Tomas Pulido

Summary

Affiliation: Ignacio Chavez National Heart Institute
Location: Mexico City, Mexico
Summary:
Internal Medicine Residency - UNAM, Mexico City
Respiratory Medicine - University of Manitoba
Professor of Medicine, La Salle University Faculty of Medicine, Mexico City
Head, Cardiopulmonary Department at the Ignacio Chavez National Heart Institute in Mexico.
Involved in clinical research of diseases of the pulmonary circulation including pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension, congenital heart disease and pulmonary embolism.

Publications

  1. ncbi request reprint Bosentan therapy for pulmonary arterial hypertension
    Lewis J Rubin
    Division of Pulmonary and Critical Care Medicine, University of California at San Diego, La Jolla 92037 1330, USA
    N Engl J Med 346:896-903. 2002
  2. doi request reprint Macitentan and morbidity and mortality in pulmonary arterial hypertension
    Tomas Pulido
    Cardiopulmonary Department, Ignacio Chávez National Heart Institute, Mexico City, Mexico
    N Engl J Med 369:809-18. 2013
  3. ncbi request reprint Left and right ventricular power: outputs are the strongest hemodynamic correlates to allow identification of acute responders to vasodilator treatment in idiopathic pulmonary arterial hypertension
    Eulo Lupi-Herrera
    Sub Direction of Clinical Research
    Arch Cardiol Mex 81:100-7. 2011
  4. doi request reprint Safety and efficacy of sitaxsentan 50 and 100 mg in patients with pulmonary arterial hypertension
    Julio Sandoval
    National Heart Institute, Mexico City, Mexico
    Pulm Pharmacol Ther 25:33-9. 2012
  5. doi request reprint A randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertension
    Robyn J Barst
    Columbia University, New York, NY, USA
    Circulation 125:324-34. 2012
  6. doi request reprint Does anticoagulation in Eisenmenger syndrome impact long-term survival?
    Julio Sandoval
    Cardiopulmonary Department, Ignacio Chavez National Institute of Cardiology, Mexico City, Mexico
    Congenit Heart Dis 7:268-76. 2012
  7. ncbi request reprint [Management of acute pulmonary thromboembolism]
    Tomás Pulido-Zamudio
    Departamento de Cardioneumologia, Instituto Nacional de Cardiologia Ignacio Chavez
    Arch Cardiol Mex 82:48-53. 2012
  8. doi request reprint Efficacy and safety of oral treprostinil monotherapy for the treatment of pulmonary arterial hypertension: a randomized, controlled trial
    Zhi Cheng Jing
    Shanghai Pulmonary Hospital, Tongji University School of Medicine, No 507 Zhengmin Rd, Yangpu District, Shanghai, China 20043
    Circulation 127:624-33. 2013
  9. doi request reprint Pharmacokinetics of oral treprostinil sustained release tablets during chronic administration to patients with pulmonary arterial hypertension
    R James White
    Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY 14623, USA
    J Cardiovasc Pharmacol 61:474-81. 2013
  10. ncbi request reprint [Capillary blood gas test usefulness to evaluate gas exchange with 21% and 100% of oxygen inspired fractions in subjects with stable cardiopulmonary disease at 2,240 meters above sea level]
    Luis Efrén Santos-Martínez
    Departamento de Cardioneumologia, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, Mexico D F, Mexico
    Arch Cardiol Mex 79:18-26. 2009

Collaborators

Detail Information

Publications24

  1. ncbi request reprint Bosentan therapy for pulmonary arterial hypertension
    Lewis J Rubin
    Division of Pulmonary and Critical Care Medicine, University of California at San Diego, La Jolla 92037 1330, USA
    N Engl J Med 346:896-903. 2002
    ..The present trial investigated the effect of bosentan on exercise capacity in a larger number of patients and compared two doses...
  2. doi request reprint Macitentan and morbidity and mortality in pulmonary arterial hypertension
    Tomas Pulido
    Cardiopulmonary Department, Ignacio Chávez National Heart Institute, Mexico City, Mexico
    N Engl J Med 369:809-18. 2013
    ..We assessed the efficacy of macitentan, a new dual endothelin-receptor antagonist, using a primary end point of morbidity and mortality in a long-term trial...
  3. ncbi request reprint Left and right ventricular power: outputs are the strongest hemodynamic correlates to allow identification of acute responders to vasodilator treatment in idiopathic pulmonary arterial hypertension
    Eulo Lupi-Herrera
    Sub Direction of Clinical Research
    Arch Cardiol Mex 81:100-7. 2011
    ....
  4. doi request reprint Safety and efficacy of sitaxsentan 50 and 100 mg in patients with pulmonary arterial hypertension
    Julio Sandoval
    National Heart Institute, Mexico City, Mexico
    Pulm Pharmacol Ther 25:33-9. 2012
    ..To assess safety and efficacy of sitaxsentan 50 and 100 mg in patients with pulmonary arterial hypertension (PAH)...
  5. doi request reprint A randomized, double-blind, placebo-controlled, dose-ranging study of oral sildenafil citrate in treatment-naive children with pulmonary arterial hypertension
    Robyn J Barst
    Columbia University, New York, NY, USA
    Circulation 125:324-34. 2012
    ..Safe, effective therapy is needed for pediatric pulmonary arterial hypertension...
  6. doi request reprint Does anticoagulation in Eisenmenger syndrome impact long-term survival?
    Julio Sandoval
    Cardiopulmonary Department, Ignacio Chavez National Institute of Cardiology, Mexico City, Mexico
    Congenit Heart Dis 7:268-76. 2012
    ..To determine the impact of anticoagulation on survival in Eisenmenger syndrome...
  7. ncbi request reprint [Management of acute pulmonary thromboembolism]
    Tomás Pulido-Zamudio
    Departamento de Cardioneumologia, Instituto Nacional de Cardiologia Ignacio Chavez
    Arch Cardiol Mex 82:48-53. 2012
    ..Pulmonary embolism management includes hemodynamic support, anticoagulation, thrombolysis and embolectomy. We present an overview of the treatment of APE...
  8. doi request reprint Efficacy and safety of oral treprostinil monotherapy for the treatment of pulmonary arterial hypertension: a randomized, controlled trial
    Zhi Cheng Jing
    Shanghai Pulmonary Hospital, Tongji University School of Medicine, No 507 Zhengmin Rd, Yangpu District, Shanghai, China 20043
    Circulation 127:624-33. 2013
    ..This study was designed to evaluate the safety and efficacy of the oral prostacyclin analogue treprostinil diolamine as initial treatment for de novo PAH...
  9. doi request reprint Pharmacokinetics of oral treprostinil sustained release tablets during chronic administration to patients with pulmonary arterial hypertension
    R James White
    Division of Pulmonary and Critical Care Medicine, University of Rochester, Rochester, NY 14623, USA
    J Cardiovasc Pharmacol 61:474-81. 2013
    ..We conclude that twice-daily oral treprostinil provides sustained and proportional treprostinil concentrations over a wide range of doses during chronic administration to PAH patients...
  10. ncbi request reprint [Capillary blood gas test usefulness to evaluate gas exchange with 21% and 100% of oxygen inspired fractions in subjects with stable cardiopulmonary disease at 2,240 meters above sea level]
    Luis Efrén Santos-Martínez
    Departamento de Cardioneumologia, Instituto Nacional de Cardiologia Ignacio Chavez, Tlalpan, Mexico D F, Mexico
    Arch Cardiol Mex 79:18-26. 2009
    ..In order to know the degree of agreement between these gases, we evaluate them at breathing room air and at 100% of oxygen fractions at 2,240 meters above sea level...
  11. ncbi request reprint [Impact of the deep breathing maneuver in the gas exchange in the subject with severe obesity and pulmonary arterial hypertension associated to Eisenmenger's syndrome]
    Luis Efrén Santos-Martínez
    Departamento de Cardioneumologia, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, D F
    Arch Cardiol Mex 78:265-72. 2008
    ..In severe obese patients with the Eisenmenger's syndrome, this correlation is unknown...
  12. ncbi request reprint [Pharmacological treatment of pulmonary arterial hypertension]
    Tomás Pulido Zamudio
    Departamento de Cardioneumologia, Instituto Nacional de Cardiologia Ignacio Chavez, INCICH, Juan Badiano Núm 1 4o piso, Col Seccion XVI, Tlalpan 14080, Mexico, DF
    Arch Cardiol Mex 77:S4-198-201. 2007
    ..Despite these advances, pulmonary arterial hypertension remains an incurable disease, so the focus of new studies is the combination of two or more drugs with a different mechanism of action...
  13. ncbi request reprint [What is new in the treatment of pulmonary artery hypertension?]
    Tomás Pulido Zamudio
    Departamento de Cardioneumologia, Instituto Nacional de Cardiologia Ignacio Chavez, INCICH, Juan Badiano No 1 4 to Piso, Col Seccion XVI, Tlalpan, 14080 Mexico D F
    Arch Cardiol Mex 73:S121-4. 2003
    ..As long as research continues to scrutinize the pathogenesis of this disease, clues to possible new therapies are warranted...
  14. ncbi request reprint [Severe right ventricular hypertension secondary to metastatic obstruction due to hepatocarcinoma]
    Luis Efrén Santos Martínez
    Departamento de Cardioneumologia, Instituto Nacional de Cardiologia, Ignacio Chavez, Tlalpan, Mexico
    Arch Cardiol Mex 75:170-7. 2005
    ..The studies did not demonstrate neoplastic activity at any other level...
  15. ncbi request reprint [Massive pulmonary embolism, thrombus in transit, and right ventricular dysfunction]
    Luis Efrén Santos Martínez
    Departamento de Cardioneumologí, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano Núm 1 Col Sección XVI, Tlalpan 14080, DF Mexico
    Arch Cardiol Mex 77:44-53. 2007
    ..There was an immediate hemodynamic improvement and the post-thrombolysis angiography performed after 24-h demonstrated an improvement of the pulmonary circulation as well as decreased pulmonary artery pressures...
  16. ncbi request reprint [Modification of a hydraulic device for controlled banding of the trunk of the pulmonary artery in dogs]
    Luis Efrén Santos Martínez
    Instituto Nacional de Cardiologia Ignacio Chavez, Departamento de Cardioneumologia, INCICH Juan Badiano No 1, Col Seccion XVI, Tlalpan 14080, Mexico DF
    Arch Cardiol Mex 75:S3-10-20. 2005
    ..The elevation is achieved by pulmonary artery banding with linen tape or hydraulic devices. We introduce a new hydraulic device to be used in experimental subjects of less than 15 kilograms...
  17. ncbi request reprint [Clinical implications and prognostic significance of the study on the circadian variation of heart rate variability in patients with severe pulmonary hypertension]
    Martin Rosas-Peralta
    Departamento de Investigación Cardiopulmonar, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, DF Mexico
    Gac Med Mex 142:19-28. 2006
    ....
  18. ncbi request reprint Effects of the oral endothelin-receptor antagonist bosentan on echocardiographic and doppler measures in patients with pulmonary arterial hypertension
    Nazzareno Galie
    Institute of Cardiology, University of Bologna, Italy
    J Am Coll Cardiol 41:1380-6. 2003
    ..The purpose of this study was to investigate the effects of bosentan (125 or 250 mg twice daily) on echocardiographic and Doppler variables in 85 patients with World Health Organization class III or IV pulmonary arterial hypertension (PAH)...
  19. ncbi request reprint Pulmonary embolism as a cause of death in patients with heart disease: an autopsy study
    Tomas Pulido
    Cardiopulmonary, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico D F, Mexico
    Chest 129:1282-7. 2006
    ..To establish the prevalence of pulmonary embolism (PE) in autopsy material at a tertiary cardiac referral center and its importance as a cause of death in patients with heart disease (HD)...
  20. ncbi request reprint The role of pulmonary pressure/cardiac index to identify pulmonary hemodynamic responders to acute oxygen breathing pulmonary hypertension COPD patients
    Eulo Lupi-Herrera
    Sub Direction of Clinical Investigation
    Arch Cardiol Mex 81:208-16. 2011
    ..5%) in pulmonary hypertension (PH) - COPD patients...
  21. ncbi request reprint [Medical reflections on a case of pulmonary thromboembolism in pregnancy]
    Luis Efrén Santos-Martínez
    Circulación Pulmonar, UMAE Hospital de Cardiología Centro Médico Nacional Siglo XXI, IMSS Cuidados Intensivos Posoperatorios Cardiovasculares del Instituto Nacional de Cardiología, Ignacio Chavez
    Arch Cardiol Mex 80:255-60. 2010
    ..Appropriate therapy allowed maternal and fetal survival...
  22. ncbi request reprint [Pressure-flow relationships interpretation in idiopathic pulmonary arterial hypertension]
    Eulo Lupi-Herrera
    Sub Dirección de Investigación Clínica Instituto Nacional de Cardiología Ignacio Chávez
    Arch Cardiol Mex 80:163-73. 2010
    ..We analyze exercise-derived mean pulmonary artery pressure/cardiac index relationship to expand the concepts regarding its nature and to better identify "responders" in idiopathic pulmonary arterial hypertension patients...
  23. doi request reprint Combined clot fragmentation and aspiration in patients with acute pulmonary embolism
    Guering Eid-Lidt
    Department of Interventional Cardiology, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano No 1, Tlalpan, CP 14080, Mexico City, Mexico
    Chest 134:54-60. 2008
    ..We describe our experience using PMT in patients with massive PE and RVD with unsuccessful thrombolysis, increased bleeding risk, or major contraindications for thrombolytic therapy...
  24. ncbi request reprint [Clinical interpretation for the pressure-flow relationships in extrinsic allergic alveolitis and in interstitial lung disease pulmonary hypertension patients. Should we care for the lung, the pulmonary artery pressure or both?]
    Eulo Lupi-Herrera
    Subdirección de Investigación Clínica, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico, D F Mexico
    Arch Cardiol Mex 79:91-103. 2009
    ..5%) and to hydralazine (H) in extrinsic allergic alveolitis (EAA) and chronic interstitial lung disease (CILD) pulmonary hypertension (PH) patients...