Jos Prickaerts

Summary

Publications

  1. doi request reprint EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors
    Jos Prickaerts
    Maastricht University, School for Mental Health and Neuroscience, 6200 MD Maastricht, The Netherlands
    Neuropharmacology 62:1099-110. 2012
  2. pmc Differential BDNF responses of triple versus dual reuptake inhibition in neuronal and astrocytoma cells as well as in rat hippocampus and prefrontal cortex
    Jos Prickaerts
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
    J Mol Neurosci 48:167-75. 2012
  3. doi request reprint Acute tryptophan depletion in C57BL/6 mice does not induce central serotonin reduction or affective behavioural changes
    Eva L Van Donkelaar
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Neurochem Int 56:21-34. 2010
  4. doi request reprint Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion
    Eva L Van Donkelaar
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Eur J Pharmacol 600:98-104. 2008
  5. doi request reprint Object recognition testing: rodent species, strains, housing conditions, and estrous cycle
    Nick P van Goethem
    Department of Psychiatry and Neuropsychology, School for Mental Health and NeuroScience MHeNS, European Graduate School of Neuroscience EURON, Maastricht University, Maastricht, The Netherlands
    Behav Brain Res 232:323-34. 2012
  6. doi request reprint Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801
    Olga A H Reneerkens
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Behav Brain Res 236:16-22. 2013
  7. doi request reprint Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease
    Annerieke S R Sierksma
    Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Science, School for Mental Health and NeuroScience MHeNS, Maastricht University, Maastricht, The Netherlands
    Neuropharmacology 64:124-36. 2013
  8. pmc Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice
    Tim Vanmierlo
    Department of Neuroscience, Maastricht University, Universiteitssingel 50, 6229, ER, Maastricht, The Netherlands
    Plant Foods Hum Nutr 66:149-56. 2011
  9. doi request reprint Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice
    Annerieke S R Sierksma
    School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Neurobiol Aging 34:319-37. 2013
  10. doi request reprint Stress-mediated decreases in brain-derived neurotrophic factor as potential confounding factor for acute tryptophan depletion-induced neurochemical effects
    Eva L Van Donkelaar
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, 6200 MD Maastricht, The Netherlands
    Eur Neuropsychopharmacol 19:812-21. 2009

Collaborators

Detail Information

Publications47

  1. doi request reprint EVP-6124, a novel and selective α7 nicotinic acetylcholine receptor partial agonist, improves memory performance by potentiating the acetylcholine response of α7 nicotinic acetylcholine receptors
    Jos Prickaerts
    Maastricht University, School for Mental Health and Neuroscience, 6200 MD Maastricht, The Netherlands
    Neuropharmacology 62:1099-110. 2012
    ..This article is part of a Special Issue entitled 'Post-Traumatic Stress Disorder'...
  2. pmc Differential BDNF responses of triple versus dual reuptake inhibition in neuronal and astrocytoma cells as well as in rat hippocampus and prefrontal cortex
    Jos Prickaerts
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
    J Mol Neurosci 48:167-75. 2012
    ....
  3. doi request reprint Acute tryptophan depletion in C57BL/6 mice does not induce central serotonin reduction or affective behavioural changes
    Eva L Van Donkelaar
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Neurochem Int 56:21-34. 2010
    ..Although in healthy mice no clear central serotonin or functional effects were observed, further research is indicated using mice with pre-existing serotonin dysfunction, as they might be more vulnerable to acute tryptophan depletion...
  4. doi request reprint Phosphodiesterase 2 and 5 inhibition attenuates the object memory deficit induced by acute tryptophan depletion
    Eva L Van Donkelaar
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Eur J Pharmacol 600:98-104. 2008
    ....
  5. doi request reprint Object recognition testing: rodent species, strains, housing conditions, and estrous cycle
    Nick P van Goethem
    Department of Psychiatry and Neuropsychology, School for Mental Health and NeuroScience MHeNS, European Graduate School of Neuroscience EURON, Maastricht University, Maastricht, The Netherlands
    Behav Brain Res 232:323-34. 2012
    ..Thus, rodent species, strain, housing, and estrous cycle should be taken into consideration in ORT studies...
  6. doi request reprint Inhibition of phoshodiesterase type 2 or type 10 reverses object memory deficits induced by scopolamine or MK-801
    Olga A H Reneerkens
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Behav Brain Res 236:16-22. 2013
    ..We concluded that since BAY 60-7550 and PQ10 reversed both scopolamine- and MK-801-induced memory deficits, this supports the notion that dual substrate PDE inhibitors might be suitable candidates for cognition enhancement...
  7. doi request reprint Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease
    Annerieke S R Sierksma
    Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Science, School for Mental Health and NeuroScience MHeNS, Maastricht University, Maastricht, The Netherlands
    Neuropharmacology 64:124-36. 2013
    ..This article is part of a Special Issue entitled 'Cognitive Enhancers'...
  8. pmc Cerebral accumulation of dietary derivable plant sterols does not interfere with memory and anxiety related behavior in Abcg5-/- mice
    Tim Vanmierlo
    Department of Neuroscience, Maastricht University, Universiteitssingel 50, 6229, ER, Maastricht, The Netherlands
    Plant Foods Hum Nutr 66:149-56. 2011
    ..Thus, our data provide no contra-indication for nutritional intake of plant sterol enriched nutrition...
  9. doi request reprint Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice
    Annerieke S R Sierksma
    School for Mental Health and Neuroscience, Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Neurobiol Aging 34:319-37. 2013
    ..Moreover, given the remarkable sex differences observed, one should not overlook the impact of sex-specific responses to environmental exposures when investigating gene-environment interactions in AD...
  10. doi request reprint Stress-mediated decreases in brain-derived neurotrophic factor as potential confounding factor for acute tryptophan depletion-induced neurochemical effects
    Eva L Van Donkelaar
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, 6200 MD Maastricht, The Netherlands
    Eur Neuropsychopharmacol 19:812-21. 2009
    ..Thus, BDNF-mediated mechanisms due to ATD and/or its application stress might underlie ATD-induced neurochemical and behavioural alterations...
  11. doi request reprint Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in adult male Wistar rats
    Eva L Van Donkelaar
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    J Neurosci Res 88:1557-68. 2010
    ....
  12. ncbi request reprint Dissociable effects of acetylcholinesterase inhibitors and phosphodiesterase type 5 inhibitors on object recognition memory: acquisition versus consolidation
    Jos Prickaerts
    Department of Psychiatry and Neuropsychology, Brain and Behavior Institute, Maastricht University, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Psychopharmacology (Berl) 177:381-90. 2005
    ..Phosphodiesterase enzyme type 5 (PDE5) inhibitors and acetylcholinesterase (AChE) inhibitors have cognition-enhancing properties. However, it is not known whether these drug classes affect the same memory processes...
  13. doi request reprint Fetal asphyctic preconditioning protects against perinatal asphyxia-induced behavioral consequences in adulthood
    Eveline Strackx
    School for Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, European Graduate School of Neuroscience EURON, Maastricht, The Netherlands
    Behav Brain Res 208:343-51. 2010
    ..Therefore, this model seems to offer good opportunities for the identification and characterization of the underlying mechanisms of preconditioning...
  14. ncbi request reprint Prenatal stress reduces S100B in the neonatal rat hippocampus
    Daniel L A van den Hove
    Department of Pediatrics, Faculty of Medicine, Maastricht University, Maastricht, The Netherlands
    Neuroreport 17:1077-80. 2006
    ..In conclusion, the observed reduction in neonatal hippocampal S100B levels, as a consequence of prenatal stress, may be involved in affecting postnatal brain development...
  15. ncbi request reprint Maternal stress-induced reduction in birth weight as a marker for adult affective state
    Daniel L A van den Hove
    Department of Neuroscience, School for Mental Health and Neuroscience, Maastricht University, European Graduate School of Neuroscience, Universiteitssingel 50, PO Box 616, 6200 MD, Maastricht, The Netherlands
    Front Biosci (Elite Ed) 2:43-6. 2010
    ..Female birth weight did not correlate to any of the studied outcome measures. These data suggest that male birth weight may represent a valuable indicative marker for variations in adult affective state with a developmental origin...
  16. ncbi request reprint Time-dependent involvement of cAMP and cGMP in consolidation of object memory: studies using selective phosphodiesterase type 2, 4 and 5 inhibitors
    Kris Rutten
    Department of Psychiatry and Neuropsychology, Brain and Behavior Institute, EURON, Maastricht University, 6200 MD Maastricht, The Netherlands
    Eur J Pharmacol 558:107-12. 2007
    ..Moreover, the present study provides further support that selective PDE-Is can influence memory consolidation in a time-dependent manner, assumingly by elevating central cAMP and cGMP levels...
  17. pmc Fluoxetine during development reverses the effects of prenatal stress on depressive-like behavior and hippocampal neurogenesis in adolescence
    Ine Rayen
    Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    PLoS ONE 6:e24003. 2011
    ..This research provides important evidence on the long-term effect of fluoxetine exposure during development in a model of maternal adversity...
  18. doi request reprint Fetal asphyxia leads to a decrease in dorsal raphe serotonergic neurons
    Eveline Strackx
    School of Mental Health and Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Dev Neurosci 30:358-66. 2008
    ..These results support the notion that insults caused by asphyxiation during critical periods of brain development could create a predisposition to serotonergic abnormalities and anxiety deficits in adulthood...
  19. doi request reprint Memory deficits in the transgenic rat model of Huntington's disease
    Dagmar H Zeef
    Department of Neuroscience, Maastricht University, Maastricht, The Netherlands
    Behav Brain Res 227:194-8. 2012
    ..Since HD patients are known to be impaired in both types of memory, these results confirm the validity of this tgHD rat as a model for the human HD phenotype...
  20. doi request reprint Stress and the pregnant female: Impact on hippocampal cell proliferation, but not affective-like behaviors
    Jodi L Pawluski
    Department of Neuroscience, School of Mental Health and Neuroscience, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The Netherlands
    Horm Behav 59:572-80. 2011
    ..Understanding how stress affects the female during different reproductive states will aid in improving the health and well being of the mother and child...
  21. doi request reprint Phosphodiesterase type 5 (PDE5) inhibition improves object recognition memory: indications for central and peripheral mechanisms
    Olga A H Reneerkens
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, The Netherlands
    Neurobiol Learn Mem 97:370-9. 2012
    ..To further elucidate the underlying mechanisms, the cellular and subcellular localization of PDE5 needs to be determined...
  22. doi request reprint Object recognition testing: methodological considerations on exploration and discrimination measures
    Sven Akkerman
    Department of Psychiatry and Neuropsychology, School for Mental Health and NeuroScience MHeNS, European Graduate School of Neuroscience EURON, Maastricht University, Maastricht, The Netherlands
    Behav Brain Res 232:335-47. 2012
    ..Taken together, our findings suggest to take into consideration pre-experimental exposure (familiarization) to objects, habituation to treatment procedures, and the use of relative discrimination measures when using the ORT...
  23. doi request reprint Deep brain stimulation of the forniceal area enhances memory functions in experimental dementia: the role of stimulation parameters
    Sarah Hescham
    Department of Neuroscience, Maastricht University Medical Center, Maastricht, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Brain Stimul 6:72-7. 2013
    ..DBS of this region, using tailored stimulation parameters, has the potential to improve memory functions in conditions characterised by memory impairment...
  24. pmc Selective phosphodiesterase inhibitors: a promising target for cognition enhancement
    Olga A H Reneerkens
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Psychopharmacology (Berl) 202:419-43. 2009
    ..However, recently phosphodiesterases (PDEs) have gained increased attention as a potential new target for cognition enhancement. Inhibition of PDEs increases the intracellular availability of the second messengers cGMP and/or cAMP...
  25. ncbi request reprint Phosphodiesterase type 5 inhibition improves early memory consolidation of object information
    Jos Prickaerts
    Department of Psychiatry and Neuropsychology, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    Neurochem Int 45:915-28. 2004
    ..It is discussed that further studies are needed, immunocytochemical and behavioral, to better understand the cGMP-mediated molecular mechanisms underlying memory formation...
  26. doi request reprint The dorsal raphe nucleus and serotonin: implications for neuroplasticity linked to major depression and Alzheimer's disease
    Kimmo A Michelsen
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, European Graduate School of Neuroscience EURON, PO Box 616, 6200 MD Maastricht, The Netherlands
    Prog Brain Res 172:233-64. 2008
    ....
  27. doi request reprint Effects of prenatal stress exposure on soluble Aβ and brain-derived neurotrophic factor signaling in male and female APPswe/PS1dE9 mice
    Annerieke S R Sierksma
    Department of Psychiatry and Neuropsychology, Faculty of Health, Medicine and Life Science, School for Mental Health and NeuroScience MHeNS, Maastricht University, Maastricht, The Netherlands
    Neurochem Int 61:697-701. 2012
    ..Given that female mice both have higher proBDNF and Aβ levels, these findings suggest an underlying role for BDNF signaling and Aβ production in the selective vulnerability of women for MD and AD development...
  28. ncbi request reprint Prenatal maternal paroxetine treatment and neonatal mortality in the rat: a preliminary study
    Daniel L A van den Hove
    Department of Psychiatry and Neuropsychology, Research Institute Brain and Behavior, European Graduate School of Neuroscience, Maastricht University, Maastricht, The Netherlands
    Neonatology 93:52-5. 2008
    ..These results reiterate the need for further research on the effects of paroxetine treatment during gestation...
  29. pmc Prenatal stress and subsequent exposure to chronic mild stress influence dendritic spine density and morphology in the rat medial prefrontal cortex
    Kimmo A Michelsen
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, P O Box 616, 6200 MD Maastricht, The Netherlands
    BMC Neurosci 8:107. 2007
    ..The aim of this study was to reveal putative PS- and/or CMS-related changes in basal spine morphology and density of pyramidal neurons in the rat medial prefrontal cortex (mPFC)...
  30. ncbi request reprint Analysis of spatial orientation strategies of male and female Wistar rats in a Morris water escape task
    Arjan Blokland
    Faculty of Psychology, Maastricht University, The Netherlands
    Behav Brain Res 171:216-24. 2006
    ..CUE learning is not sex-dependent. The ability to use EGO strategies appears not to be different between male and female Wistar rats, but appears dependent on pre-exposure to the task...
  31. ncbi request reprint Delivery of DNA into the Central Nervous System via Electroporation
    Jochen De Vry
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, Netherlands
    Methods Mol Biol 1121:157-63. 2014
    ..This allows altering gene expression in very-well-defined areas of the brain while inducing minimal tissue damage. ..
  32. ncbi request reprint Functional investigations into the role of dopamine and serotonin in partial bilateral striatal 6-hydroxydopamine lesioned rats
    Bart Scholtissen
    Department of Psychiatry and Neuropsychology, Maastricht University, EURON, P O Box 616, 6200 MD Maastricht, The Netherlands
    Pharmacol Biochem Behav 83:175-85. 2006
    ..Taken together, since serotonergic ligands have the same effect as dopaminergic ligands on reaction time responding indicated that 5-HT and DA release are agonistically linked in control and 6-OHDA lesioned rats...
  33. doi request reprint Motor and non-motor behaviour in experimental Huntington's disease
    Dagmar H Zeef
    Department of Neuroscience, Maastricht University Medical School, Maastricht, The Netherlands
    Behav Brain Res 226:435-9. 2012
    ..Our data suggest that hyperkinetic features and reduced-anxiety in the tgHD rats are associated behaviours and are seen in the earlier stages of the disease...
  34. doi request reprint Liver X receptor activation restores memory in aged AD mice without reducing amyloid
    Tim Vanmierlo
    Department of Neuroscience, Maastricht University, Maastricht, The Netherlands
    Neurobiol Aging 32:1262-72. 2011
    ..However the beneficial effects of T0901317 on memory in the APPSLxPS1mut mice were independent of the Aβ plaque load in the hippocampus, but were associated with enhanced brain cholesterol turnover...
  35. ncbi request reprint Effects of acute tryptophan depletion on cognition, memory and motor performance in Parkinson's disease
    Bart Scholtissen
    Institute of Brain and Behaviour, Maastricht University, P O Box 616 6200 MD Maastricht, The Netherlands
    J Neurol Sci 248:259-65. 2006
    ..It is hypothesized that some of the non-motor symptoms are related to the serotonergic deficiency that is present in PD...
  36. ncbi request reprint Cognition- and anxiety-related behavior, synaptophysin and MAP2 immunoreactivity in the adult rat treated with a single course of antenatal betamethasone
    Matteo Bruschettini
    Department of Psychiatry and Neuropsychology, Research Institute Growth and Development, European Graduate School of Neuroscience, University of Maastricht, 6200 MD Maastricht, The Netherlands
    Pediatr Res 60:50-4. 2006
    ..Further research might elucidate whether the betamethasone effect on hippocampal neurons persists later in life and could affect the aging process increasing the risk for neuropathology of the adult...
  37. doi request reprint Object recognition testing: statistical considerations
    Sven Akkerman
    Department of Psychiatry and Neuropsychology, School for Mental Health and NeuroScience MHeNS, European Graduate School of Neuroscience EURON, Maastricht University, Maastricht, The Netherlands
    Behav Brain Res 232:317-22. 2012
    ..Finally, it was shown that differences in exploration levels may affect the statistical evaluation of group differences. Several suggestions for statistical analysis are given...
  38. doi request reprint Phosphodiesterases in neurodegenerative disorders
    Eva Bollen
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    IUBMB Life 64:965-70. 2012
    ..However, normalizing cyclic nucleotide signaling via PDE inhibition remains interesting for the treatment of neurodegenerative disorders...
  39. ncbi request reprint LDL receptor deficiency results in decreased cell proliferation and presynaptic bouton density in the murine hippocampus
    Monique Mulder
    Department of Molecular Cell Biology, University of Maastricht, Maastricht, The Netherlands
    Neurosci Res 59:251-6. 2007
    ..These findings support the notion that, similar to its role in the periphery, the LDLR is important for the cellular uptake of cholesterol in the brain and that disturbance of this process affects neuronal plasticity...
  40. doi request reprint Major depression, cognitive dysfunction and Alzheimer's disease: is there a link?
    Annerieke S R Sierksma
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, School for Mental Health and Neuroscience, Maastricht University, The Netherlands
    Eur J Pharmacol 626:72-82. 2010
    ..Obtaining more knowledge on their interactive role in the relation between MD and AD may eventually aid in the development of more effective treatment strategies...
  41. ncbi request reprint Performance of different mouse strains in an object recognition task
    Ayhan Sik
    Department of Psychiatry and Neuropsychology, Brain and Behaviour Institute, Maastricht University, 6200 MD Maastricht, The Netherlands
    Behav Brain Res 147:49-54. 2003
    ..The present data show that object memory can be assessed in mice and, in contrast to other memory tasks, appears to be less strain-dependent. The reliability of the discrimination measures is discussed...
  42. ncbi request reprint Assessment of spatial learning abilities of mice in a new circular maze
    Guido Koopmans
    Department of Psychiatry and Neuropsychology, Brain and Behaviour Institute, Maastricht University, Maastricht, The Netherlands
    Physiol Behav 79:683-93. 2003
    ..Further, our data with different strains indicate that different measures of behavior should be evaluated to assess the spatial learning performance of mice...
  43. doi request reprint In vivo electroporation of the central nervous system: a non-viral approach for targeted gene delivery
    Jochen De Vry
    Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht University, Maastricht, The Netherlands
    Prog Neurobiol 92:227-44. 2010
    ..Improving the knowledge about in vivo electroporation will pave the way for electroporation-enhanced gene therapy to treat brain carcinomas, as well as CNS disorders such as Alzheimer's disease, Parkinson's disease, and depression...
  44. doi request reprint Depressive symptoms following interferon-α therapy: mediated by immune-induced reductions in brain-derived neurotrophic factor?
    Gunter Kenis
    Department of Psychiatry and Neuropsychology, South Limburg Mental Health Research and Teaching Network, EURON, Maastricht University, Maastricht, The Netherlands
    Int J Neuropsychopharmacol 14:247-53. 2011
    ..These findings suggest that the effect of IFN-α-induced immune activation on depression may be explained in part by alterations in neuroprotective capacity, reflected by decreases in serum BDNF following IFN-α treatment...
  45. doi request reprint Long-term effects of prenatal allopurinol treatment on brain plasticity markers in low and normal birth weight piglets
    Jos Prickaerts
    Department of Psychiatry and Neuropsychology, School for Mental Health and NeuroScience MHeNS, Faculty of Health, Medicine and Life Science, Maastricht University, Universiteitssingel 50, 6229ER Maastricht, The Netherlands
    Int J Dev Neurosci 33:29-32. 2014
    ..In conclusion, antioxidant treatment administered in the last trimester might be a promising treatment for LBW neonates. ..
  46. ncbi request reprint cGMP, but not cAMP, in rat hippocampus is involved in early stages of object memory consolidation
    Jos Prickaerts
    Department of Psychiatry and Neuropsychology, European Graduate School of Neuroscience EURON, Maastricht University, P O Box 616, 6200 MD, Maastricht, The Netherlands
    Eur J Pharmacol 436:83-7. 2002
    ..In contrast, 8-Br-cAMP did not improve the memory performance at the doses tested. These results indicate that hippocampal cGMP but not cAMP is involved in early stages of consolidation of object memory...
  47. ncbi request reprint Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway
    Ronald Deumens
    Department of Psychiatry and Neuropsychology, Brain and Behavior Institute, 6200 MD Maastricht, The Netherlands
    Exp Neurol 175:303-17. 2002
    ..The choice of the behavioral parameters determines the use of unilateral or bilateral lesions, although it is obvious that the bilateral model mimics the human situation more closely...