Gregor A Prindull

Summary

Publications

  1. ncbi request reprint Epigenetic mismatches with mutated transcribing genes at leukemogenic S-phase binding/start sites--potential targets for therapy with enzyme inhibitors
    Gregor Prindull
    Department Pediatrics, University of Gottingen, Germany
    Curr Stem Cell Res Ther 7:420-9. 2012
  2. ncbi request reprint Hypothesis: cell plasticity, linking embryonal stem cells to adult stem cell reservoirs and metastatic cancer cells?
    Gregor Prindull
    Department of Pediatrics, University of Gottingen Medical School, Germany
    Exp Hematol 33:738-46. 2005
  3. ncbi request reprint Hemangioblasts representing a functional endothelio-hematopoietic entity in ontogeny, postnatal life, and CML neovasculogenesis
    Gregor Prindull
    Pediatric Hematology Oncology, University of Gottingen, Germany
    Stem Cell Rev 1:277-84. 2005
  4. ncbi request reprint Are postnatal hemangioblasts generated by dedifferentiation from committed hematopoietic stem cells?
    Gregor A Prindull
    Department of Pediatrics, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Exp Hematol 35:691-701. 2007
  5. doi request reprint Final checkup of neoplastic DNA replication: evidence for failure in decision-making at the mitotic cell cycle checkpoint G(1)/S
    Gregor Prindull
    Department of Pediatrics, University of Gottingen, Gottingen, Germany
    Exp Hematol 36:1403-16. 2008

Detail Information

Publications5

  1. ncbi request reprint Epigenetic mismatches with mutated transcribing genes at leukemogenic S-phase binding/start sites--potential targets for therapy with enzyme inhibitors
    Gregor Prindull
    Department Pediatrics, University of Gottingen, Germany
    Curr Stem Cell Res Ther 7:420-9. 2012
    ..During transport by sliding nucleosomes, reprogrammed leukemogenic TFs are misplaced at transcription factor binding-/starting-sites (TFBS /TSS) allowing them to interact with and trigger replication of mutated leukemic genes...
  2. ncbi request reprint Hypothesis: cell plasticity, linking embryonal stem cells to adult stem cell reservoirs and metastatic cancer cells?
    Gregor Prindull
    Department of Pediatrics, University of Gottingen Medical School, Germany
    Exp Hematol 33:738-46. 2005
    ..Furthermore, EMT could possibly serve as a conceptional link between physiologic and pathologic signaling pathways. Clonal confirmation in humans is necessary...
  3. ncbi request reprint Hemangioblasts representing a functional endothelio-hematopoietic entity in ontogeny, postnatal life, and CML neovasculogenesis
    Gregor Prindull
    Pediatric Hematology Oncology, University of Gottingen, Germany
    Stem Cell Rev 1:277-84. 2005
    ..The relation of the other leukemias to hemangioblasts is not known...
  4. ncbi request reprint Are postnatal hemangioblasts generated by dedifferentiation from committed hematopoietic stem cells?
    Gregor A Prindull
    Department of Pediatrics, University of Gottingen, Robert Koch Strasse 40, 37075 Gottingen, Germany
    Exp Hematol 35:691-701. 2007
    ..Here, we review the molecular mechanisms of cell dedifferentiation and suggest for hematopoietic development that postnatal hemangioblasts are generated by dedifferentiation of committed hematopoietic stem cells...
  5. doi request reprint Final checkup of neoplastic DNA replication: evidence for failure in decision-making at the mitotic cell cycle checkpoint G(1)/S
    Gregor Prindull
    Department of Pediatrics, University of Gottingen, Gottingen, Germany
    Exp Hematol 36:1403-16. 2008
    ..e., switches from proliferation to cycle arrest and neoplastic transformation). Further analyses of cycle progression will open up new approaches in antineoplastic therapy...