Research Topics
| Ana FariaSummaryAffiliation: University of Porto Country: Portugal Publications
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Detail Information
Publications
Flavonoid transport across RBE4 cells: A blood-brain barrier modelAna Faria
Department of Biochemistry, University of Porto, Portugal
Cell Mol Biol Lett 15:234-41. 2010..This transport was not influenced by the presence of 0.1% ethanol. In conclusion, the tested flavonoids were capable of crossing this blood-brain barrier model...
Intestinal oxidative state can alter nutrient and drug bioavailabilityAna Faria
University of Porto, Porto, Portugal
Oxid Med Cell Longev 2:322-7. 2009..The results indicate that modifications in the cellular oxidative state modulate MPP+ uptake by Caco-2 cells. Such modifications may reflect in changes of nutrient and drug bioavailability...- Blueberry anthocyanins and pyruvic acid adducts: anticancer properties in breast cancer cell linesAna Faria
Department of Biochemistry U38 FCT, Faculty of Medicine of the University of Porto, 4200 319 Porto, Portugal
Phytother Res 24:1862-9. 2010..The anthocyanin-pyruvic acid adduct extract showed a more pronounced effect in MDA-MB-231, suggesting an effect independent of estrogen receptors... - Impact of culture media glucose levels on the intestinal uptake of organic cationsAna Faria
Department of Biochemistry, Faculty of Medicine, University of Porto, Alameda Prof Hernani Monteiro, 4200 319, Porto, Portugal
Cytotechnology 62:23-9. 2010..Hence, results obtained in these conditions must be analysed with great care, since extracellular glucose levels may originate changes in organic cation nutrient and drug bioavailability... - The bioactivity of pomegranate: impact on health and diseaseAna Faria
Biochemistry Department U38 FCT, Faculty of Medicine, University of Porto, 4200 319, Porto, Portugal
Crit Rev Food Sci Nutr 51:626-34. 2011..In addition, pomegranate inhibits the activation of inflammatory pathways including, but not limited to, the NFκ-B pathway. Anti-cancer effects with the most impressive data have been demonstrated so far in prostate cancer... - Absorption of anthocyanins through intestinal epithelial cells - Putative involvement of GLUT2Ana Faria
Department of Chemistry, Chemistry Investigation Centre, University of Porto, Portugal
Mol Nutr Food Res 53:1430-7. 2009..However, the malvidin aglycone was tested and had no effect. In conclusion, anthocyanins could be absorbed through Caco-2 cells, and can interfere with their own transport and also with glucose intestinal uptake... - Insights into the putative catechin and epicatechin transport across blood-brain barrierAna Faria
Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Al Prof Hernani Monteiro, 4200 319 Porto, Portugal
Food Funct 2:39-44. 2011.... 
Effect of pomegranate (Punica granatum) juice intake on hepatic oxidative stressAna Faria
Dept of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Al Prof Hernani Monteiro, 4200 319, Porto, Portugal
Eur J Nutr 46:271-8. 2007..Additionally, RT-PCR results showed that GST and GS transcription were also decreased in this group. These results are compatible with a protective effect of PJ against systemic oxidative stress in mice...- Pomegranate juice effects on cytochrome P450S expression: in vivo studiesAna Faria
Department of Biochemistry, Faculty of Medicine, University of Porto, Porto, Portugal
J Med Food 10:643-9. 2007..Prevention of procarcinogen activation through CYP activity/expression inhibition may be involved in pomegranate juice's effect on tumor initiation, promotion, and progression... - Red wine interferes with oestrogen signalling in rat hippocampusRosario Monteiro
Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Alameda Prof Hernani Monteiro, 4200 319 Porto, Portugal
J Steroid Biochem Mol Biol 111:74-9. 2008..Alterations in the relative abundance of ER expression may also play an important role in the protection... - Influence of anthocyanins, derivative pigments and other catechol and pyrogallol-type phenolics on breast cancer cell proliferationIva Fernandes
Chemistry Investigation Centre CIQ, Department of Chemistry, Faculty of Sciences, University of Porto, Porto, Portugal
J Agric Food Chem 58:3785-92. 2010..However, the anthocyanin Cy-3-gluc was able to induce a downregulation of ER levels although with no significant effect on MCF-7 proliferation... - Enzymatic hemisynthesis of metabolites and conjugates of anthocyaninsIva Fernandes
Chemistry Investigation Centre, Department of Chemistry, University of Porto, Portugal
J Agric Food Chem 57:735-45. 2009.... - Procyanidins as antioxidants and tumor cell growth modulatorsAna Faria
Chemistry Investigation Centre, Department of Chemistry, Faculty of Sciences, University of Porto, 4169-007 Porto, Portugal
J Agric Food Chem 54:2392-7. 2006..It is interesting to notice that the procyanidin fractions that exhibited higher antioxidant activity were the same to affect cell viability and proliferation... - Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupulus L.) flavonoidsRosario Monteiro
Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Alameda Prof Hernani Monteiro, 4200 319 Porto, Portugal
J Steroid Biochem Mol Biol 105:124-30. 2007.... - Thiamine is a substrate of organic cation transporters in Caco-2 cellsClara Lemos
Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, 4200 319 Porto, Portugal
Eur J Pharmacol 682:37-42. 2012.... - Modulation of adipocyte biology by δ(9)-tetrahydrocannabinolDiana Teixeira
Department of Biochemistry U38 FCT, Faculty of Medicine, University of Porto, Porto, Portugal
Obesity (Silver Spring) 18:2077-85. 2010..Although these observations point toward increased AT deposition, the stimulation of adiponectin production and inhibition of lipolysis may be in favor of improved INS sensitivity under cannabinoid influence... - Optimization and validation of organochlorine compounds in adipose tissue by SPE-gas chromatographyVirginia C Fernandes
REQUIMTE, Instituto Superior de Engenharia, Instituto Politécnico do Porto, Rua Dr António Bernardino de Almeida 431, 4200 072, Porto, Portugal
Biomed Chromatogr 26:1494-501. 2012..The highest percentage found of the OCC in real samples corresponded to HCB, o,p'-DDT and methoxychlor, which were detected in 80 and 95% of samples analyzed respectively... - Modulation of MPP+ uptake by procyanidins in Caco-2 cells: involvement of oxidation/reduction reactionsAna Faria
Department of Biochemistry (U38-FCT, Faculty of Medicine of the University of Porto, Al. Prof. Hernani Monteiro, 4200-319 Porto, Portugal
FEBS Lett 580:155-60. 2006..Interactions between these compounds and drugs present in the diet may affect their absorption and bioavailability. Both the concentration and complexity of the procyanidin compounds should be taken into account in medical practice... - Acute effect of tea, wine, beer, and polyphenols on ecto-alkaline phosphatase activity in human vascular smooth muscle cellsMaria R Negrão
Department of Biochemistry, Faculty of Medicine U38 FCT, University of Porto, 4200 319 Porto, Portugal
J Agric Food Chem 54:4982-8. 2006..Although more studies must be done, the inhibition of AALTR ecto-ALP activity by polyphenolic compounds and polyphenol-containing beverages may contribute to their cardiovascular protective effects...