Colin C Pritchard

Summary

Publications

  1. pmc Plasma processing conditions substantially influence circulating microRNA biomarker levels
    Heather H Cheng
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 8:e64795. 2013
  2. pmc Validation and implementation of targeted capture and sequencing for the detection of actionable mutation, copy number variation, and gene rearrangement in clinical cancer specimens
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, Washington Electronic address
    J Mol Diagn 16:56-67. 2014
  3. pmc ColoSeq provides comprehensive lynch and polyposis syndrome mutational analysis using massively parallel sequencing
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA
    J Mol Diagn 14:357-66. 2012
  4. pmc COLD-PCR enhanced melting curve analysis improves diagnostic accuracy for KRAS mutations in colorectal carcinoma
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, USA
    BMC Clin Pathol 10:6. 2010
  5. ncbi request reprint MicroRNA profiling: approaches and considerations
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Nat Rev Genet 13:358-69. 2012
  6. doi request reprint A mosaic PTEN mutation causing Cowden syndrome identified by deep sequencing
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Genet Med 15:1004-7. 2013
  7. pmc Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation
    Joseph B Hiatt
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA
    Genome Res 23:843-54. 2013
  8. doi request reprint Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Cancer Prev Res (Phila) 5:492-7. 2012

Collaborators

Detail Information

Publications8

  1. pmc Plasma processing conditions substantially influence circulating microRNA biomarker levels
    Heather H Cheng
    Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 8:e64795. 2013
    ..We provide specific practical recommendations to help minimize confounding variation attributable to plasma processing and platelet contamination...
  2. pmc Validation and implementation of targeted capture and sequencing for the detection of actionable mutation, copy number variation, and gene rearrangement in clinical cancer specimens
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, Washington Electronic address
    J Mol Diagn 16:56-67. 2014
    ..To best guide existing and emerging treatment regimens and facilitate integration of genomic testing with patient care, we developed a framework for data analysis, decision support, and reporting clinically actionable results...
  3. pmc ColoSeq provides comprehensive lynch and polyposis syndrome mutational analysis using massively parallel sequencing
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, 1959 NE Pacific St, Seattle, WA 98195, USA
    J Mol Diagn 14:357-66. 2012
    ..ColoSeq offers a powerful, cost-effective means of genetic testing for Lynch and polyposis syndromes that eliminates the need for stepwise testing and multiple follow-up clinical visits...
  4. pmc COLD-PCR enhanced melting curve analysis improves diagnostic accuracy for KRAS mutations in colorectal carcinoma
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, USA
    BMC Clin Pathol 10:6. 2010
    ..Many laboratories have implemented sensitive tests for KRAS mutations, but the methods often require expensive instrumentation and reagents, parallel reactions, multiple steps, or opening PCR tubes...
  5. ncbi request reprint MicroRNA profiling: approaches and considerations
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Nat Rev Genet 13:358-69. 2012
    ..Here, we review the major considerations for carrying out and interpreting results of miRNA-profiling studies...
  6. doi request reprint A mosaic PTEN mutation causing Cowden syndrome identified by deep sequencing
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Genet Med 15:1004-7. 2013
    ..We report a 40-year-old woman with a clinical diagnosis of Cowden syndrome including Lhermitte-Duclos disease, who had a mosaic PTEN mutation detected by next-generation deep sequencing...
  7. pmc Single molecule molecular inversion probes for targeted, high-accuracy detection of low-frequency variation
    Joseph B Hiatt
    Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA
    Genome Res 23:843-54. 2013
    ..3%-1.4%), and NRAS p.Q61R (colon, 4.7%). We anticipate that smMIP will be broadly adoptable as a practical and effective method for accurately detecting low-frequency mutations in both research and clinical settings...
  8. doi request reprint Blood cell origin of circulating microRNAs: a cautionary note for cancer biomarker studies
    Colin C Pritchard
    Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA
    Cancer Prev Res (Phila) 5:492-7. 2012
    ....