Didier Raoult

Summary

Publications

  1. ncbi request reprint Common subclinical hypothyroidism during Whipple's disease
    Jean Christophe Lagier
    Aix Marseille Universite, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Faculte de Medecine, 27 Bd Jean Moulin, 13005 Marseille, France
    BMC Infect Dis 14:370. 2014
  2. pmc Variations of plasmid content in Rickettsia felis
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48, CNRS IRD UMR 6236, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 3:e2289. 2008
  3. pmc Coxiella burnetii in humans and ticks in rural Senegal
    Oleg Mediannikov
    URMITE, UMR IRD 198 CNRS 6236, Mediterranean University, Medical Faculty, Marseille, France
    PLoS Negl Trop Dis 4:e654. 2010
  4. pmc A new method to extract dental pulp DNA: application to universal detection of bacteria
    Lam Tran-Hung
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 2:e1062. 2007
  5. pmc The giant Cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of Life
    Philippe Colson
    Centre National de la Recherche Scientifique Unité Mixte de Recherche 6236, Institut de Recherche pour le Développement 3R198, Facultes de Medecine et de Pharmacie, Universite de la Mediterranee, Marseille, France
    PLoS ONE 6:e18935. 2011
  6. pmc Tick-borne relapsing fever borreliosis, rural senegal
    Philippe Parola
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 17:883-5. 2011
  7. pmc Evidence for an African cluster of human head and body lice with variable colors and interbreeding of lice between continents
    Aurélie Veracx
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UMR CNRS 6236, IRD 198, IFR48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 7:e37804. 2012
  8. pmc Seasonality of cat-scratch disease, France, 1999-2009
    Diane Sanguinetti-Morelli
    Université de Méditerranée, Marseille, France
    Emerg Infect Dis 17:705-7. 2011
  9. pmc Q fever in France, 1985-2009
    Diane Frankel
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 17:350-6. 2011
  10. pmc Coxiella burnetii transcriptional analysis reveals serendipity clusters of regulation in intracellular bacteria
    Quentin Leroy
    Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes, Faculte de Medecine, CNRS IRD, UMR 6236, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e15321. 2010

Detail Information

Publications258 found, 100 shown here

  1. ncbi request reprint Common subclinical hypothyroidism during Whipple's disease
    Jean Christophe Lagier
    Aix Marseille Universite, URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Faculte de Medecine, 27 Bd Jean Moulin, 13005 Marseille, France
    BMC Infect Dis 14:370. 2014
    ..whipplei carriage occurs in 2-4% of the general population in France. Subclinical hypothyroidism, characterized by high levels of TSH and normal free tetra-iodothyronine (fT4) dosage, has been rarely associated with specific HLA factors...
  2. pmc Variations of plasmid content in Rickettsia felis
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48, CNRS IRD UMR 6236, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 3:e2289. 2008
    ..In a recent article, Gillespie et al. (PLoS One. 2007;2(3):e266.) used a bioinformatic approach to refute the presence of the second plasmid form, and proposed the creation of a specific phylogenetic group for R. felis...
  3. pmc Coxiella burnetii in humans and ticks in rural Senegal
    Oleg Mediannikov
    URMITE, UMR IRD 198 CNRS 6236, Mediterranean University, Medical Faculty, Marseille, France
    PLoS Negl Trop Dis 4:e654. 2010
    ..Q fever is a worldwide zoonotic disease caused by Coxiella burnetii. Epidemiologically, animals are considered reservoirs and humans incidental hosts...
  4. pmc A new method to extract dental pulp DNA: application to universal detection of bacteria
    Lam Tran-Hung
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 2:e1062. 2007
    ..Current protocols require odontology expertise for proper recovery of the dental pulp. Dental pulp specimen exposed to laboratory environment yields contaminants detected using universal 16S rDNA-based detection of bacteria...
  5. pmc The giant Cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of Life
    Philippe Colson
    Centre National de la Recherche Scientifique Unité Mixte de Recherche 6236, Institut de Recherche pour le Développement 3R198, Facultes de Medecine et de Pharmacie, Universite de la Mediterranee, Marseille, France
    PLoS ONE 6:e18935. 2011
    ..Recently, the genome of a new NCLDV, Cafeteria roenbergensis virus (CroV), was released. The present work aimed to determine if CroV supports the fourth domain of Life hypothesis...
  6. pmc Tick-borne relapsing fever borreliosis, rural senegal
    Philippe Parola
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 17:883-5. 2011
    ....
  7. pmc Evidence for an African cluster of human head and body lice with variable colors and interbreeding of lice between continents
    Aurélie Veracx
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UMR CNRS 6236, IRD 198, IFR48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 7:e37804. 2012
    ..Mitochondrial genetic analysis reclassified lice into three genotypes (A, B and C). However, no previous study has attempted to correlate both genotypic and phenotypic data...
  8. pmc Seasonality of cat-scratch disease, France, 1999-2009
    Diane Sanguinetti-Morelli
    Université de Méditerranée, Marseille, France
    Emerg Infect Dis 17:705-7. 2011
    ..To assess the seasonality of the disease in France, we analyzed lymph node biopsy specimens collected during 1999-2009. Most (87.5%) cases occurred during September-April and peaked in December...
  9. pmc Q fever in France, 1985-2009
    Diane Frankel
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 17:350-6. 2011
    ..Annual incidences of acute Q fever and endocarditis were 2.5/100,000 persons and 0.1/100,000 persons, respectively. Cases and outbreaks of Q fever have increased in France...
  10. pmc Coxiella burnetii transcriptional analysis reveals serendipity clusters of regulation in intracellular bacteria
    Quentin Leroy
    Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes, Faculte de Medecine, CNRS IRD, UMR 6236, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e15321. 2010
    ..burnetii observed under temperature stresses permits the recognition of unpredicted clusters of regulation for which the trigger mechanism remains unidentified but which may be the result of a new mechanism of epigenetic regulation...
  11. pmc Identification of rickettsial infections by using cutaneous swab specimens and PCR
    Yassina Bechah
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 17:83-6. 2011
    ..Specimens from eschars in guinea pigs were positive for rickettsiae as long as lesions were present. Optimal storage temperature for specimens was 4 degrees C for 3 days...
  12. pmc Defining pathogenic bacterial species in the genomic era
    Kalliopi Georgiades
    Faculte de Medecine et de Pharmacie, Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, CNRS IRD, UMR 6236, IFR48 Marseille, France
    Front Microbiol 1:151. 2010
    ..It is likely that current bacterial pathogens will disappear soon and be replaced by new ones that will emerge from bacterial complexes that are already in contact with humans...
  13. pmc Revolutionizing clinical microbiology laboratory organization in hospitals with in situ point-of-care
    Stephan Cohen-Bacrie
    Fédération de Microbiologie Clinique, Assistance Publique des Hôpitaux de Marseille Pôle des Maladies Infectieuses, Hopital La Timone, Marseille, France
    PLoS ONE 6:e22403. 2011
    ..Clinical microbiology may direct decisions regarding hospitalization, isolation and anti-infective therapy, but it is not effective at the time of early care. Point-of-care (POC) tests have been developed for this purpose...
  14. pmc Comparison of real-time quantitative PCR and culture for the diagnosis of emerging rickettsioses
    Emmanouil Angelakis
    URMITE UMR 6236, CNRS IRD, Faculte de Medecine et de Pharmacie, Marseille, France
    PLoS Negl Trop Dis 6:e1540. 2012
    ..Isolation of Rickettsia species from skin biopsies may be replaced by PCR. We evaluated culture sensitivity compared to PCR based on sampling delay and previous antibiotic treatment...
  15. pmc Immuno-PCR--a new tool for paleomicrobiology: the plague paradigm
    Nada Malou
    Aix Marseille Universite, URMITE, UMR CNRS 6236 IRD 198, Faculte de Medecine, Marseille, France
    PLoS ONE 7:e31744. 2012
    ..However, the degradation of DNA limits the ability to detect ancient infections...
  16. pmc Legionella longbeachae and endocarditis
    Nicola Leggieri
    Laboratoire de Microbiologie, Centre Hospitalier Universitaire de la Timone, 264 rue Saint Pierre, 13385 Marseille Cedex 5, France
    Emerg Infect Dis 18:95-7. 2012
    ..It is commonly found in composted waste wood products. L. longbeachae should be regarded as an agent of infectious endocarditis, notably in the context of gardening involving handling of potting soils...
  17. pmc Altitude-dependent Bartonella quintana genotype C in head lice, Ethiopia
    Emmanouil Angelakis
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 17:2357-9. 2011
    ..B. quintana was found in 19 (7%) genotype C head lice and in 76 (18%) genotype A body lice. B. quintana in head lice was positively linked to altitude (p = 0.014)...
  18. pmc Effect of rickettsial toxin VapC on its eukaryotic host
    Gilles Audoly
    Unité des Rickettsies URMITE, UMR CNRS 6236 IRD 198, Marseille, France
    PLoS ONE 6:e26528. 2011
    ..Our results suggest that early mortality following antibiotic treatment of some bacterial infections can be prevented by administration of dexamethasone...
  19. pmc Genomotyping of Coxiella burnetii using microarrays reveals a conserved genomotype for hard tick isolates
    Quentin Leroy
    Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes, CNRS IRD, UMR 6236, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 6:e25781. 2011
    ..Serendipitously, the genomotyping results revealed that all hard tick isolates, including the Nine Mile strain, belong to the same genomotype...
  20. pmc Rickettsia honei infection in human, Nepal, 2009
    HOLLY MURPHY
    Canadian International Water and Energy Consultants Clinic Travel Medicine Center, Kathmandu, Nepal
    Emerg Infect Dis 17:1865-7. 2011
    ..Diagnosis was confirmed by indirect immunofluorescent assay with serum and molecular biological techniques. Flinders Island spotted fever may be an endemic rickettsiosis in Nepal...
  21. pmc Phylogenomic analysis of Odyssella thessalonicensis fortifies the common origin of Rickettsiales, Pelagibacter ubique and Reclimonas americana mitochondrion
    Kalliopi Georgiades
    Unité de Recherche en Maladies Infectieuses Tropicales Emergentes, CNRS IRD UMR 6236, Faculté de la Médecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 6:e24857. 2011
    ..Recently, the whole genome of O. thessalonicensis has been sequenced, and 16S rDNA phylogeny and more robust and accurate phylogenomic analyses have been performed with 65 highly conserved proteins...
  22. pmc Obesity-associated gut microbiota is enriched in Lactobacillus reuteri and depleted in Bifidobacterium animalis and Methanobrevibacter smithii
    M Million
    URMITE CNRS UMR 6236 IRD 198, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 27 Bd Jean Moulin, Marseille, France
    Int J Obes (Lond) 36:817-25. 2012
    ....
  23. pmc Phylogenetic and phyletic studies of informational genes in genomes highlight existence of a 4 domain of life including giant viruses
    Mickael Boyer
    URMITE, Centre National de la Recherche Scientifique UMR IRD 6236, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e15530. 2010
    ..We hypothesize that the core genome of NCLDV is as ancient as the three currently accepted domains of life...
  24. pmc Evidence of a louse-borne outbreak involving typhus in Douai, 1710-1712 during the war of Spanish succession
    Tung Nguyen-Hieu
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UMR CNRS 6236, IRD198, IFR48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e15405. 2010
    ..The new field of paleomicrobiology allows past outbreaks to be identified by testing dental pulp of human remains with PCR...
  25. pmc Potential for tick-borne bartonelloses
    Emmanouil Angelakis
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 16:385-91. 2010
    ..However, there is little evidence that Bartonella spp. can replicate within ticks and no definitive evidence of transmission by a tick to a vertebrate host...
  26. pmc Vancomycin treatment of infective endocarditis is linked with recently acquired obesity
    Franck Thuny
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e9074. 2010
    ..We tested the effect of antibiotics given for infective endocarditis (IE) on weight gain (WG)...
  27. pmc Tropheryma whipplei in fecal samples from children, Senegal
    Florence Fenollar
    Universite de la Mediterranee, Marseille, France
    Emerg Infect Dis 15:922-4. 2009
    ..Unique genotypes were associated with this bacterium. Our findings suggest that T. whipplei is emerging as a highly prevalent pathogen in sub-Saharan Africa...
  28. pmc Tropheryma whipplei in patients with pneumonia
    Sabri Bousbia
    CNRS IRD Faculte de Medecine, Marseille, France
    Emerg Infect Dis 16:258-63. 2010
    ..We identified 4 novel genotypes of T. whipplei. In 1 case, T. whipplei was the only bacterium; in 4 others, it was associated with buccal flora. We suggest that T. whipplei should be investigated as an etiologic agent of pneumonia...
  29. pmc Rickettsia slovaca and R. raoultii in tick-borne Rickettsioses
    Philippe Parola
    Unite des Rickettsies, Marseille, France
    Emerg Infect Dis 15:1105-8. 2009
    ..We identified the etiologic agent for 65% of 86 patients with TIBOLA/DEBONEL as either Rickettsia slovaca (49/86, 57%) or R. raoultii (7/86, 8%)...
  30. pmc Warmer weather linked to tick attack and emergence of severe rickettsioses
    Philippe Parola
    Unité de Recherche en Maladies Infectieuses et Tropicales Emergentes, CNRS IRD UMR 6236, WHO Collaborative Centre for Rickettsial and Other Arthropod Borne Bacterial Diseases, Faculte de Medecine, Marseille, France
    PLoS Negl Trop Dis 2:e338. 2008
    ..sanguineus, leading to increased human attacks. From a global perspective, we predict that as a result of globalisation and warming, more pathogens transmitted by the brown dog tick may emerge in the future...
  31. pmc Development and assessment of a new early scoring system using non-specific clinical signs and biological results to identify children and adult patients with a high probability of infective endocarditis on admission
    Herve Richet
    Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, 27 Boulevard Jean Moulin, 13385 Marseille Cedex 05, France
    J Antimicrob Chemother 62:1434-40. 2008
    ..The aim of this study was to assess whether non-specific clinical signs or biological results can identify patients with a high probability of infective endocarditis (IE) to improve outcome...
  32. pmc A novel obligate intracellular gamma-proteobacterium associated with ixodid ticks, Diplorickettsia massiliensis, Gen. Nov., Sp. Nov
    Oleg Mediannikov
    Unité des Recherches sur les Maladies Infectieuses et Emergentes, Centre National de la Recherche Scientifique 6236, Institut de Recherche pour le Développement 198, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e11478. 2010
    ..Obligate intracellular bacteria of arthropods often exhibit a significant role in either human health or arthropod ecology...
  33. pmc Rickettsia felis-associated uneruptive fever, Senegal
    Cristina Socolovschi
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, 13385 Marseille, France
    Emerg Infect Dis 16:1140-2. 2010
    ..Using molecular tools, we found evidence for Rickettsia felis-associated illness in the initial days of infection in febrile Senegalese patients without malaria...
  34. pmc Detection of plant DNA in the bronchoalveolar lavage of patients with ventilator-associated pneumonia
    Sabri Bousbia
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, Faculte de Medecine, CNRS IRD UMR 6236 198, Marseille, France
    PLoS ONE 5:e11298. 2010
    ..Herein, we found by molecular technique that vegetable and tobacco DNA may be detected in the bronchoalveolar lavage from patients with ventilator-associated pneumonia (VAP)...
  35. pmc The increase of Lactobacillus species in the gut flora of newborn broiler chicks and ducks is associated with weight gain
    Emmanouil Angelakis
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e10463. 2010
    ..The objective of our study was to determine if increased Lactobacillus sp. in the gut flora of newborn broiler chicks and ducks could result in weight gain increase...
  36. pmc Pepper mild mottle virus, a plant virus associated with specific immune responses, Fever, abdominal pains, and pruritus in humans
    Philippe Colson
    Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes URMITE, Centre National de la Recherche Scientifique CNRS Unité Mixte de Recherche UMR 6236 Institut de Recherche pour le Développement IRD 3R198, Facultes de Medecine et de Pharmacie, Universite de la Mediterranee, Marseille, France
    PLoS ONE 5:e10041. 2010
    ..Recently, metagenomic studies have identified viable Pepper mild mottle virus (PMMoV), a plant virus, in the stool of healthy subjects. However, its source and role as pathogen have not been determined...
  37. pmc Bartonella quintana and Coxiella burnetii as causes of endocarditis, India
    Nandhakumar Balakrishnan
    Emerg Infect Dis 14:1168-9. 2008
  38. pmc Genotyping of human lice suggests multiple emergencies of body lice from local head louse populations
    Wenjun Li
    URMITE, UMR CNRS 6236, IRD 198, Universite de la Mediterranee, Faculte de Medecine, Marseille, France
    PLoS Negl Trop Dis 4:e641. 2010
    ..Recent studies suggest that body lice arose several times from head louse populations...
  39. pmc Monitoring bacterial community of human gut microbiota reveals an increase in Lactobacillus in obese patients and Methanogens in anorexic patients
    Fabrice Armougom
    URMITE UMR CNRS 6236, IRD 3R198, Universite de la Mediterranee, Faculte de Medecine, and Nutrition and Diabetology Department, University Hospital Sainte Marguerite, Marseille, France
    PLoS ONE 4:e7125. 2009
    ..The roles of the archaeon Methanobrevibacter smithii and Lactobacillus species have not been described in these studies...
  40. pmc Partial disruption of translational and posttranslational machinery reshapes growth rates of Bartonella birtlesii
    Jean Marc Rolain
    URMITE CNRS IRD, URMITE 6236, Méditerranée Infection, Faculte de Medecine et de Pharmacie, Aix Marseille Universite, Marseille, France
    MBio 4:e00115-13. 2013
    ..Finally, one of the four clones did not induce bacteremia in our mouse model, whereas infection with the other three resulted in a significantly lower bacterial count in blood than that with the wild-type strain...
  41. pmc Molecular evidence for the presence of Rickettsia Felis in the feces of wild-living African apes
    Alpha Kabinet Keita
    Aix Marseille Universite, Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes URMITE UM63, CNRS 7278, IRD 198, INSERM 1095, Marseille, France
    PLoS ONE 8:e54679. 2013
    ..We hypothesized that, as with malaria, great apes may be exposed to the infectious bite of infected mosquitoes and release R. felis DNA in their feces...
  42. pmc Human gut microbiota: repertoire and variations
    Jean Christophe Lagier
    URMITE, UM63, CNRS 7278, L Institut de Recherche pour le Développement 198, INSERM 1095, Aix Marseille Université Marseille, France
    Front Cell Infect Microbiol 2:136. 2012
    ....
  43. pmc Unique clone of Coxiella burnetii causing severe Q fever, French Guiana
    Aba Mahamat
    Centre Hospitalier Andrée Rosemon, Cayenne, French Guiana
    Emerg Infect Dis 19:1102-4. 2013
    ..This clone has caused pneumonia and endocarditis and seems to be more virulent than previously described strains...
  44. pmc Common epidemiology of Rickettsia felis infection and malaria, Africa
    Oleg Mediannikov
    These authors contributed equally to this article
    Emerg Infect Dis 19:1775-83. 2013
    ....
  45. pmc Emergence of q Fever
    E Angelakis
    Unite des Rickettsies, CNRS UMR 6020, IFR 48, Faculte de Medecine, Universite de la Mediterranee, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France
    Iran J Public Health 40:1-18. 2011
    ..For the treatment of Q fever during pregnancy the use of long-term cotrimoxazole therapy is proposed...
  46. pmc Molecular detection of Acinetobacter species in lice and keds of domestic animals in Oromia Regional State, Ethiopia
    Bersissa Kumsa
    Department of Parasitology, College of Veterinary Medicine and Agriculture, Addis Ababa University, Bishoftu, Ethiopia
    PLoS ONE 7:e52377. 2012
    ..infections in humans. However, additional epidemiological data are required to determine whether ectoparasites of animals can act as environmental reservoirs and play a role in spreading these bacteria to both animal and human hosts...
  47. pmc Borrelia recurrentis in head lice, Ethiopia
    Amina Boutellis
    Marseille Université, Marseille, France
    Emerg Infect Dis 19:796-8. 2013
    ..In 2011, we found B. recurrentis DNA in 23% of head lice from patients with louse-borne relapsing fever in Ethiopia. Whether head lice can transmit these bacteria from one person to another remains to be determined...
  48. pmc Correlation between body mass index and gut concentrations of Lactobacillus reuteri, Bifidobacterium animalis, Methanobrevibacter smithii and Escherichia coli
    M Million
    1 URMITE, UM63, CNRS 7278, IRD 198, INSERM 1095, Aix Marseille Universite, Marseille, France 2 APHM, CHU Timone, Pôle Infectieux, Marseille, France
    Int J Obes (Lond) 37:1460-6. 2013
    ..Bifidobacterium genus members have been associated with a lean status, whereas different Lactobacillus species are associated both with a lean and an obese status...
  49. pmc Point-of-care laboratory of pathogen diagnosis in rural Senegal
    Cheikh Sokhna
    URMITE, IRD 198, UM63, CNRS 7278, INSERM 1095, Aix Marseille Universite, Marseille, France
    PLoS Negl Trop Dis 7:e1999. 2013
    ....
  50. pmc DNA persistence and relapses questions on the treatment strategies of Enterococcus infections of prosthetic valves
    Jean Paul Casalta
    URMITE, Aix Marseille Universite, UMR CNRS 7278, IRD 198, INSERM 1095, Faculte de Medecine, Marseille, France
    PLoS ONE 7:e53335. 2012
    ....
  51. pmc Evidence of sympatry of clade a and clade B head lice in a pre-Columbian Chilean mummy from Camarones
    Amina Boutellis
    Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes URMITE, Aix Marseille Universite, UMR CNRS 7278, IRD 198, INSERM 1095 Faculté de Médecine, 27 Bd Jean Moulin, Marseille, France
    PLoS ONE 8:e76818. 2013
    ..Our finding shows that clade B head lice were present in America before the arrival of the European colonists. ..
  52. pmc Dramatic reduction of culture time of Mycobacterium tuberculosis
    Ramzi Ghodbane
    Aix Marseille Universite, URMITE UMR CNRS 7278, IRD 198, INSERM 1095, 13005, Marseille, France
    Sci Rep 4:4236. 2014
    ..In the best case, primary culture and rifampicin susceptibility testing were achieved in 72 hours when specimens were inoculated directly on the medium supplemented by antibiotic at the beginning of the culture...
  53. pmc Rhizome of life, catastrophes, sequence exchanges, gene creations, and giant viruses: how microbial genomics challenges Darwin
    Vicky Merhej
    URMITE, UM63, CNRS 7278, IRD 198, INSERM U1095, Aix Marseille Université Marseille, France
    Front Cell Infect Microbiol 2:113. 2012
    ..A forest, a network or a rhizome of life may be more accurate to represent evolutionary relationships among species...
  54. pmc Lamarckian evolution of the giant Mimivirus in allopatric laboratory culture on amoebae
    Philippe Colson
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, Centre National de la Recherche Scientifique Unité Mixte de Recherche UMR 7278, Institut de Recherche pour le Développement IRD 3R198, INSERM U1095, IHU Méditerranée Infection, Facultes de Medecine et de Pharmacie, Aix Marseille University Marseille, France
    Front Cell Infect Microbiol 2:91. 2012
    ..15%; p = 0.062). Finally, Lamarckian evolution represented the evolutionary process encountered by 63% of the inactivated genes. Such observations may be explained by the lower level of DNA repair of useless genes...
  55. pmc Evidence that head and body lice on homeless persons have the same genotype
    Aurélie Veracx
    URMITE UMR 6236, CNRS IRD, Faculte de Medecine, Universite Aix Marseille, Marseille, France
    PLoS ONE 7:e45903. 2012
    ..These findings confirm that head and body lice are two ecotypes of the same species and show the importance of implementing measures to prevent lice transmission between homeless people in shelters...
  56. pmc Comparative genomics evidence that only protein toxins are tagging bad bugs
    Kalliopi Georgiades
    Unité de Recherche en Maladies Infectieuses Tropical Emergentes URMITE, CNRS IRD UMR 6236 198, Université de la Méditerranée Marseille, France
    Front Cell Infect Microbiol 1:7. 2011
    ..e., the outcome of the loss of regulatory and transcription factors and the presence of protein toxins, alone, or coupled as TA modules...
  57. pmc Acanthamoeba polyphaga mimivirus virophage seroconversion in travelers returning from Laos
    Philippe Parola
    Aix Marseille University, Marseille, France
    Emerg Infect Dis 18:1500-2. 2012
    ..While in Laos, they had eaten raw fish, a potential source of the virophage. This virophage, associated with giant viruses suspected to cause pneumonia, could be an emerging pathogen...
  58. pmc How microbiology helps define the rhizome of life
    Kalliopi Georgiades
    Faculté de médecine La Timone, Unité de Recherche en Maladies Infectieuses Tropical Emergentes URMITE, CNRS IRD UMR 6236 198, Université de la Méditerranée Marseille, France
    Front Cell Infect Microbiol 2:60. 2012
    ..This view of evolution should resemble a clump of roots representing the multiple origins of the repertoires of the genes of each species...
  59. pmc Carbapenem resistance and Acinetobacter baumannii in Senegal: the paradigm of a common phenomenon in natural reservoirs
    Marie Kempf
    Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes URMITE, UMR CNRS 6236, Aix Marseille Universite, Marseille, France
    PLoS ONE 7:e39495. 2012
    ..baumannii detected in stools were all of recA genotype 3 and those detected in lice, of recA genotype 4. This study shows for the first time a reservoir of bla(OXA23-like)-positive gene in human head lice and stool samples in Senegal...
  60. ncbi request reprint Mediterranean spotted fever in Algeria--new trends
    Nadjet Mouffok
    Service des Maladies Infectieuses, Centre Hospitalier Universitaire d Oran, Algeria
    Int J Infect Dis 13:227-35. 2009
    ..We report herein a prospective study conducted in Oran, the second largest city in Algeria. This disease has not been properly described in Oran or in other Algerian cities...
  61. pmc Virophages, polintons, and transpovirons: a complex evolutionary network of diverse selfish genetic elements with different reproduction strategies
    Natalya Yutin
    National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Virol J 10:158. 2013
    ....
  62. pmc Mimiviridae: clusters of orthologous genes, reconstruction of gene repertoire evolution and proposed expansion of the giant virus family
    Natalya Yutin
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Virol J 10:106. 2013
    ..In the light of these findings, a reassessment of the relationships between the mimiviruses and other NCLDV and reconstruction of the evolution of giant virus genomes emerge as interesting and timely goals...
  63. pmc An automated approach for the identification of horizontal gene transfers from complete genomes reveals the rhizome of Rickettsiales
    Phuong Thi Le
    Evolutionary Biology and Modeling, LATP UMR CNRS 7353, Aix Marseille University, 13331, Marseille, France
    BMC Evol Biol 12:243. 2012
    ..Gene gains from both distantly and closely related organisms play crucial roles in the evolution of bacterial genomes. In this work, we focus on genes transferred from distantly related species into Rickettsiales species...
  64. doi request reprint Postgenomic analysis of bacterial pathogens repertoire reveals genome reduction rather than virulence factors
    Vicky Merhej
    Aix Marseille Universite, Marseille, France
    Brief Funct Genomics 12:291-304. 2013
    ..These findings questioned the paradigm of virulence by gene acquisition and put forward the notion of genomic repertoire of virulence. ..
  65. pmc The influence of rickettsiologists on post-modern microbiology
    Kalliopi Georgiades
    Unité de Recherche en Maladies Infectieuses Tropical Emergentes, CNRS IRD UMR 6236 198, Université de la Méditerranée Marseille, France
    Front Cell Infect Microbiol 1:8. 2011
    ....
  66. doi request reprint Plague: history and contemporary analysis
    Didier Raoult
    Aix Marseille Universite, Unite des Rickettsies, UMR CNRS, IRD, INSERM, IHU Méditerranée Infection, France
    J Infect 66:18-26. 2013
    ..Analysis of past plague epidemics by using modern laboratory tools illustrated the value of epidemic buboes for the clinical diagnosis of plague; and brought new concepts regarding its transmission by human ectoparasites...
  67. ncbi request reprint Rapid and accurate bacterial identification in probiotics and yoghurts by MALDI-TOF mass spectrometry
    Emmanouil Angelakis
    CNRS UMR 6020, IFR 48, Faculte de Medecine, Univ de la Méditerranée, 27 Bd Jean Moulin, 13385 Marseille Cedex 05, France
    J Food Sci 76:M568-72. 2011
    ..Although the safety and functionality of probiotics are species and strain dependent, we found a discrepancy between the bacterial strain announced on the label and the strain identified...
  68. pmc Complete genome sequence of Rickettsia slovaca, the agent of tick-borne lymphadenitis
    Pierre Edouard Fournier
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, CNRS UMR 6236, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    J Bacteriol 194:1612. 2012
    ..The 1.27-Mb genome provides further insights into the acquisition of virulence related to genome reduction in Rickettsia species...
  69. pmc Eukaryotic large nucleo-cytoplasmic DNA viruses: clusters of orthologous genes and reconstruction of viral genome evolution
    Natalya Yutin
    National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD 20894, USA
    Virol J 6:223. 2009
    ....
  70. pmc Pseudoclavibacter-like subcutaneous infection: a case report
    François Lemaitre
    Pôle des Maladies Infectieuses, Fédération de Microbiologie Clinique, Hopital de la Timone, rue Saint Pierre, 13005 Marseille, France
    J Med Case Reports 5:468. 2011
    ..abstract:..
  71. pmc Mycoplasma hominis brain abscess following uterus curettage: a case report
    Mouhamad Al Masalma
    Fédération de Microbiologie, Hopital de la Timone, Marseille, France
    J Med Case Reports 5:278. 2011
    ..abstract:..
  72. pmc Actinomadura meyerae osteitis following wound contamination with hay in a woman in France: a case report
    Emilie Bonnet
    Fédération de Microbiologie, Hopital de la Timone, Marseille, France
    J Med Case Reports 5:32. 2011
    ..abstract:..
  73. pmc Nocardia farcinica lung infection in a patient with cystic fibrosis: a case report
    Fadi Bittar
    Unité de Recherche sur les Maladies Infectieuses et Tropicales Emergentes URMITE, CNRS IRD, UMR 6236, Faculte de Medecine et de Pharmacie, Universite de la Mediterranee, Boulevard Jean Moulin, 13385 Marseille Cedex 5, France
    J Med Case Reports 4:84. 2010
    ..Nocardia are rarely implicated in these infections and few reports of the involvement of this species are found in the literature...
  74. pmc Gene gain and loss events in Rickettsia and Orientia species
    Kalliopi Georgiades
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, URMITE, CNRS IRD UMR 6236 IFR48 Faculté de Médecine, Universite de la Mediterranee, Marseille, France
    Biol Direct 6:6. 2011
    ..In this study, we evaluated the degree to which gene loss shaped the content of some Rickettsiales genomes. We shed light on the role played by horizontal gene transfers in the genome evolution of Rickettsiales...
  75. pmc Evidence that the intra-amoebal Legionella drancourtii acquired a sterol reductase gene from eukaryotes
    Claire Moliner
    URMITE CNRS IRD UMR 6236, , 27 Boulevard Jean Moulin, 13385 Marseille, Cedex 05, France
    BMC Res Notes 2:51. 2009
    ..drancourtii and Coxiella burnetii. The role of the sterol delta-7 reductase in prokaryotes is as yet unknown but we speculate that it is involved in host cholesterol parasitism...
  76. pmc Pyrosequencing identification of Mycobacterium tuberculosis W-Beijing
    Zoheira Djelouadji
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UMR CNRS 6236, IRD 3R198, Universite de la Mediterranee, IFR 48, Faculte de Medecine, Marseille, France
    BMC Res Notes 2:239. 2009
    ..Its identification currently relies on spoligotyping and conventional sequencing. We developed pyrosequencing as an alternative method for its identification...
  77. pmc Rapid identification and typing of Yersinia pestis and other Yersinia species by matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry
    Saravanan Ayyadurai
    Unite de Recherche sur les Maladies Infectieuses et Tropicales Emergentes, UMR CNRS 6236 IRD 198, Faculte de Medecine, IFR48, Universite de la Mediterranee, Marseille, France
    BMC Microbiol 10:285. 2010
    ..The organisms were deposited on the MALDI-TOF plate after appropriate ethanol-based inactivation, and a protein profile was obtained within 6 minutes for each of the Yersinia species...
  78. pmc Identification of rickettsial isolates at the species level using multi-spacer typing
    Pierre Edouard Fournier
    Unite des Rickettsies, IFR 48, CNRS UMR 6020, Faculte de Medecine, Universite de la Mediterranee, Marseille Cedex 05, France
    BMC Microbiol 7:72. 2007
    ....
  79. pmc Progressive dementia associated with ataxia or obesity in patients with Tropheryma whipplei encephalitis
    Florence Fenollar
    Unite des Rickettsies, URMITE CNRS IRD UMR 6236, IFR 48, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    BMC Infect Dis 11:171. 2011
    ..Tropheryma whipplei, the agent of Whipple's disease, causes localised infections in the absence of histological digestive involvement. Our objective is to describe T. whipplei encephalitis...
  80. pmc Coxiella burnetii vascular graft infection
    Laurence Senn
    Infectious Diseases Service, Department of Internal Medicine, University Hospital, Lausanne, Switzerland
    BMC Infect Dis 5:109. 2005
    ..Coxiella burnetii, the causative agent of Q fever, may cause culture-negative vascular graft infections. Very few cases of C. burnetii infection of a vascular graft have been reported. All were diagnosed by serology...
  81. pmc Insight into cross-talk between intra-amoebal pathogens
    Gregory Gimenez
    Unite des Rickettsies, Faculte de Medecine, Universite de la Mediterranee, Marseille, France
    BMC Genomics 12:542. 2011
    ..This characteristic is proposed to be the result of frequent gene exchanges with other bacteria that share a sympatric lifestyle and contrasts with the genome reduction observed among strict human pathogens...