Vittoria Rago

Summary

Publications

  1. pmc Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes
    Vittoria Rago
    Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Italy
    Reprod Biol Endocrinol 9:135. 2011
  2. ncbi Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells
    Stefania Catalano
    Centro Sanitario, University of Calabria, Arcavacata di Rende, Cosenza 87030, Italy
    J Biol Chem 279:19908-15. 2004
  3. ncbi G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    Lidia Albanito
    Departments of Pharmaco Biology and Cell Biology, University of Calabria, 87030 Rende Cosenza, Italy
    Cancer Res 67:1859-66. 2007
  4. ncbi Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells
    Marcello Maggiolini
    Department of Pharmaco Biology, University of Calabria, 87036 Rende CS, Italy
    J Mol Endocrinol 32:777-91. 2004
  5. ncbi 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30
    Adele Vivacqua
    Department of Pharmaco Biology, University of Calabria, 87030 Rende CS, Italy
    Mol Pharmacol 70:1414-23. 2006
  6. pmc Identification of ERbeta1 and ERbeta2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia
    Vittoria Rago
    Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Cosenza, Italy
    Reprod Biol Endocrinol 7:56. 2009
  7. ncbi Detection of aromatase and estrogen receptors (ERalpha, ERbeta1, ERbeta2) in human Leydig cell tumor
    Amalia Carpino
    Department of Cell Biology, University of Calabria, Arcavacata di Rende, Italy
    Eur J Endocrinol 157:239-44. 2007
  8. pmc Detection of estrogen receptors ER-alpha and ER-beta in human ejaculated immature spermatozoa with excess residual cytoplasm
    Vittoria Rago
    Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Cosenza, Italy
    Reprod Biol Endocrinol 4:36. 2006
  9. ncbi Differential expression of estrogen receptors (ERalpha/ERbeta) in testis of mature and immature pigs
    Vittoria Rago
    Department of Cell Biology, University of Calabria, 87030 Arcavacata di Rendi, Cosenza, Italy
    Anat Rec A Discov Mol Cell Evol Biol 281:1234-9. 2004
  10. doi Leptin and leptin receptor in pig spermatozoa: evidence of their involvement in sperm capacitation and survival
    Saveria Aquila
    Department of Pharmaco Biology, Faculty of Pharmacy, University of Calabria, 87036 Arcavacata di Rende, Cosenza, Italy
    Reproduction 136:23-32. 2008

Collaborators

Detail Information

Publications19

  1. pmc Identification of the estrogen receptor GPER in neoplastic and non-neoplastic human testes
    Vittoria Rago
    Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Italy
    Reprod Biol Endocrinol 9:135. 2011
    ..Recently, a G-protein-coupled-receptor (GPER) has been suggested as being involved in rapid responses to estrogens in different normal and tumor cells...
  2. ncbi Leptin induces, via ERK1/ERK2 signal, functional activation of estrogen receptor alpha in MCF-7 cells
    Stefania Catalano
    Centro Sanitario, University of Calabria, Arcavacata di Rende, Cosenza 87030, Italy
    J Biol Chem 279:19908-15. 2004
    ..Thus, we are able to demonstrate that the amplification of estrogen signal induced by leptin occurs through an enhancing in situ E(2) production as well as a direct functional activation of ERalpha...
  3. ncbi G protein-coupled receptor 30 (GPR30) mediates gene expression changes and growth response to 17beta-estradiol and selective GPR30 ligand G-1 in ovarian cancer cells
    Lidia Albanito
    Departments of Pharmaco Biology and Cell Biology, University of Calabria, 87030 Rende Cosenza, Italy
    Cancer Res 67:1859-66. 2007
    ....
  4. ncbi Oestrogen receptor beta is required for androgen-stimulated proliferation of LNCaP prostate cancer cells
    Marcello Maggiolini
    Department of Pharmaco Biology, University of Calabria, 87036 Rende CS, Italy
    J Mol Endocrinol 32:777-91. 2004
    ..Thus our findings implicate ERbeta as a potential target for the treatment of prostate tumours...
  5. ncbi 17beta-estradiol, genistein, and 4-hydroxytamoxifen induce the proliferation of thyroid cancer cells through the g protein-coupled receptor GPR30
    Adele Vivacqua
    Department of Pharmaco Biology, University of Calabria, 87030 Rende CS, Italy
    Mol Pharmacol 70:1414-23. 2006
    ..Our findings provide new insight into the molecular mechanisms through which estrogens may induce the progression of TC...
  6. pmc Identification of ERbeta1 and ERbeta2 in human seminoma, in embryonal carcinoma and in their adjacent intratubular germ cell neoplasia
    Vittoria Rago
    Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Cosenza, Italy
    Reprod Biol Endocrinol 7:56. 2009
    ..Epidemiological studies evidenced an increased incidence of testicular germ cell cancer after elevated pre-natal estrogen exposure but the expression of estrogen receptors in these testicular neoplasms has not been well elucidated...
  7. ncbi Detection of aromatase and estrogen receptors (ERalpha, ERbeta1, ERbeta2) in human Leydig cell tumor
    Amalia Carpino
    Department of Cell Biology, University of Calabria, Arcavacata di Rende, Italy
    Eur J Endocrinol 157:239-44. 2007
    ....
  8. pmc Detection of estrogen receptors ER-alpha and ER-beta in human ejaculated immature spermatozoa with excess residual cytoplasm
    Vittoria Rago
    Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Cosenza, Italy
    Reprod Biol Endocrinol 4:36. 2006
    ..The aim of this work was to investigate the expression of estrogen receptors, ER-alpha and ER-beta, in human ejaculated immature spermatozoa with excess residual cytoplasm...
  9. ncbi Differential expression of estrogen receptors (ERalpha/ERbeta) in testis of mature and immature pigs
    Vittoria Rago
    Department of Cell Biology, University of Calabria, 87030 Arcavacata di Rendi, Cosenza, Italy
    Anat Rec A Discov Mol Cell Evol Biol 281:1234-9. 2004
    ..The differential ERalpha/ERbeta expression in germ and somatic cells of the gonads suggest a role of estrogens in function and in development of pig testis...
  10. doi Leptin and leptin receptor in pig spermatozoa: evidence of their involvement in sperm capacitation and survival
    Saveria Aquila
    Department of Pharmaco Biology, Faculty of Pharmacy, University of Calabria, 87036 Arcavacata di Rende, Cosenza, Italy
    Reproduction 136:23-32. 2008
    ..The presence of leptin and its receptor in pig sperm suggests that they, through an autocrine short loop, may induce signal transduction and molecular changes associated with sperm capacitation and survival...
  11. ncbi The food contaminants bisphenol A and 4-nonylphenol act as agonists for estrogen receptor alpha in MCF7 breast cancer cells
    Adele Vivacqua
    Department of Pharmaco Biology, University of Calabria, 87036 Rende CS, Italy
    Endocrine 22:275-84. 2003
    ..The estrogenic effects of such industrial agents together with an increasing widespread human exposure should be taken into account for the potential influence also on hormone-dependent breast cancer disease...
  12. pmc Cytochrome P450arom, androgen and estrogen receptors in pig sperm
    Vittoria Rago
    Department of Cell Biology, Faculty of Pharmacy, University of Calabria, Arcavacata di Rende, Cosenza, Italy
    Reprod Biol Endocrinol 5:23. 2007
    ..The purpose of the current study was to investigate the expression of aromatase (P450arom), estrogen (ERalpha/ERbeta) and androgen (AR) receptors in ejaculated spermatozoa of pig...
  13. pmc Cytochrome P450 aromatase expression in human seminoma
    Vittoria Rago
    Cell Biology Department, Faculty of Pharmacy, University of Calabria, Italy
    Reprod Biol Endocrinol 3:72. 2005
    ..This study examined aromatase expression in human seminoma, which is the most common germ cell tumour of the testis...
  14. doi Leptin and its receptor are expressed in the testis and in the epididymis of young and adult pigs
    Vittoria Rago
    Department of Cell Biology, Faculty of Pharmacy, University of Calabria, 87036 Arcavacata di Rende, Cosenza, Italy
    Anat Rec (Hoboken) 292:736-45. 2009
    ..Therefore, our findings suggest a possible involvement of leptin in endocrine or autocrine/paracrine control of porcine male reproductive structures...
  15. pmc Inhibition of cyclooxygenase-2 down-regulates aromatase activity and decreases proliferation of Leydig tumor cells
    Rosa Sirianni
    Department of Pharmaco Biology, University of Calabria, 87036 Arcavacata di Rende CS, Italy
    J Biol Chem 284:28905-16. 2009
    ..These novel findings clarify the mechanisms involved in the growth of Leydig cell tumors and should be taken into account in determining new therapeutic approaches...
  16. ncbi Estrogenic and antiproliferative activities of isoliquiritigenin in MCF7 breast cancer cells
    Marcello Maggiolini
    Department of Pharmaco Biology, University of Calabria, 87036 Rende CS, Italy
    J Steroid Biochem Mol Biol 82:315-22. 2002
    ..Thus, the activity of ISL and the balance between risk or chemopreventive factor for estrogen-dependent breast cancer may depend on dietary intake...
  17. ncbi Evidence of aromatase localization in cytoplasmic droplet of human immature ejaculated spermatozoa
    Vittoria Rago
    Department of Cell Biology, University of Calabria, Cosenza, Italy
    Folia Histochem Cytobiol 41:23-7. 2003
    ....
  18. ncbi Towards a physiological role for cytochrome P450 aromatase in ejaculated human sperm
    Saveria Aquila
    Centro Sanitario, University of Calabria, 87030 Arcavacata di Rende, Cosenza, Italy
    Hum Reprod 18:1650-9. 2003
    ..In the present study we investigate a possible physiological role for enzymatically active P450 aromatase in human ejaculated sperm...
  19. ncbi Aromatase overexpression enhances the stimulatory effects of adrenal androgens on MCF7 breast cancer cells
    Marcello Maggiolini
    Department of Pharmaco Biology, Facolta di Farmacia, University of Calabria, I 87036 Rende, CS, Italy
    Mol Cell Endocrinol 193:13-8. 2002
    ..Our results suggest that in postmenopausal women aromatase inhibitors might be considered as an adjuvant approach to the treatment of hormone-dependent breast tumors that overexpress aromatase...