- High-throughput functional genomic methods to analyze the effects of dietary lipids
Laszlo G Puskas
Laboratory for Functional Genomics, Biological Research Center of the Hungarian Academy of Sciences, Temesvari krt 62 Szeged, H 6726, Hungary
Curr Pharm Biotechnol 7:525-9. 2006
..Other results will also be mentioned obtained from cholesterol and polyunsaturated fatty acid fed animals by using DNA- and protein microarrays...
- Metabolic syndrome influences cardiac gene expression pattern at the transcript level in male ZDF rats
Cardiovascular Research Group, Department of Biochemistry, Faculty of Medicine, University of Szeged, Szeged, Hungary
Cardiovasc Diabetol 12:16. 2013
..Therefore, we examined the possible alterations in cardiac gene expression pattern in male Zucker Diabetic Fatty (ZDF) rats, a model of metabolic syndrome...
- Transgenic fat-1 mouse as a model to study the pathophysiology of cardiovascular, neurological and psychiatric disorders
Undurti N Das
Jawaharlal Nehru Technological University, Kakinada 533 003, Andhra Pradesh, India
Lipids Health Dis 8:61. 2009
..Identifying the anti-inflammatory compounds from n-3 fatty acids that suppress low-grade systemic inflammatory conditions and understanding their mechanism(s) of action may lead to newer therapeutic strategies...
- MicroRNA profile of polyunsaturated fatty acid treated glioma cells reveal apoptosis-specific expression changes
Functional Genomics Laboratory, Biological Research Center of the Hungarian Academy of Sciences, Szeged, Hungary
Lipids Health Dis 10:173. 2011
..Polyunsaturated fatty acids (PUFAs) such as γ-linolenic acid (GLA), arachidonic acid (AA) and docosahexaenoic acid (DHA) have cytotoxic action on glioma cells...
- Gene and protein expression profiling of the fat-1 mouse brain
Functional Genomics Laboratory, Biological Research Center of the Hungarian Academy of Sciences, Temesvari krt 62, Szeged H 6726, Hungary
Prostaglandins Leukot Essent Fatty Acids 80:33-42. 2009
..Based on these data, it is evident that n-3 PUFAs act to modulate specific genes and formation of their protein products and thus, bring about their various beneficial actions...
- Nutrigenomic approaches to study the effects of n-3 PUFA diet in the central nervous system
Laszlo G Puskas
Laboratory for Functional Genomics, Biological Research Center Hungarian Academy of Sciences, P O Box 521, Szeged, H 6701, Hungary
Nutr Health 18:227-32. 2006
- Toxicogenomics screening of small molecules using high-density, nanocapillary real-time PCR
Laboratory of Functional Genomics, Biological Research Center of the Hungarian Academy of Sciences, 6726 Szeged, Hungary
Int J Mol Med 23:65-74. 2009
- Gene and protein expression changes in response to normoxic perfusion in mouse hearts
Laboratory of Functional Genomics, Biological Research Center, Hungarian Academy of Sciences, H 6726, Szeged, Hungary
J Pharmacol Toxicol Methods 57:145-54. 2008
..Therefore, here we investigated the time-dependent effect of normoxic, normothermic perfusion on global gene expression at mRNA and protein levels...
- Kalman filtering for disease-state estimation from microarray data
János Z Kelemen
Laboratory of Functional Genomics, Biological Research Centre, Hungarian Academy of Sciences, Szeged Temesvári krt 62, H 6726, Hungary
Bioinformatics 22:3047-53. 2006
- Aromatic sulfonamides containing a condensed piperidine moiety as potential oxidative stress-inducing anticancer agents
AVIDIN Ltd Alsó kikötö sor 11, Szeged, H 6726, Hungary
Med Chem 9:911-9. 2013