Khaled Radad

Summary

Publications

  1. doi request reprint Thymoquinone protects dopaminergic neurons against MPP+ and rotenone
    Khaled Radad
    Pathology Department, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt
    Phytother Res 23:696-700. 2009
  2. ncbi request reprint CDP-choline reduces dopaminergic cell loss induced by MPP(+) and glutamate in primary mesencephalic cell culture
    Khaled Radad
    Department of Pathology Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt
    Int J Neurosci 117:985-98. 2007
  3. ncbi request reprint Minocycline protects dopaminergic neurons against long-term rotenone toxicity
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt
    Can J Neurol Sci 37:81-5. 2010
  4. ncbi request reprint Dopaminergic neurons are preferentially sensitive to long-term rotenone toxicity in primary cell culture
    Khaled Radad
    Pathology Department, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt
    Toxicol In Vitro 22:68-74. 2008
  5. doi request reprint Vascular damage mediates neuronal and non-neuronal pathology following short and long-term rotenone administration in Sprague-Dawley rats
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt
    Exp Toxicol Pathol 65:41-7. 2013
  6. doi request reprint Ginsenosides and their CNS targets
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt
    CNS Neurosci Ther 17:761-8. 2011
  7. ncbi request reprint Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration
    Khaled Radad
    Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt
    Neurochem Int 49:379-86. 2006
  8. doi request reprint Thymoquinone ameliorates lead-induced brain damage in Sprague Dawley rats
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt Electronic address
    Exp Toxicol Pathol 66:13-7. 2014
  9. doi request reprint Recent advances in benefits and hazards of engineered nanoparticles
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt
    Environ Toxicol Pharmacol 34:661-72. 2012
  10. ncbi request reprint Use of ginseng in medicine with emphasis on neurodegenerative disorders
    Khaled Radad
    Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Assiut University, Egypt
    J Pharmacol Sci 100:175-86. 2006

Detail Information

Publications10

  1. doi request reprint Thymoquinone protects dopaminergic neurons against MPP+ and rotenone
    Khaled Radad
    Pathology Department, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt
    Phytother Res 23:696-700. 2009
    ..In conclusion, the current study presents for the first time the potential of thymoquinone to protect primary dopaminergic neurons against MPP(+) and rotenone relevant to Parkinson's disease...
  2. ncbi request reprint CDP-choline reduces dopaminergic cell loss induced by MPP(+) and glutamate in primary mesencephalic cell culture
    Khaled Radad
    Department of Pathology Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt
    Int J Neurosci 117:985-98. 2007
    ..Moreover, citicoline significantly decreased propidium iodide uptake by cultured cells. The study concludes that citicoline exerts stimulant and neuroprotective actions on cultured dopaminergic neurons...
  3. ncbi request reprint Minocycline protects dopaminergic neurons against long-term rotenone toxicity
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt
    Can J Neurol Sci 37:81-5. 2010
    ..In Parkinson's disease, most of current therapies only provide symptomatic treatment and so far there is no drug which directly affects the disease process...
  4. ncbi request reprint Dopaminergic neurons are preferentially sensitive to long-term rotenone toxicity in primary cell culture
    Khaled Radad
    Pathology Department, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt
    Toxicol In Vitro 22:68-74. 2008
    ..Other cells in the culture including non-dopaminergic neurons and glia cells appeared less affected compared to dopaminergic neurons...
  5. doi request reprint Vascular damage mediates neuronal and non-neuronal pathology following short and long-term rotenone administration in Sprague-Dawley rats
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt
    Exp Toxicol Pathol 65:41-7. 2013
    ..This effect might provide new insights for ethiopathogenesis of neurodegenerative diseases and contributes to the understanding of hemorrhagic stroke...
  6. doi request reprint Ginsenosides and their CNS targets
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt
    CNS Neurosci Ther 17:761-8. 2011
    ..In this review, we try to address the recently reported ginsenosides' actions on different CNS targets particularly those supporting possible therapeutic efficacies in CNS disorders and neurodegenerative diseases...
  7. ncbi request reprint Rotenone induces cell death in primary dopaminergic culture by increasing ROS production and inhibiting mitochondrial respiration
    Khaled Radad
    Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt
    Neurochem Int 49:379-86. 2006
    ..Rotenone exerted toxicity by decreasing the mitochondrial membrane potential, increasing reactive oxygen species production and shifting respiration to a more anaerobic state...
  8. doi request reprint Thymoquinone ameliorates lead-induced brain damage in Sprague Dawley rats
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt Electronic address
    Exp Toxicol Pathol 66:13-7. 2014
    ..Thus the current study shed some light on the beneficial effects of thymoquinone against neurotoxic effects of lead in rats. ..
  9. doi request reprint Recent advances in benefits and hazards of engineered nanoparticles
    Khaled Radad
    Department of Pathology, Faculty of Veterinary Medicine, Assiut University, Assiut 71526, Egypt
    Environ Toxicol Pharmacol 34:661-72. 2012
    ....
  10. ncbi request reprint Use of ginseng in medicine with emphasis on neurodegenerative disorders
    Khaled Radad
    Department of Pathology and Clinical Pathology, Faculty of Veterinary Medicine, Assiut University, Egypt
    J Pharmacol Sci 100:175-86. 2006
    ..In this review, we focus on recently reported medicinal effects of ginseng and summarize the current knowledge of its effects on CNS disorders and neurodegenerative diseases...