Shahzad Gull Raja

Summary

Publications

  1. pmc Does off-pump coronary artery bypass grafting negatively impact long-term survival and freedom from reintervention?
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Hill End Road, Harefield, London UB9 6JH, UK
    Biomed Res Int 2013:602871. 2013
  2. pmc Eritoran: the evidence of its therapeutic potential in sepsis
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Harefield Hospital, Harefield, Middlesex, UK
    Core Evid 2:199-207. 2008
  3. pmc Large patent ductus arteriosus in an adult complicated by pulmonary endarteritis and embolic lung abscess
    Manoraj Navaratnarajah
    Department of Cardiac Surgery, Harefield Hospital, Middlesex, UK
    Heart Int 6:e16. 2011
  4. ncbi Sutureless aortic valve replacement using perceval s valve
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
    Recent Pat Cardiovasc Drug Discov 8:75-80. 2013
  5. ncbi Impact of concomitant coronary artery bypass grafting on in-hospital outcome in octogenarians undergoing aortic valve replacement
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
    J Heart Valve Dis 22:177-83. 2013
  6. doi Concomitant off-pump coronary artery bypass grafting results in improved in-hospital outcomes for patients with ischemic mitral regurgitation undergoing surgery
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, UK
    Heart Surg Forum 16:E15-20. 2013
  7. doi In-hospital outcomes of pedicled bilateral internal mammary artery use in diabetic and nondiabetic patients undergoing off-pump coronary artery bypass grafting: single-surgeon, single-center experience
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, UK
    Heart Surg Forum 16:E1-7. 2013
  8. doi Impact of gentamicin-collagen sponge (Collatamp) on the incidence of sternal wound infection in high-risk cardiac surgery patients: a propensity score analysis
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, UK
    Heart Surg Forum 15:E257-61. 2012
  9. doi Local application of gentamicin-containing collagen implant in the prophylaxis and treatment of surgical site infection following cardiac surgery
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London UB9 6JH, United Kingdom
    Int J Surg 10:S10-4. 2012
  10. doi Ten-year outcome analysis of off-pump sequential grafting: single surgeon, single center experience
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
    Heart Surg Forum 15:E136-42. 2012

Collaborators

Detail Information

Publications79

  1. pmc Does off-pump coronary artery bypass grafting negatively impact long-term survival and freedom from reintervention?
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Hill End Road, Harefield, London UB9 6JH, UK
    Biomed Res Int 2013:602871. 2013
    ..93; 95% Confidence Interval 0.87-1.05). Off-pump coronary artery bypass grafting compared with on-pump coronary artery bypass grafting does not adversely impact survival or freedom from reintervention at a 10-year follow-up. ..
  2. pmc Eritoran: the evidence of its therapeutic potential in sepsis
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Harefield Hospital, Harefield, Middlesex, UK
    Core Evid 2:199-207. 2008
    ....
  3. pmc Large patent ductus arteriosus in an adult complicated by pulmonary endarteritis and embolic lung abscess
    Manoraj Navaratnarajah
    Department of Cardiac Surgery, Harefield Hospital, Middlesex, UK
    Heart Int 6:e16. 2011
    ..This brief report also provides an overview of the natural history, potential complications, optimal therapy, and diagnostic dilemmas associated with this persistent congenital cardiac defect in adults...
  4. ncbi Sutureless aortic valve replacement using perceval s valve
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
    Recent Pat Cardiovasc Drug Discov 8:75-80. 2013
    ..This article provides an overview of the published literature for Perceval S valve with an attempt to better define the role of sutureless aortic valve replacement in the treatment of critical aortic valve stenosis. ..
  5. ncbi Impact of concomitant coronary artery bypass grafting on in-hospital outcome in octogenarians undergoing aortic valve replacement
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
    J Heart Valve Dis 22:177-83. 2013
    ..Hence, a comparison was made of the impact of concomitant AVR and CABG versus isolated AVR on in-hospital outcome in octogenarians...
  6. doi Concomitant off-pump coronary artery bypass grafting results in improved in-hospital outcomes for patients with ischemic mitral regurgitation undergoing surgery
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, UK
    Heart Surg Forum 16:E15-20. 2013
    ..We hypothesize that performing off-pump coronary artery bypass (OPCAB) grafting before fixing MR improves in-hospital outcomes for patients with IMR undergoing surgery...
  7. doi In-hospital outcomes of pedicled bilateral internal mammary artery use in diabetic and nondiabetic patients undergoing off-pump coronary artery bypass grafting: single-surgeon, single-center experience
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, UK
    Heart Surg Forum 16:E1-7. 2013
    ..The purpose of this study was to compare the in-hospital outcomes of CABG using pedicled BIMA in diabetic and nondiabetic patients...
  8. doi Impact of gentamicin-collagen sponge (Collatamp) on the incidence of sternal wound infection in high-risk cardiac surgery patients: a propensity score analysis
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, UK
    Heart Surg Forum 15:E257-61. 2012
    ..The purpose of this study was to review our experience with Collatamp in cardiac surgery patients deemed at high risk for sternal wound infection...
  9. doi Local application of gentamicin-containing collagen implant in the prophylaxis and treatment of surgical site infection following cardiac surgery
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London UB9 6JH, United Kingdom
    Int J Surg 10:S10-4. 2012
    ..For the cardiac surgeon and patient the development of sternal wound infection is a serious post-operative complication associated with increased risk of death and also considerable morbidity...
  10. doi Ten-year outcome analysis of off-pump sequential grafting: single surgeon, single center experience
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
    Heart Surg Forum 15:E136-42. 2012
    ..We compared in-hospital and midterm outcomes for off-pump multivessel sequential and conventional coronary artery bypass grafting...
  11. pmc Myocardial revascularization for the elderly: current options, role of off-pump coronary artery bypass grafting and outcomes
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, United Kingdom
    Curr Cardiol Rev 8:26-36. 2012
    ....
  12. ncbi Evaluation of clinical efficacy of fasudil for the treatment of pulmonary arterial hypertension
    Shahzad G Raja
    Harefield Hospital, London, United Kingdom
    Recent Pat Cardiovasc Drug Discov 7:100-4. 2012
    ..This article provides an overview of the role of ROCK in the pathogenesis of PAH and discusses the clinical efficacy of fasudil as a therapeutic option for treating PAH...
  13. ncbi In-hospital outcomes of off-pump multivessel total arterial and conventional coronary artery bypass grafting: single surgeon, single center experience
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Harefield, United Kingdom
    Ann Thorac Surg 88:47-52. 2009
    ..We compared in-hospital outcomes for off-pump multivessel total arterial and conventional coronary artery bypass grafting...
  14. doi Impact of technique of left ventricular aneurysm repair on clinical outcomes: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, United Kingdom
    J Card Surg 24:319-24. 2009
    ..This review article attempts to evaluate the current best available evidence on the impact of technique of left ventricular aneurysm repair on postoperative clinical outcomes...
  15. doi Impact of minimal access valve surgery on clinical outcomes: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, London, UK
    J Card Surg 24:73-9. 2009
    ..This review article attempts to evaluate the current best available evidence on the impact of minimal access valve surgery on postoperative clinical outcomes...
  16. doi Surgery for functional tricuspid regurgitation: current techniques, outcomes and emerging concepts
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Middlesex, UK
    Expert Rev Cardiovasc Ther 7:73-84. 2009
    ..A better understanding of the mechanisms of functional tricuspid regurgitation will help explain the failure of current techniques and be a help to modify existing surgical techniques or develop new techniques...
  17. ncbi Quadruple valve replacement for carcinoid heart disease
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Harefield, Middlesex, United Kingdom
    J Heart Valve Dis 18:223-7. 2009
    ..The patient made an uneventful postoperative recovery, and had an excellent quality of life at the one-year follow up examination...
  18. ncbi Outcomes of off-pump coronary artery bypass surgery: current best available evidence
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Western Infirmary Glasgow, Glasgow, United Kingdom
    Indian Heart J 59:15-27. 2007
    ..This review article attempts to evaluate the current best evidence available from randomized, controlled trials in order to compare the outcomes of off-pump coronary artery bypass surgery and conventional coronary artery bypass grafting...
  19. ncbi Safety of drug eluting stents: current concerns and controversies
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Western Infirmary Glasgow, Glasgow, UK
    Curr Drug Saf 2:212-9. 2007
    ..This review article evaluates current available scientific evidence on the various safety issues related to the use of drug-eluting stents...
  20. ncbi Current status of off-pump coronary artery bypass surgery
    Shahzad G Raja
    Glasgow Royal Infirmary, Department of Cardiac Surgery Ward 65, Queen Elizabeth Building, Alexandra Parade, Glasgow, G31 2ER, Scotland United Kingdom
    Asian Cardiovasc Thorac Ann 16:164-78. 2008
    ....
  21. doi For patients undergoing coronary artery bypass grafting at higher risk of stroke is the single cross-clamp technique of benefit in reducing the incidence of stroke?
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Harefield Hospital, Hill End Road, Harefield, UB9 6JH, Middlesex, UK
    Interact Cardiovasc Thorac Surg 7:500-3. 2008
    ..MC=7/284; P=ns) although there is some advantage of SC technique in causing less neuropsychological deficits and release of serum S-100 protein, a surrogate marker of cerebral injury...
  22. doi Should angiotensin converting enzyme inhibitors/angiotensin II receptor antagonists be omitted before cardiac surgery to avoid postoperative vasodilation?
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Harefield Hospital, Hill End Road, Harefield, UB9 6JH, Middlesex, UK
    Interact Cardiovasc Thorac Surg 7:470-5. 2008
    ..However, the current available evidence to support this strategy is weak...
  23. ncbi Current status of bosentan for treatment of pulmonary hypertension
    Shahzad G Raja
    Harefield Hospital, Middlesex, United Kingdom
    Ann Card Anaesth 11:6-14. 2008
    ..This review article discusses the pharmacology of bosentan and summarises the current available evidence for the safety and efficacy of bosentan for the treatment of PAH...
  24. doi In hypoplastic left heart patients is Sano shunt compared with modified Blalock-Taussig shunt associated with deleterious effects on ventricular performance?
    Shahzad G Raja
    Department of Paediatric Cardiothoracic Surgery, Great Ormond Street Hospital, London WC1N 3JH, UK
    Interact Cardiovasc Thorac Surg 10:620-3. 2010
    ..It is expected that the Pediatric Heart Network randomised controlled trial will address this important issue...
  25. doi Endothelin receptor antagonists for pulmonary arterial hypertension: an overview
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Great Ormond Street Hospital, London, UK
    Cardiovasc Ther 28:e65-71. 2010
    ..This review attempts to provide an overview of the pharmacology, therapeutic benefits, and safety profile of ERAs in patients with PAH...
  26. ncbi Growth of pulmonary autograft after Ross operation in pediatric patients
    Shahzad G Raja
    Department of Pediatric Cardiothoracic Surgery, Alder Hey Hospital, Liverpool L12 2AP, UK
    Asian Cardiovasc Thorac Ann 12:285-90. 2004
    ..Pulmonary autograft replacement of the aortic valve appears to be the ideal solution in pediatric patients, because of relatively low operative risk, excellent late valve function, and real potential for growth...
  27. doi Fenestration closure in a calcified ventricular septal defect patch
    Shahzad G Raja
    Department of Pediatric Cardiothoracic Surgery, Great Ormond Street Hospital, London, UK
    Asian Cardiovasc Thorac Ann 19:430-2. 2011
    ..If the fenestration needs surgical closure, severe calcification of the patch may make it extremely difficult. We describe the closure of such a defect in a 6-year-old boy, using a double Dacron patch sandwich...
  28. doi Hypercoagulable state after off-pump coronary artery bypass grafting: evidence, mechanisms and implications
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Harefield, London, UB9 6JH, UK
    Expert Rev Cardiovasc Ther 9:599-608. 2011
    ....
  29. doi In cardiac surgery patients does Voluven(R) impair coagulation less than other colloids?
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Harefield, London UB9 6JH, UK
    Interact Cardiovasc Thorac Surg 12:1022-7. 2011
    ..It can be concluded that contrary to in vitro studies HES 130/0.4 in clinical practice has comparable effects on blood loss after cardiac surgery...
  30. doi Midterm follow-up of arterial switch operation for transposition of the great arteries with intact ventricular septum and left-ventricular outflow tract obstruction
    Shahzad G Raja
    Department of Paediatric Cardiothoracic Surgery, Great Ormond Street Hospital, London, WC1N 3JH, UK
    Eur J Cardiothorac Surg 40:994-9. 2011
    ....
  31. doi Surgery for carcinoid heart disease: current outcomes, concerns and controversies
    Shahzad G Raja
    Carcinoid Heart Disease Clinic, Department of Cardiology, Royal Free Hospital, London, UK
    Future Cardiol 6:647-55. 2010
    ..This article provides an overview of carcinoid heart disease with an emphasis on current outcomes, concerns and controversies associated with the surgical management of this disease...
  32. doi Basis for intervention on functional tricuspid regurgitation
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Great Ormond Street Hospital, London, United Kingdom
    Semin Thorac Cardiovasc Surg 22:79-83. 2010
    ..This review article highlights emerging concepts and advances that provide an insight into the understanding of this perplexing lesion and attempts to define the basis of intervention on functional tricuspid regurgitation...
  33. ncbi Macitentan, a tissue-targeting endothelin receptor antagonist for the potential oral treatment of pulmonary arterial hypertension and idiopathic pulmonary fibrosis
    Shahzad G Raja
    Harefield Hospital, Department of Cardiothoracic Surgery, Royal Brompton and Harefield NHS Trust, Hill End Road, Harefield, London, UB9 6JH, UK
    Curr Opin Investig Drugs 11:1066-73. 2010
    ..At the time of publication, a phase II trial in patients with IPF and a phase III trial in patients with PAH was ongoing. It is expected that the results of these trials will validate the safety and efficacy of macitentan...
  34. ncbi 10-year follow-up of off-pump multivessel coronary artery bypass grafting
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Hill End Road, Harefield, UK
    Asian Cardiovasc Thorac Ann 18:260-5. 2010
    ..At medium-term follow-up, off-pump total arterial grafting, despite being a safe and effective myocardial revascularization strategy, offered no mortality or morbidity benefits...
  35. doi Reoperative off-pump coronary artery bypass grafting: current outcomes, concerns and controversies
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Hill End Road, Harefield, London, UB9 6JH, UK
    Expert Rev Cardiovasc Ther 8:685-94. 2010
    ..This article evaluates the current outcomes of reoperative off-pump coronary artery bypass grafting, and highlights the concerns and controversies associated with this strategy...
  36. doi Right ventricle to pulmonary artery shunt modification of the Norwood procedure
    Shahzad G Raja
    Department of Paediatric Cardiothoracic Surgery, Great Ormond Street Hospital, London, WC1N 3JH, UK
    Expert Rev Cardiovasc Ther 8:675-84. 2010
    ....
  37. ncbi Impact of off-pump coronary artery bypass surgery on systemic inflammation: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Western Infirmary Glasgow, Glasgow, United Kingdom
    J Card Surg 22:445-55. 2007
    ..This review article discusses the influence of cardiopulmonary bypass on systemic inflammation and attempts to evaluate the current best available evidence on the impact of OPCAB on systemic inflammation...
  38. ncbi Delayed-onset adrenal insufficiency after cardiac surgery despite perioperative steroid supplementation
    Shahzad G Raja
    Department of Cardiothoracic Surgery, University Hospital of Wales, Cardiff, United Kingdom
    J Cardiothorac Vasc Anesth 18:80-1. 2004
  39. pmc Pump or no pump for coronary artery bypass: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Glasgow G3 8SJ, United Kingdom
    Tex Heart Inst J 32:489-501. 2005
    ..This review attempts to evaluate the best currently available evidence from clinical trials about the safety and efficacy of off-pump coronary artery bypass surgery...
  40. ncbi Drug-eluting stents: is it the beginning of the end for coronary artery bypass surgery?
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Yorkhill NHS Trust, Glasgow G3 8SJ, Scotland
    Chin Med J (Engl) 117:1377-87. 2004
  41. ncbi Impact of off-pump coronary artery bypass surgery on postoperative bleeding: current best available evidence
    Shahzad G Raja
    Royal Hospital for Sick Children, Glasgow, United Kingdom
    J Card Surg 21:35-41; discussion 42-3. 2006
    ..This review article attempts to evaluate the current best available evidence from RCTs on the impact of OPCAB on postoperative bleeding and transfusion requirements...
  42. ncbi Modulation of systemic inflammatory response after cardiac surgery
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Yorkhill NHS Trust, Dalnair Street, Glasgow G3 8SJ, Scotland, United Kingdom
    Asian Cardiovasc Thorac Ann 13:382-95. 2005
    ..This article briefly reviews the current concepts of the systemic inflammatory response following cardiac surgery, and the various therapeutic strategies being used to modulate this response...
  43. ncbi Current status of the Contegra conduit for pediatric right ventricular outflow tract reconstruction
    Shahzad G Raja
    Department of Paediatric Cardiac Surgery, Royal Hospital for Sick Children, Yorkhill NHS Trust, Glasgow, UK
    J Heart Valve Dis 14:616-22. 2005
    ..Increasingly, experience with the Contegra conduit is being published; hence, a literature search was conducted to evaluate available evidence on current use of the device in pediatric RVOT reconstruction...
  44. ncbi Outcomes after arterial switch operation for simple transposition
    Shahzad G Raja
    Department of Pediatric Cardiac Surgery, Alder Hey Hospital, Liverpool, United Kingdom
    Asian Cardiovasc Thorac Ann 13:190-8. 2005
    ..Since then ASO has become the procedure of choice in most medical centers. This review article summarizes the historical aspects of arterial switch operation and assesses this procedure's outcomes...
  45. ncbi Internal thoracic artery: to skeletonize or not to skeletonize?
    Shahzad G Raja
    Department of Cardiac Surgery, Alder Hey Hospital, Liverpool, United Kingdom
    Ann Thorac Surg 79:1805-11. 2005
    ....
  46. ncbi Total arterial myocardial revascularization: analysis of initial experience
    Shahzad Gull Raja
    Department of Cardiac Surgery, Mayo Hospital, Lahore, Pakistan
    Ann Saudi Med 25:13-7. 2005
    ..We analyze our initial experience to assess the feasibility of total arterial revascularization as a primary strategy in patients requiring first time coronary artery bypass grafting...
  47. pmc Vasoplegic syndrome after off-pump coronary artery bypass surgery: an unusual complication
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Middlesex, United Kingdom
    Tex Heart Inst J 31:421-4. 2004
    ..Herein, we discuss the pathophysiology and management of vasoplegic syndrome--which is controversial--with special emphasis on the use of vasopressin in this situation...
  48. ncbi Off-pump coronary artery bypass surgery: analysis of 5-year experience
    Shahzad G Raja
    Department of Paediatric Cardiac Surgery, Mayo Hospital, Lahore, Pakistan
    Asian Cardiovasc Thorac Ann 12:306-11. 2004
    ..5%, while the rate for the 48 patients who had previous bypass surgery was 2.1%. The results show that off-pump coronary surgery produces low mortality and morbidity, even in the treatment of multivessel disease or high-risk patients...
  49. ncbi Statins: much more than just a lipid-lowering therapy
    Shahzad G Raja
    Alder Hey Hospital, Liverpool and Harefield Hospital, Middlesex, United Kingdom
    Indian Heart J 56:204-9. 2004
  50. ncbi Body piercing: a rare cause of mitral valve endocarditis
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Harefield, Middlesex, UK
    J Heart Valve Dis 13:854-6. 2004
    ..Here, the first documented case is reported of mitral valve endocarditis in a previously fit and healthy young female following navel piercing...
  51. ncbi Sildenafil: emerging cardiovascular indications
    Shahzad G Raja
    Department of Paediatric Cardiac Surgery, Alder Hey Children s Hospital, West Derby, Liverpool, United Kingdom
    Ann Thorac Surg 78:1496-506. 2004
    ..In this review we briefly summarize the pharmacology of sildenafil and the current available evidence on its potential therapeutic applications in cardiovascular disorders...
  52. ncbi Off-pump coronary artery bypass surgery: to do or not to do? Current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Harefield Hospital, Middlesex, United Kingdom
    J Cardiothorac Vasc Anesth 18:486-505. 2004
  53. ncbi Emergency off-pump coronary artery surgery
    Shahzad G Raja
    Department of Cardiac Surgery, Alder Hey Hospital, Liverpool L12 2AP, United Kingdom
    Chin Med J (Engl) 117:823-7. 2004
    ..We present our experience to show the feasibility of off-pump coronary artery surgery as an emergency revascularization technique...
  54. pmc Ross operation in children and young adults: the Alder Hey case series
    Shahzad Gull Raja
    Department of Paediatric Cardiothoracic Surgery, Alder Hey Hospital, Eaton Road, Liverpool L12 2AP, United Kingdom
    BMC Cardiovasc Disord 4:3. 2004
    ..The purpose of this study was to review our institutional experience at Alder Hey hospital with the Ross procedure in children and young adults...
  55. ncbi Drug-eluting stents and the future of coronary artery bypass surgery: facts and fiction
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Glasgow, United Kingdom
    Ann Thorac Surg 81:1162-71. 2006
    ....
  56. ncbi Levosimendan in cardiac surgery: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Glasgow, United Kingdom
    Ann Thorac Surg 81:1536-46. 2006
    ..This review article briefly discusses the pharmacology of levosimendan and evaluates current best available evidence to assess the safety and efficacy of levosimendan usage in cardiac surgery...
  57. ncbi Should vacuum-assisted closure therapy be routinely used for management of deep sternal wound infection after cardiac surgery?
    Shahzad G Raja
    Department of Cardiothoracic Surgery Level 9, Western Infirmary Glasgow, Dumbarton Road, Glasgow, G11 6NT, UK
    Interact Cardiovasc Thorac Surg 6:523-7. 2007
    ....
  58. ncbi Moderate ischemic mitral regurgitation: to treat or not to treat?
    Shahzad G Raja
    Department of Cardiothoracic Surgery, Western Infirmary, Glasgow, United Kingdom
    J Card Surg 22:362-9. 2007
    ..This review article attempts to tackle this controversial issue and find the best approach of dealing with moderate IMR at the time of CABG by evaluating current best available evidence...
  59. ncbi Effects of escalating doses of sildenafil on hemodynamics and gas exchange in children with pulmonary hypertension and congenital cardiac defects
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Glasgow, UK
    J Cardiothorac Vasc Anesth 21:203-7. 2007
    ..The purpose of this study was to determine the effects of escalating doses of sildenafil on hemodynamics and gas exchange in children with pulmonary hypertension because of congenital cardiac defects...
  60. ncbi Impact of off-pump coronary artery bypass surgery on graft patency: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Glasgow, UK
    J Card Surg 22:165-9. 2007
    ..This review article attempts to evaluate the current best available evidence from RCTs on the impact of OPCAB surgery on graft patency...
  61. ncbi Current outcomes of Ross operation for pediatric and adolescent patients
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Yorkhill NHS Trust, Dalnair Street, Glasgow G3 8SJ, UK
    J Heart Valve Dis 16:27-36. 2007
    ..This review evaluates existing evidence on the safety and efficacy of Ross procedure for pediatric and adolescent patients...
  62. ncbi Cardioprotection with sildenafil: implications for clinical practice
    Shahzad G Raja
    MRCS Glasgow Royal Infirmary, Glasgow, UK
    Curr Med Chem 13:3155-64. 2006
    ....
  63. ncbi Contegra conduit: current outcomes and concerns
    Shahzad G Raja
    Glasgow Royal Infirmary, Department of Cardiac Surgery, Queen Elizabeth Building, Alexandra Parade, Glasgow, G31 2ER, UK
    Expert Rev Cardiovasc Ther 4:721-30. 2006
    ..This review focuses on the current outcomes of Contegra conduit and highlights some of the major concerns related to the use of this conduit and strategies to tackle these concerns...
  64. ncbi Efficacy and safety of drug-eluting stents: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Yorkhill NHS Trust, Dalnair Street, Glasgow, United Kingdom
    J Card Surg 21:605-12; discussion 613-4. 2006
    ..This review article evaluates the current best available evidence on the efficacy and safety of drug-eluting stents with a focus on the impact of this "revolutionary" new technology on the practice of coronary artery bypass surgery...
  65. ncbi Treatment of pulmonary arterial hypertension with sildenafil: from pathophysiology to clinical evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Glasgow, United Kingdom
    J Cardiothorac Vasc Anesth 20:722-35. 2006
  66. ncbi Does neoadjuvant chemotherapy improve survival in patients with resectable thoracic oesophageal cancer?
    Shahzad G Raja
    Department of Cardiothoracic Surgery Level 9, Western Infirmary Glasgow, Dumbarton Road, Glasgow, G11 6NT, UK
    Interact Cardiovasc Thorac Surg 6:661-4. 2007
    ..Benefit was less clear for squamous cell carcinoma than adenocarcinoma and the second largest randomised trial did not demonstrate a significant benefit...
  67. ncbi Pulmonary hypertension in congenital heart disease
    Shahzad G Raja
    Department of Paediatric Cardiac Surgery, Royal Hospital for Sick Children, Glasgow
    Nurs Stand 19:41-9. 2005
    ..This article reviews the pathophysiology of pulmonary hypertension due to congenital heart disease and discusses the options available for the management of this condition...
  68. ncbi Impact of modified ultrafiltration on morbidity after pediatric cardiac surgery
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Yorkhill NHS Trust, Dalnair Street, Glasgow G3 8SJ, United Kingdom
    Asian Cardiovasc Thorac Ann 14:341-50. 2006
    ..This review attempts to evaluate current available scientific evidence on the impact of modified ultrafiltration on organ function and morbidity after pediatric cardiac surgery...
  69. ncbi Impact of off-pump coronary artery bypass surgery on postoperative renal dysfunction: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Yorkhill NHS Trust, Glasgow, UK
    Nephrology (Carlton) 11:269-73. 2006
    ..The present review article attempts to evaluate the current best available evidence from randomized controlled trials on the impact of off-pump coronary artery bypass surgery on postoperative renal dysfunction...
  70. ncbi Composite arterial grafting
    Shahzad G Raja
    Glasgow Royal Infirmary, Department of Cardiothoracic Surgery Ward 65, Queen Elizabeth Building, 16 Alexandra Parade, G31 2ER, Glasgow, UK
    Expert Rev Cardiovasc Ther 4:523-33. 2006
    ....
  71. doi In young patients with rheumatic aortic regurgitation compared to non-rheumatics is a Ross operation associated with increased incidence of autograft failure?
    Shahzad G Raja
    Department of Paediatric Cardiothoracic Surgery, Great Ormond Street Hospital, London WC1N 3JH, UK
    Interact Cardiovasc Thorac Surg 10:600-4. 2010
    ..Use of pulmonary autograft in young patients (<30 years) with rheumatic aortic regurgitation and concomitant mitral regurgitation requires a cautious approach as there is an impaired autograft durability in this subgroup of patients...
  72. doi Is a flexible mitral annuloplasty ring superior to a semi-rigid or rigid ring in terms of improvement in symptoms and survival?
    Tjian Chee
    Department of Cardiothoracic Surgery, Western Infirmary, Glasgow, UK
    Interact Cardiovasc Thorac Surg 7:477-84. 2008
    ....
  73. doi For neonates undergoing cardiac surgery does thymectomy as opposed to thymic preservation have any adverse immunological consequences?
    Ahmed Afifi
    Department of Paediatric Cardiothoracic Surgery, Great Ormond Street Hospital, London WC1N 3JH, UK
    Interact Cardiovasc Thorac Surg 11:287-91. 2010
    ..Maintenance of a registry of patients undergoing neonatal thymectomy and further studies to assess the functional or clinical consequences of this practice would be valuable...
  74. ncbi Impact of stentless aortic valves on left ventricular function and hypertrophy: current best available evidence
    Shahzad G Raja
    Department of Cardiac Surgery, Royal Hospital for Sick Children, Glasgow, UK
    J Card Surg 21:313-9. 2006
    ..This review article attempts to evaluate current best available evidence from randomized controlled trials to assess the impact of stentless aortic valves on left ventricular function and hypertrophy...
  75. pmc Will off-pump coronary artery surgery replace conventional coronary artery surgery?
    Shahzad G Raja
    Department of Cardiac Surgery, Alder Hey Hospital, Liverpool L12 2AP, UK
    J R Soc Med 97:275-8. 2004
  76. doi Tricuspid leaflet augmentation to address severe tethering in functional tricuspid regurgitation
    Gilles D Dreyfus
    Department of Cardiac Surgery, Royal Brompton and Harefield NHS Trust, Harefield Hospital, Hill End Road, Harefield, Middlesex UB96JH, United Kingdom
    Eur J Cardiothorac Surg 34:908-10. 2008
    ..We describe this simple and easily reproducible technique to treat severe tricuspid regurgitation due to tethering of the tricuspid valve leaflets...
  77. ncbi Mechanism of autograft dilatation after Ross operation: some more insight please!
    Shahzad Gull Raja
    Eur J Cardiothorac Surg 28:663; author reply 663-4. 2005
  78. ncbi Management of moderate ischemic mitral regurgitation demystified
    Shahzad Gull Raja
    Eur J Cardiothorac Surg 28:778; author reply 778-9. 2005