Moises Mallo

Summary

Country: Portugal

Publications

  1. pmc Hox genes and regional patterning of the vertebrate body plan
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    Dev Biol 344:7-15. 2010
  2. ncbi request reprint Controlled gene activation and inactivation in the mouse
    Moises Mallo
    Instituto Gulbenkian de Ciencia, 2780 156 Oeiras, Portugal
    Front Biosci 11:313-27. 2006
  3. ncbi request reprint Reversible gene inactivation in the mouse
    Moises Mallo
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Freiburg, Germany
    Genomics 81:356-60. 2003
  4. doi request reprint The road to the vertebral formula
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    Int J Dev Biol 53:1469-81. 2009
  5. ncbi request reprint And the segmentation clock keeps ticking
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    Bioessays 29:412-5. 2007
  6. pmc A look at life from the homeodomain. Workshop on homeodomain proteins, hematopoietic development and leukemias
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    EMBO Rep 7:976-80. 2006
  7. ncbi request reprint A novel possible mechanism for the genesis of genomic duplications and its experimental test
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780, Oeiras, Portugal
    J Mol Evol 61:390-7. 2005
  8. ncbi request reprint Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development
    Filipa Moraes
    Instituto Gulbenkian de Ciencia, UT, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    Mech Dev 122:199-212. 2005
  9. pmc Hox genes specify vertebral types in the presomitic mesoderm
    Marta Carapuco
    Instituto Gulbenkian de Ciencia, 2780 156 Oeiras, Portugal
    Genes Dev 19:2116-21. 2005
  10. ncbi request reprint Hoxa2 downregulates Six2 in the neural crest-derived mesenchyme
    Eva Kutejova
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Stuebeweg 51, 79108 Freiburg, Germany
    Development 132:469-78. 2005

Collaborators

Detail Information

Publications19

  1. pmc Hox genes and regional patterning of the vertebrate body plan
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    Dev Biol 344:7-15. 2010
    ..The control of these functions must have been intimately linked to the shaping of the body plan during evolution...
  2. ncbi request reprint Controlled gene activation and inactivation in the mouse
    Moises Mallo
    Instituto Gulbenkian de Ciencia, 2780 156 Oeiras, Portugal
    Front Biosci 11:313-27. 2006
    ..The Cre/lox and FLP/FRT systems are the most popular of these. I will discuss how these recombination systems are used in the mouse with special focus on their use to achieve specific gene activation...
  3. ncbi request reprint Reversible gene inactivation in the mouse
    Moises Mallo
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Freiburg, Germany
    Genomics 81:356-60. 2003
    ..This procedure allows the production of gene inactivation that is complete, is reversible, and can be controlled at the spatial and temporal levels...
  4. doi request reprint The road to the vertebral formula
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    Int J Dev Biol 53:1469-81. 2009
    ..The possible connections between Hox genes and all these signalling processes to generate a properly patterned axial skeleton are discussed in this review...
  5. ncbi request reprint And the segmentation clock keeps ticking
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    Bioessays 29:412-5. 2007
    ..have now shown that the segmentation clock is more complex than previously thought and includes oscillating expression of genes from at least three signaling pathways organized in coordinated networks...
  6. pmc A look at life from the homeodomain. Workshop on homeodomain proteins, hematopoietic development and leukemias
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    EMBO Rep 7:976-80. 2006
  7. ncbi request reprint A novel possible mechanism for the genesis of genomic duplications and its experimental test
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780, Oeiras, Portugal
    J Mol Evol 61:390-7. 2005
    ..The model presented represents a novel mechanistic pathway that can explain a variety of rearrangements, including genomic tandem duplications and deletions...
  8. ncbi request reprint Tbx1 is required for proper neural crest migration and to stabilize spatial patterns during middle and inner ear development
    Filipa Moraes
    Instituto Gulbenkian de Ciencia, UT, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    Mech Dev 122:199-212. 2005
    ..The inability of the Tbx1(-/-) embryos to keep properly segregated functional domains in the otocyst is likely the cause of the strong inner ear phenotypes observed in these mutants...
  9. pmc Hox genes specify vertebral types in the presomitic mesoderm
    Marta Carapuco
    Instituto Gulbenkian de Ciencia, 2780 156 Oeiras, Portugal
    Genes Dev 19:2116-21. 2005
    ....
  10. ncbi request reprint Hoxa2 downregulates Six2 in the neural crest-derived mesenchyme
    Eva Kutejova
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Stuebeweg 51, 79108 Freiburg, Germany
    Development 132:469-78. 2005
    ..Furthermore, we demonstrate that Hoxa2 regulation of Six2 is confined to a 0.9 kb fragment of the Six2 promoter and that Hoxa2 binds to this promoter region. These results strongly suggest that Six2 is a direct target of Hoxa2...
  11. doi request reprint Evidence for a myotomal Hox/Myf cascade governing nonautonomous control of rib specification within global vertebral domains
    Tânia Vinagre
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    Dev Cell 18:655-61. 2010
    ..Our findings offer a new perspective of how Hox genes produce global patterns in the axial skeleton and support a redundant nonmyogenic role of Myf5 and Myf6 in rib formation...
  12. doi request reprint Switching axial progenitors from producing trunk to tail tissues in vertebrate embryos
    Arnon Dias Jurberg
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    Dev Cell 25:451-62. 2013
    ..Our findings provide a perspective to understand the evolution of the vertebrate body plan...
  13. ncbi request reprint Bmp2 is required for migration but not for induction of neural crest cells in the mouse
    Ana Catarina Correia
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    Dev Dyn 236:2493-501. 2007
    ..Finally, our data suggest that the molecular cascade downstream of BMP signaling in early neural crest development may be different in mouse and avian embryos...
  14. ncbi request reprint Aortic arch and pharyngeal phenotype in the absence of BMP-dependent neural crest in the mouse
    Sabine Ohnemus
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Freiburg, Germany
    Mech Dev 119:127-35. 2002
    ....
  15. pmc Role of a polymorphism in a Hox/Pax-responsive enhancer in the evolution of the vertebrate spine
    Isabel Guerreiro
    Instituto Gulbenkian de Ciencia, 2780 156 Oeiras, Portugal
    Proc Natl Acad Sci U S A 110:10682-6. 2013
    ..These results suggest that a polymorphism in the Hox/Pax-responsive enhancer may have played a role in the evolution of the vertebrate spine by differently modulating its response to rib-suppressing and rib-promoting Hox proteins. ..
  16. ncbi request reprint Mesenchymal patterning by Hoxa2 requires blocking Fgf-dependent activation of Ptx1
    Nicoletta Bobola
    Department of Developmental Biology, Max Planck Institute of Immunobiology, Freiburg, Germany
    Development 130:3403-14. 2003
    ....
  17. ncbi request reprint Formation of the outer and middle ear, molecular mechanisms
    Moises Mallo
    Instituto Gulbenkian de Ciencia, Rua da Quinta Grande 6, 2780 156 Oeiras, Portugal
    Curr Top Dev Biol 57:85-113. 2003
  18. ncbi request reprint Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia
    Albert Gründer
    Institut fur Biologie III, Albert Ludwigs Universitat, Freiburg, Germany
    Mech Dev 112:69-77. 2002
    ..Our study demonstrates that Nfib is essential for normal lung development, and suggests that it could be involved in the pathogenesis of respiratory distress syndromes in humans...
  19. doi request reprint Controlling Hox gene expression and activity to build the vertebrate axial skeleton
    Ana Casaca
    Instituto Gulbenkian de Ciencia, Oeiras, Portugal
    Dev Dyn 243:24-36. 2014
    ..Exciting new findings will surely emerge in the years ahead. Developmental Dynamics 243:24-36, 2014. © 2013 Wiley Periodicals, Inc. ..