James G D Prendergast

Summary

Publications

  1. ncbi request reprint Sequence-level mechanisms of human epigenome evolution
    James G D Prendergast
    The Roslin Institute, The University of Edinburgh, Midlothian, United Kingdom
    Genome Biol Evol 6:1758-71. 2014
  2. pmc A genome-wide screen in human embryonic stem cells reveals novel sites of allele-specific histone modification associated with known disease loci
    James G D Prendergast
    MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK
    Epigenetics Chromatin 5:6. 2012
  3. pmc Sequencing and analysis of an Irish human genome
    Pin Tong
    Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
    Genome Biol 11:R91. 2010
  4. pmc Widespread signatures of recent selection linked to nucleosome positioning in the human lineage
    James G D Prendergast
    MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh EH4 2XU, United Kingdom
    Genome Res 21:1777-87. 2011
  5. pmc Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21
    Albert Tenesa
    Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit, Edinburgh EH4 2XU, UK
    Nat Genet 40:631-7. 2008
  6. pmc Chromatin structure and evolution in the human genome
    James G D Prendergast
    Colon Cancer Genetics Group, Division of Oncology, University of Edinburgh, Western General Hospital, Edinburgh, UK
    BMC Evol Biol 7:72. 2007

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Sequence-level mechanisms of human epigenome evolution
    James G D Prendergast
    The Roslin Institute, The University of Edinburgh, Midlothian, United Kingdom
    Genome Biol Evol 6:1758-71. 2014
    ....
  2. pmc A genome-wide screen in human embryonic stem cells reveals novel sites of allele-specific histone modification associated with known disease loci
    James G D Prendergast
    MRC Human Genetics Unit, MRC Institute of Genetics and Molecular Medicine, University of Edinburgh, Western General Hospital, Crewe Road, Edinburgh, EH4 2XU, UK
    Epigenetics Chromatin 5:6. 2012
    ..abstract:..
  3. pmc Sequencing and analysis of an Irish human genome
    Pin Tong
    Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland
    Genome Biol 11:R91. 2010
    ....
  4. pmc Widespread signatures of recent selection linked to nucleosome positioning in the human lineage
    James G D Prendergast
    MRC Human Genetics Unit, Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh EH4 2XU, United Kingdom
    Genome Res 21:1777-87. 2011
    ..Recent signatures of selection linked to genomic features as ubiquitous as the nucleosome have important implications for human genome evolution and disease...
  5. pmc Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21
    Albert Tenesa
    Colon Cancer Genetics Group, Institute of Genetics and Molecular Medicine, University of Edinburgh and MRC Human Genetics Unit, Edinburgh EH4 2XU, UK
    Nat Genet 40:631-7. 2008
    ..008) and rs4939827 (P < 0.009). Carrying all six possible risk alleles yielded OR = 2.6 (95% CI = 1.75-3.89) for CRC. These findings extend our understanding of the role of common genetic variation in CRC etiology...
  6. pmc Chromatin structure and evolution in the human genome
    James G D Prendergast
    Colon Cancer Genetics Group, Division of Oncology, University of Edinburgh, Western General Hospital, Edinburgh, UK
    BMC Evol Biol 7:72. 2007
    ..Using the results of a recent genome-wide analysis of open and closed human chromatin structures we have investigated the global association between divergence, selection and chromatin structure for the first time...