Recovery from anti-recombinant-human-erythropoietin associated pure red cell aplasia in end-stage renal disease patients after renal transplantationKearkiat Praditpornsilpa
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
Nephrol Dial Transplant 20:626-30. 2005
- Renal pathology and HIV infection in Thailand
K Praditpornsilpa
Department of Medicine, Police General Hospital, Bangkok, Thailand
Am J Kidney Dis 33:282-6. 1999
..Although the data in this study are limited to 26 HIV-infected Thai patients, we believe that HIVAN is uncommon in the Asian HIV-infected population...
The need for robust validation for MDRD-based glomerular filtration rate estimation in various CKD populationsKearkiat Praditpornsilpa
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Nephrol Dial Transplant 26:2780-5. 2011
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- Biosimilar recombinant human erythropoietin induces the production of neutralizing antibodies
Kearkiat Praditpornsilpa
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Kidney Int 80:88-92. 2011
..Thus, subcutaneous injection of biosimilar r-HuEpo can cause adverse immunological effects. A large, long-term, pharmacovigilance study is necessary to monitor and ensure patient safety for these agents...
- Effects of different levels of endotoxin contamination on inflammatory cytokine production by peripheral blood mononuclear cells after high-flux hemodialysis
Kearkiat Praditpornsilpa
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Blood Purif 32:112-6. 2011
..001 to 2.0 EU/ml. This difference has prompted an investigation on the production of proinflammatory cytokines and counter-inflammatory mediators of peripheral blood mononuclear cells (PBMCs) after high-flux dialysis...
- Prevalence trend of renal replacement therapy in Thailand: impact of health economics policy
Kearkiat Praditpornsilpa
The Nephrology Society of Thailand, Bangkok, Thailand
J Med Assoc Thai 94:S1-6. 2011
..The present study was conducted to determine whether the increase of RRT penetration by national health policy could impact the national RRT prevalence...
- Outcome of microemulsion cyclosporine C2 concentration monitoring in kidney transplantation
Kearkiat Praditpornsilpa
Division of Nephrology, Department of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
Clin Transplant 19:335-9. 2005
..The international consensus for C(2) concentraion may be too high for Asian ethnic kidney transplant recipients. The data from this study indicated lower than recommended C(2) concentraion as an appropriate C(2) target concentraion...
- New concepts in organ transplantation
K Praditpornsilpa
Division of Nephrology, Department of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
Transplant Proc 36:1228-31. 2004
..Due to the array of adverse reactions to the available immunosuppressive drugs, these new approaches aim not only to augment long-term graft survival, but also minimize the associated toxicities...
- Upregulation of IL-2 but not IL-15 by allorecognition in human mixed lymphocyte culture
K Praditpornsilpa
Division of Nephrology, Department of Medicine, Faculty of Medicine K P, Chulalongkorn University Hospital, Bangkok, Thailand
Transplant Proc 35:1599-602. 2003
..In conclusion, experiments in the MLC model suggest that allorecognition upregulates IL-2 but not IL-15 expression...
- Alleviation of renal and pulmonary injury by immunomodulation in leptospirosis: hamster model
Kearkiat Praditpornsilpa
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
J Med Assoc Thai 89:S178-87. 2006
..The authors determined whether the current immunosuppressive agents could alleviate the inflammation and minimize the organ injury in hamster model...
- The association of anti-r-HuEpo-associated pure red cell aplasia with HLA-DRB1*09-DQB1*0309
Kearkiat Praditpornsilpa
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
Nephrol Dial Transplant 24:1545-9. 2009
..This allele is rare in Caucasian (<1%) but more common in Thai population (8.4-12.5%). This study was aimed to investigate the possible association between HLA-DRB1*09 or other specific HLA and anti-r-HuEpo associated PRCA...
- Regional citrate anticoagulation reduces polymorphonuclear cell degranulation in critically ill patients treated with continuous venovenous hemofiltration
Khajohn Tiranathanagul
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok
Ther Apher Dial 15:556-64. 2011
..In conclusion, citrate, utilized as a regional anticoagulant in CVVH, can reduce both membrane bioincompatibility-induced and systemic oxidative stress and inflammation, and can prolong CVVH circuit survival time...
- Efficacy of convective-controlled double high-flux hemodiafiltration versus on-line hemodiafiltration: 1-year prospective study
Paweena Susantitaphong
Extracorporeal Multiorgan Support Dialysis Excellent Center, Chulalongkorn University, Bangkok, Thailand
Blood Purif 29:35-43. 2010
..A recent cross-sectional study demonstrated that convective-controlled double high-flux hemodiafiltration (CC-HDF) could yield equivalent removal of small and middle molecule uremic toxins to on-line hemodiafiltration (OL-HDF)...
- On-line hemodiafiltration in Southeast Asia: a three-year prospective study of a single center
Khajohn Tiranathanagul
Division of Nephrology, Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand
Ther Apher Dial 13:56-62. 2009
..The potential benefits may include the effective removal of higher molecular weight uremic toxins and an improved nutritional status, along with a low inflammatory state...
- Study of cyclosporine level at 2 hours after administration in preoperative kidney transplant recipients for prediction of postoperative optimal cyclosporine dose
Narin Sukhavasharin
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital
J Med Assoc Thai 89:S15-20. 2006
..CONCLUSION: The early postoperative optimal cyclosporine dose can be effectively predicted by pre-transplant C2 measurement as conducted in the present study...
- Etiologies of glomerular diseases in Thailand: a renal biopsy study of 506 cases
Talerngsak Kanjanabuch
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
J Med Assoc Thai 88:S305-11. 2005
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- Efficacy comparison between simple mixed-dilution and simple mid-dilution on-line hemodiafiltration techniques: a crossover study
Paweena Susantitaphong
Division of Nephrology, Department of Medicine Extracorporeal Multiorgan Support Dialysis Excellent CenterDepartments of Immunology Pharmacology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Artif Organs 36:1059-65. 2012
..There were no intradialytic complications in both techniques. Simple mixed-dilution OL-HDF could provide greater efficacy for small- and middle-molecule clearances and acceptable potential risks, while phosphate removal is comparable...
- Efficacy of separated system continuous venovenous hemofiltration in critical acute kidney injury
Paweena Susantitaphong
Extracorporeal Multiorgan Support Dialysis Center of Excellence Department of Medicine, Division of Nephrology, Center of Excellence for Critical Care Nephrology, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
Ther Apher Dial 15:475-80. 2011
..It could thus be an effective, alternative treatment for critical acute kidney injury patients when the integrated mode is unavailable...
- Pharmacokinetics of sirolimus in Thai healthy volunteers
Asada Leelahavanichkul
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
J Med Assoc Thai 88:S157-62. 2005
..There are differences in pharmacokinetics of sirolimus between Thais and Caucasians...
- A rare case of chylous ascites and chyluria in an adult nephrotic syndrome with focal segmental glomerulosclerosis
Songkiat Lewsuwan
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
J Med Assoc Thai 89:S253-6. 2006
..Hypoalbuminemia-induced bowel edema may predispose to change the permeability of mucosal or serosal lymphatics. This could result in chylous ascites but the cause of chyluria could not be determined in this case...
- Effective bilirubin reduction by single-pass albumin dialysis in liver failure
Ussanee Boonsrirat
Department of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand
Artif Organs 33:648-53. 2009
..In conclusion, SPAD is salutarily effective in reducing bilirubin in patients with liver failure. The procedure is safe and simply set up...
- Erythropoietin and its non-erythropoietic derivative: do they ameliorate renal tubulointerstitial injury in ureteral obstruction?
Nattachai Srisawat
Division of Nephrology, Department of Medicine, Chulalongkorn University, Bangkok, Thailand
Int J Urol 15:1011-7. 2008
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- Long-term efficacy of pre- and post-dilution online hemodiafiltration with dialyzer reuse
Khajohn Tiranathanagul
Division of Nephrology, Department of Medicine, King Chulalongkorn Memorial Hospital, Thai Red Cross Society and Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
J Med Assoc Thai 95:650-6. 2012
..Previous studies regarding online HDF utilized single-use dialyzer The present study was conducted to compare the long-term clinical parameters between pre- and post-dilution online HDF with the reuse dialyzer..
- Measurement of vascular access flow by online clearance monitor in online hemodiafiltration
Khajohn Tiranathanagul
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand
Blood Purif 32:195-201. 2011
..Recently, online clearance monitoring (OCM) in an online hemodiafiltration (OL-HDF) machine could accurately measure urea dialyzer clearance. In the present study, OCM was utilized to assess the Qa in OL-HDF...
- Impact of the heterozygous TPMT*1/*3C genotype on azathioprine-induced myelosuppression in kidney transplant recipients in Thailand
Suda Vannaprasaht
Department of Pharmacology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
Clin Ther 31:1524-33. 2009
..The frequency of TPMT*3C has been reported to be higher in the Thai population than in other Asian populations, possibly putting the Thais at higher risk for myelosuppression...
- The clinicopathology and outcome of post-infectious glomerulonephritis: experience in 36 adults
Nattachai Srisawat
Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
J Med Assoc Thai 89:S157-62. 2006
..Of interest, all of the ESRD patients were caused by post non-Streptococcal GN. Even though, no statistic was achieved; it might reflect the aggressiveness of non-Streptococcal pathogen...
- Neutralizing antibody response after intradermal rabies vaccination in hemodialysis patients
Theeraphab Tanisaro
Division of Nephrology, Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Thailand
Vaccine 28:2385-7. 2010
..No serious adverse reactions were detected. In conclusion, chronic HD patients receiving adequate dialysis have excellent protective immunological response after intradermal post-exposure rabies vaccination as WHO recommendation...
- Effective determination of dry weight by intradialytic bioimpedance analysis in hemodialysis
Kamonrat Chongthanakorn
Division of Nephrology, Department of Medicine, Faculty of Medicine, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand
Blood Purif 27:235-41. 2009
..The new dry weight (DW) assessment technique by intradialytic sequential bioimpedance analysis (BIA) was evaluated in this study...
- Oxidative stress from rapid versus slow intravenous iron replacement in haemodialysis patients
Khajohn Tiranathanagul
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Hospital, Bangkok, Thailand
Nephrology (Carlton) 9:217-22. 2004
..The rapid injection method would be the preferred method of intravenous iron administration because it is more convenient while still retaining the safety profile...
- The incidence of peritoneal dialysis-related infection in Thailand: a nationwide survey
Talerngsak Kanjanabuch
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
J Med Assoc Thai 94:S7-12. 2011
..Since PD-related infection is the Achilles' heel of PD, this retrospective study was conducted to examine the magnitude of PD-related infection in Thailand under the "PD First" policy...
- Effect of high dose ergocalciferol in chronic kidney disease patients with 25-hydroxyvitamin D deficiency
Thananda Trakarnvanich
Division of Nephrology, Department ofMedicine, BMA Medical College and Vajira Hospital, Bangkok, Thailand
J Med Assoc Thai 93:885-91. 2010
..To evaluate 25 hydroxyvitamin D (25-OH-D) deficiency in a cohort ofpredialysis CKD patients and the treatment effect and safety of high dose ergocalciferol supplement in predialysis CKD...
- A simple efficient technique of 'mid-dilution' on-line hemodiafiltration
Paweena Susantitaphong
Extracorporeal Multiorgan Support Dialysis Excellent Center, King Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand
Blood Purif 28:93-101. 2009
..Both standard pre- and post-dilution have limitations. Mid-dilution OL-HDF (Nephros OLpur) was invented to overcome the disadvantages of both standard modes, but such a cartridge is only available in limited centers and is expensive...
- Comparisons between validated estimated glomerular filtration rate equations and isotopic glomerular filtration rate in HIV patients
Kearkiat Praditpornsilpa
Division of Nephrology, Department of Medicine, Faculty of Medicine, Chulalongkorn University Bangkok, Thailand
AIDS 26:1781-8. 2012
..We validated the available eGFR equations and compared them to the plasma Tc-diethylenetriaminepentaacetic acid (Tc-DTPA) clearance in HIV-infected patients...
- The effectiveness of on-line hemodiafiltration on beta-2 microglobulin clearance in end stage renal disease
Anchana Panich
Department of Medicine, Pra Chom Klao Hospital, Petchaburi
J Med Assoc Thai 89:S1-8. 2006
..HDF125 provided more total beta2M clearance than HDF75 from the convection/diffusion mechanism while the adsorptive mechanisms were equal...
- Citrate attenuates tubulointerstitial fibrosis in 5/6 nephrectomized rats by decreasing transforming growth factor-beta1
Krissanapong Manotham
Nephrology Unit, Medicine, Lerdsin General Hospital
J Med Assoc Thai 89:S168-77. 2006
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- Target quantity for twice-a-week hemodialysis: the EKR (equivalent renal urea clearance) approach
Krissanapong Manotham
Nephrology Unit, Medicine, Leardsin General Hospital
J Med Assoc Thai 89:S79-85. 2006
..25, respectively while those of URR were 82.89 and 84.52%, respectively. CONCLUSION: For twice-a-week HD, to have the EKRc level above 13 mL/min, at 95% confidence, the Kt/V should exceed 2.2 and the URR should exceed 85% per session...
