Vinagolu K Rajasekhar

Summary

Publications

  1. ncbi request reprint Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes
    Vinagolu K Rajasekhar
    Department of Surgery Neurosurgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Mol Cell 12:889-901. 2003
  2. ncbi request reprint Postgenomic global analysis of translational control induced by oncogenic signaling
    Vinagolu K Rajasekhar
    Department of Surgery Neurosurgery, Neurology, Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Oncogene 23:3248-64. 2004
  3. ncbi request reprint Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective
    Vinagolu K Rajasekhar
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Rockefeller Research Laboratories, Room 945, New York, New York 10021, USA
    Stem Cells 25:2498-510. 2007
  4. ncbi request reprint Analytical methods for cancer stem cells
    Vinagolu K Rajasekhar
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Methods Mol Biol 407:83-95. 2007
  5. ncbi request reprint Molecular insights into the function, fate, and prospects of stem cells
    Vinagolu K Rajasekhar
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Stem Cells 23:1212-20. 2005
  6. ncbi request reprint The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007
    Vinagolu K Rajasekhar
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Rockefeller Research Laboratories, New York, New York 10021, USA
    Stem Cells 26:292-8. 2008
  7. pmc Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
    Jonathan H Schatz
    Cancer Biology and Genetics Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065, USA
    J Exp Med 208:1799-807. 2011

Collaborators

Detail Information

Publications8

  1. ncbi request reprint Oncogenic Ras and Akt signaling contribute to glioblastoma formation by differential recruitment of existing mRNAs to polysomes
    Vinagolu K Rajasekhar
    Department of Surgery Neurosurgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Mol Cell 12:889-901. 2003
    ..These data support a model whereby Ras and Akt signaling primarily lead to cellular transformation by altering the transcriptome and producing a radical shift in the composition of mRNAs associated with actively translating polysomes...
  2. ncbi request reprint Postgenomic global analysis of translational control induced by oncogenic signaling
    Vinagolu K Rajasekhar
    Department of Surgery Neurosurgery, Neurology, Cancer Biology and Genetics, Memorial Sloan Kettering Cancer Center, 1275 York Ave, New York, NY 10021, USA
    Oncogene 23:3248-64. 2004
    ..To what degree this translational control is either necessary or sufficient for tumor formation or maintenance remains to be determined...
  3. ncbi request reprint Concise review: roles of polycomb group proteins in development and disease: a stem cell perspective
    Vinagolu K Rajasekhar
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Rockefeller Research Laboratories, Room 945, New York, New York 10021, USA
    Stem Cells 25:2498-510. 2007
    ..Disclosure of potential conflicts of interest is found at the end of this article...
  4. ncbi request reprint Analytical methods for cancer stem cells
    Vinagolu K Rajasekhar
    Memorial Sloan Kettering Cancer Center, New York, NY, USA
    Methods Mol Biol 407:83-95. 2007
    ..Combination of two or more of these methods for validation of cancer stem cells appears to be a promising approach for the precise isolation and analysis of cancer stem cells...
  5. ncbi request reprint Molecular insights into the function, fate, and prospects of stem cells
    Vinagolu K Rajasekhar
    Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, New York 10021, USA
    Stem Cells 23:1212-20. 2005
    ....
  6. ncbi request reprint The 5th International Society for Stem Cell Research (ISSCR) Annual Meeting, June 2007
    Vinagolu K Rajasekhar
    Memorial Sloan Kettering Cancer Center, 1275 York Avenue, Rockefeller Research Laboratories, New York, New York 10021, USA
    Stem Cells 26:292-8. 2008
    ..This hypothesis was widely explored at the conference to shed new light on the mechanisms of tumor origin and progression and to unveil novel antitumor therapeutic approaches...
  7. pmc Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
    Jonathan H Schatz
    Cancer Biology and Genetics Program, Sloan Kettering Institute for Cancer Research, New York, NY 10065, USA
    J Exp Med 208:1799-807. 2011
    ..Hence, targeting the convergence of oncogenic survival signals on translation initiation is an effective alternative to combinations of kinase inhibitors...