Catia Teixeira

Summary

Affiliation: University of Aveiro
Country: Portugal

Publications

  1. doi request reprint Is the conformational flexibility of piperazine derivatives important to inhibit HIV-1 replication?
    Catia Teixeira
    Univ Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086, CNRS, 15 rue Jean Antoine de Baif, F 75205 Paris, France
    J Mol Graph Model 44:91-103. 2013
  2. ncbi request reprint Development of Plasmodium falciparum protease inhibitors in the past decade (2002-2012)
    B Perez
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Universidade do Porto, R do Campo Alegre, 687, P 4169 007 Porto, Portugal
    Curr Med Chem 20:3049-68. 2013
  3. doi request reprint Molecular docking and 3D-quantitative structure activity relationship analyses of peptidyl vinyl sulfones: Plasmodium Falciparum cysteine proteases inhibitors
    Catia Teixeira
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica, Portugal
    J Comput Aided Mol Des 25:763-75. 2011
  4. doi request reprint N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads
    Bianca C Pérez
    Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Centro de Investigação em Química da Universidade do Porto, Universidade do Porto, R do Campo Alegre 687, P 4169 007 Porto, Portugal
    J Med Chem 56:556-67. 2013
  5. doi request reprint In vitro efficiency of 9-(N-cinnamoylbutyl)aminoacridines against blood- and liver-stage malaria parasites
    Bianca Perez
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Universidade do Porto, R do Campo Alegre, 687, P 4169 007 Porto, Portugal
    Bioorg Med Chem Lett 23:610-3. 2013
  6. ncbi request reprint Toward the discovery of inhibitors of babesipain-1, a Babesia bigemina cysteine protease: in vitro evaluation, homology modeling and molecular docking studies
    Bianca Perez
    Departamento de Quimica, Faculdade de Ciencias, Centro de Investigação em Química da Universidade do Porto, Universidade do Porto, R Campo Alegre, 687, 4169 007, Porto, Portugal
    J Comput Aided Mol Des 27:823-35. 2013
  7. doi request reprint Novel cinnamic acid/4-aminoquinoline conjugates bearing non-proteinogenic amino acids: towards the development of potential dual action antimalarials
    Bianca C Pérez
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Universidade do Porto, R do Campo Alegre, 687, P 4169 007 Porto, Portugal
    Eur J Med Chem 54:887-99. 2012
  8. doi request reprint Molecular modeling studies of N-substituted pyrrole derivatives--potential HIV-1 gp41 inhibitors
    Catia Teixeira
    ITODYS, University Paris 7 CNRS UMR 7086, 1 rue Guy de la Brosse, 75005 Paris, France
    Bioorg Med Chem 16:3039-48. 2008
  9. doi request reprint Cinnamic acid/chloroquinoline conjugates as potent agents against chloroquine-resistant Plasmodium falciparum
    Bianca Perez
    Centro de Investigacao em Quimica, Departamento de Química e Bioquímic, Faculdade de Ciencias da Universidade do Porto, R do Campo Alegre, 4169 007 Porto, Portugal
    ChemMedChem 7:1537-40. 2012
  10. doi request reprint Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug
    Catia Teixeira
    ITODYS, Universite Paris Diderot, CNRS UMR7086, 15 rue Jean Antoine de Baif, 75205 Paris Cedex 13, France
    Eur J Med Chem 46:979-92. 2011

Collaborators

Detail Information

Publications12

  1. doi request reprint Is the conformational flexibility of piperazine derivatives important to inhibit HIV-1 replication?
    Catia Teixeira
    Univ Paris Diderot, Sorbonne Paris Cité, ITODYS, UMR 7086, CNRS, 15 rue Jean Antoine de Baif, F 75205 Paris, France
    J Mol Graph Model 44:91-103. 2013
    ..These new insights at the atomic level might be useful to design inhibitors with improved antiviral activity. ..
  2. ncbi request reprint Development of Plasmodium falciparum protease inhibitors in the past decade (2002-2012)
    B Perez
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Universidade do Porto, R do Campo Alegre, 687, P 4169 007 Porto, Portugal
    Curr Med Chem 20:3049-68. 2013
    ..falciparum protease inhibitors is a promising approach to antimalarial chemotherapy, as highlighted by the present review which is focused on the Medicinal Chemistry research effort recorded in the past decade in this particular field. ..
  3. doi request reprint Molecular docking and 3D-quantitative structure activity relationship analyses of peptidyl vinyl sulfones: Plasmodium Falciparum cysteine proteases inhibitors
    Catia Teixeira
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica, Portugal
    J Comput Aided Mol Des 25:763-75. 2011
    ..The present work provides extremely useful guidelines for future structural modifications of this class of compounds towards the development of superior antimalarials...
  4. doi request reprint N-cinnamoylated chloroquine analogues as dual-stage antimalarial leads
    Bianca C Pérez
    Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Centro de Investigação em Química da Universidade do Porto, Universidade do Porto, R do Campo Alegre 687, P 4169 007 Porto, Portugal
    J Med Chem 56:556-67. 2013
    ..Therefore, the compounds reported represent a new entry as promising dual-stage antimalarial leads...
  5. doi request reprint In vitro efficiency of 9-(N-cinnamoylbutyl)aminoacridines against blood- and liver-stage malaria parasites
    Bianca Perez
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Universidade do Porto, R do Campo Alegre, 687, P 4169 007 Porto, Portugal
    Bioorg Med Chem Lett 23:610-3. 2013
    ..The compounds were not toxic to human hepatoma cells at concentrations up to 5 μM. Hence, 9-(N-cinnamoylbutyl)aminoacridines are a new class of leads for prevention and treatment of malaria...
  6. ncbi request reprint Toward the discovery of inhibitors of babesipain-1, a Babesia bigemina cysteine protease: in vitro evaluation, homology modeling and molecular docking studies
    Bianca Perez
    Departamento de Quimica, Faculdade de Ciencias, Centro de Investigação em Química da Universidade do Porto, Universidade do Porto, R Campo Alegre, 687, 4169 007, Porto, Portugal
    J Comput Aided Mol Des 27:823-35. 2013
    ..Results presented herein provide a valuable contribution to future computer-aided molecular design of new babesipain-1 inhibitors. ..
  7. doi request reprint Novel cinnamic acid/4-aminoquinoline conjugates bearing non-proteinogenic amino acids: towards the development of potential dual action antimalarials
    Bianca C Pérez
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Universidade do Porto, R do Campo Alegre, 687, P 4169 007 Porto, Portugal
    Eur J Med Chem 54:887-99. 2012
    ..These novel conjugates constitute promising leads for the development of new antiplasmodials targeted at blood-stage malaria parasites...
  8. doi request reprint Molecular modeling studies of N-substituted pyrrole derivatives--potential HIV-1 gp41 inhibitors
    Catia Teixeira
    ITODYS, University Paris 7 CNRS UMR 7086, 1 rue Guy de la Brosse, 75005 Paris, France
    Bioorg Med Chem 16:3039-48. 2008
    ..These findings provide guidance for the design and structural modifications of these derivatives for better anti-HIV-1 activity which is important for the development of a new class of entry inhibitors...
  9. doi request reprint Cinnamic acid/chloroquinoline conjugates as potent agents against chloroquine-resistant Plasmodium falciparum
    Bianca Perez
    Centro de Investigacao em Quimica, Departamento de Química e Bioquímic, Faculdade de Ciencias da Universidade do Porto, R do Campo Alegre, 4169 007 Porto, Portugal
    ChemMedChem 7:1537-40. 2012
    ....
  10. doi request reprint Viral surface glycoproteins, gp120 and gp41, as potential drug targets against HIV-1: brief overview one quarter of a century past the approval of zidovudine, the first anti-retroviral drug
    Catia Teixeira
    ITODYS, Universite Paris Diderot, CNRS UMR7086, 15 rue Jean Antoine de Baif, 75205 Paris Cedex 13, France
    Eur J Med Chem 46:979-92. 2011
    ....
  11. ncbi request reprint Flexible computational docking studies of new aminoglycosides targeting RNA 16S bacterial ribosome site
    Florent Barbault
    ITODYS, Universite Paris Diderot, CNRS UMR 7086, 1 rue Guy de la Brosse, 75005 Paris, France
    Eur J Med Chem 43:1648-56. 2008
    ..The overall results showed that the consideration of the RNA dynamic behavior is of great interest...
  12. doi request reprint Recycling antimalarial leads for cancer: Antiproliferative properties of N-cinnamoyl chloroquine analogues
    Bianca C Pérez
    Centro de Investigação em Química da Universidade do Porto, Departamento de Quimica e Bioquimica, Faculdade de Ciencias, Universidade do Porto, Rua do Campo Alegre 687, P 4169 007 Porto, Portugal
    Bioorg Med Chem Lett 23:6769-72. 2013
    ..Hence, N-cinnamoyl-chloroquine analogues are a good start towards development of affordable antitumor leads. ..