An economic evaluation of adjustable and fixed dosing with budesonide/formoterol via a single inhaler in asthma patients: the ASSURE studyDavid Price
Respiratory Group, Department of General Practice and Primary Care, University of Aberdeen, Aberdeen, UK
Curr Med Res Opin 20:1671-9. 2004
..The difference in mean daily cost resulted in an annual per patient cost difference of pound sterling 65.70. Adjustable maintenance dosing with budesonide/formoterol provided equivalent QoL to fixed dosing at significantly lower cost...
The use of roflumilast in COPD: a primary care perspectiveDavid Price
Research in Real Life Ltd, Old Winery Business Park, Cawston, Norwich, UK
Prim Care Respir J 19:342-51. 2010
....
- Effect of montelukast for treatment of asthma in cigarette smokers
David Price
Centre of Academic Primary Care, University of Aberdeen, Aberdeen, United Kingdom
J Allergy Clin Immunol 131:763-71. 2013
..This study evaluates 10 mg/d montelukast and 250 μg of fluticasone propionate twice daily, each compared with placebo, in patients with self-reported active smoking (unable to quit) and asthma...
- Inhaler competence in asthma: common errors, barriers to use and recommended solutions
D Price
Centre for Academic Primary Care, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, UK
Respir Med 107:37-46. 2013
..Future direction with respect to research, policy needs and practice, together with education requirements in inhaler technique are described...
- Real-world perceptions of inhaled corticosteroid/long-acting β2-agonist combinations in the treatment of asthma
David Price
Centre of Academic Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen, AB25 2AY, UK
Respir Med 106:S4-8. 2012
..Further research is needed to help inform physician choice of ICS/LABA combinations for patients with asthma...
- A pragmatic single-blind randomised controlled trial and economic evaluation of the use of leukotriene receptor antagonists in primary care at steps 2 and 3 of the national asthma guidelines (ELEVATE study)
D Price
Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK
Health Technol Assess 15:1-132. 2011
Can asthma control be improved by understanding the patient's perspective?Rob Horne
Centre for Behavioural Medicine, School of Pharmacy University of London, UK
BMC Pulm Med 7:8. 2007
..An international panel of experts invited by the International Primary Care Respiratory Group considered the evidence and discussed the implications for primary care practice...
- Observational study comparing intranasal mometasone furoate with oral antihistamines for rhinitis and asthma
David Price
Academic Centre of Primary Care, University of Aberdeen, Aberdeen, UK
Prim Care Respir J 19:266-73. 2010
....
- Biochemical properties, pharmacokinetics and pharmacological response of tiotropium in chronic obstructive pulmonary disease patients
David Price
University of Aberdeen, Foresterhill Health Centre, Department of General Practice and Primary Care, Westburn Road, Aberdeen AB25 2AY, UK
Expert Opin Drug Metab Toxicol 5:417-24. 2009
..Chronic obstructive pulmonary disease (COPD) is a progressive disease with increasing incidence and mortality. Tiotropium is an inhaled long-acting anti-cholinergic for the maintenance treatment of COPD...
- Earlier diagnosis and earlier treatment of COPD in primary care
David Price
Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK
Prim Care Respir J 20:15-22. 2011
....
- Improving the differential diagnosis of chronic obstructive pulmonary disease in primary care
David B Price
Center of Academic Primary Care, University of Aberdeen, Foresterhill Health Center, Westburn Road, Aberdeen AB25 2AY, Scotland
Mayo Clin Proc 85:1122-9. 2010
....
- The use of omalizumab in asthma
David Price
Department of General Practice and Priamary Care, University of Aberdeen, Scotland, UK
Prim Care Respir J 17:62-72. 2008
..In contrast, assessment of response to omalizumab following 16 weeks of treatment appears to be reliably judged by physicians in clinical trial settings and may be a feasible means of selecting patients who should continue treatment...
- Salmeterol/fluticasone stable-dose treatment compared with formoterol/budesonide adjustable maintenance dosing: impact on health-related quality of life
David B Price
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen, UK
Respir Res 8:46. 2007
....
- Reassessing the evidence hierarchy in asthma: evaluating comparative effectiveness
David Price
Academic Centre of Primary Care, University of Aberdeen, Foresterhill Health Centre, UK
Curr Allergy Asthma Rep 11:526-38. 2011
..A combination of these approaches is preferable and necessary...
- International Primary Care Respiratory Group (IPCRG) Guidelines: management of allergic rhinitis
David Price
Department of General Practice, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen, AB25 2AY, UK
Prim Care Respir J 15:58-70. 2006
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- Improved adherence with once-daily versus twice-daily dosing of mometasone furoate administered via a dry powder inhaler: a randomized open-label study
David Price
Centre of Academic Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen, UK
BMC Pulm Med 10:1. 2010
..This study was designed to determine the effect of a once-daily administration of mometasone furoate administered via a dry powder inhaler (MF-DPI) on treatment adherence compared with a twice-daily administration...
- Poor communication may impair optimal asthma care: a qualitative study
Mandy Moffat
Department of General Practice and Primary Care, University of Aberdeen, Aberdeen, UK
Fam Pract 24:65-70. 2007
..Despite asthma being primarily managed in general practice and primary care, there is little research into the issues and tools which may impact on managing poorly controlled asthma in this setting...
- Cost effectiveness of leukotriene receptor antagonists versus inhaled corticosteroids for initial asthma controller therapy: a pragmatic trial
Edward C F Wilson
Faculty of Health, University of East Anglia, Norwich, UK
Pharmacoeconomics 28:585-95. 2010
..Information is lacking on the relative effectiveness and cost effectiveness--in a primary-care setting--of leukotriene receptor antagonists (LTRAs) as an alternative to inhaled corticosteroids (ICS) for initial asthma controller therapy...
- Device type and real-world effectiveness of asthma combination therapy: an observational study
David Price
Centre of Academic Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen, Scotland, UK
Respir Med 105:1457-66. 2011
..Selection of inhaler device type appears to influence real-world effectiveness of inhaled corticosteroids (ICS), but data are lacking on the role of inhaler device in ICS and long-acting β2-agonist (LABA) combination therapy for asthma...
- Leukotriene antagonists as first-line or add-on asthma-controller therapy
David Price
Centre of Academic Primary Care, University of Aberdeen, Aberdeen, United Kingdom
N Engl J Med 364:1695-707. 2011
..Most randomized trials of treatment for asthma study highly selected patients under idealized conditions...
- Achieving asthma control in practice: understanding the reasons for poor control
John Haughney
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen AB25 2AY, Scotland, UK
Respir Med 102:1681-93. 2008
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- Can a GP be a generalist and a specialist? Stakeholders views on a respiratory General Practitioner with a special interest service in the UK
Mandy A Moffat
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen AB41 6ST, UK
BMC Health Serv Res 6:62. 2006
..The objective of the current study is to explore the attitudes and views of stakeholders to the provision of a respiratory GPwSI service within the six PCTs in Leicester, UK...
- Inhaled corticosteroids for asthma: impact of practice level device switching on asthma control
Mike Thomas
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen, UK
BMC Pulm Med 9:1. 2009
..Our objective was to evaluate impact on asthma control of inhaler device switching without an accompanying consultation in general practice...
- Prescribing practices and asthma control with hydrofluoroalkane-beclomethasone and fluticasone: a real-world observational study
David Price
Centre of Academic Primary Care, University of Aberdeen, Aberdeen, United Kingdom
J Allergy Clin Immunol 126:511-8.e1-10. 2010
..Long-term randomized trials comparing asthma outcomes between inhaled corticosteroids in real-world populations are lacking. As such, rigorously conducted observational studies to complement the findings of randomized trials are needed...
- Spirometry in primary care case-identification, diagnosis and management of COPD
David Price
Centre for Academic Primary Care, University of Aberdeen, Scotland, UK
Prim Care Respir J 18:216-23. 2009
..Spirometry in primary care can also support patient education and may encourage smoking cessation and treatment adherence...
- High-dose inhaled corticosteroids versus add-on long-acting beta-agonists in asthma: an observational study
Mike Thomas
Department of General Practice and Primary Care, University of Aberdeen, Aberdeen, United Kingdom
J Allergy Clin Immunol 123:116-121.e10. 2009
..Controversy persists about the best option in routine practice...
- The Asthma Control Test (ACT) as a predictor of GINA guideline-defined asthma control: analysis of a multinational cross-sectional survey
Mike Thomas
Centre of Academic Primary Care, University of Aberdeen, Scotland, UK
Prim Care Respir J 18:41-9. 2009
..The ACT is a validated, 5-item, patient-completed measure of asthma control with a recall period of four weeks...
- Effectiveness of same versus mixed asthma inhaler devices: a retrospective observational study in primary care
David Price
Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK
Allergy Asthma Immunol Res 4:184-91. 2012
..The objective of this study was to compare outcomes for patients prescribed the same inhaler device versus mixed device types for asthma controller and reliever therapy...
- Clinical and cost effectiveness of mobile phone supported self monitoring of asthma: multicentre randomised controlled trial
Dermot Ryan
Academic Centre of Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen AB25 2ZD, UK
BMJ 344:e1756. 2012
..To determine whether mobile phone based monitoring improves asthma control compared with standard paper based monitoring strategies...
- High-dose inhaled corticosteroid use in childhood asthma: an observational study of GP prescribing
Mike Thomas
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen AB25 2AY
Br J Gen Pract 56:788-90. 2006
..Add-on therapy was lacking for almost half of these individuals. Some children were receiving treatment not in accord with current licences and evidence-based recommendations and, as such, may be at risk of adverse outcomes...
- Cost-effectiveness analysis of corticosteroid inhaler devices in primary care asthma management: A real world observational study
Linda Kemp
Research in Real Life Ltd, Old Winery Business Park, Cawston, Norwich, UK
Clinicoecon Outcomes Res 2:75-85. 2010
..To evaluate and compare real world cost-effectiveness of inhaled corticosteroids (ICS) administered by metered dose inhaler (MDI), breath-actuated MDI (BAI), or dry powder inhaler (DPI) in asthma...
- Efficacy and safety of tiotropium in COPD patients in primary care--the SPiRiva Usual CarE (SPRUCE) study
Daryl Freeman
Department of General Practice and Primary Care, University of Aberdeen, Aberdeen, UK
Respir Res 8:45. 2007
..In primary care, which is the most common setting for COPD management, many patients may have milder disease, and also may take a broad range of concomitant medication...
- High-dose inhaled corticosteroids and add-on therapy use in adults with asthma in the UK in 2003: an observational study
Mike Thomas
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen AB25 2AY, Scotland, UK
Prim Care Respir J 15:166-72. 2006
..To quantify use of high dose inhaled corticosteroids (ICS) and add-on therapy in adults, and children aged 12 and over, in the community...
- Practice development plans to improve the primary care management of acute asthma: randomised controlled trial
Juliet M Foster
Dept of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen, UK
BMC Fam Pract 8:23. 2007
..Our professional development plan aimed to improve the primary care management of acute asthma, which is known to be suboptimal...
- Effectiveness of inhaler types for real-world asthma management: retrospective observational study using the GPRD
David Price
Centre of Academic Primary Care, University of Aberdeen, Aberdeen, UK
J Asthma Allergy 4:37-47. 2011
..We compared asthma outcomes for ICS delivered via three different inhaler devices: pressurized metered-dose inhaler (pMDI), breath-actuated MDI (BAI), and dry powder inhaler (DPI)...
- The use of a modification of the Patient Enablement Instrument in asthma
John Haughney
Department of General Practice and Primary Care, University of Aberdeen, Aberdeen, Scotland, UK
Prim Care Respir J 16:89-92. 2007
....
- Antibiotic prescribing and outcomes of lower respiratory tract infection in UK primary care
Christopher C Winchester
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen, UK
Chest 135:1163-72. 2009
..This observational study aimed to investigate the role of antibiotics in the management of LRTI in the primary care setting in the United Kingdom...
- Breaking new ground: challenging existing asthma guidelines
David Price
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen AB25 2AY, UK
BMC Pulm Med 6:S6. 2006
..In this paper we review the limitations of current asthma guidelines and describe important issues and remaining questions regarding asthma guidelines for use, particularly in primary care...
- Cost effectiveness of leukotriene receptor antagonists versus long-acting beta-2 agonists as add-on therapy to inhaled corticosteroids for asthma: a pragmatic trial
Edward C F Wilson
Faculty of Health, University of East Anglia, Norwich, UK
Pharmacoeconomics 28:597-608. 2010
....
- EPOS Primary Care Guidelines: European Position Paper on the Primary Care Diagnosis and Management of Rhinosinusitis and Nasal Polyps 2007 - a summary
Mike Thomas
Department of General Practice and Primary Care, University of Aberdeen, Aberdeen, Scotland, UK
Prim Care Respir J 17:79-89. 2008
....
- Do people self-reporting information about chronic respiratory disease have corroborative evidence in their general practice medical records? A study of intermethod reliability
Lisa Iversen
Dept of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen, UK
Prim Care Respir J 16:162-8. 2007
..To use intermethod reliability to compare self-reported data about chronic respiratory disease and health service utilisation with data contained in general practice medical records...
- Choosing inhaler devices for people with asthma: current knowledge and outstanding research needs
John Haughney
Centre of Academic Primary Care, University of Aberdeen, Aberdeen AB25 2AY, Scotland, UK
Respir Med 104:1237-45. 2010
..we achieve better asthma outcomes? Do we have to refine inhaler device choice for each individual, or will we get better outcomes if we select our current best option in light of current knowledge and apply this on a population level?..
- Setting the standard for routine asthma consultations: a discussion of the aims, process and outcomes of reviewing people with asthma in primary care
Hilary Pinnock
Senior Clinical Research Fellow, Allergy and Respiratory Research Group, Centre of Population Health Sciences GP Section, University of Edinburgh, Scotland, UK
Prim Care Respir J 19:75-83. 2010
..Underpinned by a theoretical framework integrating professional reviews and patient self-care we discuss the practical barriers to implementing guided selfmanagement in routine clinical practice...
- Asthma-related health care resource use among asthmatic children with and without concomitant allergic rhinitis
Mike Thomas
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen, United Kingdom
Pediatrics 115:129-34. 2005
..A unified treatment strategy for asthma and allergic rhinitis, as recommended by the Allergic Rhinitis and Its Impact on Asthma initiative, might reduce the costs of treating these conditions...
- Database studies in asthma pharmacoeconomics: uses, limitations and quality markers
Mike Thomas
University of Aberdeen, Department of General Practice and Primary Care, Foresterhill Health Centre, Westburn Road, UK
Expert Opin Pharmacother 4:351-8. 2003
..High quality database studies can provide important epidemiological and economic information that can be of value in understanding the causes and effective management of asthma...
- Sub-optimal patient and physician communication in primary care consultations: its relation to severe and difficult asthma
Mandy Moffat
Department of General Practice and Primary Care, University of Aberdeen, UK
Prim Care Respir J 15:159-65. 2006
..Little is known about the views of patients, particularly those with severe and/or difficult asthma, towards their asthma control and their asthma-related primary care consultations...
- An exploratory, pragmatic, cluster randomised trial of practice nurse training in the use of asthma action plans
Jennifer A Cleland
Senior Clinical Lecturer, Department of General Practice and Primary Care, University of Aberdeen, Scotland, UK
Prim Care Respir J 16:311-8. 2007
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- Questions for COPD diagnostic screening in a primary care setting
Daryl Freeman
University of Aberdeen, Foresterhill Health Centre, Aberdeen, AB25 2AY, United Kingdom
Respir Med 99:1311-8. 2005
..This set of questions identified COPD patients with a sensitivity of 77.4--87.1% and specificity of 71.3--76.2%. CONCLUSIONS: A simple questionnaire can facilitate the diagnosis of COPD in a primary care setting...
- Cost-utility analysis of indacaterol in Germany: a once-daily maintenance bronchodilator for patients with COPD
David Price
Centre of Academic Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen AB25 2AY, UK
Respir Med 105:1635-47. 2011
....
- Current control and future risk in asthma management
Erika J Sims
Research in Real Life Ltd, Warren House, Sankence, Aylsham, Norfolk, UK
Allergy Asthma Immunol Res 3:217-25. 2011
..Here we review the current literature and discuss this in the context of primary care management of asthma...
- Pharmacoeconomics of asthma treatment
Jennifer Cleland
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, UK
Expert Opin Pharmacother 4:311-8. 2003
..Such information can come from 'pragmatic' randomised trials, from retrospective claims analysis from observational studies or using primary care clinical and prescribing databases...
- General practitioners with a special interest in respiratory medicine: national survey of UK primary care organisations
Hilary Pinnock
Division of Community Health Sciences, University of Edinburgh, 20, West Richmond St, Edinburgh, Scotland, EH8 9DX, UK
BMC Health Serv Res 5:40. 2005
....
- ABC of chronic obstructive pulmonary disease. Primary care and palliative care
Daryl Freeman
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen
BMJ 333:188-90. 2006
- Efficacy versus effectiveness trials: informing guidelines for asthma management
David Price
Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, UK
Curr Opin Allergy Clin Immunol 13:50-7. 2013
..This review summarizes the strengths and limitations of efficacy and effectiveness trials, results of recent effectiveness trials in asthma and initiatives promoting effectiveness research...
- Accessibility, acceptability, and effectiveness in primary care of routine telephone review of asthma: pragmatic, randomised controlled trial
Hilary Pinnock
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Aberdeen AB25 2AY
BMJ 326:477-9. 2003
..To determine whether routine review by telephone of patients with asthma improves access and is a good alternative to face to face reviews in general practices...
- Improving outcomes for asthma patients with allergic rhinitis: conclusions from the MetaForum conferences
David Price
Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen AB25 2AY, UK
BMC Pulm Med 6:S7. 2006
- Impact of comorbidities on asthma
Mike Thomas
Asthma UK Senior Research Fellow, Department of General Practice and Primary Care, University of Aberdeen, Foresterhill Health Centre, Westburn Road, Aberdeen, AB25 2AY, UK
Expert Rev Clin Immunol 4:731-42. 2008
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- The cost effectiveness of chlorofluorocarbon-free beclomethasone dipropionate in the treatment of chronic asthma: a cost model based on a 1-year pragmatic, randomised clinical study
David Price
Department of General Practice and Primary Care, University of Aberdeen, Fosterhill Health Centre, Aberdeen, United Kingdom
Pharmacoeconomics 20:653-64. 2002
....
- British Guideline on the Management of Asthma
Graham Douglas
Thorax 63:iv1-121. 2008
- The national montelukast survey
Neil Barnes
London Chest Hospital, London, United Kingdom
J Allergy Clin Immunol 115:47-54. 2005
..CONCLUSIONS: Montelukast is an effective, well-tolerated treatment for asthma in routine practice. The overall response rate and tolerability seen in this survey are similar to those reported in randomized clinical trials...
- Short-course montelukast for intermittent asthma in children: a randomized controlled trial
Colin F Robertson
Department of Respiratory Medicine, Royal Children s Hospital, Parkville, Victoria, Australia
Am J Respir Crit Care Med 175:323-9. 2007
..In children, intermittent asthma is the most common pattern and is responsible for the majority of exacerbations. Montelukast has a rapid onset of action and may be effective if used intermittently...
- Gastroesophageal reflux disease and asthma: a longitudinal study in UK general practice
Ana Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, C Almirante 28, 2o, 28004 Madrid, Spain
Chest 128:85-93. 2005
..The aim of our study was to investigate the temporal relationship between first diagnoses of GERD and asthma in general practice...
- Comparison of mometasone furoate dry powder inhaler and fluticasone propionate dry powder inhaler in patients with moderate to severe persistent asthma requiring high-dose inhaled corticosteroid therapy: findings from a noninferiority trial
Ulf Harnest
Institute for Medical Treatment Strategies, Munich, Germany
J Asthma 45:215-20. 2008
..Inhaled corticosteroids (ICSs) are one of the suggested first-line therapies for patients with persistent asthma of moderate severity...
- Cost-effectiveness of salmeterol xinafoate/fluticasone propionate combination inhaler in chronic asthma
Iolo Doull
Children s Hospital for Wales, Cardiff, UK
Curr Med Res Opin 23:1147-59. 2007
....
- Comparison of tiotropium bromide and combined ipratropium/salbutamol for the treatment of COPD: a UK General Practice Research Database 12-month follow-up study
Jane Griffin
Health Economics and Outcomes Research, Boehringer Ingelheim Limited, Bracknell, Berkshire, RG12 8YS, UK
Prim Care Respir J 17:104-10. 2008
..To compare the effectiveness of the long-acting anticholinergic, tiotropium with ipratropium/salbutamol in reducing the risk of exacerbations and COPD-related referrals in patients with COPD...
- The impact of asthma exacerbations on health-related quality of life in moderate to severe asthma patients in the UK
Andrew Lloyd
United BioSource Corporation, 20 Bloomsbury Square, London WC1A 2NS, UK
Prim Care Respir J 16:22-7. 2007
..The objective of this study was to report the impact of exacerbations on health-related quality of life (HRQL) and health utility in patients with moderate to severe asthma (BTS levels 4 & 5) in the UK...
- Treatment and outcomes in patients with asthma and allergic rhinitis in the United kingdom
Qiaoyi Zhang
Merck and Co, Whitehouse Station, NJ 08889 0100, USA
Int Arch Allergy Immunol 142:318-28. 2007
..Since allergic rhinitis in asthma patients is associated with worse asthma control, the treatment of the comorbid condition may improve outcomes...
- Exacerbations of chronic obstructive pulmonary disease--a patients' perspective
Rachel Adams
School of Population and Health Sciences, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, UK
Prim Care Respir J 15:102-9. 2006
..They suggest that the patient perspective of exacerbations is more complex than previously thought. These findings could be applied to clinical practice and research, facilitating focussed decisions on COPD management...
- Asthma out of control? A structured review of recent patient surveys
Stephen T Holgate
Infection, Inflammation and Repair AIR Division, Level F, South Block, MP810, Southampton General Hospital, Tremona Road, Southampton, SO16 6YD, UK
BMC Pulm Med 6:S2. 2006
..The primary goal of the present review was to assess patient perspectives on key issues in asthma and its management, as captured in patient surveys...
- Diagnosis of airway obstruction in primary care in the UK: the CADRE (COPD and Asthma Diagnostic/management REassessment) programme 1997-2001
Mike Pearson
Aintree Chest Centre, University Hospital Aintree, Liverpool, UK
Int J Chron Obstruct Pulmon Dis 1:435-43. 2006
..Asthma and COPD require different management strategies, but differentiation in primary care is difficult. This primary care support initiative observed the impact of spirometry and clinical assessment on the diagnosis of airway disease...
- Chronic obstructive pulmonary disease
David Price
BMJ 326:1046-7. 2003
- Comparative study of human steroid 5alpha-reductase isoforms in prostate and female breast skin tissues: sensitivity to inhibition by finasteride and epristeride
Mala Ranjan
Biochemistry Group, School of Biological Sciences, Wallace Building, University of Wales Swansea, Singleton Park, Swansea SA2 8PP, United Kingdom
Life Sci 71:115-26. 2002
....
- Maraviroc (UK-427,857), a potent, orally bioavailable, and selective small-molecule inhibitor of chemokine receptor CCR5 with broad-spectrum anti-human immunodeficiency virus type 1 activity
Patrick Dorr
Discovery Biology, Pfizer Global Research and Development Sandwich Laboratories, Kent CT13 9NJ, United Kingdom
Antimicrob Agents Chemother 49:4721-32. 2005
..Clinical trials are ongoing to further investigate the potential of using maraviroc for the treatment of HIV-1 infection and AIDS...
- ARIA update: I--Systematic review of complementary and alternative medicine for rhinitis and asthma
Giovanni Passalacqua
Allergy and Respiratory Diseases, University of Genoa, Italy
J Allergy Clin Immunol 117:1054-62. 2006
..There are also unresolved safety concerns. Therapeutic efficacy of complementary-alternative treatments for rhinitis and asthma is not supported by currently available evidence...
- The BetterCare judgment--a challenge to health care
Allyson M Pollock
BMJ 326:236-7. 2003
- General practitioners with a special clinical interest: a model for improving respiratory disease management
Sian Williams
Br J Gen Pract 52:838-43. 2002
..We explore how the role of GPSCI might work using the field of respiratory medicine as an exemplar. The concept is transferable to other therapeutic areas...
- Toremifene for the prevention of prostate cancer in men with high grade prostatic intraepithelial neoplasia: results of a double-blind, placebo controlled, phase IIB clinical trial
David Price
Regional Urology L L C, 255 Bert Kouns, Shreveport, LA 71106, USA
J Urol 176:965-70; discussion 970-1. 2006
..A randomized, double-blind, dose finding, placebo controlled, parallel group clinical study was done to determine the incidence of prostate cancer in men with high grade prostatic intraepithelial neoplasia treated with toremifene...
- Virological and immunological effects of short-course antiretroviral therapy in primary HIV infection
Sarah Fidler
Wright Fleming Institute, Department of GUM and Communicable Diseases, Faculty of Medicine, Imperial College, St Mary's Hospital, London, UK
AIDS 16:2049-54. 2002
..However, PHI is highly heterogeneous, and a large-scale randomized trial of SCART at PHI is now needed...
- Cost effectiveness of asthma management strategies
Mike Thomas
Pharmacoeconomics 20:789. 2002
- Extending choice in the NHS
David Price
BMJ 325:293-4. 2002
- Professional and patient attitudes to using mobile phone technology to monitor asthma: questionnaire survey
Hilary Pinnock
Division of Community Health Sciences GP section, University of Edinburgh, 20 West Richmond St, Edinburgh EH8 9DX, UK
Prim Care Respir J 15:237-45. 2006
..We aimed to explore the attitudes of patients and primary care professionals to using mobile technology in order to monitor asthma...
- Intelligent systems provide security
David Price
Health Estate 60:55. 2006
- Requirements for medications commonly used in the treatment of allergic rhinitis. European Academy of Allergy and Clinical Immunology (EAACI), Allergic Rhinitis and its Impact on Asthma (ARIA)
Jean Bousquet
Allergy 58:192-7. 2003
- COPD screening efforts in primary care: what is the yield?
David G Tinkelman
Health Initiatives, National Jewish Medical and Research Center, Denver, USA
Prim Care Respir J 16:41-8. 2007
..To document the extent of underdiagnosis in a high risk group of ambulatory patients, we performed spirometry in smokers aged 40 years and over drawn from general practices in two countries...
- A prospective trial of structured treatment interruptions in human immunodeficiency virus infection
Catherine Fagard
Division of Infectious Diseases, Geneva Unmiversity Hospital, 1211 Geneva 14, Switzerland
Arch Intern Med 163:1220-6. 2003
..Treatment interruptions did not provoke clinical complications, and there was little drug resistance. Comparative trials will have to show what benefit, if any, is associated with intermittent, as opposed to continuous treatment...
- Initiation of insulin glargine therapy in type 2 diabetes subjects suboptimally controlled on oral antidiabetic agents: results from the AT.LANTUS trial
M Davies
Department of Cardiovascular Sciences, University of Leicester, Leicester, UK
Diabetes Obes Metab 10:387-99. 2008
..This subgroup analysis investigated the initiation of once-daily glargine therapy in patients suboptimally controlled on multiple OADs...
- Befriending carers of people with dementia: randomised controlled trial
Georgina Charlesworth
Centre for Behavioural and Social Sciences in Medicine, University College London, London W1W 7EJ
BMJ 336:1295-7. 2008
..To evaluate the effectiveness of a voluntary sector based befriending scheme in improving psychological wellbeing and quality of life for family carers of people with dementia...
- Best interests and potential organ donors
John Coggon
Centre for Social Ethics and Policy and Institute for Science, Ethics and Innovation, School of Law, University of Manchester, Manchester M13 9PL
BMJ 336:1346-7. 2008
- Co-morbid disease in COPD--more than a coincidence
Alan J Crockett
Int J Chron Obstruct Pulmon Dis 2:399-400. 2007
- Concerns of patients with allergic rhinitis: the Allergic Rhinitis Care Programme in South Africa
Robin John Green
Department of Paediatrics, University of Pretoria, South Africa
Prim Care Respir J 16:299-303. 2007
..Although primary symptoms cause morbidity in their own right, these symptoms are significantly aggravated by the impact of cognitive dysfunction and quality of life...
- Randomised phase 2 trial of SIR-Spheres plus fluorouracil/leucovorin chemotherapy versus fluorouracil/leucovorin chemotherapy alone in advanced colorectal cancer
Guy Van Hazel
Mount Hospital, Western Australia, Australia
J Surg Oncol 88:78-85. 2004
..The combination of SIR-Spheres plus systemic chemotherapy is now the subject of ongoing trials to further define patient benefit...
- Who owns my body--thee or me? The human tissue story continues
Ash Samanta
University Hospitals of Leicester NHS Trust
Clin Med 4:327-31. 2004
..An awareness of these developments is of relevance to all practising doctors...
- The market in primary care
Allyson M Pollock
Centre for International Public Health Policy, University of Edinburgh, Edinburgh EH8 9AG
BMJ 335:475-7. 2007
- From Cosmos and Damian to Van Velzen: the human tissue saga continues
David Price
De Montfort University, Leicester, UK
Med Law Rev 11:1-47. 2003
- NHS and the Health and Social Care Bill: end of Bevan's vision?
Allyson M Pollock
Public Health Policy Unit, School of Public Policy, University College London, London WC1H 9QU
BMJ 327:982-5. 2003
- Clinical management. Getting up to scratch
David Price
Aberdeen University
Health Serv J 115:30-2. 2005
..Primary care trusts can help to improve local allergy services by commissioning practice-based allergy clinics or integrated allergy/asthma services...
- The UK General Practice Airways Group (GPIAG): its formation, development, and influence on the management of asthma and other respiratory diseases over the last twenty years
Mark L Levy
Prim Care Respir J 16:132-9. 2007
..quot;..
- The public health implications of world trade negotiations on the general agreement on trade in services and public services
Allyson M Pollock
Public Health Policy Unit, School of Public Policy, University College London, 29 30 Tavistock Square, WC1H 9QU, London, UK
Lancet 362:1072-5. 2003
..We conclude that national autonomy over health policy is not preserved under GATS, and that accordingly, there is a role for international standards that protect public services from the adverse effect of trade and market forces...
- Prenatal antibiotic exposure and subsequent atopy
Mike Thomas
Am J Respir Crit Care Med 167:1578; author reply 1578-9. 2003
- Chronic cough. Article is not consistent with WHO initiative on rhinitis and asthma
Mike Thomas
BMJ 326:1036. 2003
