Mean platelet volume is increased in chronic hepatitis C patients with advanced fibrosisTugrul Purnak
Department of Gastroenterology, Ankara Numune Education and Research Hospital, Ankara, Turkey
Clin Res Hepatol Gastroenterol 37:41-6. 2013
..The goal of the present study was to evaluate whether MPV would be useful in predicting liver histologic severity in CHC...
- The involvement of nitric oxide in the physiopathology of hepatoportal sclerosis
Tugrul Purnak
MD, Department of Gastroenterology Ankara Numune Education and Research Hospital, Ankara, Turkey
Clin Biochem 45:1450-4. 2012
..Although there is no data in literature that depicts the role of NO in HPS pathogenesis, this study was conducted in order to evaluate the potential role of NO in patients with HPS...
The evaluation of bone mineral density in patients with nonalcoholic fatty liver diseaseTugrul Purnak
Department of Gastroenterology, Ankara Numune Education and Research Hospital, Talatpasa Bulvari, Samanpazari, 06100, Ankara, Turkey
Wien Klin Wochenschr 124:526-31. 2012
..Inflammation is a known risk factor for low bone mass in the body. The primary goal of the present study was to evaluate the association between bone mineral density and liver function in patients with NASH...
- Serum angiotensin-converting enzyme level as a marker of fibrosis in patients with chronic hepatitis B
Tugrul Purnak
Department of Gastroenterology, Ankara Numune Education and Research Hospital, Ankara, Turkey
J Renin Angiotensin Aldosterone Syst 13:244-9. 2012
..Moreover the association between liver fibrosis and serum ACE levels was also investigated...
Mean platelet volume could be a promising biomarker to monitor dietary compliance in celiac diseaseTugrul Purnak
Department of Gastroenterology, Ankara Numune Education and Research Hospital, Samanpazari, Sihhiye Ankara, Turkey
Ups J Med Sci 116:208-11. 2011
..The elimination of gluten from the diet is the main therapeutic approach and usually leads to clinical and laboratory improvement. There are no ideal markers that objectively assess dietary compliance in CD patients...
- Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper
Tugrul Purnak
Numune Education and Research Hospital, Department of Gastroenterology, Ankara, Turkey
Phytother Res 25:312-3. 2011
..Here we report a challenging upper GI bleeding case with a low platelet count and defective hemostasis treated endoscopically with ABS as an adjunctive drug. Copyright © 2010 John Wiley & Sons, Ltd...
- Mean platelet volume as an indicator of disease severity in patients with acute pancreatitis
Yavuz Beyazit
Department of Gastroenterology, Turkiye Yuksek Ihtisas Education and Research Hospital, Sihhiye, 06100, Ankara, Turkey
Clin Res Hepatol Gastroenterol 36:162-8. 2012
..Additionally possible relationship of MPV with clinical and radiologic parameters in conjunction with other inflammatory markers during AP was also investigated...
- Can red cell distribution width help to discriminate benign from malignant biliary obstruction? A retrospective single center analysis
Yavuz Beyazit
Department of Gastroenterology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
Hepatogastroenterology 59:1469-73. 2012
..The aim of this study is to evaluate the usefulness of red cell distribution width (RDW) in differentiating benign and malignant causes of obstructive jaundice...
- Serum adenosine deaminase activity as a predictor of disease severity in ulcerative colitis
Yavuz Beyazit
Department of Gastroenterology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
J Crohns Colitis 6:102-7. 2012
..Although ADA has been shown to increase in several inflammatory conditions, there are no literature data indicating an alteration in UC...
- Recent insights into the relationship between inflammatory liver diseases and atherosclerosis
Tugrul Purnak
Department of Gastroenterology, Ankara Numune Education and Research Hospital, Ankara, Turkey
J Investig Med 59:904-11. 2011
..In this review, the most commonly encountered inflammatory liver diseases and their effects on atherosclerosis are discussed...
- Elevated levels of circulating angiotensin converting enzyme in patients with hepatoportal sclerosis
Yavuz Beyazit
Department of Gastroenterology, Turkiye Yuksek Ihtisas Education and Research Hospital, Sihhiye, 06100, Ankara, Turkey
Dig Dis Sci 56:2160-5. 2011
..The aim of the present study was to investigate the possible role of the ACE in the context of RAS in HPS pathogenesis...
- Serum nitric oxide levels in patients with benign and malignant biliary disease: a prospective single center study
Yavuz Beyazit
Department of Gastroenterology, Turkiye Yuksek Ihtisas Education and Research Hospital, Ankara, Turkey
J Clin Gastroenterol 47:258-63. 2013
....
- Increased ACE in extrahepatic cholangiocarcinoma as a clue for activated RAS in biliary neoplasms
Yavuz Beyazit
Department of Gastroenterology, Turkiye Yuksek Ihtisas Education and Research Hospital, Sihhiye, 06100 Ankara, Turkey
Clin Res Hepatol Gastroenterol 35:644-9. 2011
..In the present study, we aimed to analyze the relationship between the levels of circulating angiotensin converting enzyme (ACE), an important molecule of the renin-angiotensin system (RAS), and biliary disorders...
- Autoimmune hepatitis/primary biliary cirrhosis overlap syndrome and associated extrahepatic autoimmune diseases
Cumali Efe
Department of Gastroenterology, Numune Research and Education Hospital, Ankara, Turkey
Eur J Gastroenterol Hepatol 24:531-4. 2012
..To assess the prevalence of concurrent extrahepatic autoimmune diseases in patients with autoimmune hepatitis (AIH)/primary biliary cirrhosis (PBC) overlap syndrome and applicability of the 'mosaic of autoimmunity' in these patients...
- Antibodies to soluble liver antigen in patients with various liver diseases: a multicentre study
Cumali Efe
Department of Gastroenterology, Numune Research and Education Hospital, Ankara, Turkey
Liver Int 33:190-6. 2013
..To retrospectively assess the estimated prevalence, sensitivity, specificity and clinical significance of anti-SLA in AIH and various liver diseases...
- Autoimmune liver disease in patients with systemic lupus erythematosus: a retrospective analysis of 147 cases
Cumali Efe
Department of Internal Medicine, Ankara Numune Research and Education Hospital, Ankara, Turkey
Scand J Gastroenterol 46:732-7. 2011
..We also evaluated the accuracy of diagnostic criteria and scoring systems for AILD in SLE...
- Diagnostic difficulties, therapeutic strategies, and performance of scoring systems in patients with autoimmune hepatitis and concurrent hepatitis B/C
Cumali Efe
Department of Gastroenterology, Hacettepe University, Ankara, Turkey
Scand J Gastroenterol 48:504-8. 2013
..To date, only a few case-based studies have described this association...
- Liver biopsy is a superior diagnostic method in some patients showing the typical laboratory features of autoimmune hepatitis
Cumali Efe
Department of Gastroenterology, Hacettepe University Faculty of Medicine, Ankara, Turkey
Clin Res Hepatol Gastroenterol 36:185-8. 2012
..To investigate whether liver diseases other than autoimmune hepatitis (AIH) can present with the typical features of AIH, and to determine the impact of liver biopsy for differentiating AIH from these conditions...
- A new candidate as a hemostatic agent for difficult situations during variceal bleeding: Ankaferd blood stopper
Ersan Ozaslan
Department of Gastroenterology, Numune Education and Research Hospital, Ankara, Turkey
Saudi J Gastroenterol 17:145-8. 2011
..ABS seems to be effective in cases of variceal bleeding as a bridge to therapy. Its major advantages are the ease of use and lack of side-effects...
- Liver fibrosis may reduce the efficacy of budesonide in the treatment of autoimmune hepatitis and overlap syndrome
Cumali Efe
Department of Gastroenterology, Hacettepe University Faculty of Medicine, Ankara, Turkey
Autoimmun Rev 11:330-4. 2012
..The aim of the present study was to assess the efficacy and tolerability of budesonide as an alternative first line treatment option for autoimmune hepatitis (AIH) and the overlap syndrome...
- [Evaluation of treatment results among patients with acute gastrointestinal bleeding due to Dieulafoy's lesion admitted to the emergency department]
Yavuz Beyazit
Department of Gastroenterology, Turkiye Yuksek Ihtisas Training and Research Hospital, Ankara, Turkey
Ulus Travma Acil Cerrahi Derg 19:133-9. 2013
..In the present study, we aimed to review the clinical experience with DL in our center, primarily focusing on clinical features and endoscopic therapeutic preferences according to clinical outcomes...
- Alterations in the 'local umbilical cord blood renin-angiotensin system' during pre-eclampsia
Kadir Acar
Department of Hematology, Zekai Tahir Burak Women s Health and Research Hospital, Ankara, Turkey
Acta Obstet Gynecol Scand 86:1193-9. 2007
..The aim of this study is to search alterations of the local umbilical cord RAS during pre-eclampsia...
- Therapy response and outcome of overlap syndromes: autoimmune hepatitis and primary biliary cirrhosis compared to autoimmune hepatitis and autoimmune cholangitis
Ersan Ozaslan
Numune Education and Research Hospital, Department of Gastroenterology, Ankara, Turkey
Hepatogastroenterology 57:441-6. 2010
..We have assessed two different overlap syndrome groups in patients with AIH-PBC and AIH-AIC, with respect to therapy response and outcome...
- Autoimmune hepatitis in the postpartum period
Cumali Efe
Department of Gastroenterology, Numune Research and Education Hospital, Yazgan sokak 21 12 Cebeci, Ankara, Turkey
Clin Res Hepatol Gastroenterol 36:391-3. 2012
..Autoimmune hepatitis (AIH) presenting primarily in the postpartum period has rarely been reported...
- A comparison of Jurkat cell-reactive anti-T lymphocyte globulin and fetal anti-thymocyte globulin preparations in the treatment of aplastic anemia
Songul Serefhanoglu
Department of Internal Medicine, Division of Hematology, Hacettepe University Hospital, Ankara, Turkey
Med Princ Pract 20:341-4. 2011
..The aim of this study was to investigate the success rate and effects on survival of different anti-thymocyte globulin (ATG) preparations in patients diagnosed with aplastic anemia...
- Local bone marrow Renin-Angiotensin system and atherosclerosis
Yavuz Beyazit
Department of Gastroenterology, Turkiye Yuksek Ihtisas Teaching and Research Hospital, 06100 Ankara, Turkey
Cardiol Res Pract 2011:714515. 2010
..The aim of this paper is to review the function of local BM RAS in the pathogenesis of atherosclerosis...
- Bleeding due to slippage of elastic band during variceal ligation: successful use of Ankaferd blood stopper
Ersan Ozaslan
Department of Gastroenterology, Numune Education and Research Hospital, Ankara, Turkey
Indian J Gastroenterol 29:166-8. 2010
..The major advantages of ABS appear to be ease of use and lack of side effect...
