Amutha Ramaswamy

Summary

Publications

  1. ncbi request reprint Structural dynamics of nucleosome core particle: comparison with nucleosomes containing histone variants
    Amutha Ramaswamy
    Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio 43210, USA
    Proteins 58:683-96. 2005
  2. pmc Global dynamics of newly constructed oligonucleosomes of conventional and variant H2A.Z histone
    Amutha Ramaswamy
    Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA
    BMC Struct Biol 7:76. 2007
  3. doi request reprint Conformational analysis on the wild type and mutated forms of human ORF1p: a molecular dynamics study
    Rajagopalan Muthukumaran
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Puducherry 605014, India
    Mol Biosyst 11:1987-99. 2015
  4. doi request reprint Dynamics of modeled oligonucleosomes and the role of histone variant proteins in nucleosome organization
    Amutha Ramaswamy
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Kalapet, Pondicherry, India
    Adv Protein Chem Struct Biol 90:119-49. 2013
  5. doi request reprint Structural dynamics of full-length retroviral integrase: a molecular dynamics analysis
    Sangeetha Balasubramanian
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, R V Nagar, Kalapet, Puducherry, India
    J Biomol Struct Dyn 29:659-70. 2012
  6. doi request reprint Pharmacophore based 3D-QSAR modeling and free energy analysis of VEGFR-2 inhibitors
    Muthukumaran Rajagopalan
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, R V Nagar, Kalapet, Puducherry, India
    J Enzyme Inhib Med Chem 28:1236-46. 2013

Collaborators

  • Ilya Ioshikhes
  • Ivet Bahar
  • Muthukumaran Rajagopalan
  • Sangeetha Balasubramanian
  • Rajagopalan Muthukumaran
  • Balasubramanian Sangeetha
  • Ramaswamy Amutha
  • Premendu Prakash Mathur

Detail Information

Publications6

  1. ncbi request reprint Structural dynamics of nucleosome core particle: comparison with nucleosomes containing histone variants
    Amutha Ramaswamy
    Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio 43210, USA
    Proteins 58:683-96. 2005
    ..The differences are more pronounced at the L1 and L2 loops of the respective monomers H2B and H2A, and at the N-termini of the monomers H3 and H4, all of which closely interact with the wrapping DNA...
  2. pmc Global dynamics of newly constructed oligonucleosomes of conventional and variant H2A.Z histone
    Amutha Ramaswamy
    Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA
    BMC Struct Biol 7:76. 2007
    ..Z histone variant using normal mode analysis...
  3. doi request reprint Conformational analysis on the wild type and mutated forms of human ORF1p: a molecular dynamics study
    Rajagopalan Muthukumaran
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Puducherry 605014, India
    Mol Biosyst 11:1987-99. 2015
    ..The knowledge gained from this study forms the basis for understanding the nucleic acid binding mechanism of ORF1p, which could further provide additional support in exploring various genetic disorders. ..
  4. doi request reprint Dynamics of modeled oligonucleosomes and the role of histone variant proteins in nucleosome organization
    Amutha Ramaswamy
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, Kalapet, Pondicherry, India
    Adv Protein Chem Struct Biol 90:119-49. 2013
    ..Z-H2B) dimer evidence their participation in the transcriptionally active state. The key role of variant H2A.Z histone as a major source of vibrant motions via weaker intra- and intermolecular correlations is emphasized in this chapter...
  5. doi request reprint Structural dynamics of full-length retroviral integrase: a molecular dynamics analysis
    Sangeetha Balasubramanian
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, R V Nagar, Kalapet, Puducherry, India
    J Biomol Struct Dyn 29:659-70. 2012
    ..The remaining supplementary data can be downloaded from the author's server at the URL http://ramutha.bicpu.edu.in ...
  6. doi request reprint Pharmacophore based 3D-QSAR modeling and free energy analysis of VEGFR-2 inhibitors
    Muthukumaran Rajagopalan
    Centre for Bioinformatics, School of Life Sciences, Pondicherry University, R V Nagar, Kalapet, Puducherry, India
    J Enzyme Inhib Med Chem 28:1236-46. 2013
    ..Thus, the present study proposes a pharmacophore hypothesis representing the identified interactions pattern and its further application as a template in screening databases to identify novel VEGFR-2 inhibitor scaffolds. ..