trial interruption or continuation
    J Raymond
    Department of Radiology, Interventional Neuroradiology Research Unit INRU, Universite de Montreal, CHUM Notre Dame Hospital, 1560 Sherbrooke East, suite M 8203, H2L 4M1, Montreal, Quebec, Canada
    J Neuroradiol 34:33-41. 2007
    ..We conclude that insufficient recruitment is the sole realistic event that could lead to premature interruption. This review may provide a deeper understanding of the principles justifying the necessity of the study...
  68. ncbi Reflections on the TEAM trial: why clinical care and research should be reconciled
    Jean Raymond
    Notre Dame Hospital, Department of Radiology, Centre Hospitalier de l Universite de Montreal, Montreal, Quebec, Canada
    Can J Neurol Sci 38:198-202. 2011
    ..This may require a major change in the mentalities of clinicians, scientists, and patients alike, and the adoption of novel strategies for public agencies to support the integration of clinical research and care...
  69. ncbi Distal superior cerebellar artery aneurysm presenting with cerebellar infarction: report of two cases
    M Danet
    Department of Radiology, , , Quebec, Canada
    AJNR Am J Neuroradiol 22:717-20. 2001
    ..We describe the clinical and radiologic presentation of these aneurysms and discuss their pathogenesis, diagnosis, and treatment...
  70. doi A new canine carotid artery bifurcation aneurysm model for the evaluation of neurovascular devices
    O Naggara
    Interventional Neuroradiology Research Unit, Department of Radiology, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Canada
    AJNR Am J Neuroradiol 31:967-71. 2010
    ..Our first task was to verify that recurrences occurred after satisfactory coiling. A second aim of this preliminary work was to assess if the new model could recreate the technical challenges involved in bifurcation aneurysms...
  71. ncbi An approach to recurrent aneurysms following endovascular coiling
    Jean Raymond
    Department of Radiology and Interventional Neuroradiology Research Unit, Centre Hospitalier de l Universite de Montreal CHUM, Notre Dame Hospital, Montreal, Quebec, Canada
    J Neurointerv Surg 3:314-8. 2011
    ....
  72. doi Endovascular coiling of cerebral aneurysms using "bioactive" or coated-coil technologies: a systematic review of the literature
    P M White
    International Consortium of Neuroendovascular Centres, Interventional Neuroradiology Research Unit, Department of Radiology, University of Montreal, CHUM Notre Dame Hospital, Montreal, Canada
    AJNR Am J Neuroradiol 30:219-26. 2009
    ..This systematic review illustrates the failure of the industry, the regulatory authorities, and the neurointerventional community combined to provide a reliable and prudent approach to the introduction of new devices...
  73. doi In vivo experimental intracranial aneurysm models: a systematic review
    F Bouzeghrane
    Research Center, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, Quebec, Canada
    AJNR Am J Neuroradiol 31:418-23. 2010
    ..A standardized multicenter study is needed to improve the preclinical evaluation of endovascular devices in aneurysm therapy...
  74. ncbi Inter- and intraobserver variability in the assessment of brain arteriovenous malformation angioarchitecture and endovascular treatment results
    D Iancu-Gontard
    Department of Radiology, Interventional Neuroradiology Section, Centre Hospitalier de l Universite de Montreal, Notre Dame Hospital, Montreal, PQ, Canada
    AJNR Am J Neuroradiol 28:524-7. 2007
    ..However, interpretation of these features may not be consistent between observers. We conducted a study to determine inter- and intraobserver agreement of various angioarchitectural characteristics of BAVM...
  75. ncbi Unruptured intracranial aneurysms: a call for a randomized clinical trial
    Jean Raymond
    AJNR Am J Neuroradiol 27:242-3. 2006
  76. doi Complete occlusion remains the primary goal of endovascular coiling of intracranial aneurysms
    Francois Guilbert
    Radiology 246:643. 2008
  77. ncbi Radioactive coil embolization of intracranial aneurysms: minimal inventory to reach target activities in a virtual series of 154 patients
    Charbel Mounayer
    Department of Interventional Neuroradiology Fondation Ophtalmique Adolphe Rothschild, Paris, France
    AJNR Am J Neuroradiol 25:1377-80. 2004
    ..A limited supply of three or four types of coils may decrease the inventory difficulties related to the use of an isotope with a half-life of 2 weeks...
  78. ncbi Transcatheter embolization using degradable crosslinked hydrogels
    Alexander Schwarz
    Biosphere Medical, Inc, 1050 Hingham Street, Rockland, MA 02370, USA
    Biomaterials 25:5209-15. 2004
    ..Advantages of temporary embolization were not convincingly demonstrated since temporary occlusions still led to tissue infarction...
  79. doi The color of ruptures
    Thanh N Nguyen
    Stroke 39:e136; author reply e137. 2008
  80. doi Association of endovascular therapy of very small ruptured aneurysms with higher rates of procedure-related rupture
    Thanh N Nguyen
    Department of Neurology, Neurosurgery, and Radiology, Boston University Medical Center, Boston, MA, USA
    J Neurosurg 108:1088-92. 2008
    ..Previously ruptured aneurysms are a known risk factor for procedure-related rupture. The objective of this study was to evaluate whether very small, ruptured aneurysms are associated with more frequent intraprocedural ruptures...
  81. doi Medical applications of shape memory polymers
    Witold Sokolowski
    Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91109, USA
    Biomed Mater 2:S23-7. 2007
    ..Lately, several important applications are being considered for CHEM foams as self-deployable vascular and coronary devices. One example is the endovascular treatment of aneurysms...
  82. ncbi Safety, science, and sales: a request for valid clinical trials to assess new devices for endovascular treatment of intracranial aneurysms
    Jean Raymond
    AJNR Am J Neuroradiol 25:1128-30. 2004
  83. doi Unruptured intracranial aneurysms: evidence and speculations
    Jean Raymond
    Radiology 247:294; author reply 294. 2008
  84. ncbi Impact of surgical treatment of unruptured aneurysms
    Jean Raymond
    Stroke 36:2069-70. 2005