P Vale

Summary

Country: Portugal

Publications

  1. ncbi Comparison between HPLC and a commercial immunoassay kit for detection of okadaic acid and esters in Portuguese bivalves
    P Vale
    Instituto de Investigação das Pescas e do Mar, Lisbon, Portugal
    Toxicon 37:1565-77. 1999
  2. ncbi Assessment of the quantitative determination of paralytic shellfish poisoning toxins by pre-column derivatization and elimination of interfering compounds by solid-phase extraction
    P Vale
    Instituto Nacional de Investigação Agrária e das Pescas IPIMAR, Av Brasilia, P 1449 006 Lisbon, Portugal
    Food Addit Contam 22:838-46. 2005
  3. ncbi Differential dynamics of dinophysistoxins and pectenotoxins, part II: offshore bivalve species
    Paulo Vale
    Instituto Nacional de Investigação Agrária e das Pescas IPIMAR, Av Brasilia, 1449 006 Lisboa, Portugal
    Toxicon 47:163-73. 2006
  4. ncbi Detailed profiles of 7-O-acyl esters in plankton and shellfish from the Portuguese coast
    Paulo Vale
    Instituto Nacional de Investigação Agrária e das Pescas IPIMAR, Av Brasilia, 1449 006 Lisboa, Portugal
    J Chromatogr A 1128:181-8. 2006
  5. doi Fate of benzoate paralytic shellfish poisoning toxins from Gymnodinium catenatum in shellfish and fish detected by pre-column oxidation and liquid chromatography with fluorescence detection
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos, IPIMAR, Avenida de Brasília s n, 1449 006 Lisbon, Portugal
    J Chromatogr A 1190:191-7. 2008
  6. doi Confirmation by LC-MS/MS of azaspiracids in shellfish from the Portuguese north-western coast
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos, Avenida Brasília s n, Lisbon, Portugal
    Toxicon 51:1449-56. 2008
  7. doi Atypical profiles of paralytic shellfish poisoning toxins in shellfish from Luanda and Mussulo bays, Angola
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos L IPIMAR INRB L IPIMAR, Av Brasilia, S N, 1449 006 Lisboa, Portugal
    Toxicon 53:176-83. 2009
  8. doi Toxin composition of a Prorocentrum lima strain isolated from the Portuguese coast
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos IPIMAR INRB IPIMAR, Av Brasilia, S N, 1449 006 Lisboa, Portugal
    Toxicon 54:145-52. 2009
  9. doi Metabolites of saxitoxin analogues in bivalves contaminated by Gymnodinium catenatum
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos, I P L IPIMAR, Avenida de Brasília s n, 1449 006 Lisbon, Portugal
    Toxicon 55:162-5. 2010
  10. doi Assessment of a new lateral flow immunochromatographic (LFIC) assay for the okadaic acid group of toxins using naturally contaminated bivalve shellfish from the Portuguese coast
    P Vale
    Instituto Nacional dos Recursos Biologicos IPIMAR, Lisbon, Portugal
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 26:214-20. 2009

Collaborators

Detail Information

Publications26

  1. ncbi Comparison between HPLC and a commercial immunoassay kit for detection of okadaic acid and esters in Portuguese bivalves
    P Vale
    Instituto de Investigação das Pescas e do Mar, Lisbon, Portugal
    Toxicon 37:1565-77. 1999
    ..On sandy beaches of the Portuguese southern coast, were rock mussels are not so abundant, they should be screened more often than other species in order to prevent diarrhoea in humans...
  2. ncbi Assessment of the quantitative determination of paralytic shellfish poisoning toxins by pre-column derivatization and elimination of interfering compounds by solid-phase extraction
    P Vale
    Instituto Nacional de Investigação Agrária e das Pescas IPIMAR, Av Brasilia, P 1449 006 Lisbon, Portugal
    Food Addit Contam 22:838-46. 2005
    ..The implementation of the HPLC methodology achieved so far allows a high degree of consumer protection without the need to resource to animal sacrifice...
  3. ncbi Differential dynamics of dinophysistoxins and pectenotoxins, part II: offshore bivalve species
    Paulo Vale
    Instituto Nacional de Investigação Agrária e das Pescas IPIMAR, Av Brasilia, 1449 006 Lisboa, Portugal
    Toxicon 47:163-73. 2006
    ..The half-lives of PTX2sas found in D. trunculus and S. solida were similar to that found in a previous study with the cockle, Cerastoderma edule, but longer than found in the blue mussel M. galloprovinciallis...
  4. ncbi Detailed profiles of 7-O-acyl esters in plankton and shellfish from the Portuguese coast
    Paulo Vale
    Instituto Nacional de Investigação Agrária e das Pescas IPIMAR, Av Brasilia, 1449 006 Lisboa, Portugal
    J Chromatogr A 1128:181-8. 2006
    ..Esters were also found in plankton, predominantly with C16:0. Total esters in plankton were not higher than 10%, not enough to justify per se the high levels found in bivalves...
  5. doi Fate of benzoate paralytic shellfish poisoning toxins from Gymnodinium catenatum in shellfish and fish detected by pre-column oxidation and liquid chromatography with fluorescence detection
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos, IPIMAR, Avenida de Brasília s n, 1449 006 Lisbon, Portugal
    J Chromatogr A 1190:191-7. 2008
    ..These last analogues are detected by common HPLC methods used for food protection...
  6. doi Confirmation by LC-MS/MS of azaspiracids in shellfish from the Portuguese north-western coast
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos, Avenida Brasília s n, Lisbon, Portugal
    Toxicon 51:1449-56. 2008
    ..Thus, there appears overall a moderate likelihood of occurrence of AZAs in the range that may be relevant to consumers...
  7. doi Atypical profiles of paralytic shellfish poisoning toxins in shellfish from Luanda and Mussulo bays, Angola
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos L IPIMAR INRB L IPIMAR, Av Brasilia, S N, 1449 006 Lisboa, Portugal
    Toxicon 53:176-83. 2009
    ..This contamination might not be characteristic of a dinoflagellate blooming, but could be related to a persistent cyanobacterial contamination, due to the strong sewage pollution of the area...
  8. doi Toxin composition of a Prorocentrum lima strain isolated from the Portuguese coast
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos IPIMAR INRB IPIMAR, Av Brasilia, S N, 1449 006 Lisboa, Portugal
    Toxicon 54:145-52. 2009
    ..The parent toxins found were okadaic acid (OA) and dinophysistoxin-1 (DTX1). The major diol esters were D8- and D9- congeners of both OA and DTX1...
  9. doi Metabolites of saxitoxin analogues in bivalves contaminated by Gymnodinium catenatum
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos, I P L IPIMAR, Avenida de Brasília s n, 1449 006 Lisbon, Portugal
    Toxicon 55:162-5. 2010
    ..catenatum without a proper study of hydroxybenzoate and hydroxylated M-toxins...
  10. doi Assessment of a new lateral flow immunochromatographic (LFIC) assay for the okadaic acid group of toxins using naturally contaminated bivalve shellfish from the Portuguese coast
    P Vale
    Instituto Nacional dos Recursos Biologicos IPIMAR, Lisbon, Portugal
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 26:214-20. 2009
    ..While prototype A was not sensitive enough, prototype B had too many false positives to be of use to the shellfish industry or in a monitoring program...
  11. ncbi Is there a risk of human poisoning by azaspiracids from shellfish harvested at the Portuguese coast?
    Paulo Vale
    Instituto Nacional de Investigação Agrária e das Pescas IPIMAR, Av Brasilia, 1449 006 Lisboa, Portugal
    Toxicon 44:943-7. 2004
    ....
  12. ncbi Differential dynamics of dinophysistoxins and pectenotoxins between blue mussel and common cockle: a phenomenon originating from the complex toxin profile of Dinophysis acuta
    Paulo Vale
    Instituto Nacional de Investigação Agrária e das Pescas, IPIMAR, Av Brasilia, Lisboa 1449 006, Portugal
    Toxicon 44:123-34. 2004
    ..The isomerization was also observed with DTX2 esters present in mussel, but thus not appear to occur with the same extent with free DTX2...
  13. ncbi Dinophysistoxin-2: a rare diarrhoeic toxin associated with Dinophysis acuta
    P Vale
    Instituto de Investigação das Pescas e do Mar, Lisboa, Portugal
    Toxicon 38:1599-606. 2000
    ..Differences in toxicity levels may reflect different cell toxicities and different non-toxic phytoplankton availability as food source to shellfish...
  14. ncbi Determination of paralytic shellfish toxins in Portuguese shellfish by automated pre-column oxidation
    P Vale
    Instituto de Investigação das Pescas e do Mar, Av Brasilia, 1400 049, Lisboa, Portugal
    Toxicon 39:561-71. 2001
    ....
  15. ncbi Domoic acid in Portuguese shellfish and fish
    P Vale
    Instituto de Investigação das Pescas e do Mar, Av Brasilia, 1400 049 Lisbon, Portugal
    Toxicon 39:893-904. 2001
    ..In brain tissue, domoic acid was detected in levels generally below 1 microg/g. Domoic acid was confirmed by spectra acquired with a diode-array detector. The most toxic samples were confirmed by mass spectrometry...
  16. ncbi Esterification of DSP toxins by Portuguese bivalves from the Northwest coast determined by LC-MS--a widespread phenomenon
    Paulo Vale
    Instituto de Investigação das Pescas e do Mar, Av Brasilia, 1449 006, Lisboa, Portugal
    Toxicon 40:33-42. 2002
    ..The previous association of DTX2 with the dinoflagellate Dinophysis acuta was confirmed with selective MS detection; while OA was the only parent diarrhoeic toxin found associated with Dinophysis acuminata...
  17. doi Profiles of fatty acids and 7-O-acyl okadaic acid esters in bivalves: can bacteria be involved in acyl esterification of okadaic acid?
    Paulo Vale
    Instituto Nacional dos Recursos Biológicos, I P L IPIMAR, Avenida de Brasília s n, Lisbon, Portugal
    Comp Biochem Physiol C Toxicol Pharmacol 151:18-24. 2010
    ..Extensive esterification of OA by, among others, phytol-degrading bacteria is discussed as a plausible hypothesis in cockle, but not in mussel, due to the relatively high specific proportion of odd-numbered and branched FA...
  18. ncbi Evaluation of marine biotoxin's accumulation by Acanthocardia tuberculatum from Algarve, Portugal
    Paulo Vale
    Instituto de Investigação das Pescas e do Mar, Av Brasilia, 1449 006, Lisbon, Portugal
    Toxicon 40:511-7. 2002
    ..The diarrhoeic toxin okadaic acid was found at trace levels much under the allowable level, similar to what was happening with other species harvested during the same period...
  19. ncbi Pectenotoxin-2 seco acid, 7-epi-pectenotoxin-2 seco acid and pectenotoxin-2 in shellfish and plankton from Portugal
    Paulo Vale
    Instituto de Investigação das Pescas e do Mar, Av Brasilia, 1449 006 Lisbon, Portugal
    Toxicon 40:979-87. 2002
    ..In plankton extracts the most abundant pectenotoxin found was PTX2. Concentration of PTX2sa was around 10% of PTX2, and 7-epi-PTX2sa was not detected...
  20. ncbi First confirmation of human diarrhoeic poisonings by okadaic acid esters after ingestion of razor clams (Solen marginatus) and green crabs (Carcinus maenas) in Aveiro lagoon, Portugal and detection of okadaic acid esters in phytoplankton
    Paulo Vale
    Instituto de Investigação das Pescas e do Mar, Av Brasilia, 1449 006 Lisboa, Portugal
    Toxicon 40:989-96. 2002
    ..Percentages between 40-60% of esterified OA were found in samples freshly extracted. Ester's percentage diminished drastically if after sonication the extract was kept at room temperature. The major part of the esters was water-soluble...
  21. ncbi Seasonality of diarrhetic shellfish poisoning at a coastal lagoon in Portugal: rainfall patterns and folk wisdom
    Paulo Vale
    Instituto de Investigação das Pescas e do Mar, Av Brasilia, 1449 006, Lisboa, Portugal
    Toxicon 41:187-97. 2003
    ..The seasonality of DSP recurrence may be connected to the folk adage on safety of shellfish consumption, after many years of empirical observations by coastal populations of diarrhoea episodes in summertime...
  22. doi Extraction recoveries and stability of diarrhetic shellfish poisoning (DSP) toxins in naturally contaminated samples
    S M Rodrigues
    Instituto Nacional dos Recursos Biologicos IPIMAR, Lisbon, Portugal
    Food Addit Contam Part A Chem Anal Control Expo Risk Assess 26:229-35. 2009
    ..The recovery of DSP toxins increased with increasing percentages of methanol up to 90%. A decrease in recovery with 100% methanol was observed probably due to problems during the liquid-liquid partitioning...
  23. ncbi Spatial and temporal evolution of PSP toxins along the Atlantic shore of Morocco
    Hamid Taleb
    Institut National de Recherche Halieutique 2, Rue de Tiznit, Casablanca, Morocco
    Toxicon 41:199-205. 2003
    ..A minor contamination by G. catenatum due to the presence of decarbamoyl-saxitoxin is hypothesized...
  24. ncbi Comparative study on differential accumulation of PSP toxins between cockle (Acanthocardia tuberculatum) and sweet clam (Callista chione)
    Reqia Sagou
    Institut National de Recherche Halieutique, 2 rue Tiznit, Casablanca, Morocco
    Toxicon 46:612-8. 2005
    ..Substantial differences in toxin profile between cockle and sweet clam, from the same area as well as from the composition of PSP toxin producer, Gymnodinium catenatum, confirm the bioconversion of PSP toxins in cockle...
  25. doi Complex profiles of hydrophobic paralytic shellfish poisoning compounds in Gymnodinium catenatum identified by liquid chromatography with fluorescence detection and mass spectrometry
    Paulo Vale
    Instituto Nacional dos Recursos Biologicos IPIMAR, Avenida de Brasília s n, 1449 006 Lisbon, Portugal
    J Chromatogr A 1195:85-93. 2008
    ..The first sub-group was hypothesized to constitute an additional novel family of GC analogues with a hydroxysulfate group instead of the hydroxyl group in the benzoate side chain, tentatively designated GC1b-GC6b...
  26. doi First toxicity report of tetrodotoxin and 5,6,11-trideoxyTTX in the trumpet shell Charonia lampas lampas in Europe
    Paula Rodriguez
    Departamento de Farmacologia, Facultad de Veterinaria, Universidad de Santiago de Compostela, 27002, Lugo, Spain
    Anal Chem 80:5622-9. 2008
    ..The LC-MS method is a useful tool to confirm the presence of TTX and the further identification of TTX analogues...