Sudeep S Gill

Summary

Affiliation: Queen's University

Publications

  1. ncbi request reprint Antipsychotic drug use and mortality in older adults with dementia
    Sudeep S Gill
    Queen s University, Kingston, Ontario, Canada
    Ann Intern Med 146:775-86. 2007
  2. ncbi request reprint A prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs
    Sudeep S Gill
    Institute for Clinical Evaluative Sciences, Toronto, Ontario
    Arch Intern Med 165:808-13. 2005
  3. pmc Atypical antipsychotic drugs and risk of ischaemic stroke: population based retrospective cohort study
    Sudeep S Gill
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, ON, Canada
    BMJ 330:445. 2005
  4. ncbi request reprint Representation of patients with dementia in clinical trials of donepezil
    Sudeep S Gill
    Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, Ontario
    Can J Clin Pharmacol 11:e274-85. 2004
  5. pmc Pharmacological treatments for neuropsychiatric symptoms of dementia in long-term care: a systematic review
    Dallas P Seitz
    Department of Psychiatry, Queen s University, Kingston, Ontario, Canada
    Int Psychogeriatr 25:185-203. 2013
  6. doi request reprint Cholinesterase inhibitors and adverse pulmonary events in older people with chronic obstructive pulmonary disease and concomitant dementia: a population-based, cohort study
    Anne Stephenson
    Women s College Research Institute, Women s College Hospital, Toronto, ON, Canada
    Drugs Aging 29:213-23. 2012
  7. doi request reprint Older men with dementia are at greater risk than women of serious events after initiating antipsychotic therapy
    Paula A Rochon
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
    J Am Geriatr Soc 61:55-61. 2013
  8. doi request reprint Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study
    Janine R Hutson
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Drugs Aging 29:205-11. 2012
  9. doi request reprint Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am J Geriatr Psychiatry 19:1026-33. 2011
  10. ncbi request reprint A population-based study of cholinesterase inhibitor use for dementia
    Nathan Herrmann
    Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Am Geriatr Soc 55:1517-23. 2007

Detail Information

Publications54

  1. ncbi request reprint Antipsychotic drug use and mortality in older adults with dementia
    Sudeep S Gill
    Queen s University, Kingston, Ontario, Canada
    Ann Intern Med 146:775-86. 2007
    ..Antipsychotic drugs are widely used to manage behavioral and psychological symptoms in dementia despite concerns about their safety...
  2. ncbi request reprint A prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs
    Sudeep S Gill
    Institute for Clinical Evaluative Sciences, Toronto, Ontario
    Arch Intern Med 165:808-13. 2005
    ..We present a new example of the prescribing cascade involving cholinesterase inhibitors and anticholinergic drugs used to manage urinary incontinence...
  3. pmc Atypical antipsychotic drugs and risk of ischaemic stroke: population based retrospective cohort study
    Sudeep S Gill
    Institute for Clinical Evaluative Sciences, 2075 Bayview Avenue, Toronto, ON, Canada
    BMJ 330:445. 2005
    ..To compare the incidence of admissions to hospital for stroke among older adults with dementia receiving atypical or typical antipsychotics...
  4. ncbi request reprint Representation of patients with dementia in clinical trials of donepezil
    Sudeep S Gill
    Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, Toronto, Ontario
    Can J Clin Pharmacol 11:e274-85. 2004
    ..To evaluate the representation of frail older adults in randomized controlled trials (RCTs), and to assess consequences of under representation by analyzing drug discontinuation rates...
  5. pmc Pharmacological treatments for neuropsychiatric symptoms of dementia in long-term care: a systematic review
    Dallas P Seitz
    Department of Psychiatry, Queen s University, Kingston, Ontario, Canada
    Int Psychogeriatr 25:185-203. 2013
    ..The objective of this study was to provide a current review of the efficacy and safety of pharmacological treatments for NPS in LTC...
  6. doi request reprint Cholinesterase inhibitors and adverse pulmonary events in older people with chronic obstructive pulmonary disease and concomitant dementia: a population-based, cohort study
    Anne Stephenson
    Women s College Research Institute, Women s College Hospital, Toronto, ON, Canada
    Drugs Aging 29:213-23. 2012
    ..Cholinesterase inhibitors (ChEIs) are a mainstay treatment for individuals with dementia. ChEIs may worsen airflow obstruction because of their pro-cholinergic properties...
  7. doi request reprint Older men with dementia are at greater risk than women of serious events after initiating antipsychotic therapy
    Paula A Rochon
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
    J Am Geriatr Soc 61:55-61. 2013
    ..To understand how drug therapy differently affects older women and men...
  8. doi request reprint Use of clarithromycin and adverse cardiovascular events among older patients receiving donepezil: a population-based, nested case-control study
    Janine R Hutson
    Faculty of Medicine, University of Toronto, Toronto, ON, Canada
    Drugs Aging 29:205-11. 2012
    ..Donepezil is metabolized by the cytochrome P450 isozyme 3A4 (CYP3A4). Clarithromycin is a potent inhibitor of CYP3A4, and patients taking both of these drugs may be at increased risk of cardiac adverse events...
  9. doi request reprint Antipsychotic drugs and the risk of hyperglycemia in older adults without diabetes: a population-based observational study
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Am J Geriatr Psychiatry 19:1026-33. 2011
    ..To determine whether current antipsychotic use among older persons without diabetes is associated with a higher risk of hospital visits for hyperglycemia, as previous studies in this population have yielded conflicting results...
  10. ncbi request reprint A population-based study of cholinesterase inhibitor use for dementia
    Nathan Herrmann
    Department of Psychiatry, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    J Am Geriatr Soc 55:1517-23. 2007
    ....
  11. doi request reprint Syncope and its consequences in patients with dementia receiving cholinesterase inhibitors: a population-based cohort study
    Sudeep S Gill
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Arch Intern Med 169:867-73. 2009
    ..These drugs can provoke symptomatic bradycardia and syncope, which may lead to permanent pacemaker insertion. Drug-induced syncope may also precipitate fall-related injuries, including hip fracture...
  12. doi request reprint Effects of cholinesterase inhibitors on postoperative outcomes of older adults with dementia undergoing hip fracture surgery
    Dallas P Seitz
    Kunin Lunenfeld Applied Research Unit, Baycrest Center, Toronto, Ontario, Canada
    Am J Geriatr Psychiatry 19:803-13. 2011
    ..We evaluated the effects of ChEIs on the postoperative outcomes of older adults who underwent hip fracture surgery...
  13. ncbi request reprint Benzodiazepine use among older adults with chronic obstructive pulmonary disease: a population-based cohort study
    Nicholas T Vozoris
    Division of Respirology, Department of Medicine, St Michael s Hospital, 30 Bond Street, Toronto, ON, M5B 1W8, Canada
    Drugs Aging 30:183-92. 2013
    ..There is minimal information on the scope and nature of benzodiazepine use in the older adult COPD population...
  14. doi request reprint The relationship between variations in antipsychotic prescribing across nursing homes and short-term mortality: quality of care implications
    Susan E Bronskill
    Institute for Clinical Evaluative Sciences, Toronto, Ontario
    Med Care 47:1000-8. 2009
    ..Determining the extent to which variations in antipsychotic use are a symptom of facility-level quality problems as compared with a drug safety issue is important for selecting the correct interventions to effect change...
  15. ncbi request reprint Demographic characteristics and healthcare use of centenarians: a population-based cohort study
    Paula A Rochon
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada Department of Medicine, University of Toronto, Toronto, Ontario, Canada Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Am Geriatr Soc 62:86-93. 2014
    ..To better understand how centenarians use the healthcare system as an important step toward improving their service delivery...
  16. doi request reprint Antipsychotics and mortality in Parkinsonism
    Connie Marras
    Morton and Gloria Shulman Movement Disorders Centre, Toronto Western Hospital, ON, Canada
    Am J Geriatr Psychiatry 20:149-58. 2012
    ..The use of antipsychotic medications is associated with an increased risk of death in older adults with dementia. The risk of death in patients with preexisting parkinsonism who receive antipsychotic drugs is not known...
  17. pmc Cholinesterase inhibitors and hospitalization for bradycardia: a population-based study
    Laura Y Park-Wyllie
    Department of Family and Community Medicine, St Michael s Hospital, Ontario, Canada
    PLoS Med 6:e1000157. 2009
    ..These drugs enhance the effects of acetylcholine, and reports suggest they may precipitate bradycardia in some patients. We aimed to examine the association between use of cholinesterase inhibitors and hospitalization for bradycardia...
  18. ncbi request reprint New thyroxine treatment in older adults beginning lithium therapy: implications for clinical practice
    Kenneth I Shulman
    Dept of Psychiatry and the Institute for Clinical Evaluative Sciences, Sunnybrook and Women s College Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario, M4N 3M5, Canada
    Am J Geriatr Psychiatry 13:299-304. 2005
    ....
  19. ncbi request reprint Antipsychotic drugs and hyperglycemia in older patients with diabetes
    Lorraine L Lipscombe
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Arch Intern Med 169:1282-9. 2009
    ..Evidence suggests that there is an association between antipsychotic drugs and new-onset diabetes, but little is known about the risk of hyperglycemia among persons with preexisting diabetes...
  20. pmc Initiation of benzodiazepines in the elderly after hospitalization
    Chaim M Bell
    Department of Medicine, St Michael s Hospital, 30 Bond Street, Toronto, Ontario, Canada, M5B 1W8
    J Gen Intern Med 22:1024-9. 2007
    ..To estimate the rate of new chronic benzodiazepine use after hospitalization in older adults not previously prescribed with benzodiazepines...
  21. doi request reprint Exploring variation in rates of polypharmacy across long term care homes
    Susan E Bronskill
    Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    J Am Med Dir Assoc 13:309.e15-21. 2012
    ..We quantified the scope of this practice by exploring variation in the use of nine or more drug therapies across LTC homes...
  22. doi request reprint Inhaled anticholinergic drug therapy and the risk of acute urinary retention in chronic obstructive pulmonary disease: a population-based study
    Anne Stephenson
    Department of Medicine, Keenan Research Centre, Li Ka Shing Knowledge Institute of St Michael s Hospital, Toronto, ON, Canada
    Arch Intern Med 171:914-20. 2011
    ..The systemic anticholinergic effects of IAC therapy have not been extensively studied. This study sought to determine the risk of acute urinary retention (AUR) in seniors with COPD using IACs...
  23. pmc Effects of impairment in activities of daily living on predicting mortality following hip fracture surgery in studies using administrative healthcare databases
    Dallas P Seitz
    Department of Psychiatry, Queen s University, Kingston, Ontario, Canada
    BMC Geriatr 14:9. 2014
    ..We evaluated the impact of ADL function on predicting postoperative mortality among older adults with hip fractures in Ontario, Canada...
  24. doi request reprint Risk of perioperative blood transfusions and postoperative complications associated with serotonergic antidepressants in older adults undergoing hip fracture surgery
    Dallas P Seitz
    From the Division of Geriatric Psychiatry, Department of Psychiatry, Queen s University, Kingston Mount Sinai Hospital Institute for Clinical Evaluative Sciences Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto Department of Medicine, Institute for Clinical Evaluative Sciences, Department of Anesthesia and Perioperative Medicine, Queen s University, Kingston Department of Psychiatry, Sunnybrook Health Sciences Centre and University of Toronto and Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
    J Clin Psychopharmacol 33:790-8. 2013
    ..Clinicians should be aware of this increased risk, although routine discontinuation of antidepressants before surgery is likely unwarranted in most cases. ..
  25. pmc The timing of drug funding announcements relative to elections: a case study involving dementia medications
    Sudeep S Gill
    Department of Medicine, Queen s University, Kingston, Ontario, Canada
    PLoS ONE 8:e56921. 2013
    ..We examined the temporal relationship between decisions to add one class of drugs to publicly funded formularies in Canada's ten provinces and elections in these jurisdictions...
  26. pmc Approach to inappropriate sexual behaviour in people with dementia
    Petra Joller
    Queen s University, Kingston, ON, Canada
    Can Fam Physician 59:255-60. 2013
    ..To provide family physicians with an update on the approach to diagnosis and management of inappropriate sexual behaviour (ISB) in persons with dementia...
  27. doi request reprint Systemic effects of intravitreal vascular endothelial growth factor inhibitors
    Robert J Campbell
    Department of Ophthalmology, Queen s University, Kingston, Ontario, Canada
    Curr Opin Ophthalmol 24:197-204. 2013
    ..However, VEGF functions in many physiological and pathological processes. Consequently, inhibition of this signalling molecule carries the potential to cause serious adverse events...
  28. doi request reprint Stroke rates after introduction of vascular endothelial growth factor inhibitors for macular degeneration: a time series analysis
    Robert J Campbell
    Department of Ophthalmology, Queen s University, Kingston, Canada
    Ophthalmology 119:1604-8. 2012
    ..To assess whether stroke rates among patients with retinal disease were influenced by the rapid and sequential uptakes of bevacizumab and ranibizumab for age-related macular degeneration (AMD)...
  29. doi request reprint Prevalence of dementia and cognitive impairment among older adults with hip fractures
    Dallas P Seitz
    Department of Psychiatry, Providence Care Mental Health Services, Division of Geriatric Psychiatry, Queen s University, Kingston, Ontario, Canada
    J Am Med Dir Assoc 12:556-64. 2011
    ..Little is known of the prevalence of dementia and cognitive impairment among older adults with hip fractures...
  30. ncbi request reprint Nursing home profit status and quality of care: is there any evidence of an association?
    Michael P Hillmer
    University of Toronto, Toronto, Ontario, Canada
    Med Care Res Rev 62:139-66. 2005
    ..For-profit nursing homes appear to provide lower quality of care in many important areas of process and outcome...
  31. ncbi request reprint Potentially inappropriate prescribing in Ontario community-dwelling older adults and nursing home residents
    Christopher J Lane
    Department of Medicine, University of Toronto, Toronto, Canada
    J Am Geriatr Soc 52:861-6. 2004
    ..To compare patterns of potentially inappropriate drug therapy prescribing in community-dwelling older adults and nursing home residents in Ontario, Canada...
  32. pmc Atypical antipsychotic drugs in the treatment of behavioural and psychological symptoms of dementia: systematic review
    Philip E Lee
    Rotman Research Institute, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, ON, Canada M6A 2E1
    BMJ 329:75. 2004
    ..To review the role of oral atypical antipsychotic drugs in the management of the behavioural and psychological symptoms of dementia (BPSD)...
  33. doi request reprint Association between tamsulosin and serious ophthalmic adverse events in older men following cataract surgery
    Chaim M Bell
    Institute for Clinical Evaluative Sciences, Toronto, ON, Canada
    JAMA 301:1991-6. 2009
    ..No studies have documented whether use of tamsulosin or other alpha-blocker drug therapies affect the risk of serious postoperative adverse events...
  34. pmc Gender differences in home care clients and admission to long-term care in Ontario, Canada: a population-based retrospective cohort study
    Andrea Gruneir
    Women s College Research Institute, Women s College Hospital, Toronto, Ontario, Canada
    BMC Geriatr 13:48. 2013
    ..Our objectives were to quantify differences between women and men who used home care in Ontario, Canada and to determine if there were subsequent differences in LTC admission...
  35. ncbi request reprint Clinic-based glaucoma care in the era of surgical subspecialization
    Robert J Campbell
    Department of Ophthalmology, Queen s University, Kingston, Ontario, Canada Department of Ophthalmology, Hotel Dieu and Kingston General Hospitals, Kingston, Ontario, Canada Institute for Clinical Evaluative Sciences Queen s University Site, Queen s University, Kingston, Ontario, Canada Electronic address
    Am J Ophthalmol 157:631-639.e2. 2014
    ..To evaluate the impact of surgeon practice profile on clinic-based glaucoma care...
  36. doi request reprint Efficacy and feasibility of nonpharmacological interventions for neuropsychiatric symptoms of dementia in long term care: a systematic review
    Dallas P Seitz
    Department of Psychiatry, Queen s University, Kingston, Ontario, Canada
    J Am Med Dir Assoc 13:503-506.e2. 2012
    ....
  37. pmc Adverse events with intravitreal injection of vascular endothelial growth factor inhibitors: nested case-control study
    Robert J Campbell
    Department of Ophthalmology, Queen s University, Kingston, ON, Canada
    BMJ 345:e4203. 2012
    ..To assess the risk of systemic adverse events associated with intravitreal injections of vascular endothelial growth factor inhibiting drugs...
  38. ncbi request reprint Antidepressants for agitation and psychosis in dementia
    Dallas P Seitz
    Department of Psychiatry, Queen s University, 752 King Street West, Kingston, Ontario, Canada, K7L 4X3
    Cochrane Database Syst Rev 2:CD008191. 2011
    ..Agitation and psychosis are common among older adults with dementia and are challenging to manage. At the present time, little is known about the efficacy and safety of antidepressant medications when used to treat these symptoms...
  39. doi request reprint Neuroleptic malignant syndrome complicating antipsychotic treatment of delirium or agitation in medical and surgical patients: case reports and a review of the literature
    Dallas P Seitz
    Department of Psychiatry, Queen s University, Kingston, Ontario, Canada
    Psychosomatics 50:8-15. 2009
    ..Neuroleptic malignant syndrome (NMS) is a potentially fatal adverse event associated with the use of antipsychotics...
  40. ncbi request reprint Preventing pressure ulcers: a systematic review
    Madhuri Reddy
    Division of Geriatric Medicine, Department of Medicine, University of Toronto, Toronto, Ontario
    JAMA 296:974-84. 2006
    ..Pressure ulcers are common in a variety of patient settings and are associated with adverse health outcomes and high treatment costs...
  41. ncbi request reprint Antipsychotics in the treatment of delirium: a systematic review
    Dallas P Seitz
    Department of Psychiatry, Queen s University, Kingston, Ontario, Canada
    J Clin Psychiatry 68:11-21. 2007
    ..The purpose of this study was to systematically evaluate the evidence for the efficacy and safety of antipsychotics in treating delirium...
  42. doi request reprint Body mass index, coronary artery calcification, and kidney function decline in stage 3 to 5 chronic kidney disease patients
    Jocelyn S Garland
    Division of Nephrology, Department of Medicine, Queen s University, Kingston, Ontario, Canada
    J Ren Nutr 23:4-11. 2013
    ..To determine whether body mass index (BMI) and coronary artery calcification (CAC) are risk factors for kidney function decline in predialysis chronic kidney disease (CKD) patients...
  43. ncbi request reprint The value of positron emission tomography in the clinical evaluation of dementia
    Sudeep S Gill
    Kunin Lunenfeld Applied Research Unit, Baycrest Center for Geriatric Care, Toronto, Canada
    J Am Geriatr Soc 51:258-64. 2003
    ..In conclusion, there is little evidence to support the addition of PET to the routine clinical evaluation of patients with suspected or established dementia. Suggestions for future research in this area are offered...
  44. ncbi request reprint Haunted manuscripts: ghost authorship in the medical literature
    Stephanie Ngai
    Kunin Lunenfeld Applied Research Unit, Baycrest Centre for Geriatric Care, 3560 Bathurst Street, Toronto, Ontario, M6A 2E1, Canada
    Account Res 12:103-14. 2005
    ..Other approaches have been taken by the United Kingdom and Denmark. A solution is necessary, as the relationship between authorship and accountability must be maintained...
  45. doi request reprint Citalopram versus other antidepressants for late-life depression: a systematic review and meta-analysis
    Dallas P Seitz
    Department of Psychiatry, Baycrest Centre, Toronto, Ontario, Canada
    Int J Geriatr Psychiatry 25:1296-305. 2010
    ..To determine the efficacy and tolerability of citalopram when compared to other antidepressants for late-life depression (LLD)...
  46. ncbi request reprint Antipsychotic medications and drug-induced movement disorders other than parkinsonism: a population-based cohort study in older adults
    Philip E Lee
    Division of Geriatric Medicine, Providence Health Care, University of British Columbia, St Paul s Hospital, Vancouver, British Columbia, Canada
    J Am Geriatr Soc 53:1374-9. 2005
    ..To study the relationship between initiating therapy with an antipsychotic medication and a subsequent new diagnosis of a drug-induced movement disorder other than parkinsonism in older adults with dementia...
  47. doi request reprint Antipsychotic therapy and short-term serious events in older adults with dementia
    Paula A Rochon
    Department of Medicine, University of Toronto, Canada
    Arch Intern Med 168:1090-6. 2008
    ....
  48. ncbi request reprint Skilled nursing facility rehabilitation and discharge to home after stroke
    Walter P Wodchis
    Toronto Rehabilitation Institute Toronto, ON Canada
    Arch Phys Med Rehabil 86:442-8. 2005
    ..To determine the relation between rehabilitation therapy (RT) intensity and time to discharge home for stroke patients in skilled nursing facilities (SNFs)...
  49. ncbi request reprint Association of antipsychotics with mortality among elderly patients with dementia
    Sudeep S Gill
    Am J Geriatr Psychiatry 15:983-4; author reply 984-5. 2007
  50. pmc Effect of regulatory warnings on antipsychotic prescription rates among elderly patients with dementia: a population-based time-series analysis
    Elmira Valiyeva
    The Department of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ont
    CMAJ 179:438-46. 2008
    ..We assessed the impact of these warnings on prescription rates of antipsychotic drugs in this patient population...
  51. ncbi request reprint Atypical antipsychotic drugs, dementia, and risk of death
    Sudeep S Gill
    JAMA 295:495-6; author reply 496-7. 2006
  52. ncbi request reprint Management of overactive bladder
    Sudeep S Gill
    N Engl J Med 350:2213. 2004
  53. ncbi request reprint Delusions and hallucinations in Alzheimer disease
    Sudeep S Gill
    Arch Neurol 63:627; author reply 627. 2006
  54. ncbi request reprint Perioperative haloperidol to prevent postoperative delirium
    Dallas Seitz
    J Am Geriatr Soc 54:861; author reply 861-3. 2006