Future directions in research, treatment and prevention of HPV-related squamous cell carcinoma of the head and neckAmanda Psyrri
2nd Department of Internal Medicine, Attikon Hospital, National Kapodistrian University of Athens, 12462 Athens, Greece
Head Neck Pathol 6:S121-8. 2012
..This review summarizes the main events of HPV-induced carcinogenesis with an emphasis on the implications of these carcinogenic mechanisms on research, treatment and prevention of HPV-associated OSCC...
- Strategies to promote translational research within the European Organisation for Research and Treatment of Cancer (EORTC) Head and Neck Cancer Group: a report from the Translational Research Subcommittee
A Psyrri
Second Department of Internal Medicine, Propaedeutic, University of Athens Medical School, Attikon University Hospital, Athens, Greece
Ann Oncol 21:1952-60. 2010
..In the present report, we summarize our strategic plans to promote head and neck cancer research within the EORTC framework...
Human papillomavirus-related head and neck tumors: clinical and research implicationAmanda Psyrri
Second Department of Internal Medicine, Attikon University Hospital, Athens, Greece
Curr Opin Oncol 21:201-5. 2009
..The demonstration that HPV is causally associated with a subset of HNSCC has tremendous clinical and research implications...
Carboplatin/gemcitabine alternating with carboplatin/pegylated liposomal doxorubicin and carboplatin/cyclophosphamide in platinum-refractory/resistant paclitaxel - pretreated ovarian carcinomaD Pectasides
Second Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, University General Hospital Attikon, Rimini 1, Haidari, Athens, Greece
Gynecol Oncol 118:52-7. 2010
..In this phase II study the efficacy and toxicity of an alternating chemotherapy regimen was examined in platinum-resistant relapsed epithelial ovarian cancer (EOC) patients...
- Prognostic significance of UBE2C mRNA expression in high-risk early breast cancer. A Hellenic Cooperative Oncology Group (HeCOG) Study
A Psyrri
Second Department of Internal Medicine, Attikon University Hospital, Athens
Ann Oncol 23:1422-7. 2012
..In the present study, we sought to explore the prognostic and/or predictive significance of UBE2C messenger RNA (mRNA) expression on disease-free survival (DFS) and overall survival (OS) in high-risk operable breast cancer patients...
- Gastric metastases originating from breast cancer: report of 8 cases and review of the literature
D Pectasides
Second Department of Internal Medicine, Attikon University Hospital, Rimini 1, Haidari, Athens, Greece
Anticancer Res 29:4759-63. 2009
....
- Prospective, open-label, randomized, phase III study of two dose-dense regimens MVAC versus gemcitabine/cisplatin in patients with inoperable, metastatic or relapsed urothelial cancer: a Hellenic Cooperative Oncology Group study (HE 16/03)
A Bamias
Department of Clinical Therapeutics, Alexandra Hospital, Athens University Medical School, Athens, Greece
Ann Oncol 24:1011-7. 2013
..However, the role of GC intensification has not been studied. We conducted a randomized, phase III study comparing a DD-GC regimen with DD-MVAC in advanced UC...
- Radiotherapy for Hodgkin's lymphoma: too hard to die?
A G Zygogianni
Iaso Private Hospital, Radiotherapy Department, Athens, Greece
J BUON 17:116-23. 2012
..Analysis of randomized studies supports the inclusion of reduced-field and dose of RT in the radiotherapeutic treatment options for HL. RT is an integral part of the combined-modality therapy (CMT) of HL...
- Optimizing approaches to head-and-neck cancers. Viruses in head-and-neck cancers: prevention and therapy
A Psyrri
Second Department of Internal Medicine, Attikon University Hospital, Athens, Greece
Ann Oncol 19:vii189-94. 2008
- Testicular function in poor-risk nonseminomatous germ cell tumors treated with methotrexate, paclitaxel, ifosfamide, and cisplatin combination chemotherapy
D Pectasides
Second Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Rimini 1, Haidari, Athens, Greece
J Androl 30:280-6. 2009
..The majority of men with poor-risk germ cell tumors who were treated with the M-TIP regimen demonstrated recovery spermatogenesis after treatment, and Leydig cell function was unaffected...
- Carboplatin and paclitaxel in metastatic or recurrent cervical cancer
Dimitrios Pectasides
2nd Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Athens, Greece
Int J Gynecol Cancer 19:777-81. 2009
..The purpose of this study was to evaluate the activity and toxicity of carboplatin and paclitaxel combination in advanced or recurrent carcinoma of the cervix...
- Hybrid capture vs. PCR screening of cervical human papilloma virus infections. Cytological and histological associations in 1270 women
Sotirios Tsiodras
Department of Cytopathology, Attikon University Hospital, University of Athens Med, Sch, Athens, Greece
BMC Cancer 10:53. 2010
..We evaluated two molecular methods of HPV detection and their correlation with cytological and histological diagnosis in a large sample of Greek women...
- Gemcitabine and pegylated liposomal doxorubicin alternating with cisplatin plus cyclophosphamide in platinum refractory/resistant, paclitaxel-pretreated, ovarian carcinoma
Dimitrios Pectasides
2nd Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Haidari, 1 Rimini, Athens, Greece
Gynecol Oncol 108:47-52. 2008
....
- Combination chemotherapy with docetaxel, vinorelbine and estramustine phosphate in metastatic androgen-resistant prostate cancer: a single institution experience
Dimitrios Pectasides
Second Department of Internal Medicine, Propaedeutic, Oncology Section, University of Athens, Attikon University Hospital, Haidari, Athens, Greece
Anticancer Res 29:769-75. 2009
..The aim of this study was to evaluate the activity and toxicity of docetaxel, vinorelbine and oral estramustine in androgen-resistant prostate cancer (ARPC)...
- Loss of tumour suppressor p16 expression in initial stages of oral oncogenesis
Eleftherios Vairaktaris
Department of Oral and Maxillofacial Surgery, University of Athens Medical School, Vas Sofias 93 and Dim Soutsou 1, Athens 11521, Greece
Anticancer Res 27:979-84. 2007
..p16 expression in sequential histological stages of oral squamous cell carcinoma (OSCC) formation was investigated using an experimental model of induced oral carcinogenesis in Syrian golden hamsters...
- Treatment issues in clear cell carcinoma of the ovary: a different entity?
Dimitrios Pectasides
Second Department of Internal Medicine, Oncology Section, University of Athens, Greece
Oncologist 11:1089-94. 2006
..Our goal was to review the clinical features and management of patients with OCCC...
- Activation of Wnt signaling pathway by human papillomavirus E6 and E7 oncogenes in HPV16-positive oropharyngeal squamous carcinoma cells
Theodore Rampias
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
Mol Cancer Res 8:433-43. 2010
..In addition, we show the significance of the endogenous Siah-1-dependent ubiquitin/proteasome pathway for beta-catenin degradation and its regulation by E6/E7 viral oncoproteins in HPV16-positive oropharyngeal cancer cells...
